| continuous dielectrophoretic separation of cell mixtures. | use of stream-centered dielectrophoresis (1-4) produced continuous separations on three cell mixtures (1) chorella vulgaris with netrium digitus, (2) ankistrodesmus falcatus with staurastrum gracile, and (3) saccharomyces cerevisiae with netrium digitus. maximal separations were obtained for these mixtures of live cells at 100 khz, 600 khz, and 2.0 mhz, respectively. the technique was restricted to a frequency range of 0.01-32 mhz, and to suspensions of low conductivity in which microorganisms s ... | 1979 | 95165 |
| mitral valve repair for significant mitral insufficiency. | there has been skepticism since the early days of open heart surgery that good long-term or even short-term results were possible with repair of pure mitral insufficiency. the authors report 145 patients in whom a markedly insufficient mitral valve was repaired 6 months to 17 years previously and another 55 patients in whom repair of the insufficient mitral valve was performed along with myocardial revascularization from 6 months to 7 years previously. comparative data with other published work ... | 1978 | 98030 |
| plasma membrane vesiculation: a cellular response to injury. | the shedding of plasma membrane vesicles has been shown to result from exposure of monolayer cell cultures to formaldehyde and other sulfhydryl blocking agents. incubation of cells in concentrations of these agents as low as 5 to 10 mm for intervals as brief as fifteen minutes is effective (scott, 1976). plasma membrane vesiculation has been shown to be an energy-dependent process that requires ca++ and physiological temperature. following plasma membrane vesiculation, cell monolayers appear int ... | 1978 | 98904 |
| pfkb and pfkc loci of escherichia coli. | mutants lacking escherichia coli phosphofructokinase (pfka, 78 min) are suppressed by the unlinked pfkb1 mutation, which restores some enzyme activity (morrissey and fraenkel, 1972). we here describe a secondary mutation at pfkb, "pfkb-," which abolishes the suppression as well as the low residual activity of unsuppressed pfka mutants. pfkb is at about 33 min. with the gene order grod-pps-phes-pfkb. a positive selection was found that yielded both the pfkb-mutations and a new similar mutation, p ... | 1975 | 125264 |
| acidic glycosaminoglycans in human kidney tissue. | the acidic glycosaminoglycans (agag) in normal human kidneys were fractionated on dowex 1-x2 columns and analysed by electrophoretic separation in three buffers on cellulose acetate membranes and gel filtration on sephadex g-100 columns, before and after digestion with chondroitinases and streptomyces hyaluronidase. thin-layer chromatography was also performed to separate glucosamine from galactosamine moieties. enzymatic digestion combined with electrophoretic characterization indicated that he ... | 1975 | 126123 |
| behavioral effects of dibutyryl cyclic 3'5'amp and biogenic amines in rats. | white male wistar rats were injected intraventricularly with 200 mug of dibutyryl cyclic 3'5'amp (damp. 30 min later part of animals was injected intraventricularly with 10 mug of dopamine (da), 10 mug of 5-hydroxytryptamine (5-ht) or 50 mug of acetylcholine (ach). immediately after injection of the amines the time of walking, convulsions, immobility and number of jumps during 10 min periods of observation was measured. damp induced excitation of animals expressed by convulsions, jumping and sho ... | 1975 | 165657 |
| complete klüver-bucy syndrome in man. | a 22 year old right-handed man suffered a viral meningoencephalitis, possibly herpetic, resulting in bilateral damage to the temporal lobes as confirmed by appropriate clinical, electrophysiological and neuroradiological studies. extended clinical neuropsychological evaluation documented all the characteristic features of the syndrome described by klüver and bucy following bilateral ablation of the temporal lobes in adult rhesus monkeys, including "psychic blindness," oral exploration, hypermeta ... | 1975 | 168031 |
| the effect of anti-lymphocyte and anti-thymocyte serum on the pathogenesis of rauscher leukaemia in inbred mouse strains. | rauscher virus causes in inbred balb/c mice a rapidly progressing hyperacute, in c57b1/10sn mice an incipient, spontaneously healing leukaemia. in dba/1 and dba/2 mice the appearance of leukaemia is followed by a partial remissions then by an exacerbation of the disease. the infection in c57b1/10sn, dba/1 and dba/2 mice results in a significant tumour-specific immune response. inhibition of the immune response is followed by an increased progression of leukaemia in dba/1 and dba/2 mice only. it ... | 1976 | 1088332 |
| effects of contrast agents on the blood-brain barrier. an electron microscopic study. | to determine if contrast agents after the blood-brain barrier by opening tight junctions between endothelial cells and by increasing pinocytosis, the distribution of horseradish peroxidase (hrp) was evaluated after intracarotid injections of contrast media. hrp did not cross the endothelium of cerebral blood vessels. tight junctions remained closed. there was increased endothelial cell pinocytosis and swelling of astrocyte end-feet. | 1975 | 1138267 |
