interaction of human polymorphonuclear leukocyte elastase with human igm in vitro production of an fabmu-like fragment. 197991095
interactions of guinea pig eye tissue to fluorescein isothiocyanate labelled homologous serum and anti-polymer sera. 197891473
[use of ethidium for the cytochemical study of chromatin].a cytochemical method of chromatin study by means of nuclear staining with ethidium (bromide) is described. dependence of stain binding by chromatin on ethidium concentration, ionic composition and buffer ph value has been analyzed. it is suggested that cells be stained in 2.10(-5) m solution of ethidium in 0.1 m tris-hcl buffer at ph 8.0 during 30 min. the fluorescence of nuclei stained with ethidium under conditions described is shown to reflect changes in physico-chemical properties of chroma ...197992086
acute experimental allergic encephalomyelitis. myelin basic protein-reactive t cells in the circulation and in meningeal infiltrates.mbp-reactive early t cells were determined simultaneously in the circulation and in inflammatory cells from the meninges of guinea pigs with acute eae. in addition, early and late t cells as well as b cells were estimated in both compartments. within the circulation, early t cells were found to decrease at the onset of clinical signs, and mbp-reactive early t cells were significantly higher than in normals. different changes were found in inflammatory cells from the meninges. in this cell popula ...197992528
asymmetric transcription of the globin genes by escherichia coli rna polymerase in isolated mouse foetal liver chromatin or nuclei [proceedings]. 197992966
immunoperoxidase labelling of alpha 1-fetoprotein (afp) in normal and regenerating livers of a low and a high afp producing mouse strain. 197993094
quantitation of skin bacteria: lethality of the wash solution used to remove bacteria.a widely used technique for the quantitative removal of bacteria from the skin uses a detergent, triton x-100 (p, t-octylphenoxynonaethoxyethanol), to remove and suspend the bacteria. we determined the half-life for the survival of five common skin bacteria suspended in the solution. the shortest-lived was streptococcus pyogenes with a half-life of 0.9 hours. all of the others (propionibacterium acnes, staphylococcus epidermidis, staphylococcus aureus, and klebsiella pneumoniae) had half-lives o ...197993373
adjuvant effect of a peptidoglycan attached covalently to a synthetic antigen provoking anti-phage antibodies.the synthetic antigen denoted p2-a--l, comprising the fragment p2 of the coat protein of ms-2 coliphage attached to multichain poly-dl-alanine, served for the immunization of guinea-pigs. immunization was carried out either in phosphate buffered saline (pbs) or in freund's incomplete adjuvant (fia) in the presence or absence of a small molecular weight peptidoglycan prepared from bacillus megaterium, which was checked for its adjuvant effect. the various antisera were assessed by their capacity ...1978101440
beta-galactosidase and selective neutrality.three hypotheses to explain the amino acid composition of proteins are inconsistent (p congruent to 10(-9) with the experimental data for beta-galactosidase from escherichia coli. the exceptional length of this protein, 1021 residues, permits rigorous tests of these hypotheses without complication from statistical artifacts. either this protein is not at compositional equilibrium, which is unlikely from knowledge about other proteins, or the evolution of this protein and its coding gene have not ...1979106468
[age and season related dynamics of vitamin e levels in the serum of young cattle from birth to the age of 22 months].the dynamics of serum vitamin e levels in heifers was followed for 22 months. we found that calves were born with a very low, almost nil, content of this vitamin (on an average 0.029 mg%) as a result of the limited diaplacental transfer from the mother to the fetus. in the following period of extrauterine life and growing up of the young cattle conspicuous age dynamics was recorded which is, however, linked or affected by the seasons. colostral nutrition which is reflected in the increasing seru ...1979106508
local antivirals in a herpes simplex stromal keratitis model.a herpes simplex stromal keratitis rabbit model, which was produced by intrastromal injection of live virus, was used to evaluate the effects of local antivirals on the natural course of the disease. topical trifluridine (trifluorothymidine) and vidarabine monophosphate (adenine arabinoside monophosphate), when given early and frequently, suppressed the disease, indicating that viral replication was important in initiating the disease. however, seven days after the stromal disease had begun to d ...1979106813
