selective decontamination of the digestive tract of syrian hamsters.conventional syrian hamsters colonized with aerobic gram-negative bacteria such as pasteurella pneumotropica and various enterobacteriaceae species were successfully and permanently freed from these microorganisms by oral treatment for 4 weeks with dihydrostreptomycin and 'orabase' premixed with appropriate antibiotics. concomitant oral treatment with dimetridazol for the elimination of intestinal flagellates was unsuccessful. during treatment the animals were maintained under germ-free isolatio ...197882636
self-mutilation in mice associated with otitis media.mutilation of the external ear and adjacent tissues was an enzootic problem in outbred mcr:(icr) breeder mice in a commercial colony. necropsy examination of affected and randomly selected, nonaffected adult breeder mice revealed a probable association of the cutaneous lesions with suppurative otitis media. several microorganisms, including mycoplasma pulmonis and pasteurella pneumotropica, were isolated from the tympanic bullae.19751095819
[phlegmon of the fore arm succeeding to a dog-bite : respective role of the miscellaneous bacteria involved in this mixed infection (author's transl)].the authors report a case of a severe mixed infection (phlegmon of the fore arm) succeeding to a dog bite. a complex flora has been isolated from this phlegmom : pasteurella multocida, pasteurella pneumotropica, streptococcus mitis, actinomyces sp., bacteroides melaninogenicus, and a gram- bacteria related to group ii j. the pathogeny of such diseases is discussed, dwelling in one hand on the part of synergistic development of these various germs and in the other hand on the part played by saliv ...197934886
characterization of some previously unclassified pasteurellaceae isolated from hamsters.bacteria isolated from purulent processes on the jaws of european hamsters (cricetus cricetus) and from intestinal inflammatory processes in syrian hamsters (mesocricetus auratus), bred as laboratory animals have been shown to be phenotypically similar but not identical with pasteurella pneumotropica. deoxyribonucleic acid (dna)-dna hybridization studies indicate that with one exception, the strains represent two new species of the family pasteurellaceae. in the absence of a close genomic relate ...19892808184
pasteurella pneumotropica: meningitis following a dog bite.a 38 year old man developed meningitis following a dog bite. pasteurella pneumotropica, usually an animal pathogen, was isolated from the cerebrospinal fluid. the patient made a complete recovery after antibiotic therapy. the relevant literature is reviewed.19902349182
acute painful cellulitis caused by a pasteurella pneumotropica-like bacterium in northern queensland. 19902314344
[epidemiologic evaluation of a sample of 91 rats (rattus norvegicus) captured in the sewers of lyon].91 rats captured in 1982 in the sewers of lyon (france) have been examined for the presence of some microorganisms implicated in infections transmissible to man, by direct examination, bacteriological culture or detection of specific antibodies. bacteriological results have shown a high proportion of carriers of yersinia enterocolitica and frederiksenii (29%), of pasteurella pneumotropica (29%), of staphylococcus aureus (53%), and of campylobacter jejuni (18%), a low proportion of carriers of sa ...19863532637
a dog bite wound infected with pasteurella pneumotropica.a case is described of a dog bite of a finger which was infected with pasteurella pneumotropica; it was successfully treated with amoxycillin.1977561881
chronic necrotizing mastitis in rats caused by pasteurella pneumotropica.sixty-one of 2500 f344 rats were observed to have one to three enlarged and firm mammary glands. pasteurella pneumotropica was isolated from all affected mammary glands. it was also routinely isolated from the feces of all cages and from the oral cavity of rats up to 6 weeks old, but not from the oral cavity of rats over 4 months of age. the organism was not isolated from clinically normal lactating mammary glands. histopathological diagnosis of affected glands was chronic necrotizing mastitis.1978682580
incidence of otitis media in cba/j and cba/caj mice.the inbred cba/j mouse has become a standard experimental animal for auditory study because of its lifelong good hearing. in a newly established mouse breeding colony that housed cba/j and cba/caj mice to reared as auditory subjects, otitis media frequently afflicted cba/j mice, reaching an incidence of 90% in animals greater than 400 days of age. otitis media was not found in cba/caj mice. three attempts to establish a colony that was free of otitis were unsuccessful. although the primary patho ...19921629038
[septicemia caused by pasteurella pneumotropica]. 19921488425
[a trial designed to obtain a specific pathogen free syrian hamster colony by administration of chemicals].conventional syrian hamsters, contaminated with giardia spp., spironucleus muris, trichomonas spp., pasteurella pneumotropica and pseudomonas aeruginosa were treated with chemicals in order to obtain specific pathogen free animals. hamsters kept in the laminar flow rack were treated orally with metronidazole several times to obtain a flagellate-free colony. after all flagellates had been eradicated, one pair of animals were kept in an isolator and mating was allowed to occur. when their offsprin ...19921387090
the masked rat. an x-ray induced mutant with chronic blepharitis, alopecia, and autosomal recessive mutation had been previously x-ray-induced in the rat and named the masked rat (genotype mk/mk). this study describes the mutant's appearance, histology, and microflora. the rat's eyelids were swollen, often to the point of closure, and its face was partially covered by a brownish crust, giving the mutant a mask-like appearance. the chronic blepharitis was also accompanied by alopecia that appeared as bare patches across the mutant's back. pasteurella pneumotropica was fou ...19761262697
