| characterization of various horse thyroid forms of cyclic-nucleotide phosphodiesterase [proceedings]. | | 1979 | 92956 |
| isoelectric focusing of oligopeptides: detection by specific stains. | by using ultrathin (350 micrometers) polyacrylamide gels, which at the end of the fractionation are pasted to filter paper and dried in an oven at 110 degrees c, and after isoelectric focusing it has been possible to detect oligopeptides in the di- to tetradecapeptide range, which could not be detected by protein staining techniques. this is achieved by developing a series of specific stains for the following amino acids: arg, tyr, his, trp, met and cys. except for met and cys, the detection lim ... | 1979 | 95344 |
| site dependence for topical absorption of nitroglycerin in rats. | | 1978 | 99511 |
| the effect of amino acids, carbohydrate and fat emulsion on the metabolism in gastrectomized patients. | nitrogen balance and other metabolic activity can be maintained by adequate calorie and protein supply during immediate postgastrectomy period. despite high intake of protein, great loss of nitrogen seems to occur in urine during infusion with polyalcohol sugars as compared with natural sugars, e.g., glucose, fructose and maltose. the best utilization of amino acids resulting in positive nitrogen balance and energy utilization were shown to be achieved by combined use of intralipid, glucose, mal ... | 1977 | 404454 |
| polymorphism in a t-cell receptor variable gene is associated with susceptibility to a juvenile rheumatoid arthritis subset. | this report demonstrates a t-cell receptor (tcr) restriction fragment length polymorphism, defined by a tcrb-v6.1 gene probe and bgl ii restriction enzyme, to be absolutely correlated with allelic variation in the coding sequence of a tcrb-v6.1 gene. a pair of non-conservative amino acid substitutions distinguish the tcrb-v6.1 allelic variants. an association of this tcrb-v6.1 gene allelic variant with one form of juvenile rheumatoid arthritis (jra) was established in a cohort of 126 patients. t ... | 1992 | 1347283 |
| influence of low-temperature storage and glucose starvation on growth recovery in escherichia coli rela and rela+ strains. | to study the influence of microgravity on bacterial growth behavior during a space mission, the special experimental conditions and the hardware environment necessitate storage of cells at low temperature, and permit a relatively short experimental period. before this experimental period, cells have to recover their condition of steady-state growth, because it is only in this condition that the growth behavior of the flight and ground populations can be adequately compared. to meet these require ... | 1991 | 1367237 |
| effects of sodium selenite and caffeine on mutagenesis induced by n-methyl-n-nitrosourea, n-methyl-n'-nitro-n-nitrosoguanidine and aflatoxin b1 in s. typhimurium. | pre-treatment, co-treatment, and post-treatment procedures were comparatively used in order to assess the modulation of mutagenicity in s. typhimurium his- strains. pre-treatment of bacteria with sodium selenite had no effect on sodium azide mutagenicity. irrespective of the procedure used neither selenite nor caffeine had any influence on the s9-mediated mutagenicity of aflatoxin b1. in contrast, the mutagenicity of n-methyl-n-nitrosourea (mnu) and n-methyl-n'-nitro-n- nitrosoguanidine (mnng) w ... | 1992 | 1383715 |
| sequence identification of 2,375 human brain genes. | we recently described a new approach for the rapid characterization of expressed genes by partial dna sequencing to generate 'expressed sequence tags'. from a set of 600 human brain complementary dna clones, 348 were informative nuclear-encoded messenger rnas. we have now partially sequenced 2,672 new, independent cdna clones isolated from four human brain cdna libraries to generate 2,375 expressed sequence tags to nuclear-encoded genes. these sequences, together with 348 brain expressed sequenc ... | 1992 | 1538749 |
| effects of amobarbital on pterins and dinucleotides contents in rat brain. | the effects of amobarbital (50 mg.kg-1 ip) on the brain concentrations of biopterin, pterin, reduced nicotinamide adenine dinucleotide (nadh) and flavin adenine dinucleotide (fad) were studied by a reverse phase high performance liquid chromatography with fluorescent detector. amobarbital increased fad concentrations in 5 brain areas and pterin concentration in the cortex, but decreased biopterin concentrations in the cortex and hippocampus. | 1991 | 1950577 |