physiological and genetic modifications of the expression of the yeast mitochondrial adenosine triphosphatase inhibitor.1. the oligomycin-sensitive atpase activity of submitochondrial particles of the glycerol-grown "petite-negative" yeast: schizosaccharomyces pombe is markedly stimulated by incubation at 40 degrees c and by trypsin activations are treatment. both increased in triton-x 100 extracts of the submitochondrial particles. 2. a trypsin-sensitive inhibitory factor of mitochondrial atpase with properties similar to that of beef heart has been extracted and purified from glycerol-grown and glucose-grown s. ...1975123768
biological properties of the peptidoglycan.this review deals with those biological activities of peptidoglycan that are not directly analogous to the properties of gram-negative bacterial endotoxin. the report is divided into 3 major parts: 1. a survey of peptidoglycan activities such as the induction of inflammatory skin reactions, lesion-enhancing activity (virulence factor), inhibition of phagocytosis of bacteria, inhibition of cell migration, cytotoxicity to mammalian cells, potentiation of the humoral and cellular immune response (a ...1975126557
[the protective effect of magnesium-aspartate-procaine cardioplegia on the hypertrophied left ventricle of the mini-pig (author's transl)].after induction of left ventricular hypertrophy by supravalvar constriction of the ascending aorta in mini pigs (atp and lactate) were measured under different cardioplegic conditions. in normothermia and plain anoxic arrest atp decrease and lactate increase were significantly slower in hypertrophied myocardium compared to normal myocardium. injection cardioplegia using magnesium-aspartate-procaine at 37 degrees c did not influence the atp decrease and lactate increase in the hypertrophied ventr ...1978150067
scanning electron microscopy of interaction of peripheral blood lymphocytes from colonic cancer patients with human colonic cancer-derived cells; p-4788.peripheral blood lymphocytes and the various lymphocyte fractions from patients with cancer of the colon were cultivated with target cells (p-4788) derived from the colon cancer. changes in the surface ultrastructure during tumor cell destruction were studied by scanning electron microscopy (sem). p-4788 cells adhering to the coverslip showed various surface activity. the surfaces of some cells were relatively flat; others were smooth or had fine granules. still other cells were villous, round o ...1979161468
catabolite inactivation of phosphoenolpyruvate carboxykinase in spheroplasts from saccharomyces cerevisiae.catabolite inactivation of phosphoenolpyruvate carboxykinase was studied in yeast spheroplasts using 0.9 m mannitol or 0.6 m potassium chloride as the osmotic support. in the presence of potassium chloride the rate of catabolite inactivation was nearly the same as that occurring in intact yeast cells under different conditions of incubation. however, in the presence of mannitol, catabolite inactivation in spheroplasts was prevented. the mannitol inhibition of catabolite inactivation was released ...1979383159
thallium-201 accumulation by epidermoid inclusion elderly male undergoing re-evaluation for coronary artery disease demonstrated an extra-cardiac focus of 201tl accumulation during the performance of a planar myocardial perfusion scan. this corresponded to a subcutaneous lesion of the left posterior thorax found on a concurrent computerized axial tomographic (cat) scan and upon surgical excision proved to be an "epidermoid inclusion cyst." a follow-up nuclear scan failed to reveal any residual extracardiac tracer localization. confusing this ...19921403158
detection of mycobacterium tuberculosis antigen 5 in cerebrospinal fluid by inhibition elisa and its diagnostic potential in tuberculous meningitis.inhibition elisa was used to quantitate mycobacterium tuberculosis antigen 5 in cerebrospinal fluid (csf) specimens of 40 patients with a clinical diagnosis of tuberculous meningitis. in all 10 culture-proven patients, the assay was positive; in 30 culture-negative patients, the assay yielded positive results for 21. csf antigen 5 concentrations ranged from 9 to 82 ng/ml (mean +/- sd, 45.5 +/- 6.2). in 40 patients with nontuberculous neurologic diseases, mean concentration was 1.45 ng/ml. thus, ...19911899876
protective effect of inactivated pasteurella haemolytica bacterin challenged in bovine herpesvirus-1 experimentally infected calves.formalin-inactivated and sonicated pasteurella haemolytica bacterins were prepared from 1 h cultures of bacterial pellets in rpmi-1640 medium containing 7% fetal calf serum. the bacterial pellets were obtained from logarithmic phase growth of the organism by centrifugation. the protective effect of the vaccine was evaluated in 43 specific-pathogen-free hereford crossbred calves and yearlings in three experiments. cattle were either single vaccinated or boosted via three routes; intratracheally ( ...19902168606
aids--an interview with ole morten nygaard who is hiv positive. interview by marie farrell and richard wells. 19902394895
substance p and neurotensin: their roles in the regulation of anterior pituitary function. 19862423025
