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the temporal evolution of hypoglycemic brain damage. i. light- and electron-microscopic findings in the rat cerebral cortex.in the course of a study on the pathogenesis of neuronal necrosis in severe hypoglycemia, the morphological characteristics reflecting reversible and irreversible neuronal lesions were examined as a function of time following normalization of blood glucose. to that end, closely spaced time intervals were studied in the rat cerebral cortex before, during, and up to 1 year after standardized pure hypoglycemic insults of 30 and 60 min of cerebral isoelectricity. both the superficial and deep layers ...19854024866
gonococcal conjunctivitis. 19744205793
[role of anti-brain antibodies in the development of mineralocorticoid deficiency]. 197985292
effects of noise on pure-tone thresholds in blackbirds (agelaius phoeniceus and molothrus ater) and pigeons (columba livia).blackbirds and pigeons were trained to detect tones in quiet and in broadband noise by using positive-reinforcement techniques. in experiment 1, thresholds in noise were obtained in blackbirds as a function of both tone frequency and noise intensity for a pulsed noise masker (noise gated on and off with tone). for blackbirds, critical ratios (the ratio of the power of the just-detectable tone in noise to the power of the noise masker) obtained in pulsed noise showed no consistent relation to ton ...19873568604
[relationship of the structure of specific somatic antigen polysaccharides in shigella dysenteriae bacteriae to the immunochemical properties]. 197985516
estrogenic control of spermidine/spermine n1-acetyltransferase activity in rat uterus. 19883076330
[distribution of antibodies against the human t-cell leukemia virus in healthy venezuelan adults]. 19853008469
[experimental study on the changes of bile acids and their fractions after liver ischemia].serum bile acids and their fractions in the systemic and portal vein were measured after liver ischemia of 0, 30, 60, and 90 minutes with extracorporeal venous bypass in 20 dogs. the following results were obtained: 1) total concentration of bile acids in the serum rapidly increased during the ischemic phase because of extinction of enterohepatic circulation due to flow of portal blood into the systemic circulation. 2) portal blood flow decreased after recirculation of the liver, and this decrea ...19892811841
[tumor metastasis and growth factors].massive investigations are being carried out on growth factors. growth factors are an important determinant for the formation of successive tumor metastasis at target organs. we review the findings, including our data, of growth factors in relation to tumor metastasis.19892679395
modification of allergen-induced airway obstruction and airway hyperresponsiveness in an allergic rabbit model by the selective platelet-activating factor antagonist, bn 52021.allergen challenge of eight ragweed-immunized rabbits elicited a prolonged airway obstruction that was evident during the 6-hour study period. airway responsiveness to histamine was enhanced 24 hours after allergen exposure (geometric mean of the 50% reduction in effective dose [ed50] of dynamic compliance [cdyn] before challenge, 3.46 mg/ml, decreased to 0.52 mg/ml after challenge, p less than 0.01; pulmonary resistance ed50 geometric mean before challenge, 3.50 mg/ml, decreased to 0.65 mg/ml a ...19892600327
air sampling for legionella. 19902232037
structure of the human centromere at metaphase.until recently the centromere was thought to be a relatively homogeneous region of densely packed heterochromatin with a single differentiated domain--the kinetochore--at its surface, representing the point of attachment of the mitotic spindle. we now know that the centromere of higher eukaryotes is composed of several domains that have been identified using antibody probes. somewhere within the domains are located both the factor(s) that control the disjunction of sister chromatids and the mole ...19902193435
plasmodium falciparum malaria: band 3 as a possible receptor during invasion of human erythrocytes.human erythrocyte band 3, a major membrane-spanning protein, was purified and incorporated into liposomes. these liposomes, at nanomolar concentrations of protein, inhibited invasion of human erythrocytes in vitro by the malaria parasite plasmodium falciparum. liposomes containing human band 3 were ten times more effective in inhibiting invasion than those with pig band 3 and six times more effective than liposomes containing human erythrocyte glycophorin. liposomes alone or liposomes containing ...19853880920
effects of althesin and its steroidal components on a variety of excised smooth muscle preparations. 1979262472
in vitro susceptibilities of bartonella and rickettsia spp. to fluoroquinolone antibiotics as determined by immunofluorescent antibody analysis of infected vero cell monolayers.the in vitro susceptibilities of bartonella and rickettsia spp. to different concentrations of ciprofloxacin, levofloxacin, ofloxacin and sparfloxacin in vero cell cultures, were determined by enumeration of immunofluorescent-stained bacilli. after incubation in a co(2)-enriched atmosphere, inocula were replaced and tested with media containing 12 different concentrations of each antibiotic in replicate for each species and the monolayers were re-incubated. growth status was determined by evalua ...200111673033