| cytotoxic and cytostatic effects of arecoline and sodium nitrite on human cells in vitro. | arecoline, an active alkaloid of areca catechu l., and sodium nitrite, a food additive, are highly cytotoxic and cytostatic on the hep 2 cell line when administered in an acidic environment (ph 4.2) in the presence of s-9 mixture. hep 2 cells (10(6)) were treated with either 0.145, 0.725 or 1.449 mm sodium nitrite or 0.042, 0.085 or 0.339 mm arecoline or sodium nitrite (0.145 mm) plus varied concentrations of arecoline (0.042, 0.085 or 0.339 mm). their effects were additive in nature. hep 2 cell ... | 1991 | 1993547 |
| interaction of a 60-kilodalton d-mannose-containing salivary glycoprotein with type 1 fimbriae of escherichia coli. | a 60-kilodalton glycoprotein previously isolated and purified from human saliva (j. b. babu, e. h. beachey, d. l. hasty, and w. a. simpson, infect. immun. 51: 405-413, 1986) was found to interact with type 1 fimbriae and prevent adhesion of type 1 fimbriated escherichia coli to animal cells in a d-mannose-sensitive manner. purified salivary glycoprotein agglutinated type 1 fimbriated e. coli and, at subagglutinating concentrations, blocked the ability of type 1 fimbriated e. coli to attach to hu ... | 1986 | 2875948 |
| penicillinase-producing neisseria gonorrhoeae in various seaport cities of latin america. | one hundred fifteen acute cases of gonorrhea were documented in u.s. military personnel during a five-month cruise in which 22 port cities of latin america were visited in 1985. penicillinase-producing neisseria gonorrhoeae (ppng) was isolated from 23 (20%) of the 115 cases. no penicillin-resistant, beta-lactamase-negative gonococci were encountered. none of the ten cases of gonorrhea acquired in the caribbean region was due to ppng. in south america, the ppng infection rate was 35% (19/54) in p ... | 1988 | 3147519 |
| haemolytic uraemic syndrome associated with faecal cytotoxin and verotoxin neutralizing antibodies. | forty-nine patients with a diagnosis of idiopathic haemolytic uraemic syndrome (hus) were investigated to determine evidence of infection by verotoxin-producing escherichia coli (vtec). free faecal cytotoxin active on vero cells (vt) was detected in 15 out of 49 patients (31%). seroconversion or high titres of vt-neutralizing antibodies were detected in 11 out of 18 patients (61%). the results of the present study suggest an association between hus and infection by vtec. | 1988 | 3153027 |
| comparison of two nonculture techniques for detection of hemophilus influenzae in sputum. in situ hybridization and immunoperoxidase staining with monoclonal antibodies. | two nonculture methods, in situ hybridization and immunoperoxidase staining with monoclonal antibodies, were compared for the detection of hemophilus influenzae in 184 sputa. for in situ hybridization, a biotin-labeled probe of total genomic dna of h influenzae type b was prepared that hybridizes specifically with h influenzae, h parainfluenzae, h hemolyticus, and h parahemolyticus dna. immunoperoxidase staining was done with monoclonal antibody 8bd9 directed against outer membrane protein p6 of ... | 1988 | 3293938 |
| comparison of two nonculture techniques for detection of hemophilus influenzae in sputum. in situ hybridization and immunoperoxidase staining with monoclonal antibodies. | two nonculture methods, in situ hybridization and immunoperoxidase staining with monoclonal antibodies, were compared for the detection of hemophilus influenzae in 184 sputa. for in situ hybridization, a biotin-labeled probe of total genomic dna of h influenzae type b was prepared that hybridizes specifically with h influenzae, h parainfluenzae, h hemolyticus, and h parahemolyticus dna. immunoperoxidase staining was done with monoclonal antibody 8bd9 directed against outer membrane protein p6 of ... | 1988 | 3293938 |
| the carrier state: group b streptococcus. | | 1986 | 3528112 |
| rearrangement and expression of erythropoietin genes in transformed mouse cells. | the erythroleukemia cell line iw32, derived by transformation with the friend murine leukemia virus, has been shown previously to produce erythropoietin (epo) constitutively. here we demonstrate that, in addition to the normal mouse epo locus, this cell line has another epo locus which has undergone rearrangement and amplification. both loci were cloned, and the rearrangement breakpoint of the second epo locus was located within a 1.1-kilobase region upstream of an otherwise apparently normal ep ... | 1987 | 3561395 |
