| [use of ethidium for the cytochemical study of chromatin]. | a cytochemical method of chromatin study by means of nuclear staining with ethidium (bromide) is described. dependence of stain binding by chromatin on ethidium concentration, ionic composition and buffer ph value has been analyzed. it is suggested that cells be stained in 2.10(-5) m solution of ethidium in 0.1 m tris-hcl buffer at ph 8.0 during 30 min. the fluorescence of nuclei stained with ethidium under conditions described is shown to reflect changes in physico-chemical properties of chroma ... | 1979 | 92086 |
| acute experimental allergic encephalomyelitis. myelin basic protein-reactive t cells in the circulation and in meningeal infiltrates. | mbp-reactive early t cells were determined simultaneously in the circulation and in inflammatory cells from the meninges of guinea pigs with acute eae. in addition, early and late t cells as well as b cells were estimated in both compartments. within the circulation, early t cells were found to decrease at the onset of clinical signs, and mbp-reactive early t cells were significantly higher than in normals. different changes were found in inflammatory cells from the meninges. in this cell popula ... | 1979 | 92528 |
| asymmetric transcription of the globin genes by escherichia coli rna polymerase in isolated mouse foetal liver chromatin or nuclei [proceedings]. | | 1979 | 92966 |
| studies on the mechanism of vaccinal immunity to marek's disease. | | 1978 | 93038 |
| quantitation of skin bacteria: lethality of the wash solution used to remove bacteria. | a widely used technique for the quantitative removal of bacteria from the skin uses a detergent, triton x-100 (p, t-octylphenoxynonaethoxyethanol), to remove and suspend the bacteria. we determined the half-life for the survival of five common skin bacteria suspended in the solution. the shortest-lived was streptococcus pyogenes with a half-life of 0.9 hours. all of the others (propionibacterium acnes, staphylococcus epidermidis, staphylococcus aureus, and klebsiella pneumoniae) had half-lives o ... | 1979 | 93373 |
| adjuvant effect of a peptidoglycan attached covalently to a synthetic antigen provoking anti-phage antibodies. | the synthetic antigen denoted p2-a--l, comprising the fragment p2 of the coat protein of ms-2 coliphage attached to multichain poly-dl-alanine, served for the immunization of guinea-pigs. immunization was carried out either in phosphate buffered saline (pbs) or in freund's incomplete adjuvant (fia) in the presence or absence of a small molecular weight peptidoglycan prepared from bacillus megaterium, which was checked for its adjuvant effect. the various antisera were assessed by their capacity ... | 1978 | 101440 |
| local antivirals in a herpes simplex stromal keratitis model. | a herpes simplex stromal keratitis rabbit model, which was produced by intrastromal injection of live virus, was used to evaluate the effects of local antivirals on the natural course of the disease. topical trifluridine (trifluorothymidine) and vidarabine monophosphate (adenine arabinoside monophosphate), when given early and frequently, suppressed the disease, indicating that viral replication was important in initiating the disease. however, seven days after the stromal disease had begun to d ... | 1979 | 106813 |
| adjuvant activity of bacterial peptidoglycans. | purified peptidoglycans isolated from various gram negative and gram positive bacteria can substitute for mycobacteria in freund's adjuvant. monomeric subunits possess the same adjuvant activity. this activity seems to be related to the peptidic fraction. | 1975 | 126567 |
| [the protective effect of magnesium-aspartate-procaine cardioplegia on the hypertrophied left ventricle of the mini-pig (author's transl)]. | after induction of left ventricular hypertrophy by supravalvar constriction of the ascending aorta in mini pigs (atp and lactate) were measured under different cardioplegic conditions. in normothermia and plain anoxic arrest atp decrease and lactate increase were significantly slower in hypertrophied myocardium compared to normal myocardium. injection cardioplegia using magnesium-aspartate-procaine at 37 degrees c did not influence the atp decrease and lactate increase in the hypertrophied ventr ... | 1978 | 150067 |
| synthesis and identification of products derived from the metabolism of the carcinostatic 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea by rat liver microsomes. | liver microsomal metabolism of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea in the presence of reduced nicotinamide adenine dinucleotide phosphate and o2 was shown to produce seven metabolites that included the parent urea. a cytochrome p-450-dependent monohydroxylation of the cyclohexyl ring occurred in 3 positions, cis-3, trans-3, and cis-4, and on the methyl group to form a trans-4-hydroxymethyl derivative. in addition, monohydroxylation of the 2-chloroethyl carbon attached to ... | 1979 | 427763 |