steroid production by quartered and capsular rat adrenal gland in response to haemorrhage.60 min after rapid bleeding (1.5--2.0 per cent of b. w.) both aldosterone and corticosterone production rate by quartered rat adrenals were found to be elevated. however, no difference was observed in the rate of aldosterone and corticosterone production by capsular adrenals of sham operated and hypovolaemic rats. corticosterone production rate by decapsulated adrenals was much more higher after haemorrhage than in the control group. the same alterations could be observed incubating adrenal tiss ...1975179800
radiometric-high-performance liquid chromatographic assay for nicotine and twelve of its metabolites.a sensitive, reproducible radiometric-high-performance liquid chromatographic assay has been developed to measure concentrations of nicotine and twelve of its metabolites in biological fluids. following administration of nicotine ([2-14c]pyrrolidine) to rats, the assay was used in a pharmacokinetic investigation.19873667778
high mutagenic activity of 3-azido-1,2-propanediol (azidoglycerol, ag) in strain d7 of saccharomyces cerevisiae.3-azido-1,2-propanediol (azidoglycerol, ag) showed a high mutagenicity in strain d7 of saccharomyces cerevisiae. at 5 mm it increased the spontaneous frequency of isoleucine revertants 3500 times and the frequency of gene convertants 3000 times during 24 h of growth, reducing the growth rate to 30%. in non-growth conditions, treatment with 150 mm of ag for 3 h reduced cell survival to 60% and enhanced the frequency of isoleucine revertants 490 times and tryptophan-independent convertants 50 time ...19873553915
hippocampal evoked potentials and eeg changes during classical conditioning in the rat.hippocampal evoked potentials (eps) and eeg responses were studied in rats, using a classical conditioning paradigm (water, us), with a spatially discontiguous cs-us arrangement in order to separate the cs and goal-related responses. in early training, when the orienting score was high, the tone cs, instead of eliciting a definite ep, usually reset hippocampal theta activity in phase, i.e. theta rhythm became time-locked to cs. with further training, orienting activity (ori) decreased to the pre ...197988362
immunologic studies of native and modified human factor viii/von willebrand factor.factor viii/von willebrand factor (fviii/vwf) is a glycoprotein with a molecular weight greater than one-million daltons. two activities are associated with this large molecule: fviii procoagulant activity and vwf activity. incubation of fviii/vwf with proteolytic enzymes causes rapid inactivation of the fviii procoagulant activity but has little effect on the vwf activity or antigenicity. in an attempt to gain insight into the structural features required for these two activities, antisera were ...197988237
potentiating effect of nitrate and other anions on contraction in vascular smooth muscle. 197887173
administration of thyrotropin releasing hormone (trh) to rats releases dopamine in n. accumbens but not n. caudatus. 1979105304
formation of lithogenic bile in man. 19734362764
characterization of phospholipase b of culex pipiens fatigans.phospholipase b has been found in the mosquito culex pipiens fatigans, and some of its properties have been studied. the enzyme had a high optimum temperature (45 degrees c) and broad alkaline ph optimum (8-9). it was inactive toward diacylphospholipids, and hydrolyzed lysolecithin at a higher rate than lysophosphatidyl ethanolamine. the enzyme was heat labile, but lysolecithin protected it against heat inactivation. phosphatidyl ethanolamine, phosphatidyl choline, deoxycholate, fe(+++), and hg( ...19694390654
[cat-scratch disease and disease caused by bartonella (rochalimaea)].the aetiology of cat scratch disease remains controversial since both afipia felis and bartonella (rochalimaea) henselae have been isolated from diseased lymph nodes. bartonella henselae, bartonella (rochalimaea) quintana and bartonella (rochalimaea) elizabethae cause endocarditis and bartonella bacilliformis cause septicemia (oroya's fever) in non-immunocompromized patients, and bartonella henselae and bartonella quintana cause fever, bacillary angiomatosis, and visceral peliosis in human immun ...19957534931
use of bartonella antigens for serologic diagnosis of cat-scratch disease at a national referral center.bartonella henselae (formerly the genus rochalimaea) has recently been isolated from patients with cat-scratch disease and their cats, and since september 1992 the centers for disease control and prevention has offered an indirect fluorescent antibody assay for bartonella-specific antibody.19957542443
bartonella strains in small mammals from dhaka, bangladesh, related to bartonella in america and europe.ecological and bacteriologic observations of small mammals captured in dhaka, bangladesh, indicated that bartonella infections occurred in high prevalence among lesser bandicoot rats (bandicota bengalensis), black rats (rattus rattus), and house shrews (suncus murinus). sequence analysis of the citrate synthase gene of bartonella isolates showed that small mammals in bangladesh harbored a diverse assemblage of strains. some cultures were genetically related to bartonella elizabethae, a species i ...200717827381