| variations of neurohypophysial function in normally cycling women. | using a neurophysin radioimmunoassay, we have studied basal neurohypophysial function in seven normal women. an increase in neurophysin blood levels has been demonstrated during the ovulatory and/or luteal phase as compared to the follicular phase; these variations are related to the changes in the circulating levels of 17beta-estradiol. the data provide additional evidence for a relationship between estrogens and neurohyprophysial function, as previously shown following exogenous administration ... | 1975 | 1150865 |
| detection of soluble antigens by the reverse passive haemagglutination assay. | a series of parameters that influence coupling of antibodies to the surface of erythrocytes with cr3+ as well as the sensitivity and specificity of the reverse passive haemagglutination (rph) assay in various antigen-antibody systems have been studied. the optimum coating of erythrocytes with antibodies was achieved at a final concentration of 30 micrograms crcl3/ml with a protein antibody/crcl3 ratio of 3.66 for most antibody igg tested (anti-human igg, anti-human albumin, anti-human hemoglobin ... | 1992 | 1304825 |
| inherited deletion of chromosome (21p-) in a child with congenital malformation and psychomotor retardation. | | 1992 | 1428153 |
| retinoylation of cytokeratins in normal human epidermal keratinocytes. | retinoylation (retinoic acid acylation) is a covalent modification of proteins occurring in a variety of eukaryotic cell lines. in this study, we found that proteins in undifferentiated and squamous-differentiated normal human epidermal keratinocytes were retinoylated after treatment with [3h]retinoic acid. the major retinoylated proteins were identified as cytokeratins based on their profile in two-dimensional gel electrophoresis and their immunoreactivity with anti-keratin monoclonal antibodie ... | 1991 | 1718279 |
| inhibition of 7-hydroxymethotrexate formation by amsacrine. | the inhibition of methotrexate (mtx) biotransformation to 7-hydroxymethotrexate (7-oh-mtx) by 4'-(9-acridinylamino)-methanesulfon-m-anisidide (mamsa) was studied in bile-drained rats in vivo and in incubates of isolated rat hepatocytes and rat-liver homogenate in vitro. in vivo, i.v. administration of 10 mg/kg mamsa prior to [3h]-mtx infusion (50 mg/kg) led to a significant alteration in 7-oh-mtx kinetics. 7-oh-mtx peak concentrations and auc in bile and serum were reduced by 75% and the recover ... | 1991 | 1914082 |
| peptide amphipathy: a new strategy in design of potential insecticides. | a 30-residue peptide [yaa(kala)6laa] with an amphipathic helix repeat unit of lys-ala-leu-ala (kala) was synthesized as both the l- and the d-isomer. the peptide was shown to form alpha-helices and lyse lipid vesicles in a ph dependent fashion. the calculated helical amphipathic moment is +1.19 kcal/residue and the mean residue hydrophobicity is +0.4 kcal/residue. the formation of alpha-helices as the ph is increased is similar to poly-lysine, yielding a pk 10.2. though not toxic when fed to ins ... | 1991 | 2045216 |
| mycoplasma incognitus: a workshop. | | 1990 | 2339753 |
| sequence of myosin-crossreactive epitopes of streptococcal m protein. | group a streptococcal m proteins contain epitopes that crossreact with sarcolemmal membrane proteins of human myocardium and myosin. in the present study, synthetic peptide copies spanning the entire 197-residue pepsin extracted fragment of type 5 m protein were used to localize the myosin-crossreactive epitopes of the molecule. peptide 84-116 inhibited by 75% the binding of myosin-crossreactive antibodies evoked by pep m5, as determined by elisa. immunoblot inhibition studies confirmed that pep ... | 1986 | 2430047 |
| the time dependence of training-induced increase in skeletal muscle capillarization and the spatial capillary to fibre relationship in normal and neovascularized skeletal muscle of rats. | one hundred and eighty-four rats of different ages were investigated regarding the basic capillary-fibre array and the array resulting from capillary proliferation induced by swimming training and dipyridamole treatment. the time dependence of the training-induced capillary increase in the muscle was also investigated. sections of the medial portion of the quadriceps femoris muscle were evaluated in light microscope for total capillarization, fibre area and fibre type composition. after 4 and 8 ... | 1986 | 2430430 |
| corneal toxicity studies in rabbits and dogs with hydroxyethyl cellulose and benzalkonium chloride. | hydroxyethyl cellulose (hec) is used as a viscosity-enhancing agent in ophthalmic formulations to prolong corneal contact time and increase intraocular drug levels. benzalkonium chloride (bak) is the preservative most frequently used in ophthalmic formulations. corneal epithelial changes were seen by slit lamp and light microscopic examination in rabbits but not dogs after multiple instillations of an ophthalmic vehicle containing 0.01% bak and 0.5% hec. microscopically, there was sloughing of s ... | 1989 | 2612782 |