| proceedings: cyclic gmp formation in human platelets. | | 1974 | 4152362 |
| cyclic amp formation and thyroid secretion by isolated mouse thyroid lobes. | | 1972 | 4344238 |
| [biochemical studies on human salivary proteins. xi. effect of saliva-parotin-a on phosphatase activities]. | | 1972 | 4347599 |
| insecticide inhibition of 5alpha-dihydrotestosterone binding in the rat ventral prostate. | the chlorinated hydrocarbon insecticides dieldrin and o,p'-ddt inhibit binding of 5alpha-dihydrotestosterone to specific receptor proteins in rat prostate cytosol. dieldrin is less inhibitory than o,p'-ddt. | 1973 | 4353358 |
| enzymatic maturation of mouse cerebral neocortex in vitro and in situ. | | 1970 | 4392272 |
| cross resistance of escherichia coli b ribosomes to inhibition of the puromycin reaction by erythromycin, spiramycin and chloramphenicol. | | 1968 | 4870247 |
| further characterization of the lens cell-free system. | | 1969 | 4891895 |
| when is serum albumin worth measuring? | | 2011 | 3214132 |
| what is a sealant restoration? | | 2011 | 3165270 |
| plutonium and lung cancer. | the national plutonium workers study surveys workers at three major u.s. department of energy facilities who were exposed to pu and other radioactive substances. the purpose of the study is to measure adverse health effects, if any, which arise from exposure. most exposures occur from inhalation of highly insoluble forms of plutonium oxide, and from animal studies, lung cancer is the most likely outcome. to date, the studies have shown that lung cancer mortality among highly exposed persons is s ... | 2012 | 3570799 |
| health care marketing. | | 2012 | 3899994 |
| radiographic signs of union of scaphoid fractures. an analysis of inter-observer agreement and reproducibility. | inter-observer agreement and reproducibility of opinion were assessed for the radiographic diagnosis of union of scaphoid fractures on films taken 12 weeks after injury. weighted kappa statistics were used to compare the opinions of eight senior observers reviewing 20 sets of good quality radiographs on two occasions separated by two months. there was poor agreement on whether trabeculae crossed the fracture line, whether there was sclerosis at or near the fracture and on whether the proximal pa ... | 2012 | 3346310 |
| [mycology technics]. | | 2013 | 3847144 |
| second-trimester abortion after vaginal termination of pregnancy. | | 2014 | 4115252 |
| [botanical and phytochemical investigations of species of the genus helleborus growing in europe and asian minor. iii. the quantitative contents of hellebrin in plants of the natural biotops and in culture (author's transl)]. | | 2015 | 4465819 |
| [artero-venous angiodysplasia at the splenic hylum: contribution to the knowledge of pre-hepatic artero-venous angiodysplasias with portal hypertension]. | | 2014 | 4080430 |
| influence of antibiotics on the faecal excretion of bile pigments in healthy subjects. | we have evaluated the effects of 10 antibiotics, given orally for 6 days to healthy subjects, on faecal excretion of urobilinogen. intake of bacitracin, vancomycin, clindamycin, erythromycin, and ampicillin resulted in a pronounced suppression of the faecal excretion of urobilinogen (p less than 0.05). intake of doxycycline, metronidazole, nalidixic acid, ofloxacin, and trimethoprim/sulphamethoxazole had no significant effect. the effects of three antibiotics-ampicillin, clindamycin, and metroni ... | 2013 | 3775264 |
| experimental studies of aqueous filtration using the molteno implant. | | 2012 | 3447338 |
| nephrotoxic drugs. | the nephrotoxic effects of cyclosporine, aminoglycoside antibiotics, cisplatin, amphotericin b, beta-lactam antibiotics and indomethacin are reviewed. these drugs were chosen because they are among the most frequent causes of renal injury in children. in addition, their nephrotoxicity is caused by different mechanisms. several generalizations can be made, however. first, agents which cause tubular damage tend to be synergistic in their toxic effects. this synergism is seen when several nephrotox ... | 2011 | 3153061 |
| simultaneous bilateral testicular tumors, one side clinically occult: detection by ultrasonography. | the majority of bilateral testicular tumors are discovered sequentially. some of these second tumors may be present subclinically at the time the initial contralateral tumor is diagnosed and their simultaneous detection with ultrasound screening would obviate the inherent problems of an otherwise sequential bilaterality. we report a case of simultaneous bilateral seminomas in which 1 of the 2 tumors was subclinical and detected with ultrasound. the various problems encountered with these asynchr ... | 2012 | 3511301 |