naturally occurring diatomaceous pneumoconiosis in sub-human primates. 197896157
proposals to unify the genera bartonella and rochalimaea, with descriptions of bartonella quintana comb. nov., bartonella vinsonii comb. nov., bartonella henselae comb. nov., and bartonella elizabethae comb. nov., and to remove the family bartonellaceae from the order rickettsiales.dna hybridization data (hydroxyapatite method, 50 to 70 degrees c) indicate that rickettsia prowazekii, the type species of the type genus of the family rickettsiaceae, is substantially less closely related to rochalimaea species than was previously thought. the levels of relatedness of rickettsia prowazekii to rochalimaea species and to bartonella bacilliformis under optimal conditions for dna reassociation were 0 to 14%, with 25.5% or greater divergence in related sequences. when stringent rea ...19938240958
comparison of partial citrate synthase gene (glta) sequences for phylogenetic analysis of bartonella species.nucleotide base sequence data were obtained for a 940-bp fragment of the citrate synthase-encoding gene (glta) of representatives of the eight validly described bartonella species and seven uncharacterized bartonella strains obtained from small mammals. complete 16s rrna gene sequences were also determined for the uncharacterized strains, and these sequences revealed that each strain had a unique sequence which was very similar to the sequences of the previously recognized bartonella species. a ...19968863415
[effect of aflatoxin b 1 on respiration and oxidative phosphorylation in the rabbit. ii. research on cardiac and renal mitochondria].the effect of various concentrations of aflatoxin b1 (ab1) is studied "in vitro" on heart (hm) and kidney mitochondria of rabbit (km). ab1 inhibits (4 x 10(-4)m) the respiratory rate up to a maximum 50-35% in hm and 28-35% in km by glutamate and succinate as substrates respectively, but it does not uncouple oxidative phosphorylation nor does it inhibit site iii (ascorbate + tmpd). the inhibited site appears to be between cytochromes b and c (c1). ab1 seems to be easily transported across heart m ...1979548060
rochalimaea elizabethae sp. nov. isolated from a patient with endocarditis.a rochalimaea-like organism (strain f9251) was isolated from a patient with endocarditis after blood drawn for culture before antimicrobial therapy was subcultured onto blood and chocolate agars and incubated for 2 weeks in 5% co2. the strain was phenotypically similar to known rochalimaea species. the cellular fatty acid composition of strain f9251 was close to but distinct from those of the three known rochalimaea species and was most similar to that of r. vinsonii. labeled dna from strain f92 ...19937681847
bartonella tribocorum sp. nov., a new bartonella species isolated from the blood of wild rats.two bartonella strains from blood of two wild rats (rattus norvegicus) living in a rural environment were isolated. these strains were distinct from all previously known bartonella species based on phenotypic and genotypic characteristics. this new species is distinguished by its trypsin-like activity, the absence of the ability to hydrolyse proline and tributyrin, its 16s rrna and citrate synthase gene sequences and by whole-dna hybridization data. this new species, for which the name bartonell ...19989828434
rats of the genus rattus are reservoir hosts for pathogenic bartonella species: an old world origin for a new world disease?bartonella species were isolated from the blood of 63 of 325 rattus norvegicus and 11 of 92 rattus rattus from 13 sites in the united states and portugal. infection in both rattus species ranged from 0% (e.g., 0/87) to approximately 60% (e.g., 35/62). a 337-bp fragment of the citrate synthase (glta) gene amplified by polymerase chain reaction was sequenced from all 74 isolates. isolates from r. norvegicus were most similar to bartonella elizabethae, isolated previously from a patient with endoca ...199910353885
in vitro susceptibilities of rickettsia and bartonella spp. to 14-hydroxy-clarithromycin as determined by immunofluorescent antibody analysis of infected vero cell monolayers.the in vitro susceptibilities of rickettsia akari, rickettsia conorii, rickettsia prowazekii, rickettsia rickettsii, bartonella elizabethae, bartonella henselae and bartonella quintana to different concentrations of clarithromycin, 14-hydroxy-clarithromycin (the primary metabolite of clarithromycin) and tetracycline in vero cell cultures, were determined by enumeration of immunofluorescently-stained bacilli. the extent of antibiotic-induced inhibition of foci was recorded for each dilution of an ...200010702548
preganglionic neurons in the sacral spinal cord of the rat: an hrp study. 197986176
a bacteriophage-like particle from bartonella bacilliformis.bartonella bacilliformis and bartonella henselae, the respective agents of oroya fever and cat-scratch disease in humans, are known to produce bacteriophage-like particles (blps) that package 14 kbp segments of the host chromosome. data from this study suggest that other bartonella species including bartonella quintana, bartonella doshiae and bartonella grahamii also contain similar blps, as evidenced by the presence of a 14 kbp extrachromosomal dna element in their genomes, whereas bartonella e ...200010746763