| pharmacokinetics of dactimicin in rats. | dactimicin is a new pseudo-disaccharidic aminoglycosidic antibiotic produced by dactylosporangium matsuzakiense. the aim of the present research was to evaluate the pharmacokinetics of dactimicin intramuscularly administered, at the dosage of 20 mg/kg, in male sprague-dawley rats with an average b.w. of 200-220 g. dactimicin levels were assessed by using a microbiological method (agar diffusion) employing bacillus subtilis atcc 6633 as test organism. samples were collected immediately before and ... | 1989 | 2637794 |
| pharmacokinetics of dactimicin in rats. | dactimicin is a new pseudo-disaccharidic aminoglycosidic antibiotic produced by dactylosporangium matsuzakiense. the aim of the present research was to evaluate the pharmacokinetics of dactimicin intramuscularly administered, at the dosage of 20 mg/kg, in male sprague-dawley rats with an average b.w. of 200-220 g. dactimicin levels were assessed by using a microbiological method (agar diffusion) employing bacillus subtilis atcc 6633 as test organism. samples were collected immediately before and ... | 1989 | 2637794 |
| assembly and release of hiv-1 precursor pr55gag virus-like particles from recombinant baculovirus-infected insect cells. | the unprocessed gag precursor from hiv-1, when expressed in recombinant baculovirus-infected insect cells, is targeted to the plasma membrane and assembles in 100-120 nm particles budding from the cell surface. this process mimics hiv immature particle formation and is dependent on myristoylation of the n-terminal glycine, as deletion of the latter results in particle accumulation in the cytoplasm and, interestingly, in the nucleus, pointing to a potential role of this non-fatty-acid-acylated sp ... | 1989 | 2676191 |
| ovum transport in the rat oviductal ampulla in the absence of muscle contractility. | ovum transport in mammalian oviducts involves two main effectors: ciliary motility and muscle contractility. to study the relative contribution of cilia to ovum transport in the rat, we blocked smooth muscle activity with isoproterenol, a beta-adrenergic agonist, and measured transport rates of surrogate ova in situ. transport rates before isoproterenol administration were 0.04 mm/s in the cephalic ampulla and 0.03 mm/s in the caudal ampulla; rates were unchanged after administration of isoprote ... | 1989 | 2775809 |
| taurine modulates glycine response in xenopus oocytes injected with messenger rna from mouse brain. | the modulatory action of taurine on the glycine response was investigated in xenopus oocytes injected with messenger rna from mouse brainstem under voltage-clamped condition. taurine competitively inhibited the glycine response in a dose-dependent manner. this inhibition was insensitive to bicuculline and intracellularly injected egta. the results suggest that taurine could directly modulate glycinergic neurotransmission in the central nervous system. | 1988 | 2850085 |
| analgesic effectiveness of topically applied dynorphin on human dental pulp. | | 1986 | 2876436 |
| metabolism and nephrotoxicity of tetralin in male fischer 344 rats. | tetralin, a component of fuels, solvents, and varnishes, is metabolized in male fischer 344 rats to 1-tetralol, 2-tetralol, 2-hydroxyl-1-tetralone, 4-hydroxyl-1-tetralone, 1,2-tetralindiol, and 1,4-tetralindiol. rats treated with tetralin demonstrated the classic lesions of hydrocarbon-induced nephropathy. | 1989 | 2926829 |
| indomethacin sensitive suppressor-cell activity in head and neck cancer patients. the role of the adherent mononuclear cell. | head and neck cancer (h&n ca) patients have known depression of cell-mediated immunity. there is suggestive evidence that prostaglandin (pge2)-secreting cells may be a major factor. the authors have sought to determine the role of pge2-releasing monocytes-macrophages in this immune depression by determining the effects of adherent cell depletion and by measuring the effects of indomethacin, a pge2 synthetase inhibitor, on selected tests of lymphocyte function. lymphocyte stimulation with phytohe ... | 1988 | 2962730 |
| effects of electrical stimulation and choline availability on the release and contents of acetylcholine and choline in superfused slices from rat striatum. | the presence of 5 or 20 microm choline in the eserinized medium superfusing striatal slices enhanced the spontaneous release of acetylcholine (ach) at both concentrations and, at 20 microm, the release of transmitter evoked by electrical field stimulation. neither the electrical stimulation nor the addition of choline altered choline acetyltransferase activity. these results show that ach release is dependent on the availability of extracellular choline. the rate of choline efflux was 7 times hi ... | 1985 | 3003350 |
| effect of saturated and unsaturated fatty acids on the oxidative metabolism of human neutrophils. the role of calcium ion in the extracellular medium. | the ability of fatty acids to stimulate the generation of superoxide anion (o2-) by human neutrophils was investigated with respect to their krafft points. saturated (myristic acid) and unsaturated (elaidic and oleic acid) induced a marked o2- generation and release from human neutrophils at ph 7.4 in the absence of ca2+, while 0.3 mm ca2+ inhibited both myristic acid and elaidic acid-induced o2- release. [14c]myristic acid association with neutrophils was reduced by addition of ca2+, whereas ol ... | 1986 | 3021216 |