an eye infection in laboratory mice associated with pasteurella pneumotropica. 19751160334
enzyme-linked immunosorbent assay and immunoblot analysis of the immunoglobulin g response to whole-cell and lipooligosaccharide antigens of pasteurella pneumotropica in laboratory mice with latent pasteurellosis.the immunoglobulin g (igg) response to whole-cell and lipooligosaccharide (los) antigens of pasteurella pneumotropica was evaluated in mice with latent pasteurellosis by enzyme-linked immunosorbent assay (elisa) and immunoblots. antibodies to cell wall proteins of p. pneumotropica also reacted with several protein antigens from isolates of actinobacillus spp. and other pasteurellae. conversely, antibodies to los antigens of p. pneumotropica demonstrated no cross-reactivity with loss of other pas ...19892584371
[mixed infection of albino rats with pasteurella pneumotropica and a new pneumotropic pasteurella species]. 1977888604
septicaemia due to pasteurella pneumotropica.the literature concerning pasteurella pneumotropica infection in animals and man is briefly reviewed and a case presented in which the organism was the cause of septicaemia in a patient receiving chemotherapy for myeloid leukaemia. bacteriological findings are recorded and compared with those of other authors.19734352465
the biochemical and cultural characteristics of pasteurella pneumotropica. 1977859377
[the genetic classification of the pasteurella pneumotropica complex].pasteurella pneumotropica with its biotypes jawetz and heyl are the most common bacterial pathogens associated with diseases in rodents. 23 p. pneumotropica biotype jawetz, biotype heyl and p. pneumotropica-like rodentia isolates have been investigated phenotypically by characterization of their micromorphology and biochemical fermentation reactions. the taxonomic position within the family pasteurellaceae has been examined by dna:dna hybridisation (optical method). it could be shown that p. pne ...19911898324
an enzyme-linked immunosorbent assay for detection of chronic subclinical pasteurella pneumotropica infection in mice.serum samples from seventy-five, 3- to 12-week-old and 16 retired breeder male swiss mice from a conventional colony with enzootic chronic subclinical pasteurella pneumotropica infection were tested by enzyme-linked immunosorbent assay (elisa) and western blots for igg antibodies to whole cell (wc) and lipooligosaccharide (los) antigens of p. pneumotropica. in 3- to 12-week-old mice, serum antibody levels to los exceeded those to the wc preparation. western blots of sera from mice in this age gr ...19911719273
the bacterial flora of the female rat genital tract.a study of the genital microflora in virgin female rats of reproductive age has demonstrated that alpha and nonhemolytic streptococci, pasteurella pneumotropica, diphtheroid bacilli, staphylococcus epidermidis, and proteus mirabilis are the predominant genital organisms. the ph of the rat vagina was demonstrated to be near neutrality. it is suggested that the higher ph in the rat vagina as compared to the human vagina may account for some of the differences between human and rat genital microflo ...1976768992
variation in pasteurella pneumotropica. 19744605431
treatment of pasteurella pneumotropica abscesses in nude mice (nu/nu). 1978732265
abortion in mice associated with pasteurella pneumotropica.pasteurella pneumotropica was isolated from the uteri, fetuses, lungs, and spleens of aborting swiss carworth mice. male mice in the colony carried p. pneumotropica in pharynges, testes, and seminal vesicles. normal pregnant and nongravid females carried p. pneumotropica in the eye of 1 and in the uteri of 4 of 11. pregnant mice from another colony did not abort when injected with p. pneumotropica. necrotizing and suppurative metritis was found among aborting females with p. pneumotropica infect ...1978701461
role of pasteurella pneumotropica and mycoplasma pulmonis in murine pneumonia.pneumonia caused by mycoplasma pulmonis and pasteurella pneumotropica was studied in conventional, specific pathogen-free (spf), and germ-free mice. when p. pneumotropica was serially passed in conventional mice, m. pulmonis, as well as p. pneumotropica, was recovered from mice with gross lesions. when m. pulmonis was serially passed in conventional mice, both organisms were recovered. spf mice given a nasal instillation of m. pulmonis alone, p. pneumotropica alone, or a combination of the two d ...19694884818
rederivation of inbred strains of mice by means of embryo transfer.embryo transfers were performed to rederive six inbred strains of mice, a/he, balb/cbyj, balb/c lac,, c57bl/6j and dba/2j. the aim was to determine whether it is possible to eliminate pathogens like mouse hepatitis virus (mhv) and pasteurella pneumotropica (p.p.). the embryos were collected, handled and transferred into the oviduct of day one pseudopregnant spf surrogate mothers under aseptic conditions. in 40.5% of the transfers, embryos developed to term. with respect to surrogate ...19882851686
the use of a simple barrier system to exclude murine pathogens.a simple barrier system was used successfully to exclude mycoplasma pulmonis and sendai virus from a conventional mouse room. 49 weeks after introduction of the barrier system of management pasteurella pneumotropica was first isolated from animals in the room.1977190466