molecular phylogeny of the genus bartonella: what is the current knowledge?species of the genus bartonella are involved in an increasing variety of human diseases. in addition to the 14 currently recognized species, several bartonella strains have been recovered from a wide range of wild and domestic mammals in europe and america. such a high diversity of geographic distributions, animal reservoirs, arthropod vectors and pathogenic properties makes clarification of our knowledge about the phylogeny of bartonella species necessary. phylogenetic data have been inferred m ...200111410341
evidence of rodent-associated bartonella and rickettsia infections among intravenous drug users from central and east harlem, new york city.we tested serum samples collected in 1997 and 1998 from a cohort of 204 injection drug users (idus) recruited from central and east harlem, new york city, new york, for antibodies reactive with seven rickettsial or bartonella spp. antigens. rodent-associated bartonella elizabethae and rickettsia akari were the primary etiologic agents of interest. the testing panel also included bartonella henselae, bartonella quintana, rickettsia prowazekii, rickettsia rickettsii, and rickettsia typhi. the high ...200111791987
human seroreactivity against bartonella species in the democratic republic of congo.to assess the presence and identity of bartonella species in a pool of human blood samples from drc congo.201121771478
genetic and ecologic characteristics of bartonella communities in rodents in southern china.ecologic and bacteriologic observations of small mammals captured in yunnan province in the people's republic of china indicated that bartonella infections occurred at a high prevalence among some rodent species. sequence analyses of the citrate synthase genes of these bartonella demonstrated that rodents in this region harbored a diverse assemblage of strains. the bartonella isolates obtained from apodemus, eothenomys, and rattus typically clustered separately by genus of rodent host. cultures ...200212201602
antibodies to bartonella species in inner-city intravenous drug users in baltimore, md.bartonella quintana has recently been associated with homeless alcoholic men. both b quintana and bartonella henselae have been shown to be opportunistic pathogens of people with acquired immunodeficiency syndrome. the reservoirs and modes of transmission of these infections are incompletely known.19968944742
leber's neuroretinitis in a patient with serologic evidence of bartonella elizabethae. 19989654422
phylogenetic classification of bartonella species by comparing groel sequences.bartonella is a bacterial genus classified in the alpha-proteobacteria on the basis of 165 rdna sequence comparison. the highly conserved heat-shock chaperonin protein, groel, has proved to be a valuable resolving tool to classify ten bartonella species. the groel gene was amplified and sequenced from ten bartonella isolates: bartonella alsatica, bartonella vinsonii subsp. arupensis, bartonella taylorii, bartonella tribocorum, bartonella birtlesii, bartonella henselae marseille (urlly8), b. hens ...200211837299
deficiency of the ninth component of complement in man.the studies of serum from a case with c9 (the ninth component of complement) deficiency are described. a 29-year-old woman in good health was found to have low serum complement levels (ch50). c9 of her serum was undetectable by the hemolytic assay and by the immunochemical analysis but all other components were normal. it was demonstrated that low ch50 of her serum was due to the hemolysis of the sensitized sheep erythrocytes (ea) by the complement components from c1 to c8.197995812
bartonella henselae and bartonella elizabethae as potential canine pathogens.bartonella henselae or bartonella elizabethae dna from edta-anticoagulated blood samples obtained from four dogs was amplified and sequenced. the results showed that b. elizabethae should be added to the list of bartonella species (i.e., b. vinsonii subsp. berkhoffii, b. henselae, and b. clarridgeiae) that are currently recognized as infectious agents in dogs. furthermore, these results may have potential zoonotic implications, particularly if dogs can serve as a previously unrecognized reservoi ...200212454170
prevalence study of antibody to ratborne pathogens and other agents among patients using a free clinic in downtown los angeles.norway rats (rattus norvegicus) are hosts for various microbes. homeless people who have contact with rats may be at risk of infection by them. the los angeles county department of health services initiated a seroepidemiologic study among patients who used a free clinic in downtown los angeles; 200 serum specimens obtained for other routine assays were tested for antibodies to ratborne pathogens and other agents. the seroprevalence of antibody to hepatitis e virus in this population was 13.6%; t ...200212447746
[the adrenergic innervation of the thoracic lymphatic duct in dogs in postnatal ontogeny].using histochemical fluorescence technique, studies have been made on the adrenergic innervation of the wall of the thoracal lymphatic duct in postnatal development of puppies. adrenergic fibers were found in the adventitial layer of the duct. during postnatal development of the animals, adrenergic innervation of this duct becomes more perfect, reaching the level of adult animals to the age of 2-3 months.197995857