temporal study of staphylococcal species on the skin of human subjects in isolation and clonal analysis of staphylococcus capitis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.the staphylococcal skin floras of an isolated group of subjects were studied for 1 year. a wide variation in isolation patterns was found for different species. staphylococcus intermedius, previously thought to be of veterinary origin, was found to be part of the resident flora of some subjects, and this may indicate a wider role for it in clinical infection. sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sds-page) analysis of s. capitis isolates indicated persistent skin colonizatio ...19892687313
opening remarks of president fernando e. agrait on the occasion of the 50th anniversary of the cayo santiago macaque colony. 19892780954
a molecular strategy for the study of bacterial invasion.bacterial populations are often clonal, and even within a bacterial species, the frequency of gene exchange and recombination is quite low. consequently, mobile genetic elements--plasmids, bacteriophages, and transposons--have been the central factors in the evolution of pathogenic traits. one central feature of pathogenicity, the capacity to enter epithelial cells, is encoded by the bacterial chromosome of yersinia pseudotuberculosis but by plasmid genes in enteroinvasive escherichia coli. a si ...19872825322
[human chorionic prealbumin: its identification, physicochemical properties and detection in the blood serum in trophoblastic disease].human chorionic prealbumin (hcpa) was immunochemically identified and isolated in pure form from immature placenta, particularly, from chorion. comparative immunodiffusion analysis shows that hcpa differs from the known placenta-specific proteins. hcpa is a glycoprotein with mw about 100 kd determined by gel-filtration and 45 kd by sds polyacrylamide gel electrophoresis. by immunodiffusion hcpa was not found in fetal and adult tissues and in biological fluids. hcpa was discovered in patients wit ...19882848598
suppression of sv40-promoted gene expression by differentiation of preadipose cells.when a plasmid bearing the chloramphenicol acetyltransferase (cat) gene under the control of an sv40 early promoter is introduced into preadipose or adipose cells of line 3t3-f442a, the promoter directs high levels of transient expression of cat. however, when the plasmid is introduced into preadipose cells and the cells are then allowed to differentiate into adipose cells, the expression of the cat gene is suppressed. in this process, the plasmid is not changed detectably in amount, topology, o ...19882849579
a murine monoclonal antibody raised against human non-small cell carcinoma of the lung.murine monoclonal antibodies (mabs) reactive with human non-small cell carcinoma of the lung (nsccl) were produced following immunization with a membrane preparation of calu-3, a human adenocarcinoma of the lung cell line grown in nude mice. positive hybrids unreactive with normal liver membranes and human peripheral white blood cells were selected for further testing. one mab (rs5-4h6) recognized an antigen expressed in a variety of lung and other carcinoma cell lines as detected by flow cytome ...19882853133
purification of carp growth hormone and cloning of the complementary dna.the growth hormone (gh) was isolated and purified from common carp (cyprinus carpio) pituitary glands by salt precipitation and hplc on reverse-phase c18 columns. the carp gh cdna was synthesized and cloned in escherichia coli using ecori linkers and pbr322 as vector. the positive clones were selected and sequenced. the full-length carp gh cdna contains 1187 nucleotide basepairs with an open reading frame coding for the precursor form carp gh of 210 amino-acid residues. the partial amino-acid se ...19892920175
diabetic embryopathy and fuel-mediated organ teratogenesis: lessons from animal models.the growing recognition that faulty maternal metabolism during early organogenesis may be implicated in the increased incidence of birth defects in pregnancies complicated by diabetes has prompted worldwide efforts to institute improved preconceptional metabolic regulation. however, the failure to identify the periods of greatest risk for diabetic embryopathy, the mediating teratogen(s), and the underlying mechanisms have complicated attempts to establish precise therapeutic guidelines and targe ...19883053387
effect of polynucleotides on aminoacyl transfer ribonucleic acid synthetases. 3. inhibition of glutamyl transfer ribonucleic acid synthetase by natural polynucleotides. 19684299520
experimental allergic neuritis in the dog and its comparison with the naturally occurring disease; coonhound paralysis. 19744451040
cross resistance of escherichia coli b ribosomes to inhibition of the puromycin reaction by erythromycin, spiramycin and chloramphenicol. 19684870247