alteration of the pathogenicity of pasteurella pneumotropica for the murine lung caused by changes in pulmonary antibacterial activity.pasteurella pneumotropica is a potential pulmonary pathogen in mice. in healthy animals, this organism was killed rapidly by the normal function of the intrapulmonary phagocytic defense mechanisms. impairment of this bactericidal activity by the acute renal failure of nephrectomy resulted in multiplication of the pasteurella in the lung, both when the animals were nephrectomized first and then infected, and when the animals were infected first and nephrectomized several hours after the infection ...19676025449
pasteurella pneumotropica as the causal organism of abscesses in the masseter muscle of mice. 1976933462
antigenic characterization of pasteurella pneumotropica isolated from mice and rats.antigenic characterization of p. pneumotropica derived from mice and rats were serologically investigated by use of hyperimmune rabbit sera against mouse strain m 1 and rat strain r 1 and absorbed sera m-1 and r-1 which were prepared by absorbing anti-m 1 serum with strain r 1 and anti-r 1 serum with strain m 1, respectively. all of 13 mouse strains employed were agglutinated with both anti-m 1 and anti-r 1 sera, but their agglutination titers with anti-m 1 serum were usually higher than those w ...19846205886
[nitrofurantoin-test for the differentiation of bordetella bronchiseptica (author's transl)].bordetella bronchiseptica is primarily resistant against nitrofurantoin (mic greater than 200 mug/ml), and this feature can be used for the differentiation of the organism from other gram-negative coccobacteria. nitrofurantoin paper disks (300 mug) failed to affect the growth of 150 strains of b. bronchiseptica isolated from different animal hosts, but they produced marked inhibition zones in the cultures of the followingspecies: pasteurella multocida, pasteurella pneumotropica, pasteurella haem ...1975809944
pasteurella pneumotropica in rabbits from a "pasteurella-free" production colony.pasteurella pneumotropica was isolated from the nasopharyngeal area of two of five rabbits obtained from a "pasteurella-free" production colony. no evidence of disease was observed in these rabbits during clinical and necropsy examinations.19836227773
a shift from acute to chronic spontaneous pyelonephritis in male mm mice associated with a change in the causal micro-organisms.proteus mirabilis was the predominant cause of acute diabetes-associated pyelonephritis occurring spontaneously in male mm mice until they were segregated in a new environment. thereafter pasteurella pneumotropica and streptococcus faecalis emerged collectively as the most common causal organisms, the pyelonephritis became more chronic and proteus mirabilis isolates from faeces and urine produced atypical non-swarming colonies on blood agar plates. this did not account for the reduced pathogenic ...19883127633
effect of sequential inoculations of sendai virus and pasteurella pneumotropica in mice. 19744361816
lung lysophospholipase activity in specific-pathogen-free rats infected with pasteurella pneumotropica or mycoplasma pulmonis.the effects of pasteurella pneumotropica and mycoplasma pulmonis infections in specific-pathogen-free rats were studied to determine whether or not bacterial infections could cause an increase in rat lung lysophospholipase activity and/or changes in bone marrow eosinophil levels. lung lysophospholipase activity levels of m. pulmonis-infected rats were elevated with increasing infection dosages, but enzyme levels were not accompanied by a lung tissue eosinophilia or an increase in bone marrow eos ...1978153332
chronic sialodacryoadenitis virus (sdav) infection in athymic rats.sialodacryoadenitis virus (sdav) was detected in athymic rats subcutaneously implanted with human tumor cell lines. clinical signs included sneezing, dyspnea, weight loss and death. necropsy revealed both upper and lower respiratory tract disease from which staphylococcus aureus, pasteurella pneumotropica and pseudomonas aeruginosa were recovered. histopathological changes consisted of suppurative rhinitis and bronchopneumonia. lesions characteristic of sdav infection were found in lacrimal and ...19911849581
effect of oestrogen on pasteurella pneumotropica in rat vagina.the effects of ovarian hormones on the vaginal population of pasteurella pneumotropica in rats were investigated. specified-pathogen-free adult female wistar-imamichi rats with a 4 day oestrous cycle were inoculated with p. pneumotropica in the vagina. cyclic changes in the vaginal population of p. pneumotropica were not observed in ovariectomized rats and the bacterial population was at a similar level to that at normal dioestrus. administration of oestrogen to ovariectomized rats caused an inc ...19863795854
modulation of pulmonary defense mechanisms by acute exposures to nitrogen dioxide.the effect of acute exposures to no2 on the antibacterial defenses of the murine lung was assessed following inhalation challenges with staphylococcus aureus, proteus mirabilis, and pasteurella pneumotropica. animals were challenged with the bacteria and exposed for 4 hr to increasing concentrations of no2 after which pulmonary bactericidal activity was quantitated. with s. aureus pulmonary antibacterial defenses were suppressed at no2 levels of 4.0 ppm and greater. exposure to 10.0 ppm enhanced ...19873803338
[infectious endocarditis caused by rare germs. review of the literature apropos of 2 cases].the authors report two new cases of endocarditis secondary to exceptionnally encountered germs: one to pasteurella pneumotropica, the other ascribed to leptospira ictero-haemorragiae, on serologic criteria. concerning these two cases, they propose to take a census of rare germs, from a detailed study of the literature. among more than 5,000 cases of endocarditis published after 1944, are considered as rare germs those causing a disease in less than one p. cent of the cases. this purely "mathemat ...19873827160