| effect of saturated and unsaturated fatty acids on the oxidative metabolism of human neutrophils. the role of calcium ion in the extracellular medium. | the ability of fatty acids to stimulate the generation of superoxide anion (o2-) by human neutrophils was investigated with respect to their krafft points. saturated (myristic acid) and unsaturated (elaidic and oleic acid) induced a marked o2- generation and release from human neutrophils at ph 7.4 in the absence of ca2+, while 0.3 mm ca2+ inhibited both myristic acid and elaidic acid-induced o2- release. [14c]myristic acid association with neutrophils was reduced by addition of ca2+, whereas ol ... | 1986 | 3021216 |
| delayed amplification of cytomegalovirus infection in the placenta and maternal tissues during late gestation. | to stimulate first-trimester human cytomegalovirus infection, pregnant guinea pigs were inoculated with a low dose of guinea pig cytomegalovirus during the first trimester of pregnancy. maternal viremia, which was cleared by 2 weeks after inoculation, was found to reappear near the time of delivery in one third of the animals tested. the virus, first detected in the placenta during initial maternal viremia, replicated after the time when maternal blood was cleared of virus, although high titers ... | 1987 | 3034060 |
| recovery of herpes simplex virus from the corneas of experimentally infected rabbits. | rabbits were inoculated in the left cornea with one of three strains of herpes simplex virus (hsv) i.e. hsv-1 strain 17, hsv-1 strain mckrae, hsv-2 strain hg52, or with and hsv-1 mckrae/hsv-2 hg52 recombinant r40/2. fifty-nine to 67 days after inoculation trigeminal ganglia and corneas were explanted and screened for release of infectious virus. virus was isolated from all left trigeminal ganglia after organ culture irrespective of viral strain. virus was isolated from three of 16 corneas of ani ... | 1987 | 3037020 |
| preclinical evaluation of lovastatin. | administration of lovastatin to animals at high dosage levels produces a broad spectrum of toxicity. this toxicity is expected based on the critical nature of the target enzyme (hmg coa reductase) and the magnitude of the dosage levels used. the information reviewed in this paper demonstrates that these adverse findings in animals do not predict significant risk in humans. the reason for this derives from the fact that all the available evidence suggests that the adverse effects observed are pro ... | 1988 | 3055920 |
| lepromin conversion induced by a 'sub-unit' vaccine from icrc bacilli. | | 1988 | 3071521 |
| coexpression of human growth hormone-releasing factor 1-37-like and alpha-melanotropin-like immunoreactivities in neurones of the rat lateral dorsal hypothalamus. | antibodies recognizing the 29-37 sequence of the human somatocrinin specifically stain a large population of interneurones located in the lateral dorsal hypothalamus. staining comparisons revealed that these perikarya also contain alpha-msh-like immunoreactivity. the neurones exhibiting human grf1-37-like immunoreactivity correspond to the system previously shown to present alpha-msh-like and rat crf-like immunoreactivities. | 1986 | 3088497 |
| coexpression of human growth hormone-releasing factor 1-37-like and alpha-melanotropin-like immunoreactivities in neurones of the rat lateral dorsal hypothalamus. | antibodies recognizing the 29-37 sequence of the human somatocrinin specifically stain a large population of interneurones located in the lateral dorsal hypothalamus. staining comparisons revealed that these perikarya also contain alpha-msh-like immunoreactivity. the neurones exhibiting human grf1-37-like immunoreactivity correspond to the system previously shown to present alpha-msh-like and rat crf-like immunoreactivities. | 1986 | 3088497 |
| [serologic studies of spotted fever group rickettsiosis occurring in muroto-city, kochi prefecture]. | | 1986 | 3090165 |
| chemotherapy of pulmonary tuberculosis in britain. | | 1988 | 3123192 |
| dual mechanism of repression at a distance in the lac operon. | the mechanism by which the internal lacz gene sequence o2 influences lac repression was investigated by using in vivo footprinting of operon mutants. quantitative in vivo binding curves show that o2 strengthens by approximately 3-fold repressor binding to o1 that is located 400 base pairs upstream at the transcription start site. the internal o2 sequence also contributes to repression by a second mechanism: repressor bound internally blocks elongation of beta-galactosidase gene expression. this ... | 1988 | 3143112 |
| isolation of protease-proficient, recombinase-deficient reca mutants of escherichia coli k-12. | we isolated reca mutants with altered protease activity and then examined recombinase activity to determine whether the protease and recombinase functions of the reca protein of escherichia coli are separable. we found five mutants that had moderately strong constitutive reca protease activity but no recombinase activity above the delta reca strain background, the first clear-cut examples of mutants of this class, designated prtc rec-. we also isolated 65 mutants that were protease-defective tow ... | 1985 | 3160687 |