a survey of zoonotic pathogens carried by norway rats in baltimore, maryland, usa.norway rats (rattus norvegicus) carry several zoonotic pathogens and because rats and humans live in close proximity in urban environments, there exists potential for transmission. to identify zoonotic agents carried by rats in baltimore, maryland, usa, we live-trapped 201 rats during 2005-2006 and screened them for a panel of viruses, bacteria, and parasites. antibodies against seoul virus (57.7%), hepatitis e virus (hev, 73.5%), leptospira interrogans (65.3%), bartonella elizabethae (34.1%), a ...200717224086
bartonella dna in the blood and lymph nodes of golden retrievers with lymphoma and in healthy controls.although lymphoma is the most common neoplastic process reported in dogs, its precise etiology is unknown. golden retrievers are more likely to develop lymphoma, suggesting a breed predisposition; however, other factors, including environment, immunity, and infection, are likely contributors to oncogenesis.200818289294
molecular evidence for bartonella spp. in cat and dog fleas from germany and france.nine hundred and fifty-two fleas were collected from 148 cats and 133 dogs at 18 widely distributed geographic locations in germany and france and examined for the presence of six different bartonella spp. (bartonella bacilliformis, bartonella clarridgeiae, bartonella elizabethae, bartonella henselae, bartonella quintana, bartonella vinsonii subsp. berkhoffii) by pcr. thirty-five specimens (3.7%) tested positive for either b. henselae (14 positive fleas) or b. clarridgeiae (21 positive fleas). d ...200818489542
isolation of bartonella species from rodents in taiwan including a strain closely related to 'bartonella rochalimae' from rattus norvegicus.an increasing number of bartonella species originally isolated from small mammals have been identified as emerging human pathogens. during an investigation of bartonella infection in rodent populations carried out in taiwan in 2006, a total of 58 rodents were tested. it was determined that 10.3 % (6/58) of the animals were bartonella bacteraemic. after pcr/rflp analysis, four isolates were identified as bartonella elizabethae and one isolate as bartonella tribocorum. however, there was one speci ...200819018019
epidemiology of bartonella infection in rodents and shrews in taiwan.during the period of august 2002 and november 2004, an epidemiological investigation for bartonella infection was conducted in small mammals in taiwan. using whole blood culture on chocolate agar plates, bartonella species were successfully isolated from 41.3% of the 310 animals tested. the isolation rate of bartonella species varied among different animal species, including 52.7% of the 169 rattus norvegicus, 28.6% of the 126 sucus murinus, 10% of the 10 rattus rattus and 66.7% of the three rat ...201019538457
isolation and genetic characterization of a bartonella strain closely related to bartonella tribocorum and bartonella elizabethae in israeli commensal rats.ten bartonella isolates were cultured from blood drawn from black rats (rattus rattus) captured in the tel aviv area. genetic characterization included amplification and sequencing of five gene fragments including the ribc, rpob, 16s, groel, and glta and the 16s-23s intergenic spacer region. sequence comparisons showed that all 10 isolates were identical in all genes studied comprising a total of 3,873 bp analyzed. the sequences of each of the partial genes analyzed indicated a high sequence sim ...200919556567
prevalence and genetic heterogeneity of bartonella strains cultured from rodents from 17 provinces in thailand.to study the distribution and diversity of bartonella in rodents from thailand, 330 rodents belonging to 13 species were tested. the majority (80.6%) of rodents examined belonged to the genus rattus. bartonellae were cultured from 41.5% of the rodents with a wide range of prevalence by host species and regions. sequencing of glta revealed diverse bartonella strains. bartonellae from rattus spp. belonged to 23 variants and clustered with bartonella coopersplainensis, bartonella elizabethae, barto ...200919861616
variability of bartonella genotypes among small mammals in spain.in order to study which bartonella genotypes are circulating among small mammals in spain, we analyzed the spleens of 395 animals from three different areas-247 animals from the basque country (northern spain), 121 animals from catalonia (northeastern spain), and 27 animals from madrid (central spain)-by a triplex pcr combined with a reverse line blot previously described by our group. the prevalence of bartonella was 26.8% (106/395), and in 4.8% (19/395) of the animals more than one bartonella ...201020935117
bartonella infection in shelter cats and dogs and their ectoparasites.abstract mainly through vector transmission, domestic cats and dogs are infected by several bartonella spp. and represent a large reservoir for human infections. this study investigated the relationship of prevalences of bartonella infection in shelter dogs and cats and various ectoparasite species infesting them (fleas, ticks, and lice). moreover, relationships between bartonella infection and animal gender and age and presence of ectoparasites were analyzed. blood samples were collected from 1 ...201021142966