a numerical taxonomic study of actinobacillus, pasteurella and yersinia.a numerical taxonomic study of strains of actinobacillus, pasteurella and yersinia, with some allied bacteria, showed 23 reasonably distinct groups. these fell into three major areas. area a contained species of actinobacillus and pasteurella: a. suis, a. equuli, a. lignieresii, p. haemolytica biovar a, p. haemolytica biovar t, p. multocida, a. actinomycetemcomitans, 'p. bettii', 'a. seminis', p. ureae and p. aerogenes. also included in a was a composite group of pasteurella pneumotropica and p. ...19853840837
molecular characterization of antibodies bearing id-460. i. the structure of two highly homologous vh genes used to produce idiotype positive immunoglobulins.the heavy chain immunoglobulin genes encoding a variety of antibodies specific for dnp or pasteurella pneumotropica and bearing the dominant idiotype of mopc 460, id-460, were cloned and sequenced. the vh genes encoding the m460 and d35 (dnp binding) antibodies were found to be homologous but not identical to the vh gene encoding the lb8 (p. pneumotropica binding) monoclonal antibody. two of at least eight genes in the vh460 cross-hybridizing gene family can encode id-460 positive antibodies. th ...19863081634
pasteurella pneumotropica: cultural and biochemical characteristics, and its association with disease in laboratory animals. 19654222095
the pathology and pathogenesis of bordetella bronchiseptica and pasteurella pneumotropica infection in conventional and germfree rats. 19724345304
osteomyelitis of the heel with pasteurella pneumotropica: a case report.a rare case of pasteurella pneumotropica occurring in a polymicrobial anaerobic osteomyelitis of the heel is presented. the natural history, predisposing conditions, treatment, and postoperative care are presented. surgical excision of the infected portion of the calcaneus, appropriate antibiotics, and lift with proper supporting heel cup all aided in returning the patient to her normal daily activities.19863710325
postcopulatory genital grooming in male rats: prevention of sexually transmitted infections.prevention of postcopulatory genital grooming in male rats increased the likelihood that they would be genitally infected with a marker microorganism (staphylococcus aureus) inoculated previously into the vagina of female rats. male as well as female rat saliva was found to have very minimal bactericidal effects on the marker organism indicating that physical washing during postcopulatory grooming can prevent the transmission of infectious organisms. saliva of both male and female rats, however, ...19873432385
embryonic death in pregnant rats owing to intercurrent infection with sendai virus and pasteurella pneumotropica.during an outbreak of sendai virus infection in a colony of rats used for embryo production, severe lung lesions due to secondary colonization of the rat lungs with pasteurella pneumotropica were noted. the effect on pregnancy was to cause embryonic death and resorption, leaving a deciduoma with trophoblastic giant cells as the only embryonic remnants. up to 30% of fetuses in each pregnant animal were affected at the time of severe maternal lung lesions. heavy growths of pasteurella pneumotropic ...19882832656
an enzyme-linked immunosorbent assay (elisa) for the detection of antibodies to pasteurella pneumotropica in murine elisa for the detection of class specific igg antibodies to pasteurella pneumotropica was developed for the serological diagnosis of infections in mouse colonies. heat inactivated whole cell preparations of an isolate of p. pneumotropica biotype heyl (strain p 166) served as antigen for the elisa procedure and for immune serum production in germ-free han:nmri mice. cross reactions with the autochthonous flora of han:nmri spf-mice were not observed, but were evident when a p. pneumotropica ant ...19882966877
abnormality of an index of alveolar-capillary barrier permeability associated with respiratory tract infection in the rat.the study investigated the role of subclinical respiratory tract infection in producing an abnormality of lung function assessed by measuring an index of the permeability of the blood-gas barrier to 99mtcdtpa. pasteurella pneumotropica was grown from throat swabs taken from 9 female rats age 10 weeks at the time of the experiment and housed under conventional husbandry conditions for 4 weeks previously. there was a significant association between the amount of bacteriological growth and an abnor ...19836235398
enteritis caused by pasteurella pneumotropica infection in hamsters.pasteurella pneumotropica was isolated in essentially pure cultures from the bowels of hamsters with enteritis 7 days after parturition. newly received hamsters showed presence of p. pneumotropica in their nasal cavities but not in their uteri, lungs, spleens, or bowels.19854044801
[pasteurella pneumotropica infection in a barrier-maintained rat breeding colony]. 19806453481
secondary infection of rat lungs with pasteurella pneumotropica after kilham rat virus infection.lung congestion was observed after an outbreak of kilham rat virus infection (krv) in a rat colony, previously free of all rat viruses. a high proportion of congested lungs contained pasteurella pneumotropica suggesting that krv might have caused primary damage to the alveoli (hitherto not recorded) which allowed the secondary bacterial colonization. experimental infection of rats with krv caused acute damage to the lung alveoli. since krv infection is very common in animal facilities it could t ...19816457220
latent pasteurella pneumotropica infection of the gnotobiotic and barrier-held rats. 19734356333