| hemolytic uremic syndrome associated with shigellosis: report of two cases. | two patients with hemolytic uremic syndrome admitted to udornthani hospital, thailand, were reported. the preceding illness was shigellosis. the stool culture was positive for shigella dysenteriae in one patient and shigella flexneri in another. the management was successful with peritoneal dialysis in one and symptomatic treatment in another. both patients had complete recovery. | 1987 | 3313740 |
| some observations on sympatric populations of the malaria vectors anopheles leucosphyrus and anopheles balabacensis in a village-forest setting in south kalimantan. | human bait collections of biting anopheline mosquitoes were made on five consecutive nights during september 1986 in a remote village located in a heavily forested area of south kalimantan, indonesia. anopheles leucosphyrus and an. balabacensis comprised 97.7% of the total number of specimens collected outside houses in the village. anopheles balabacensis were slightly fewer in total numbers than leucosphyrus. mosquitoes were collected simultaneously in the village and the forest on two nights. ... | 1987 | 3313741 |
| [the effect of free fatty acids on the leucine oxidation of human lymphocytes]. | | 1988 | 3377747 |
| nuclear inclusions in rostellar cells of echinococcus multilocularis (cestoda). | | 1988 | 3387413 |
| effects of amiloride and diethyl pyrocarbonate on csf hco-3 and ventilation in hypercapnia. | amiloride (10(-3) m), a na+-h+ countertransport inhibitor, infused into the cisterna magna (10 microliter/min for 40 min) of ketamine-xylazine-anesthetized rabbits decreased the cerebrospinal fluid (csf) hco3- response to 3 h of hypercapnia [arterial pco2 (paco2) = 60 torr] by 21.6% (mean delta csf [hco3-]/delta paco2 0.232 vs. 0.296 mmol.l-1.torr-1, p less than 0.05). diethyl pyrocarbonate (depc, 10(-3) m), a histidine-blocking agent, infused into the cisterna magna decreased the csf hco3- resp ... | 1988 | 3403466 |
| effects of monoclonal antibody against pmsg administered shortly after the preovulatory lh surge on time and number of ovulations in pmsg/pg-treated cows. | normally cyclic heifers received 2500 i.u. pmsg i.m. at day 10 of the oestrous cycle and 15 mg prostaglandin (pg) i.m. 48 h later. from 30 h after pg the lh concentration in the peripheral blood was estimated every hour using a rapid ria method which allowed the lh concentration to be known within 4 h. monoclonal antibody against pmsg was injected in the jugular vein of 29 heifers at 4.8 h after the maximum of the preovulatory lh peak; 28 heifers were not treated with anti-pmsg (controls). perip ... | 1987 | 3430470 |
| [functional status of the rat insular apparatus and adrenal cortex at early periods after irradiation]. | as early as 0.5-3 h after x-irradiation of rats with a lethal dose of 12 gy glucocorticoid activity of adrenal cortex was enhanced and 11-oxycorticosteroid level in blood was increased. the increasing of the immunoreactive insulin content of blood was registered at the background of hypercorticoidism and normal function of insular apparatus during the first hours following irradiation. at later times (24-72 h), a stable hypercorticoidism developed, the ability of beta-cells to react adequately t ... | 1986 | 3534939 |
| protein sorting in yeast: mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway. | we have devised a genetic selection for mutant yeast cells that fail to properly deliver the vacuolar glycoprotein cpy to the lysosome-like vacuole. this has allowed us to identify mutations in eight vpl complementation groups that result in aberrant secretion of up to approximately 90% of the immunoreactive cpy. other soluble vacuolar proteins are also affected by each vpl mutation, demonstrating that a sorting system for multiple vacuolar proteins exists in yeast. mislocalized cpy apparently t ... | 1986 | 3536126 |
| the effect of carbonyl cyanide trifluoromethoxyphenylhydrazone and methylamine on the processing and secretion of the glycoprotein hormone chorionic gonadotropin by human choriocarcinoma cells. | carbonyl cyanide trifluoromethoxyphenylhydrazone (fccp), a protonophore, and methylamine, a weak base, agents that dissipate hydrogen gradients across cellular membranes, were used to probe the coupling of hydrogen gradients to the processing and secretion of the glycoprotein hormone hcg by human choriocarcinoma cells (jar) in culture. both drugs disrupted the processing of asparagine-linked oligosaccharides such that the secreted hcg forms contained mostly high mannose rather than complex oligo ... | 1986 | 3720670 |
| fibronectin and laminin promote in vitro attachment and outgrowth of mouse blastocysts. | the process of mammalian implantation has been investigated using an in vitro model system wherein the trophoblast cells of mouse blastocysts attach to and outgrowth on tissue culture plates containing a complex medium. we now report that two extracellular matrix glycoproteins, fibronectin and laminin, when individually precoated on tissue culture plates promoted in vitro attachment and outgrowth of mouse blastocysts in serum-free medium. the kinetics of attachment and outgrowth processes in the ... | 1986 | 3732618 |