cerebral perfusion pressure: a hemodynamic mechanism of mannitol and the postmannitol hemogram.sixteen patients each received infusions of 1 g of mannitol per kg over 5 to 10 minutes, and serial determinations of intracranial pressure (icp), systemic arterial blood pressure (sabp), central venous pressure, cerebral perfusion pressure (cpp), hematocrit, hemoglobin, serum na+, k+, osmolarity, and fluid balance were carried out for 4 hours. urine output was replaced volume for volume with 5% dextrose in 0.45% nacl solution. we tested the hypothesis that patients with high (greater than or eq ...20103116451
[the action of pesticides on the genitalia and reproductive function]. 20092662799
lateral mobility of proteins and lipids in the red cell membrane and the activation of adenylate cyclase by beta-adrenergic receptors.models of beta-adrenergic signal transduction in red blood cell membranes frequently assume that at least one of the membrane-bound components is laterally mobile and distributes the hormonal signal in the membrane plane. however, direct measurements reveal that protein lateral mobility in the red cell membrane is severely restricted. furthermore, the spectrin-actin compartmentalizes the cytoplasmic face of the red cell membrane into a regular array of small elementary areas. these consideration ...20102839357
[impressions of a study trip to japan]. 20154495220
the reticuloendothelial system and rheumatoid arthritis. 199990988
minimal incision techniques for digital deformities.we have presented basic minimal incision approaches to the more common digital deformities. we feel that with proper evaluation of the deformity and the patient, minimal incision surgery techniques give excellent long-term results with several advantages. these advantages include: less discomfort due to less surgical dissection. less need for internal fixation by careful use of compression dressings in the immediate postoperative period along with early ambulation. less disability. compression d ...20102937517
lipid and lipoprotein effects on endothelial eicosanoid important function of endothelium is to release pgi2, a prostaglandin produced from arachidonic acid that prevents platelet aggregation and causes arterial relaxation. small amounts of other eicosanoids also are produced, but their role in endothelial function has not been elucidated. much of the arachidonic acid present in the endothelium is obtained preformed from the plasma, either as ffa or from lipoproteins. arachidonic acid is efficiently incorporated into endothelial lipids even when o ...20113061005
how to do the right thing at the right time. 20051065124
psychodynamics of the young handicapped person.psychodynamics of personality and ego development are related to motor development. the body image concept, important for normal psychologic performance is often impaired by somatic or cerebral defects. adolescents are particularly depressed by loss of self-esteem and thwarting of future career goals. sexuality is an important consideration for the handicapped.2002127532
effects of glycerol treatment and maintained depolarization on charge movement in skeletal muscle.1. voltage-clamp experiments were carried out using the techniques described in the preceding paper. 2. in one series of experiments an attempt was made to disrupt the t-system with glycerol treatment. muscles were soaked in ringer + 400 mm glycerol for 1 hr at room temperature, transferred to ringer + 5 mm calcium + 5 mm magnesium for 20-30 min, and then cooled to around 2 degrees c and placed in an isosmotic test solution containing tetrodotoxin for electrical measurements. 3. the density of c ...20051082507
the nasal mast cell and rhinitis. 20071913276
distinct h-2-linked ir genes control both antibody and t cell responses to different determinants on the same antigen, myoglobin.the murine antibody and t lymphocyte proliferative responses to sperm whale myoglobin (mb) were found to be under control of two distinct h-2-linked immune response (ir) genes (ir-mb-1, mapping in the i-a subregion, and ir-mb-2, mapping in i-c). h-2(d) mice (b10.d2 and dba/2), with both genes, were high responders to mb and its fragments for both antibody secretion and t cell proliferation, while h-2(b) (b10) and h-2(k) ( mice were low responders. strains with only ir-mb-2 [b10.a and b10. ...199991172
the efficient use of the hygienist: how is the public best served? 20123475470
chondrodysplasia punctata: case report with dental findings. 20102942843
[nursing--a woman's job!]. 20061489626
the oxidation of acetoin to co 2 in intact animals and in liver mince preparation. 19725029485
pharmacological evaluation of medicinal plants from western samoa. 19734714114
schnyder's dystrophy. progression and the first long-term cohort study of schnyder's corneal dystrophy the authors examined affected and unaffected members of two unrelated families in 1975 and 1976 respectively, and again in 1984. they identified carriers, catalogued changes in the diffuse and crystalline corneal opacities which characterize this dystrophy and analysed the patient's lipid metabolism. corneal opacities never regressed. progression was more frequent in diffuse than in crystalline opacities. both crystalline and di ...20123486394