pasteurella pneumotropica isolated from bone and joint infections.pasteurella pneumotropica is a normal inhabitant of the oropharynx of mice, rats, cats, and dogs. we describe here the first reported case of joint and bone involvement in a human. the need for culturing and adequate prophylactic treatment is discussed.19846470102
[pasteurella pneumotropica sepsis]. 19957731309
bacterial and mycoplasmal flora of the middle ear of laboratory rats with otitis media.purulent otitis media was confirmed at necropsy in 35 laboratory rats, 14 of which had shown clinical signs of middle ear infection. the bacterial flora of both the affected and grossly normal middle ears was similar, often mixed, and comprised mainly of staphylococcus haemolyticus, pasteurella pneumotropica and corynebacterium spp. twenty-one isolates of mycoplasma spp. were recovered from the middle ears of 11 rats with purulent otitis media and one normal rat. fourteen of the isolates were fu ...19846513509
synergistic effect in viral-bacterial infection: combined infection of the murine respiratory tract with sendai virus and pasteurella pneumotropica.synergism was demonstrated between sendai virus and pasteurella pneumotropica in the respiratory tract of mice showing no evidence of previous infection with either agent. mice aerosol challenged with p. pneumotropica invariably eliminated the viable organism from their lungs within 72 h. in contrast, intrapulmonary killing was delayed in animals previously infected with sendai virus. maximum synergism was observed when virus infection preceded bacterial challenge by 6 days. at this time, a mort ...19734356072
pathologic features associated with decreased longevity of mutant sphha/sphha mice with chronic hemolytic anemia: similarities to sequelae of sickle cell anemia in humans.a colony of sphha/sphha mice with congenital hemolytic anemia and an abnormality in erythrocyte spectrin assembly was screened to determine the cause of premature death. sphha/sphha mice have decreased life span, with 50% of animals dying by 6 months of age. the phenotype of these mutant mice includes moderate anemia (hematocrit: 21 to 28%), reticulocytosis, leukocytosis, lymphocytosis, extensive extramedullary hematopoiesis in spleen and liver, lymph node hyperplasia and membranoproliferative g ...19938355480
pasteurella pneumotropica and the prevalence of the ahp (actinobacillus, haemophilus, pasteurella)-group in laboratory animals.134 bacterial isolates originally identified as pasteurella pneumotropica were cultured from healthy, ill or dead mice, rats, hamsters, guinea pigs, rabbits and cats originating from 7 conventional laboratory animal facilities. they occurred seldom in pure culture and were found in a variety of organs. thorough identification (41 criteria) revealed that only 83 isolates (62%) were p. pneumotropica and could be subdivided into 3 biotypes. 3 isolates were p. aerogenes, 1 was p. ureae, 11 (8%) were ...19836345932
effect of pasteurella pneumotropica on the growth of transplanted walker sarcoma cells. 19806968573
isolation of pasteurella pneumotropica from rodents in south africa.four thousand, five hundred and sixteen rodents of 27 species were captured in widely separated localities in south africa over a period of ten years. samples of spleen, lung, heart, liver and rectal tissue with faeces were tested for the presence of zoonotic bacteria and 109 isolations of pasteurella pneumotropica were made from 11 species. latent infection with the organism was found to be widespread although there were temporal fluctuations in prevalence. field and laboratory evidence suggest ...19827097004
increased frequency of isolation of pasteurella and actinobacillus species and related organisms.ninety-six clinical isolates of pasteurella, actinobacillus and related organisms were submitted to our reference laboratory for identification. the procedures for detecting the 11 identified species, pasteurella multocida, pasteurella haemolytica, pasteurella ureae, pasteurella pneumotropica, actinobacillus lignieresii, actinobacillus equuli, actinobacillus actinomycetemcomitans, haemophilus aphrophilus, cardiobacterium hominis, and two unnamed species of cdc groups, hb-5 and ef-4, are describe ...19846468368
isolation of actinobacillus lignieresii and actinobacillus equuli from laboratory rodents.actinobacillus lignieresii and actinobacillus equuli were cultured from a total of 36 guinea pigs, rats, and mice. the organisms were isolated from the oropharynx, the conjunctiva, and middle ear. isolates were initially screened by eight biochemical tests to determine whether they were of the genus actinobacillus. actinobacillus spp. were then differentiated by fermentation reactions of nine carbohydrates. in the past, actinobacilli may have been mistakenly identified as pasteurella spp., espec ...19807217333
mutual viral and bacterial infections after housing rats of various breeders within an experimental unit.fifteen athymic rat strains from 11 breeding colonies were housed within an experimental facility for an immunological study. health status records supplied with 14 of the strains listed infections by kilham's rat virus (krv), clostridium piliforme (bacillus piliformis) and pasteurella pneumotropica for 2, 2 and 1 colonies respectively. in sera taken previous to the study from euthymic rats of 10 strains, antibodies to krv were detected in 3 strains, to pneumonia virus of mice (pvm), rat corona ...19968709572
mixed pleural space infection due to pasteurella pneumotropica and peptococcus magnus. 19846593950
experimental investigation of uterine infections of mice due to pasteurella pneumotropica. 19724675140