| [method of studying the allergenic activity of chemical substances in connection with setting norms for them in the water of reservoirs]. | | 1979 | 520845 |
| effects of neonatal undernutrition on small intestinal dipeptidase(s) activity. | | 1979 | 546746 |
| adaptation of contractile proteins in human heart and skeletal muscles. | sarcomeric muscles including the myocardium respond to increased workload with adaptation by differential gene expression and without cell division. this is characteristic for postmitotic tissues. we showed that a short period of high intensity endurance training induces a shift from fast myosin heavy (hc) and light (lc) chain isoforms towards the slow variety within histochemically typed fibres of human vastus lateralis muscle. in an intermediary state of transition both varieties of isoforms a ... | 1989 | 2757604 |
| the middle t proteins of high and low tumor strains of polyomavirus function equivalently in tumor induction. | the pta strain of polyomavirus induces a variety of epithelial as well as mesenchymal tumors at high frequencies, while the ra strain induces only rare mesenchymal tumors following inoculation into newborn mice. dna sequence analysis has revealed one amino acid difference between the middle t (mt) proteins encoded by these two virus strains. to test for possible biological differences between the mt proteins we constructed a recombinant virus carrying mt-coding sequences of ra on a pta backgroun ... | 1988 | 2849243 |
| the relaxant and spasmogenic effects of some xanthine derivatives acting on guinea-pig isolated trachealis muscle. | 1. caffeine (10 mm)-induced relaxation of guinea-pig isolated trachealis was attenuated and converted to a small spasmogenic response on cooling to 22 degrees c. the relaxant response was restored on rewarming to 37 degrees c and was abolished by indomethacin (2.8 microm). cooling to 22 degrees c in the presence of indomethacin revealed spasmogenic responses to caffeine which were abolished on rewarming to 37 degrees c. 2. trachealis treated with indomethacin (2.8 microm) was repeatedly dosed wi ... | 1988 | 3145087 |
| the genes encoding major surface proteins of borrelia burgdorferi are located on a plasmid. | | 1988 | 3190089 |
| risk for the acquired immunodeficiency syndrome among thrombocytopenic and nonthrombocytopenic homosexual men seropositive for the human immunodeficiency virus. | a group of 44 homosexual patients with immune thrombocytopenia and serologic evidence of infection with the human immunodeficiency virus (hiv) was observed for a total of 844 person-months. the risk of developing the acquired immunodeficiency syndrome (aids), an actuarial incidence of 36.5% in 37 months, was no different than that reported for seropositive homosexual men from new york who are nonthrombocytopenic and asymptomatic. a statistical analysis comparing the hazard function with a consta ... | 1987 | 3468820 |
| changes in the tooth enamel of early paleocene mammals allowing increased diet diversity. | hunter-schreger bands (hsb) are seen in teeth that are composed of crossed sets of enamel prisms. they are present in the teeth of man and many other mammals, but absent in most insectivores and multituberculates. it has been suggested that the presence of hsb makes the tooth enamel less likely to split and is associated with chewing ability. we have traced the occurrence of hsb back to the arctonic condylarths of the early palaeocene (puercan) age; this must be close to the first appearance of ... | 1987 | 3600790 |
| fate of uncrossed retinal projections following early or late prenatal monocular enucleation in the mouse. | in mammals binocular vision is made possible by the existence in the temporal retina of ipsilaterally projecting ganglion cells (igcs) (with axons that do not cross the brain midline and join optic fibers from the opposite eye). to learn whether early interactions between fibers of each eye play a role in generating a mixed ipsi + contralateral projection pattern, we studied with horseradish peroxidase the origin of uncrossed retinal projections in mice that developed after one eye was destroyed ... | 1987 | 3819012 |
| how to do the right thing at the right time. | | 2005 | 1065124 |
| application of environmental management principles in the program for eradication of aedes (stegomyia) aegypti (linneus, 1762) in the republic of cuba, 1984. | | 2010 | 3768599 |
| the identification of f actin of the pollen tube and protoplast of amaryllis belladonna. | | 1974 | 4609784 |
| [cholesterol levels in a population of 7,400 men from 8 industrial plants in wrocław]. | | 2013 | 4070664 |