ultrastructure of muscle spindles in c57bl/6j dy2j/dy2j dystrophic mice.the sensory organs of skeletal muscles, the muscle spindles, were examined using electron microscopy in dy2j/dy2j dystrophic mice. despite widespread damage to the extrafusal (skeletomotor) fibres the intrafusal (spindle) fibres appeared normal and seemed resistant to the aetiological factors for murine dystrophy.2003154410
naproxen prevention of heterotopic ossification after hip arthroplasty. a prospective control study of 55 patients.the effect of naproxen on heterotopic ossification after total hip replacement was studied in a randomized, double-blind trial. twenty-eight patients received 250 mg naproxen thrice daily for 4 weeks postoperatively starting on the morning of the operation while 27 control patients received a placebo. three months after the operation, 13 patients in the control group had heterotopic ossification compared with 4 patients in the group that received naproxen; and after 1 year, the figures were 15 a ...20071904183
[clinical and treatment characteristics of tertian malaria in viral hepatitis a]. 20113195076
nifedipine reduces the incidence of myocardial infarction and transient ischemia in patients undergoing coronary bypass grafting.a randomized study was performed on 104 patients undergoing elective coronary artery bypass grafting to examine whether the infusion of nifedipine (n = 53) reduces the incidence of perioperative myocardial ischemia and necrosis in the early postoperative period. continuous hemodynamic and three-channel holter monitoring was performed for 24 hours and serial assessment of serum enzymes and 12-lead electrocardiography were performed for 36 hours postoperatively. nifedipine (minimum dose, 10 microg ...20061899365
acute pancreatitis--a challenge to gastroenterologists and surgeons. 20061855778
acute pancreatitis--a challenge to gastroenterologists and surgeons. 20061855778
the leukaemia research fund data collection survey: the incidence and geographical distribution of acute myeloid leukemia.this paper reports on the 2,362 cases of acute myeloid leukemia (aml) accumulated by the leukaemia research fund data collection survey between january 1, 1984, and june 30, 1988 providing the recent geographical distribution and descriptive epidemiology of the aml group of conditions. statistical approaches to this data set are described. the study shows sex differences in distribution for those aged under 55 years compared to older age groups, with variable male: female incidence in different ...20072586181
cytogenetic engineering in vivo: restoration of biologic complement activity to c5-deficient mice by intravenous inoculation of hybrid cells.splenic macrophages were identified as at least one source of c5 elaboration in normal mice. hybrid cells were formed from splenic macrophages from c5-deficient mice and either kidney cells from mice with normal amounts of c5 or chicken erythrocytes. these hybrids elaborated c5 in vitro. c5-deficient mice inoculated with these hybrid cells developed, in their serum, antigenically active mouse c5, as well as both hemolytic and biologic complement activity. these studies demonstrate the feasibilit ...19734131744
botulinum toxin a-induced protective ptosis in corneal disease.botulinum toxin a produces a temporary, flaccid ptosis when injected into the levator palpebrae superioris muscle. the resulting protective ptosis was used to aid healing in 21 cases of indolent ulceration, and, prophylactically, in 4 cases of neuroparalytic keratitis. of the indolent ulcers, 90% healed completely. in all but one case, the cornea was covered completely by the lid and complete ptosis was produced in 75% of cases in an average of 3.6 days, lasting for 16 days on average before rec ...20113050691
confronting membranes at the ruffled border in osteoclasts of cultured fetal parietal bone. 20133837812
soil water samplers in ion balance studies on acidic forest soils. 20133697532
influence of stimulus-response translations on response programming: examining the relationship of arm, direction, and extent of movement. 20143953307
the influence of sex-specific brain differentiation and of postpuberal sex hormone levels on the development of sex-specific differences of body weights as well as triglyceride, high-density-lipoprotein-cholesterol and total cholesterol serum levels in rats.the effects of perinatal sexual differentiation of the brain and of postpuberal sex hormone levels on the development of sex-specific differences in body weight as well as triglyceride (tg), high-density-lipoprotein-cholesterol (hdl-chol) and total cholesterol were investigated. significant differences in body weight of male and female rats are attributed to the influence of different androgen levels during the perinatal period as well as to the influence of different postpuberal estrogen (e) an ...19854054223
escherichia coli diarrhoea. 19853912432