| [corrective treatment of immunodeficient conditions]. | | 2015 | 4423707 |
| intravascular synovial sarcoma. | a biphasic synovial sarcoma occurring in the wall of a pathologically thickened femoral vein was diagnosed in a 34-year-old woman. this sarcoma was resected together with removal of a thrombus. a local recurrence was seen 5 years later, but the patient is alive and well 11 years after the first operation. immunohistochemical evaluation revealed cytokeratin and epithelial membrane antigen in a portion of the tumor cells, as are typically seen in synovial sarcoma. this case shows that so-called sy ... | 2009 | 2820861 |
| [correction of severe postburn deformity of the lower extremity and its elongation by the method of distraction epiphysiolysis]. | | 2015 | 4423706 |
| [intal in the treatment of asthma. iii. long-term treatment of asthma]. | | 2000 | 101977 |
| [cytotoxic effect of sensitized lymphocytes on antigen content of target cells]. | | 2014 | 4109375 |
| seizures during infancy and childhood. | | 2014 | 4080432 |
| [cyclosporin a in corneal transplantation]. | | 2010 | 3048719 |
| [how long will preserved blood and bone marrow films give reliable cytochemical staining?]. | we tested how long unstained and unfixed films of blood and aspirated bone marrow could be kept before special cytochemical staining. to exclude influences other than time on the outcome of the reactions, all the material was taken from hematologically normal persons. a simple score was used to evaluate the results. these may be summarized as follows: in most cells naphthol-as-acetate-esterase first shows a progressive decline in reactivity after a delay of 6 weeks, the reaction becoming very we ... | 2008 | 2415749 |
| hickman catheter for haemodialysis in paediatric patients. | twelve hickman catheters were inserted in nine children in order to establish access for haemodialysis or plasmapheresis. catheters were implanted either through the external or internal jugular vein and the tip located in the right atrium or superior vena cava. mean blood flow was 25-55 ml/min with single lumen catheters and 83-100 ml/min with double lumen catheters. three catheters had to be removed because of obstruction, whilst seven remained in situ until an arteriovenous fistula had mature ... | 2011 | 3153034 |
| disseminated sporotrichosis. | the clinical manifestations of sporotrichosis can be classified into three disease patterns: (1) localized lymphatic sporotrichosis, (2) fixed cutaneous (or endemic) sporotrichosis, and (3) disseminated sporotrichosis. this presentation reflects a rare disseminated form of the disease with extensive cutaneous and systemic lesions, and further illustrates the difficulty in diagnosing systemic sporotrichosis infection. | 2012 | 3346121 |
| acupuncture treatment for aerotitis media. | | 2013 | 3834237 |
| in memoriam. robert nelson smith, jr., m.d., 1917-1971. | | 2015 | 4551191 |
| creatinine clearance evaluation in routine diabetes practice. | creatinine clearance measurement based on timed urine collection is not reliable in routine practice. methods for creatinine clearance estimation have already been established and validated in non diabetic patients. in order to ascertain their validity in diabetic patients, creatinine clearance values were determined in 33 diabetic patients (16 men, 17 women) on two consecutive days by direct measurement and by estimation according to the methods of kampmann et al., bjornsson et al. and cockcrof ... | 2012 | 3416557 |
| [ureteral ectopia in cysts of the seminal vesicle and renal agenesis. description of a case]. | | 2010 | 3238542 |
| effects of lsd-25 on avoidance behavior and locomotor activity in mice. | c57bl/6(c57) mice were tested in a shuttle box under the influence of lsd-25 in two sets of experiments. in the first set, the pretrial administrations of lsd (0.05, 0.1, and 0.2 mg/kg) were followed by dose-related performance improvements. in the second set, the posttrial administration of lsd (0.2 mg/kg) immediately after each experimental session improved the performances of the mice. no effect was evident when the hallucinogen was injected 2 h after training, thus showing that lsd improved ... | 2000 | 111278 |
| give diet a chance in lowering cholesterol levels. | | 2012 | 3365070 |