proliferation of pasteurella pneumotropica at oestrus in the vagina of rats.using a colony of wistar-imamichi rats contaminated with p. pneumotropica, the vaginal microflora was qualitatively and quantitatively investigated by swabbing. p. pneumotropica was the most dominant organism in the majority of rats examined. the population of p. pneumotropica and indigenous bacteria increased significantly higher at oestrus than in other oestrous stages. by the vaginal flushing technique changes in the population of p. pneumotropica and total bacteria, and changes in vaginal ce ...19836687195
[selective media for pasteurella pneumotropica].bacteria from the subcutaneous abscesses which appeared in a laboratory colony of ds mouse since october of 1977 were identified as pasteurella pneumotropica by various biological examinations. the abscess formation was limited to multiparous female mice over 100 day-age, but virgin females were free from the disease. the mic of various antibacterial substances showed that potassium tellurite, kanamycin and bacitracin were effective to isolate the organism selectively from various infection site ...19873678366
conjunctivitis in the nude rat (rnu/rnu).nude rats are susceptible to similar eye problems to those suffered by nude mice, notably conjunctivitis leading to periorbital abscesses. pasteurella pneumotropica has been isolated from the conjunctiva. the condition can be alleviated by washing the eyes of mildly affected rats with warm water. more severe cases respond to treatment with ampicillin. conjunctivitis has not appeared in a germ-free colony of nude rats.1979439841
[rearing of germfree rabbits and establishment of an spf rabbit colony].baby rabbits hysterectomy-derived from conventional japanese white rabbits were reared under aseptic condition by feeding with 4 types of artificial diets. rabbit milk for the artificial diet was obtained from conventional dams at 7--25 days after delivery. the artificial diets was given by stomach tube twice a day. the total volumes of diet given (ml per day) were y = 2.3x + a (1 to approximately 14 days of age), y = 32.2 + a (l5 to approximately 25 days of age), or y = (32.2 + a) - 37.5 (x - 2 ...1979155008
actinobacillus and pasteurella species isolated from horses with lower airway disease.seventy-three bacterial isolates from 65 horses with and without evidence of lower airway disease were identified to assess whether the association with disease was accounted for by a small or large number of species. just over half (50.5 per cent were actinobacillus equuli, 17.8 per cent were a suis-like, 11 per cent were pasteurella pneumotropica, 8.2 per cent were a lignieresii, 6.8 per cent were p haemolytica and 5.5 per cent were p mairii. these results suggest that a range of actinobacillu ...19989787421
abscesses of the bulbourethral glands of mice due to pasteurella pneumotropica. 19734747265
two actinobacillus species isolated from laboratory rodents.a study was made of the cultural and biochemical characteristics of 17 strains of actinobacillus isolated from laboratory rats and hamsters. 2 types were recognized which differed in their urease reaction and colony colour on blood agar. the results obtained suggest that one was actinobacillus equuli but the other could not be identified as belonging to a described species. the characteristics of both organisms are such that they could be confused with pasteurella pneumotropica. one of the types ...19807188999
[pasteurella pneumotropica isolated from the conjunctival mucosa of healthy laboratory mice]. 19744446854
bacterial phylogenetic clusters revealed by genome structure.current bacterial taxonomy is mostly based on phenotypic criteria, which may yield misleading interpretations in classification and identification. as a result, bacteria not closely related may be grouped together as a genus or species. for pathogenic bacteria, incorrect classification or misidentification could be disastrous. there is therefore an urgent need for appropriate methodologies to classify bacteria according to phylogeny and corresponding new approaches that permit their rapid and ac ...199910542177
non-dinitrophenyl-binding immunoglobulin that bears a dominant idiotype (id460) associated with antidinitrophenyl antibody is specific for an antigen on pasteurella pneumotropica.we have previously described an idiotype (id460) that transiently dominates anti-2,4-dinitrophenyl (dnp) antibody responses of mice that possess the appropriate igh-v and v kappa genotypes. normal serum has significant levels of id460 that does not bind dnp, and hybridomas derived from spleen cell fusions that produce monoclonal antibodies with these characteristics have been generated. many of these monoclonal, id460-positive antibodies bind the opportunistic mouse pathogen pasteurella pneumotr ...19846198421
protection against pasteurella pneumotropica during infection with angiostrongylus cantonensis.lung infections of specific-pathogen-free rats were studied to determine cross-immunity between infections with pasteurella pneumotropica and angiostrongylus cantonensis. rats were found to have differences in mortality due to pneumonic infections with p pneumotropica and a cantonensis and to coinfections of p pneumotropica and a cantonensis. single infections of p pneumotropica were not dosage-dependent in their lethality for specific-pathogen-free rats. the mortality of coinfection with p pneu ...19836226222
antibiotic resistance in bacterial isolates from laboratory animal colonies naive to antibiotic treatment.antiobiogrammes were made of a number of isolates of staphylococcus aureus, escherichia coli and pasteurella pneumotropica derived from rodent, rabbit or minipig colonies never treated with antibiotics. for s. aureus no differences between rats and mice were found in the percentage of resistant isolates. gentamicin and erythromycin were found to be the most efficient, while the highest percentages of resistance were found to be against penicillins and sulphonamides. in general, the results from ...200011072863