fate of uncrossed retinal projections following early or late prenatal monocular enucleation in the mammals binocular vision is made possible by the existence in the temporal retina of ipsilaterally projecting ganglion cells (igcs) (with axons that do not cross the brain midline and join optic fibers from the opposite eye). to learn whether early interactions between fibers of each eye play a role in generating a mixed ipsi + contralateral projection pattern, we studied with horseradish peroxidase the origin of uncrossed retinal projections in mice that developed after one eye was destroyed ...19873819012
studies on the methods for the determination of phosphorylation sites in highly phosphorylated peptides or proteins: phosphorylation sites of hen egg white riboflavin binding determine the phosphate binding sites in hen egg white riboflavin binding protein (rbp), a highly phosphorylated peptide, which consisted of 23 amino acid residues including eight phosphoserines, was isolated from the tryptic digest of reduced and carboxymethylated rbp. the conditions of the beta-elimination-addition reaction to convert phosphoserine residues in the peptide to cysteic acids, s-methylcysteines, alanines, and beta-methylaminoalanines (dl-alpha-amino-beta-methylamino propionic a ...19863818573
differential expression of members of the napin storage protein gene family during embryogenesis in brassica napus.s1 nuclease analysis and sub-family-specific oligonucleotide probes were used to characterize the expression during embryogenesis of the napin storage protein gene family of brassica napus (oilseed rape). the expression of one sub-class represented by the napin gene gna peaks and declines earlier than the other members of the family. this sub-class was highly expressed representing ca. 20% of napin mrna at 26 days after anthesis.20071932683
antihypertensive therapy and the concept of total cardiovascular protection.drug-induced reduction of elevated blood pressure decreases cardiovascular mortality and morbidity in patients with moderate and severe hypertension. furthermore, antihypertensive drug studies in mild hypertensive subjects (diastolic blood pressure 90 to 104 mm hg) have shown protection against stroke, left ventricular hypertrophy, congestive heart failure and progression of renal damage, as well as improved patient longevity. the hypertension detection and follow-up program trial, recently carr ...20102889351
cerebral lesions in early prematurity: eeg prognostic value in the neonatal period.the new radiological technics show the incidence of intraventricular hemorrhage (ivh), intraparenchymal hemorrhage (iph), or of porencephaly (pl), in the neonatal period. discrepancies between the initial extent of lesions and the outcome have been observed. we tried to appreciate the eeg value in infants having had such lesions during the first month of life. we studied serial eegs and neuroradiological exams in 34 babies: with ivh (group i, 17 cases), with iph and/or pl (group ii, 17 cases). t ...20123434715
atrial septectomy in patients with d-transposition of the great arteries, ventricular septal defect, and severe pulmonary vascular obstructive disease. 20144135743
the effect of long-term administration of aspirin and sodium saccharin on the rat a study primarily designed to evaluate the inhibitory effects of aspirin on n-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide (fanft)-initiated and saccharin-promoted bladder carcinogenesis, significant renal lesions were observed. thus, administration in the diet of aspirin and sodium saccharin to f344 male rats for 68 weeks resulted in significant lesions of the renal papilla. in contrast to the bladder, aspirin enhanced the frequency and severity of the proliferative action of sodium saccharin ...19863764937
dapsone and severe hypoalbuminaemia. 199991005
sexual attitudes as correlates of sexual details in human figure drawing.the hypothesis that sexual attitudes, as measured by the sexual opinion survey, are related to the explicitness with which nude figures are drawn was examined. the presence or absence of various sexual and nonsexual anatomical features, as well as length and width measurements, were assessed in the drawing of nudes by 17 male and 23 female undergraduates. individuals with relatively positive sexual attitudes (erotophiles), as compared with individuals with relatively negative attitudes (erotopho ...19883282490
arachidonic acid, prostaglandin e2 and f2 alpha inhibit leucine degradation in chick skeletal muscle.arachidonic acid (5 microm), prostaglandin e2 (0.28 microm) and f2 alpha (14 microm) inhibited (p less than 0.01) the rates of net leucine transamination, leucine oxidative decarboxylation and total co2 production from leucine in extensor digitorum communis muscles from fed ten-day-old chicks. indomethacin (50 microm) markedly inhibited (p less than 0.01) the rate of pge2 production in the presence of 5 microm arachidonic acid and prevented the inhibition of leucine degradation by arachidonic ac ...19883130060