| bidirectional differentiation in a large cell pleomorphic primary endocrine carcinoma of the skin (a variant of malignant merkel cell tumour). | a primary endocrine carcinoma of the skin is described in which the tumour cells showed the unusual features of large size and marked nuclear pleomorphism. ultrastructural examination revealed combined features of squamous and endocrine differentiation in the same cells, a phenotype which has been previously anticipated but only recently described in endocrine carcinomas of the skin. in addition, immunocytochemical staining showed the co-expression of cytokeratin and neurofilament. the globular ... | 2013 | 3763247 |
| [is malignant mesothelioma of the pleura only an occupational disease?]. | ten cases of pleural malignant mesothelioma identified histologically at the department of general medicine in may 1983-june 1987, are examined in this paper. occupational risk factors and clinical features are discussed. only one patient (10%) was subjected to occupational risk of asbestos exposure (as a smith) while the other nine patients showed a negative anamnesis for direct or indirect asbestos exposure. however, one of these patients was a tram-driver. the patients' mean age was 69 years ... | 2010 | 2927705 |
| ocular compression by modified sphygmomanometer to produce hypotony. | | 2011 | 3155054 |
| [bone histomorphometry in monoclonal dysglobinemia. diagnostic and prognostic value]. | data of bony histomorphometry by transiliac biopsy were studied in 35 cases of multiple myeloma and 26 cases of benign monoclonal dysglobulinemia. in a first stage, the comparison between the two groups showed an osteoclastic resorption which was significantly higher in myeloma patients in osteolytic forms as well as asymptomatic forms, showing the diagnostic advantage of this measurement in these forms of the disease. also, the association of a preservation of the bony trabecular volume with an ... | 2013 | 3797975 |
| [hibidil]. | | 2013 | 3635236 |
| the role of host lymphocytes and host macrophages in antitumor reactions after injection of sensitized lymphocytes and tumor target cells into naive mice. | dba/2 mice were immunized i.p. against syngeneic sl2 lymphosarcoma cells. at various days after the last immunization peritoneal and spleen lymphocytes were collected. the lymphocyte suspensions were enriched for t-cells by nylon wool filtration. the peritoneal t-cells from immunized mice (a) expressed direct specific antitumor cytotoxicity in vitro, (b) induced macrophage cytotoxicity in vitro, and (c) exerted tumor neutralization measured in a winn-type assay. spleen t-cells from these immuniz ... | 2013 | 3536093 |
| the effects on exercise tolerance of a new transdermal therapeutic system containing nitroglycerine, in patients with stable angina pectoris. | in two randomized, double blind, placebo-controlled, within patient, studies, the effects of 4 doses of a new transdermal therapeutic system containing nitroglycerin (tts-ntg) were studied in a total of 15 patients with stable exercise-induced angina pectoris. a single 24-hour application of tts-ntg 10 cm2, tts-ntg 20 cm2 and tts placebo (1st study: 6 patients) and of tts-ntg 40 cm2, tts-ntg 80 cm2 and tts placebo (2nd study: 9 patients) was applied on 3 different days, and a symptom-limited cyc ... | 2011 | 3137062 |
| decreased tissue fibrinolytic activity in granuloma annulare. | | 2012 | 3504750 |
| randomized trial of cystectomy with or without preoperative radiotherapy for carcinoma of the bilharzial bladder. | a prospective randomized clinical trial was done for 92 patients with carcinoma of the bilharzial bladder who underwent radical cystectomy alone or with 2,000 rad preoperative radiation. the postoperative mortality and morbidity were similar in both groups. patients were followed for a minimum of 60 months. over-all, there was a marginal, statistically insignificant improvement in survival among patients receiving preoperative radiotherapy. nevertheless, 2 subpopulations demonstrated significant ... | 2013 | 3894693 |
| [mitral insufficiency due to ruptured chordae tendineae]. | | 2016 | 4857004 |
| [olivocerebellar atrophy predominantly affecting the vermis (clinical and etiopathogenic aspects apropos of 34 cases)]. | | 2011 | 3079273 |