identification of novel bartonella spp. in bats and evidence of asian gray shrew as a new potential reservoir of bartonella.many studies indicated that small mammals are important reservoirs for bartonella species. using molecular methods, several studies have documented that bats could harbor bartonella. this study was conducted to investigate the relationship of bartonella spp. identified in bats and small mammals living in the same ecological environment. during may 2009 and march 2010, a total of 102 blood specimens were collected. by whole blood culture and molecular identification, a total of 6 bats, 1 rodent a ...201122005177
bartonellae of the namaqua rock mouse, micaelamys namaquensis (rodentia: muridae) from south africa.the aim of this study was to determine bartonella prevalence and diversity in namaqua rock mice, micaelamys namaquensis, a species endemic to south africa, which can attain pest status. a total of 100 heart samples collected monthly from march to december were screened for bartonella genome presence using three primer sets targeting the citrate synthase (glta) gene, the nadh dehydrogenase gamma subunit (nuog) gene and the rna polymerase β-subunit-encoding gene (rpob). an overall prevalence of 44 ...201122204791
detection and characterization of feline bartonella henselae in the czech republic.the aims of the study were to characterize isolates of bartonella henselae and to determine the prevalence of bacteremic domestic cats in urban and suburban parts of prague, czech republic. five (18%) gram-negative fastidious bacterial single-cat isolates were recovered from 27 hemocultures incubated without previous freezing. four of these isolates originated from flea infested stray cats (n=6) and one from a shelter cat without any ectoparasites (n=21). none of the 34 previously frozen specime ...200312695049
bartonella spp. antibodies in forensic samples from swedish heroin addicts.a high frequency of bartonella elizabethae seropositivity (39%) was recorded among intravenous heroin addicts in stockholm, sweden, who died from a lethal injection. some of the b. elizabethae-seropositive individuals also had antibodies to b. henselae houston-1, b. grahamii, and b. quintana, but none had antibodies to b. henselae marseille or b. vinsonii subsp. vinsonii. hepatitis was a frequent finding but no case had peliosis hepatitis. there was no case of endocarditis, but in three persons ...200312860665
bartonella infections: diagnostic and management issues.bartonella species are emerging pathogens. renewed interest in this group of bacteria has been highlighted by the recent description of new species, which are pathogenic for humans (bartonella elizabethae and bartonella clarridgeae), and their association with an increasing number of clinical manifestations, the more prevalent being cat scratch disease, bacillary angiomatosis, and culture-negative endocarditis.199817033388
[the lice of the gerbils of tajikistan].2606 gerbils of four species from tajikistan were examined. on them there were found over 14 thousand sucking lice of 10 species, four of which are typical to gerbils. hoplopleura merionidis ferris is a mongolian-turkestan species, which in central asia parasitizes meriones meridianus pallas and m. unguiculatus milne-edw. and in middle asia--m. meridianus and m. erythrourus gray, seldom m. tamariscinus pallas. polyplax chinensis ferris, a parasite of m. meridianus, is a mongolian-turkestan speci ...197995816
molecular detection of rickettsia felis, rickettsia typhi and two genotypes closely related to bartonella elizabethae.a total of 56 fleas were collected from mice, rats, and one hedgehog in national parks of mainland portugal and the madeira island. all fleas were tested for the presence of bacteria of the genera rickettsia and bartonella using pcr assays. in fleas from mainland portugal, we detected rickettsia felis in one archaeopsylla erinacei maura flea and in one ctenophtalmus sp. in five leptopsylla segnis fleas taken from rats in the madeira island, we identified rickettsia typhi. in addition, in four fl ...200617038702
urban zoonoses caused by bartonella, coxiella, ehrlichia, and rickettsia species.the last half of the 20th century witnessed an increase in the occurrence and recognition of urban zoonoses caused by members of the genera bartonella, coxiella, ehrlichia, and rickettsia, all traditionally considered to be members of the family rickettsiaceae. in recent years, new human pathogens (bartonella elizabethae, bartonella henselae, and rickettsia felis) have been recognized in urban environments. other newly recognized pathogens (ehrlichia chaffeensis and ehrlichia phagocytophila in t ...200112653141
comments on references to the american board of psychiatry and neurology in an article. 20023369584
control of thyroglobulin synthesis and secretion (second of two parts). 200188013
adult respiratory-distress syndrome in salicylate intoxication. 200187755
selective vestibular neurectomy through the posterior fossa in ménière's disease.the authors report on a series of 18 patients operated through the posterior fossa approach for selective vestibular neurectomy. the indication for surgery consisted of intractable vertigo in cases of ménière's disease. results were excellent with a 94% cure of vertigo and 100% improvement. postoperative hearing results were good with 78% of patients maintaining their discrimination score and 94% their pure tone average threshold. the results and the advantages of this approach are discussed and ...20073225882