hypocapnia and hypercapnia in the dog: effects on myocardial blood-flow and haemodynamics during beta- and combined alpha- and beta-adrenoceptor blockade.we have recently demonstrated an increase in myocardial blood-flow (mbf) during systemic hypercapnia independent of myocardial oxygen consumption. during hypocapnia no significant decrease of mbf was observed; however, a significant increase of myocardial oxygen extraction resulted. the present study was undertaken to examine whether these effects were caused by changes in the sympathoadrenal activity. during beta-adrenoceptor blockade and combined alpha- and beta-blockade the effects of hypocap ...19873028703
ulnar ray a/hypoplasia: evidence for a developmental field defect on the basis of genetic heterogeneity. report of three brazilian families.we report on five brazilian patients from three unrelated families with congenital anomalies of the upper limbs. ulnar aplasia/hypoplasia was the main reason for examining these patients. evidence for existence of an ulnar developmental field is based on genetic heterogeneity. clinical and genetic aspects of the ulnar ray defects are discussed.20113146291
the middle t proteins of high and low tumor strains of polyomavirus function equivalently in tumor induction.the pta strain of polyomavirus induces a variety of epithelial as well as mesenchymal tumors at high frequencies, while the ra strain induces only rare mesenchymal tumors following inoculation into newborn mice. dna sequence analysis has revealed one amino acid difference between the middle t (mt) proteins encoded by these two virus strains. to test for possible biological differences between the mt proteins we constructed a recombinant virus carrying mt-coding sequences of ra on a pta backgroun ...19882849243
physicochemical and biological studies on the metal-induced conformational change in troponin a. implication of carboxyl groups in the binding of calcium ion. 20144270462
[peculiarities of vocabulary used at the auschwitz camp hospital]. 20154553384
an acyclovir-resistant strain of herpes simplex virus type 2 which is highly virulent for mice.herpes simplex virus type 2 (hsv-2), strain ys-4 c-1, isolated by plaque cloning from a clinical isolate was found to be resistant to acyclovir (acv; acycloguanosine) in vitro. it was sensitive to phosphonoacetic acid and 9-beta-d-arabinofuranosyladenine. thymidine kinase (tk) activity of ys-4 c-1 was less than 1% of that of other strains from the same clinical source. however, thymidine plaque autoradiography showed that ys-4 c-1 was not completely deficient in tk activity. ys-4 c-1 showed high ...19882845890
mk-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys.the behavioral effects of mk-801 [(+)-5-methyl-10,11-dihydroxy-5h-dibenzo(a,d)cyclohepten-5,10-imin e], a proposed noncompetitive n-methyl-d-aspartate (nmda) antagonist, were compared to those of phencyclidine (pcp). in pigeons, mk-801 produced pcp-like catalepsy (i.e., loss of righting without eye closure and without muscle relaxation) and pcp-like discriminative stimulus effects. in rats, mk-801 produced pcp-like behavior (i.e., locomotion, sniffing, swaying and falling). in rhesus monkeys, li ...19882838610
adaptation of contractile proteins in human heart and skeletal muscles.sarcomeric muscles including the myocardium respond to increased workload with adaptation by differential gene expression and without cell division. this is characteristic for postmitotic tissues. we showed that a short period of high intensity endurance training induces a shift from fast myosin heavy (hc) and light (lc) chain isoforms towards the slow variety within histochemically typed fibres of human vastus lateralis muscle. in an intermediary state of transition both varieties of isoforms a ...19892757604
spontaneous bacterial peritonitis in a healthy male caused by streptococcus viridans. 19911913382
localization and quantification of nonapeptide binding sites in the kidney of xenopus laevis: evidence for the existence of two different nonapeptide receptors.the distribution and properties of nonapeptide binding sites in the kidney of the anuran xenopus laevis were investigated using quantitative in vitro autoradiography. the binding studies were performed with [3h]arginine vasopressin (avp) as ligand because [125i]arginine vasotocin (avt) lacks biological activity. specific binding sites for [3h]avp are located in the glomeruli of the kidney. [3h]avp binding results in a steady state of association and dissociation between ligand and binding sites. ...19921563620
reproduction and teratology studies of zinc pyrithione administered orally or topically to rats and rabbits. 1979546699
a dental service for children suffering from cardiac disease. 1975123751
studies on the mechanism of vaccinal immunity to marek's disease. 197893038