pasteurella pneumotropica infection resulting from a cat bite. 19695814192
an enzyme-linked immunosorbent assay (elisa) for monitoring rodent colonies for pasteurella pneumotropica enzyme-linked immunosorbent assay (elisa) was developed for the detection of pasteurella pneumotropica antibodies in the sera of rats, mice, hamsters and mastomys. p. pneumotropica from mice and rats showed cross-reactivity. the elisa using p. pneumotropica nctc 8284 detected more infected animals than selective culture in groups of rodents from which p. pneumotropica, haemophilus sp and/or actinobacillus sp were cultured. cross reactivity between p. pneumotropica nctc 8284 and haemophilus an ...19957564216
reclassification of 30 pasteurellaceae strains isolated from rodents.thirty pasteurellaceae strains isolated from gerbil, guineapig, hamster, mouse, muskrat and rat were reinvestigated and reclassified after comparison with reference strains. strains originally described as pasteurella pneumotropica were reclassified as [pasteurella] pneumotropica heyl biotype (7), [p.] pneumotropica jawetz biotype (1), pasteurella dagmatis (1) or taxon 22 (2). strains previously reported as actinobacillus sp. were reclassified as [p.] pneumotropica biotype jawetz (3), p. dagmati ...19957564217
antibiotic treatment of nude rats and its impact on the aerobic bacterial flora.a colony of nude rats were treated with the antibiotics ampicillin, spiramycin, sulfadoxine/trimethoprim, tetracycline, lincomycin and spectinomycin over a period of 30 weeks. the rats were monitored bacteriologically during the whole treatment period and for a period of 24 weeks after the treatment. antibiograms of each isolated microorganism were made in vitro. the primary target, pasteurella pneumotropica, was suppressed by the treatment, but reappeared after ending the medication. klebsiella ...19957707676
an enzyme-linked immunosorbent assay (elisa) for monitoring antibodies to sp group pasteurellaceae in guineapigs.cross-reactivity studies with pasteurellaceae from guineapigs revealed 5 serologically distinct groups, comprising pasteurella multocida, sp group bacteria, sp-like bacteria, pasteurella pneumotropica and an actinobacillus-like bacterium. guineapig pasteurellaceae differed serologically from mouse-derived p. pneumotropica nctc 8284. an enzyme-linked immunosorbent assay (elisa) using sp group antigen, developed to monitor 'natural' infections by sp group pasteurellaceae in guineapigs, detected si ...19957707680
septicemia due to pasteurella pneumotropica: 16s rrna sequencing for diagnosis confirmation.bacteremia due to pasteurella pneumotropica occurs infrequently. we report a case of septicemia in a 72-year-old woman who had no underlying illness. the microorganism was isolated from 10 blood cultures and identified by conventional and molecular methods. this is the first reported case of p. pneumotropica septicemia in an immunocompetent patient. the history of p. pneumotropica diseases in animals and humans and their varied clinical features are reviewed.200211825998
bacteremia in children: etiologic agents, focal sites, and risk factors.a prospective study was carried out on 210 cases of children under 10 years of age with fever. cases of gastroenteritis, respiratory tract infections, and suspected sepsis in children seen or admitted to the pediatric hospital were studied. clinical and microbiological data were recorded in a questionnaire or obtained from patient medical records. most of the children with septicemia (71.3 per cent) were less than 1 year old. focal source of bacteremia was gastroenteritis (40.4 per cent), pneumo ...200111827304
prevalence of a novel capsule-associated lipoprotein among pasteurellaceae pathogenic in animals.capsular serotype a strains of pasteurella multocida of avian origin express a 40-kda lipoprotein (plp-40) thought to attach the extracellular polysaccharide to the cell surface. the objective of the present study was to assess the prevalence of plp-40 in p. multocida strains of disparate serotypes and host origins, as well as other pathogenic members of the family pasteurellaceae. exponential-phase reference and clinical isolates were radiolabeled with [3h]-palmitate, lysed to obtain whole-cell ...200211910502
[pasteurella pneumotropica skin infection in a child]. 19947831223
colonization pattern of pasteurella pneumotropica in mice with latent pasteurellosis.colonization pattern of pasteurella pneumotropica (p. pneumotropica) in mice with latent pasteurellosis was examined with the original selective media, nkbt medium and tgn broth. in the mice of 0 to 15 weeks old, the organism was mainly isolated from the upper respiratory tract, lower intestinal tract, feces and vagina, with the highest isolation rate in the pharyngolarynx. in the pregnant and lactating mice, the organism was isolated from the same sites, but not from the uterus, fetus or mammar ...19947925625
prevalence and biochemical properties of v factor-dependent pasteurellaceae from rodents.organs of 1436 rats and 2839 mice were monitored for v-factor dependent pasteurellaceae. such bacteria were isolated from 21.2% of rats and from 2.4% of mice, respectively. they were most frequently cultured from the deep respiratory tract (lungs and trachea). in addition, they were found in the nasal cavity and on mucous membranes of the genital and the intestinal tract. 35 phenotypical criteria were determined for 429 isolates. based on these data, groups of bacteria showing similar biochemica ...19938369581
pasteurella pneumotropica pneumonia in a patient with aids. 19958562763