| experimental anaerobic liver abscess: observations on treatment. | various treatment modalities for solitary anaerobic liver abscesses were evaluated in a recently-described rabbit model. in the first phase of the experiment, 35 rabbits with liver abscesses induced with bacteroides fragilis and fusobacterium necrophorum were randomized into four groups: surgical drainage alone, drainage plus clindamycin 150 mg im 8-hourly, clindamycin alone, and untreated controls. serum clindamycin concentrations in rabbits were similar to those achieved in humans. the surviva ... | 1986 | 3747743 |
| characterization of proopiomelanocortin mrna detected by in situ hybridization. | in situ hybridization is a method for detecting specific nucleotide sequences by using a labeled complementary nucleic acid probe. we have characterized in situ hybridization in rat pituitary using a cdna probe directed against a portion of proopiomelanocortin (pomc) mrna to show its specificity in tissue sections. this characterization includes the size of the target mrna from tissue processed for in situ hybridization, the dissociation pattern of the cdna:mrna hybrid, and quantitation of chang ... | 1986 | 3753720 |
| induction of early breeding in red deer (cervus elaphus) by melatonin. | lactating (n = 12) and non-lactating (n = 6) red deer hinds and one stag at pasture were given concentrates (500 g/head) containing melatonin (5 mg/head) daily at 16:00 h from 18 june to 16 october. the stag shed the antler velvet and started rutting 5 weeks ahead of untreated stags, and hinds had their first oestrus and ovulation of the breeding season in mid-september, 5 weeks in advance of control lactating (n = 9) and non-lactating (n = 5) hinds. treated hinds were allowed to mate with the t ... | 1986 | 3754582 |
| the effect on pregnancy of intrauterine administration of antibodies against two pregnancy-associated murine proteins: murine pregnancy-specific beta 1-glycoprotein and murine pregnancy-associated alpha 2-glycoprotein. | intrauterine administration of 100 arbitrary units (au) of purified monospecific rabbit anti murine pregnancy specific beta 1-glycoprotein antibodies resulted in the loss of the fetuses in pregnant mice (14 out of 14). by contrast, a similar treatment with 100 au of rabbit anti murine pregnancy-associated alpha 2-glycoprotein had an effect similar to saline on the outcome of pregnancy. intravenous administration of 1000 au of rabbit anti murine pregnancy specific beta 1-glycoprotein during pregn ... | 1985 | 3878707 |
| the effect on pregnancy of intrauterine administration of antibodies against two pregnancy-associated murine proteins: murine pregnancy-specific beta 1-glycoprotein and murine pregnancy-associated alpha 2-glycoprotein. | intrauterine administration of 100 arbitrary units (au) of purified monospecific rabbit anti murine pregnancy specific beta 1-glycoprotein antibodies resulted in the loss of the fetuses in pregnant mice (14 out of 14). by contrast, a similar treatment with 100 au of rabbit anti murine pregnancy-associated alpha 2-glycoprotein had an effect similar to saline on the outcome of pregnancy. intravenous administration of 1000 au of rabbit anti murine pregnancy specific beta 1-glycoprotein during pregn ... | 1985 | 3878707 |
| the c-myc oncogene is translocated to the involved chromosome 12 in mouse plasmacytoma. | although it is known that the c-myc oncogene is rearranged in a head-to-head fashion with the immunoglobulin heavy chain locus in mouse plasmacytomas, it has not been clear whether the c-myc oncogene is translocated to the heavy chain locus on mouse chromosome 12 or whether the heavy chain locus is translocated to the c-myc locus on mouse chromosome 15. to determine which of these two possibilities is correct, we hybridized chinese hamster fibroblasts with j558 mouse plasmacytoma cells that carr ... | 1985 | 3923490 |
| sham feeding in rats after ventromedial hypothalamic lesions and vagotomy. | sham feeding was examined in female rats with ventromedial hypothalamic (vmh) lesions with or without abdominal vagotomy. in experiment 1, intact rats consumed more than twice as much sweet milk during 1-hr tests of sham feeding (m = 13.0 ml) as they did when feeding normally (m = 5.5 ml). rats with vmh lesions showed exaggerated sham feeding, which was elevated almost fourfold (m = 56.6 ml) over their already high normal feeding baseline (m = 15.1 ml). in experiment 2, vagotomy substantially re ... | 1986 | 3954881 |
| the projection of different retinal ganglion cell classes to the dorsal lateral geniculate nucleus in the hooded rat. | the morphology of retinal ganglion cells which project to different parts of the dorsal lateral geniculate nucleus (dlg) in the hooded rat has been investigated. small amounts of a retrograde tracer (horseradish peroxidase) were injected into the dlg, then labelled retinal ganglion cells were examined in retinal wholemounts. after injections into different parts of the dlg, differences were noted in the size, morphology and retinal distribution of labelled retinal ganglion cells. specifically, a ... | 1986 | 3956639 |