period-amplitude analysis of emg from slow and fast extensors of cat during locomotion and jumping.a real-time period-amplitude analysis program for emg involving the detection of events consisting of the period and amplitude difference between maxima and minima was used to study the activity patterns of fast and slow, hind and forelimb extensors during treadmill locomotion and jumping. events were stored in a two-dimensional table providing an easily interpreted quantification of frequency and amplitude parameters of single emg bursts which were characterized over a range of movements by the ...197991484
[indices of the activity of the pathological process in chronic pneumonias]. 200192858
effects of 15 vs 60 second enamel acid conditioning on adhesion and morphology. 20123532043
influence of antibiotics on the faecal excretion of bile pigments in healthy subjects.we have evaluated the effects of 10 antibiotics, given orally for 6 days to healthy subjects, on faecal excretion of urobilinogen. intake of bacitracin, vancomycin, clindamycin, erythromycin, and ampicillin resulted in a pronounced suppression of the faecal excretion of urobilinogen (p less than 0.05). intake of doxycycline, metronidazole, nalidixic acid, ofloxacin, and trimethoprim/sulphamethoxazole had no significant effect. the effects of three antibiotics-ampicillin, clindamycin, and metroni ...20133775264
predictive behavior of optokinetic eye movements.optokinetic nystagmus is often thought of as a "primitive" oculomotor response, while smooth pursuit is thought of as a "higher" one. we have used conditions that are usually thought of as eliciting optokinetic responses; i.e., large-field stimuli confined to the retinal periphery, and instructions to subjects to respond passively. in spite of this, the responses showed predictive behavior similar to that described for smooth pursuit.20103224671
hepatic injury in chronic iron overload. role of lipid both hereditary hemochromatosis and in the various forms of secondary hemochromatosis, there is a pathologic expansion of body iron stores due mainly to an increase in absorption of dietary iron. excess deposition of iron in the parenchymal tissues of several organs (e.g. liver, heart, pancreas, joints, endocrine glands) results in cell injury and functional insufficiency. in the liver, the major pathological manifestations of chronic iron overload are fibrosis and ultimately cirrhosis. evide ...20092663196
[independent controls of quality in therapeutic trials. apropos of an experience of 11 external audits of clinical investigators performed in 2 european multicenter trials]. 20113067418
[use of chickpea (cicer arietinum l.) in non-dairy formulas. ii. nitrogen balance in children with lactose intolerance, fed with a formula based on chickpea and a commercial soybean product].the nutritive value of chick-pea and soy infant formulas was evaluated. nitrogen balance was performed in 17 malnourished babies, seven of which were fed with the chick-pea formula, and 10 with the soy commercial formula (sobee). the percentage of absorption, retention and biological value of the chick-pea formula were 72.4, 26.4 and 35.1, respectively and 69.6, 24.3 and 34.0 in the same order, with the soy formula. since the nutritional quality of the chick-pea was not different to the commerci ...20113146951
di-(2-ethylhexyl) phthalate--missing links. 20113209145
[israel. always room for the parents in the pediatric ward]. 20123526613
depletion of monoamine transmitters by tetrabenazine in brain tissue in huntington's disease.the neurochemical effect of tetrabenazine was assessed by determining the levels of dopamine, noradrenaline and 5-hydroxytryptamine and their metabolites in post-mortem brain from huntington's disease patients with or without a history of tetrabenazine treatment. the tetrabenazine-treated group showed a general description of monoamines in all regions studied, the greatest reduction being dopamine in the caudate. this provides the basis for the effect of tetrabenzine on chorea, while monoamine l ...20102901681
silver staining of native and denatured eucaryotic dna in agarose gels.a modified method of silver staining for native and denatured eucaryotic dna in 1% agarose gel is described. this method is at least fivefold more sensitive than ethidium bromide staining, with a detection limit of 2.5 ng for total dna. the calibration curve is linear within the range 5-30 ng of single-stranded and double-stranded dna. this method is especially advantageous for electrophoretic assessment of dna molecular weights.20082446526
effects of physical conditioning on the heart size and wall thickness of college women.m-mode echocardiograms were obtained from 40 sedentary college women, 8 sprinters, 6 distance runners, 10 swimmers, 9 basketball players, 8 dancers, and 10 sedentary men (ages 19 to 31 yr). treadmill stress tests were performed by all groups except the basketball players. the aerobic capacities of the athletes were 30 to 48% greater (p less than 0.05) than the sedentary subjects. the athletes exhibited trends toward higher than average left ventricular (lv) end-diastolic dimensions (7 to 25%), l ...20133683147
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