| [the mechanism of induction of ovulation by bromocriptine in euprolactinemic anovulation--the role of occult hyperprolactinemia in anovulation]. | it has been well documented that ovulation was induced by bromocriptine treatment in euprolactinemic anovulation. the present study has been carried out to clarify the underlying mechanism. 28 patients with euprolactinemia (prl less than 25 ng/ml) were treated with a 5 mg daily administration of bromocriptine. ovulation was induced in 13 cases, which were determined by their bbt charts. in the ovulated cases, prl secreting capacities were increased, determined by trh administration. on the other ... | 2013 | 3996685 |
| [the value of computed tomography in the study of torsion of the lower limbs]. | the ct features of 21 patients with various lower limbs torsional aberrations are presented. in each of them ct measurements of the different torsional angles of the entire limb are carried out using an accurate method. ct proves very useful for a whole and comparative torsional study of lower limbs. | 2013 | 4070699 |
| evaluation of the effects of vitamin c on ozone-induced bronchoconstriction in normal subjects. | | 2012 | 3304064 |
| the centenary of the sri lanka medical association. | | 2012 | 3333478 |
| torquing in class: an interesting twist for orthodontists. | a method of measuring the amount of slack inherent in the system of edgewise brackets and archwires is presented, and some related problems concerning the use of turrets discussed. | 2012 | 3475126 |
| [updated highlights]. | | 2012 | 3745829 |
| [updated highlights]. | | 2012 | 3745829 |
| anterior spinal tuberculosis: paraplegia following laminectomy. | | 2010 | 2802487 |
| serum amino acids in hepatic encephalopathy--effects of branched chain amino acid infusion on serum aminogram. | encephalopathic patients with cirrhosis of the liver consistently showed elevated levels of the aromatic amino acids, phenylalanine, tyrosine and free tryptophan as well as methionine in serum, whereas levels of the branched chain amino acids, valine, leucine and isoleucine, were depressed. comatose patients with fulminant hepatitis had markedly elevated levels of all amino acids, the results being greatly different from those of cirrhotic patients. molar ratios of (valine + leucine + isoleucine ... | 2004 | 525213 |
| editorial: dietary prudence. | | 2015 | 4408191 |
| the a-b-o blood groups in a baboon colony in france. | | 2016 | 4989307 |
| [role of a medical academy in the training of medical cadres]. | | 2015 | 4607866 |
| nutrition education of chiropractic students: a survey of colleges recognized by the council on chiropractic education. | concern has been expressed that the public is subject to nutritional misinformation. examination of nutrition designated units in nine chiropractic colleges enjoying accreditation or candidate status according to the council on chiropractic education suggests that these colleges are not a source of such misinformation. | 2008 | 2394948 |
| laboratory correlates of adoptive immunotherapy with recombinant interleukin-2 and lymphokine-activated killer cells in humans. | adoptive immunotherapy with interleukin 2 (il-2) and lymphokine-activated killer (lak) cells (il-2/lak) is a technically demanding cancer therapy dependent upon large scale isolation and culture of lymphocytes. an important question is whether this technology can be accomplished routinely outside of highly specialized centers. in addition, no systematic examination of laboratory correlates of il-2/lak therapy in humans has been reported to date. the objectives of this report are to address two i ... | 2009 | 3260537 |
| adenocarcinoma arising at the ileocutaneous junction occurring after proctocolectomy for ulcerative colitis. | | 2012 | 3708290 |
| adenocarcinoma arising at the ileocutaneous junction occurring after proctocolectomy for ulcerative colitis. | | 2012 | 3708290 |
| psychiatric treatment in gaol. | | 2013 | 3869013 |
| [indices of the activity of the pathological process in chronic pneumonias]. | | 2001 | 92858 |
| [diagnosis of the unilateral stapedo-vestibular ankylosis syndrome]. | | 2002 | 123937 |
| psychiatric treatment in gaol. | | 2013 | 3869013 |
| fire safe cigarettes. an update. | | 2009 | 2708422 |
| variant angina aggravated by aspirin. | | 2001 | 92734 |
| enhanced response to con a and production of tcgf by lymphocytes of obese strain (os) chickens with spontaneous autoimmune thyroiditis. | the mitogenic response to con a and the production of t cell growth factor or interleukin 2 (il 2) by splenic and peripheral blood lymphocytes of obese strain (os) chickens with spontaneous autoimmune thyroiditis have been investigated. by using an optimized method with con a-coated chicken erythrocytes (mrc), lymphocytes of os chickens were found to exhibit significantly elevated mitogenic responses as compared with cells from either normal white leghorn chickens (nwl) or animals of the cornell ... | 1985 | 3917478 |