| [treatment of neonatal jaundice by efficient phototherapy]. | idiopathic neonatal jaundice derives from an initial insufficiency of all processes which metabolize hydrophobic bilirubin into diglucuronide excretable in bile. the term 'neonatal hyperbilirubinemia' should only be used when there is a potential risk of bilirubin intoxication. thus, the concept hyperbilirubinemia is not necessarily linked to the exceeding of a certain threshold value, but rather to the maturity of the child and its clinical condition. in this sense, hyperbilirubinemia is, there ... | 1985 | 3993136 |
| preliminary studies of the histopathological responses to ti-13% cu casting alloys. | a preliminary study of some of the biological properties of a new dental casting alloy (ti-13% cu) was undertaken by employing the skeletal muscle implantation test in rabbits. routine histopathological and chemical analysis techniques were utilized to study in vivo tissue reactions of skeletal muscle to this alloy. a moderately thick, somewhat cellular fibrous connective tissue capsule surrounded the implants after 2 wk. remodelling of the fibrous tissue into a thin acellular tissue capsule occ ... | 1985 | 4052537 |
| preliminary studies of the histopathological responses to ti-13% cu casting alloys. | a preliminary study of some of the biological properties of a new dental casting alloy (ti-13% cu) was undertaken by employing the skeletal muscle implantation test in rabbits. routine histopathological and chemical analysis techniques were utilized to study in vivo tissue reactions of skeletal muscle to this alloy. a moderately thick, somewhat cellular fibrous connective tissue capsule surrounded the implants after 2 wk. remodelling of the fibrous tissue into a thin acellular tissue capsule occ ... | 1985 | 4052537 |
| [the influence of the vagus nerves on the hemodynamics and tubular activity of the kidneys]. | | 1974 | 4142593 |
| temperature changes induced by imidazoline sympathomimetics in the rat. | | 1969 | 4181834 |
| [correlation of tuberculin sensitivity before and after bcg vaccination]. | | 1967 | 4235702 |
| inhibition of brain sodium- and potassium-stimulated adenosine triphosphatase activity by chlorpromazine free radical. | | 1968 | 4235718 |
| [comparative study of the convulsion provoking activity of actinomycin d and methionine sulfoximine injected into the cerebrospinal fluid of dogs]. | | 1971 | 4262072 |
| the effects of cesarean derivation and foster nursing procedures on enzootic viruses of the lsh strain of inbred hamsters. | | 1970 | 4315778 |
| purification of a ribonuclease inhibitor from novikoff hepatoma supernatant fraction. | | 1974 | 4370304 |
| ecology of the brown spiny mouse mus p. platythrix (bennett) and the indian field mouse mus b. booduga (gray). | | 1974 | 4442970 |
| [proceedings: control system of the reticular formation of the medulla oblongata over trigeminal motor neurons]. | | 1974 | 4478302 |
| the qualitative analysis and preparation of phage transfer rna. | | 1974 | 4605320 |
| experimental transmission of an isolate of nosema strigeoideae hussey, 1971, to fasciola hepatica. | | 1972 | 4629830 |
| experimental transmission of an isolate of nosema strigeoideae hussey, 1971, to fasciola hepatica. | | 1972 | 4629830 |
| nuclear magnetic resonance studies suggestive of a lipid population tightly bound to myelin structural proteins. | | 1972 | 4635369 |
| on the chemistry of porphobilinogen synthesis of an aminomethyldipyrrylmethane. | | 1974 | 4836426 |
| on the process of cellular division in escherichia coli: replication of the bacterial chromosome under control of prophage p2. | the temperature-sensitive mutant crt46 of escherichia coli k12 is unable to initiate new rounds of dna replication at 42 degrees c. mutants of bacteriophage p2 have been isolated, which, in the prophage state, allow mutant crt46 to grow at 42 degrees c. the lysogenic bacteria that grow at 42 degrees c are apparently replicating under the control of prophage p2, which substitutes for the bacterial initiation system. the ability of prophage p2 cause this suppression phenomenon depends on the posit ... | 1971 | 4944622 |
| [age-dependent changes in human lingual mucosa]. | | 1968 | 4970291 |
| oestrogen synthesis in rat ovaries in vitro: effects of endogenous and exogenous gonadotrophins. | | 1972 | 5064671 |
| effect of age of hen on albumen height and ph. | | 1971 | 5094400 |
| computed tomographic evaluation of the breast. | experience with a dedicated breast ct scanner (general electric ct/m) using a contrast medium enhancement technique indicates that ct is superior to mammography, thermography, or physical examination for diagnosing both benign and malignant mammary disease especially in dense, thick, or fibrocystic breasts. ct is capable of diagnosing totally unsuspected early miniature carcinomas. it can identify and differentiate potential precancerous lesions from benign fibrocystic disease, and is the diagno ... | 2000 | 98990 |