comparative efficacy of calcium antagonist drugs in the prophylaxis of migraine. 20133908401
x-associated immunocompetence. 199984980
serum alkaline phosphatase activity in acrodermatitis enteropathica: an index of the serum zinc level.a significant positive correlation between serum zinc and serum alkaline phosphatase levels was demonstrated in four patients suffering from acrodermatitis enterophathica for which they received oral zinc sulphate therapy. in one of the male patients a significant inverse relation between serum zinc and serum copper was found.199984482
general-practice training, exeter style. 200087562
comparison of metal complexes between depyruvamide bleomycin and bleomycin: an important effect of axial donor on metal coordination and oxygen activation. 200088941
effect of radiotherapy on the neutrophil and the lymphocyte enzymatic equipment and serum immunoglobulins in patients with cancer of the larynx.in 30 patients with cancer of the larynx, aged 40 to 70 years, treated by radiotherapy 6 to 9 years ago the decreased activity of neutrophil beta-glucuronidase and n-acetyl-beta-glucosaminidase accompanied by a decrease of absolute count of enzyme-positive cells was noted. numbers of acid phosphatase-positive neutrophils were also decreased. moderate increase of the neutrophil alkaline phosphatase activity and of numbers of enzyme-positive cells was another observed feature. the main finding in ...200188387
a multi-gene analysis of diversity of bartonella detected in fleas from algeria.we report the molecular detection of several bartonella species in 44 (21.5%) of 204 fleas from algeria collected from 26 rodents and 7 hedgehogs. bartonella elizabethae and b. clarridgeiae were detected in the fleas collected on hedgehogs. bartonella tribocorum and b. elizabethae were detected in fleas collected from rats and mice, and sequences similar to an unnamed bartonella sp. detected in rodents from china were detected in rats as well as a genotype of bartonella closely related to barton ...201122153359
axonal transport of lipid in goldfish optic axons.after injection of labeled glycerol, choline, or serine into the eye of goldfish, labeled lipids were axonally transported along the optic nerve to the optic tectum. although the different precursors were presumably incorporated into somewhat different lipid populations, all three were approximately equally effective in labeling the lipids transported to the tectum, but the amount of transported material remaining in the nerve was different, being highest with choline and lowest with serine. the ...199985271
[irradiation combined with bleomycin. 5-year results with 27 o.r.l. epitheliomas (proceedings)]. 199985709
diarrhoeal diseases: perceptions and practices in nepal.a study undertaken in nepal collected information on believed causes of diarrhoea and traditional treatments. natural causes for diarrhoea were more frequently reported than supernatural causes, the most important being teething (75% of respondents reporting it to be a cause) followed by food considered to be 'cold' in the hindu ayurvedic classification (57.5%), stale food (52.5%), hot food (41%) and dirty water (38%). the terminology reported for dehydration however, indicates strong links with ...20092928835
prolonged control of increased intracranial pressure with glycerin. 20125049685
design and data quality of a mixed longitudinal study to elucidate the role of dietary calcium and phosphorus on bone mineralization in pre-, peri-, and postmenopausal women.the study design and data quality control of an ongoing study (10 yr duration) in a few hundred women are presented. good variables with respect to their longitudinal usefulness are: body weight, body height, and span-width. reasonable variables are the bone parameters of the radius (bmc, bw, and bmc/bw). poor variables are: dietary calcium and phosphorus intake, dietary calcium-to-phosphorus ratio, urinary calcium-to-creatinine ratio, urinary sodium-to-creatinine ratio, hematocrit, serum alkali ...20143962907
changes in renal size following intra-arterial administration of water-soluble contrast medium. 20154430589
chemotherapy in advanced gastric cancer: a controlled, prospective, randomised multi-centre study.seventy-six patients with advanced gastric adenocarcinoma were studied in a prospecitive, randmoised, controlled trial using vincristine, methotrexate, cyclophosphamide, and 5-fluorouracil in an initiation course and mitomycin-c with 5-fluorouracil as maintenance therapy. thirty-seven patients were inoperable and 39 had the primary tumour resected with histological evidence of residual disease. survival in the inoperable group was short and showed no significant difference between treated and co ...2004387542
overdose of cyclobenzaprine, the tricyclic muscle relaxant.a case of cyclobenzaprine (flexeril) overdose in a 31-year-old woman is presented. the treatment rendered was analogous to treatment protocols implemented for tricyclic overdose. a review of the pharmacology of cyclobenzaprine, as well as the management of patients who overdose on this drug, is presented.20072870671