| ultraviolet resonance raman spectroscopy of distamycin complexes with poly(da)-poly(dt) and poly(da-dt): role of h-bonding. | raman spectra are reported for distamycin, excited at 320 nm, in resonance with the first strong absorption band of the chromophore. qualitative band assignments to pyrrole ring and amide modes are made on the basis of frequency shifts observed in d2o. when distamycin is dissolved in dimethyl sulfoxide or dimethylformamide, large (30 cm-1) upshifts are seen for the band assigned to amide i, while amides ii and iii shift down appreciably. similar but smaller shifts are seen when distamycin is bou ... | 2009 | 2765491 |
| a regression approach to the projection of u.s. fertility based on past fertility data. | the method of fertility projection used by the u.s. bureau of the census involves assumptions about the ultimate cohort total fertility rate and the ultimate cohort mean age at childbearing based on recent levels of fertility and women's birth expectations. this paper provides an outline of a general regression approach to fertility projection based on past data which would generate these two ultimate cohort characteristics. the technique is illustrated by using the u.s. single-year age-specific ... | 2009 | 2629113 |
| the three-dimensional similarity between a dimeric antiparallel extended structure and a beta-turn folded form of enkephalin. | the three-dimensional similarity between two fundamental conformations, a dimeric antiparallel extended structure and a type i' beta-turn folded form, of enkephalin was examined by computer graphic and empirical energy calculation methods. by the rotation of tyr and phe side chains, one half of the former structure could mimic the three-dimensional form of the latter without a large loss of conformational energy. this result provides a new idea for considering the conformation of enkephalin suit ... | 2010 | 3030814 |
| fever following orthopedic operations in children. | one hundred fifty-three orthopedic operations in 129 children were analyzed for the significance of postoperative fever (pof) as a predictive factor for possible complications. in 72% of the operations, a temperature of greater than 37 degrees c was recorded. in 63 operations (41%), the temperature was greater than 38 degrees c. sixteen children had positive clinical signs that might explain the fever, and all of them had a temperature of greater than 38 degrees c. duration of operation of great ... | 2014 | 3958164 |
| usefulness of continuous positive airway pressure in differential diagnosis of cardiac from pulmonary cyanosis in newborn infants. | differential diagnosis of cyanosis in the neonate is difficult and cardiac catheterisation may be required for a correct diagnosis. it has been suggested that the response of pao2 to continuous positive airway pressure (cpap) with 100% oxygen may be useful. the purpose of this study was to test further this hypothesis by studying all neonates investigated for cyanosis with a pao2 less than or equal to 50 torr in 0-8 to 1-0 f1o2. arterial blood samples were obtained in an f1o2 of 0-21-0-4 and 0-8 ... | 1973 | 356748 |
| [orthodontic apparatus as a support measure for jaw surgery]. | | 1980 | 294041 |
| [practical relations of orthodontic stomatology with stomatologic disciplines]. | | 1980 | 294039 |
| injection rate: a factor in contrast reactions. | | 2008 | 2390843 |
| expressed emotion in caregivers of the dementing elderly. | this paper presents findings on the association between 'expressed emotion' (ee) and a number of factors previously investigated in relationship to caregivers of the dementing elderly. frequency of critical comments (expressed emotion) was correlated with a number of supporter and dependent characteristics, variables within the relationship between caregivers and their dementing relatives, and help from professionals. the analysis revealed significant correlations between ee and sex of caregiver ... | 2009 | 2789977 |
| development of a single probe for documentation of chimerism following bone marrow transplantation. | although numerous genetic markers are available for studying chimerism after bone marrow transplantation (bmt), there remains a need for a practical and highly informative method that is applicable in the early posttransplantation period. using dna restriction-fragment-length polymorphisms (rflps), we have evaluated the feasibility of developing a single synthetic oligonucleotide probe to study post-bmt chimerism. we have thus tested three candidate probes, termed o-3315-32, o-3315-80, and o-ay- ... | 2010 | 2890295 |
| presidential address: william c. campbell. introduction of president campbell. | | 2012 | 3282045 |
| [the role of plurisensorial evoked potentials in anesthesia, pain and resuscitation]. | | 2014 | 4069386 |