| cerebral perfusion pressure: a hemodynamic mechanism of mannitol and the postmannitol hemogram. | sixteen patients each received infusions of 1 g of mannitol per kg over 5 to 10 minutes, and serial determinations of intracranial pressure (icp), systemic arterial blood pressure (sabp), central venous pressure, cerebral perfusion pressure (cpp), hematocrit, hemoglobin, serum na+, k+, osmolarity, and fluid balance were carried out for 4 hours. urine output was replaced volume for volume with 5% dextrose in 0.45% nacl solution. we tested the hypothesis that patients with high (greater than or eq ... | 2010 | 3116451 |
| [polyradiculoneuritis in a heroin addict]. | | 2011 | 3157840 |
| [methodologic approach to the detection and evaluation of early signs of unfavorable effects of occupational factors on health]. | | 2012 | 3243482 |
| [epilepsy with centrotemporal (rolandic) spikes. a peculiar seizure disorder of childhood]. | the study presents the results of a long term investigation of 60 epileptic children with rolandic (centrotemporal) spikes in eeg. the results could be summarized as follows: the rolandic epilepsy is relatively frequent entity (13.4% of the total number of epileptic children). the age span was from 3--13 years, with a peak of age incidence between the 7th and 8th year of life. more than half of children had nocturnal fits only. from the clinical point of view 60% of children had generalized cris ... | 2000 | 101893 |
| letter: bromide intoxication. | | 2002 | 126712 |
| a sensitivity method for electrical impedance tomography. | | 2009 | 2632141 |
| a sensitivity method for electrical impedance tomography. | | 2009 | 2632141 |
| the role of algal antigenic determinants in the recognition of potential algal symbionts by cells of chlorohydra. | algal cells grown in the green hydra chlorohydra viridissima were shown to possess characteristic antigenic determinants not found in algae cultured in vitro. these antigenic determinants, including those localized on the algal cell surface, were shown to be responsible for the phagocytic recognition of potential algal symbionts by digestive cells of chlorohydra. the results of this study indicate the existence of two systems governing phagocytosis in chlorohydra, one specific for algal cells gr ... | 1999 | 84815 |
| primary malignant lymphoma of the heart. antemortem cytologic diagnosis. | a case of primary malignant lymphoma of the heart diagnosed cytologically is reported. the patient presented with pericardial tamponade and ventricular arrhythmias and developed rapidly progressive and intractable cardiac failure. two-dimensional echo-cardiography, which demonstrated the pericardial effusion, showed progressive impairment of the left ventricular contraction. the pericardial fluid contained malignant lymphoid cells. despite vigorous treatment and chemotherapy, the patient died wi ... | 2012 | 3466501 |
| the culture of colony forming units from the peripheral blood and bone marrow of children with acute lymphocytic leukemia. | | 2015 | 4528021 |
| systemic air embolism secondary to respiratory therapy in the neonate: six cases including one survivor. | systemic air embolism has been described as a complication of respiratory therapy using positive pressure ventilation. this is usually a dire, if not fatal occurrence. the incidence of this severe complication will likely increase with the advent of more vigorous and aggressive respiratory therapy of the respiratory distress syndrome in neonates. it is important for both the clinician and the radiologist to be aware of this entity, its etiology, and its probable increasing frequency. this paper ... | 2000 | 98984 |
| performance of cardiac pacemaker pulse generators. | | 2001 | 95319 |
| ultrastructure of muscle spindles in dystrophic mice. | | 2002 | 124017 |
| tryptophan in kinixys crosa hemoglobins. | the hemoglobins, thi and thii, isolated from the red cells of the testudinid kinixys crosa each have 3 tryptophan residues/18,000 daltons. total number of amino acid residues for the proteins are therefore 156 and 155/18,000 daltons respectively. | 2004 | 421787 |
| current issues in bioethics. demands, limits, and autonomy. | | 2008 | 2586385 |
| gut size and the digestion of fibrous diets by tetraonid birds. | a series of diets containing different proportions of heather was fed to red grouse. heather is the bird's main natural food and contains much fiber; the rest of each diet was a relatively low-fiber, grain-based formulation. with increasing heather and associated fiber contents, food intake increased and overall digestibility of heather was only 9.4%, but, when heather was eaten as the sole food by wild red grouse, its digestibility was 46%. adaptations to diets containing more heather included ... | 2008 | 2575129 |
| smoking cessation: role of nicotine dependence. | | 2011 | 3338332 |
| volunteer work in deaf community keeps this dental hygienist going. | | 2012 | 3483213 |
| [significance and necessity of metaphylactic studies in bladder cancer]. | | 2013 | 4140628 |
| histochemistry of mucus in the skin of the frog, rana pipiens. | | 2014 | 4191041 |