[immunohistochemical study of the differentiation of the cephalic lobe of the adenohypophysis in chick embryos].it was shown by means of indirect immunofluorescence that acth appeared in the cephalic lobe of the chick embryo pituitary beginning from the 8th day of the development. a new tissue-specific antigen (a3) is revealed, which is localized in the cephalic lobe of adenohypophysis and becomes manifest at the 7th day of embryogenesis. quantitative analysis of acth and a3 localization in the cells of 11-day chick embryo adenohypophyses allows a conclusion that a3 is localized in corticotropic cells.200188969
[present state of conservative breast therapy in canada]. 20082746948
[thrombocytopenias. radioisotope studies. platelet survival studies]. 2002120271
the emergence of a health insurance system in a developing country: the case of south korea.in an attempt to understand the social forces and the economic and political conditions under which new social policies emerge in developing countries, this study outlines factors affecting the introduction of the health insurance system in south korea. the emergence of the south korean health insurance system was influenced by changing labor needs of the industrial sector, increasing social expectations, external and international pressures, increasing medical costs, and class conflict. these p ...20082600387
jaundice. clinical pearls and perils revisited.i recount some clinical "pearls and perils" to help reassess the contributions of abdominal ultrasound, cholangiography, needle biopsy of the liver, and laparoscopy. abdominal ultrasound demonstrates stones in the gallbladder in approximately 98% of cases, but in only 15% in the common bile duct, whereas computerized tomography scan reveals them in greater than or equal to 50%. on cholangiography a blood clot (in hemobilia) may closely resemble a common duct stone, as may spasm or tumor of the d ...20032958535
rural hospitals rely more on outpatient revenue. 20123391547
mallet fractures.contrary to our observations, reports in the literature maintain that only a third of mallet finger deformities are caused by intra-articular fractures of the posterior margin of the distal phalanx. as functional impairment sometimes remains after treatment, there is still much discussion as to the relative merits of conservative and surgical management of this lesion. this article presents 21 cases of mallet finger deformities with fracture of the distal phalanx, of which 17 received surgical t ...20123426323
basal metabolism of obese adolescents: inconsistent diet and exercise effects.effects of 20 wk of diet-plus-behavior (db) therapy or exercise-plus-diet-plus-behavior (edb) therapy on changes in basal energy expenditure (bee) were studied in 36 obese male and female adolescents. bee was assessed by open-circuit spirometry and body composition by hydrostatic weighing. dietary restriction was based on the dietary-exchange program. behavioral treatment included record-keeping, stimulus-control, and reinforcement techniques. edb therapy included 50 min/d, 3 d/wk of aerobics. a ...20123414571
vulvovaginal reconstruction following radical resections. 20123757340
[clinical use of the trh-tsh stimulation test with special reference to pediatric thyroid-gland diseases]. 199996623
chunking in recall of symbolic drawings. 199988658
histogenesis of malignant melanoma with an adjacent component of the superficial spreading type.there has been a world-wide exponential increase in the incidence of thin malignant melanoma. at the sydney melanoma unit, the proportion of patients diagnosed as having superficial spreading melanoma has more than doubled from 33% prior to 1960 to 78% during 1980-83. a study was made of the non-invasive component of malignant melanoma with an adjacent non-invasive component of the superficial spreading type in an attempt to elucidate the pathogenetic mechanisms involved in these changing trends ...20144047726
injury to the glenoid fossa.an illustrated case of fracture through the confines of the glenoid fossa by the mandibular condyle is presented. the mechanism of injury and postinjury sequelae of this rarely reported but frequently suspected occurrence are discussed and a treatment rationale proposed. the key to the diagnosis of this entity is an awareness of vector forces directed to the region of the glenoid fossa with or without evidence of subcondylar fracture.20143945692
[use of l-asparaginase in therapy with special reference to acute lymphatic leukemia]. 20154502507
trauma care: don't forget the patient. nursing grand rounds. 200188032
diagnosis of carrion's disease by direct blood pcr in thin blood smear negative samples.bartonella bacilliformis is the etiologic agent of carrion's disease. this disease has two well established phases, the most relevant being the so called oroya fever, in which b. bacilliformis infect the erythrocytes resulting in severe anemia and transient immunosuppression, with a high lethality in the absence of adequate antibiotic treatment. the presence of b. bacilliformis was studied in 113 blood samples suspected of carrion's disease based on clinical criteria, despite the absence of a po ...201424651298
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