pasteurella pneumotropica abscess syndrome in a mouse colony. 19695388183
pneumocystis carinii infection in transgenic b cell-deficient mice.pneumocystis carinii is an important cause of pneumonia in immunocompromised hosts. both cellular and humoral immunity seem important in resistance to this pathogen, but the specific role of each component is poorly understood. an outbreak of p. carinii pneumonia in transgenic b cell-deficient mice (mumt) was studied. over 4 months, >50% of 41 mumt/mumt mice maintained in a sterile environment died of pneumonia. some mice had concurrent infection with pasteurella pneumotropica. homozygous mumt/m ...19968603947
rederivation of mice by means of in vitro fertilization and embryo vitro fertilization and embryo transfer were performed for rederivation of four strains of mice harbouring mouse hepatitis virus (mhv) and/or pasteurella pneumotropica (p. pneumotropica). superovulated oocytes were fertilized by preincubated cauda epididymis sperm in vitro. fertilized eggs at 2-cell stage were transferred into the oviducts of specific pathogen free (spf) recipients. microbial examination of sperm and/or oocyte donors verified the presence of p. pneumotropica and/or of antibod ...19968689578
detection of pasteurella pneumotropica in laboratory mice and rats by polymerase chain reaction.a 16s rdna-based polymerase chain reaction (pcr) method specific for pasteurella pneumotropica was developed. the pcr product, a 395-base pair dna fragment, was amplified from p. pneumotropica and not from 42 other bacterial species tested, including four other pasteurella species and actinobacillus ureae. the pcr method was used to identify 13 previously isolated strains that had been identified as p. pneumotropica by conventional methods: 12 were confirmed by pcr; one that was pcr-negative was ...19968699827
efficacy of various therapeutic regimens in eliminating pasteurella pneumotropica from the mouse.pasteurella pneumotropica, a gram-negative opportunistic pathogen, can be isolated from the oropharynx, intestinal tract, and reproductive tract of clinically normal mice and has been associated with various clinical syndromes, including conjunctivitis, infections of the reproductive tract, otitis, and subcutaneous abscess formation. enrofloxacin, a fluoroquinolone bactericidal antimicrobial, has been shown to be effective in eliminating p. multocida from rabbits. we sought to determine whether ...19968799933
isolation of pasteurella ureae from reproductive tracts of congenic mice.infertility noted in two congenic strains of mice was associated with abortion, metritis, and stillbirths. pasteurella pneumotropica was recovered from affected uterine tracts of atl mice. tetracycline treatment for 6 weeks was instituted in an attempt to minimize pasteurella-associated infertility. nine atl mice and 12 ath mice were examined 4 and 12 months after cessation of tetracycline therapy, respectively. histopathologically, all animals appeared normal. p. pneumotropica was recovered fro ...19817251825
myopathy and spontaneous pasteurella pneumotropica-induced abscess formation in an hiv-1 transgenic mouse an effort to augment human immunodeficiency virus type 1 (hiv-1) gene expression in transgenic mice, an infectious proviral dna clone was modified by deleting the two nf kappa b binding sites and some adjacent upstream ltr sequences and replacing them with the core enhancer of moloney murine leukemia virus (mlv). two independent lines of mlv/hiv transgenic mice were established that expressed hiv-1-specific rna in lymphoid tissue, striated skeletal muscle, and the eye lens. heterozygous anima ...19968862275
randomly amplified polymorphic dna polymerase chain reaction assay for molecular epidemiologic investigation of pasteurella pneumotropica in laboratory rodent colonies.after an episode of clinical pasteurella pneumotropica infection was diagnosed in a c57bl/6n mouse, a randomly amplified polymorphic dna polymerase chain reaction assay (rapd-pcr) was developed and used to genetically characterize and differentiate 52 field isolates and laboratory reference strains of p. pneumotropica and related bacteria. a survey of rodents in the facility recovered 36 isolates of p. pneumotropica from 30 mice, six isolates from hamsters, and three isolates from rats during th ...19968872988
evaluation of pcr as a means of identification of pasteurella pneumotropica.a polymerase chain reaction with new primers (new pcr) designed from pasteurella pneumotropica 16s rdna as an identification system for this organism was compared with the pcr reported by wang et al. (wang's pcr) by using 15 bacterial reference species and 70 clinical isolates with the conventional identification system. for the 15 reference strains, both pcrs were identical. for the 70 clinical isolates, the new pcr and wang's pcr showed consistency with the conventional system in 62.9% (44/70) ...199910067207
pasteurella pneumotropica as a causal microorganism of multiple subcutaneous abscesses in a colony wistar rats. 19705508979
identification by 16s rdna fragment amplification and determination of genetic diversity by random amplified polymorphic dna analysis of pasteurella pneumotropica isolated from laboratory rodents.pasteurella pneumotropica is an opportunistic bacterium frequently isolated from colonies of various laboratory rodents. identification of this species, including its differentiation into two distinct biotypes (jawetz and heyl), is usually based on the use of conventional bacteriologic methods. in this study, a 16s rdna fragment amplification procedure was developed for use as an alternative method for identification and differentiation of p. pneumotropica. polymerase chain reaction (pcr) produc ...199910090094
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