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induction of the acetamidase of aspergillus nidulans by acetate metabolism.growth tests and enzyme determinations strongly suggest that the acetamidase of aspergillus nidulans is induced by a product of acetate metabolism rather than the substrate, acetamide. the cis-dominant mutation, amdi9, which is closely linked to amds, the structural gene for the acetamidase, results in greatly increased sensitivity to induction by acetate metabolism. propionate, l-threonine, and ethanol also result in acetamidase induction. mutations in the faca, facb, and facc genes, which lead ...197719418
dipeptidylaminopeptidase and carboxypeptidase activities of the brush border of rabbit small intestine. 197830675
haemophilus somnus complex: antigenicity and specificity of fractions of haemophilus somnus.five haemophilus somnus type 8025 preparations (whole cell, sonicate, crude polysaccharide, purified polysaccharide, and protein) were produced for studies of their antigenicity in rabbits. bacterial agglutination and passive hemagglutination tests were used to assess the level of antibody produced in rabbits inoculated with the different antigenic preparations. cross-reactions were seen between the antiserums against the h sumnus 8025 antigens and a variety of related and unrelated bovine patho ...197550755
alteration of human blood cells and changes in plasma mediators produced by radiographic contrast media.in vitro incubation of human blood cells with iodinated radiographic contrast media (rcm) produced marked effects which were dose-dependent: erythrocytes showed crenation which was reversible; neutrophil leukocytes released the lysosomal enzyme beta-glucuronidase; basophil leukocytes released histamine; and platelets released serotonin as well as beta-glucuronidase. the release reaction could not be attributed to cell lysis, as demonstrated by the release of the cytoplasmic enzyme lactic dehydro ...197985375
tumor-associated antigens in cervical cancer tissues and in sera from patients with cervical cancer or with head and neck cancer.hyperimmune new zealand white rabbit sera prepared against partially purified tumor-associated antigens (taa) of invasive cervical cancer tissues (cacx's) were used to demonstrate taa in cacx's and circulating taa (c-taa) in sera from patients with cervical cancer or with head and neck cancer. anti-cacx serum adsorbed with pooled normal cervical tissue (ncx) antigen preparations and with lyophilized pooled normal human plasma gave precipitin in gel reactions with cacx but not with ncx, which ind ...197988537
observations on fast axoplasmic transport in peripheral nerve following repetitive electrical stimulation.in a series of 13 cats the effect of electrical stimulation of peripheral nerve on the mechanism of fast axoplasmic transport was studied. electrical stimulation was used for varying time periods at parameters reported in the range of those used to produce electroanalgesia in man. our results indicate that at these parameters, electrical stimulation produced no effect on this important aspect of nerve function, and, therefore, our work lends support to the safety of these devices in pain states.197993738
actinobacillus seminis infection in sheep in the republic of south africa. iii. growth and cultural characteristics of a. seminis.bacteriological tests were done on a large number of different strains of actinobacillus seminis and also, repeatedly, on the same culture or on different cultures taken periodically from the same donor animal. these tests were also applied to strains of a. seminis representing different serological types, which in turn were compared with strains of brucella ovis. the tests as applied proved that a. seminis strains have defined, morphological, staining, cultural and biochemical properties, altho ...197995214
the effect of nalidixic acid, rifampicin and chloramphenicol on the synthesis of phospholipase c in bacillus cereus.the effect of nalidixic acid, rifampicin and chloramphenicol on the synthesis of phospholipase c (ec 3.1.4.3) has been studied in washed bacillus cereus cells resuspended in nutrient broth. in the absence of inhibitors, the synthesis showed a biphasic pattern. no synthesis of release of enzyme was found in the presence of chloramphenicol. when rifampicin was added, phospholipase c synthesis continued for 10-15 min. nalidixic acid, at concentrations which inhibited dna synthesis completely, permi ...197896661
metabolism studies with practolol [proceedings]. 197896899
pre-immunization and post-exposure treatment with inactivated rabies vaccine of chick embryo cell culture origin (cec).routine laboratory assay revealed that the potency of concentrated rabies vaccine of chick embryo cell culture (cec) origin was in the same level compared with suckling mouse brain (smb) vaccine. over one hundred persons received two doses of cec vaccine at an interval of one week and produced high level of neutralizing antibody against rabies virus. the monkeys experimentally infected with street rabies virus were satisfactorily protected by subcutaneous inoculation with cec vaccine one hour af ...197898373
catecholamine-induced alterations in glucose homeostasis in baboons, dogs, rabbits, and rats: comparative effects of somatostatin. 197898685
effect of intravenous sodium nitroprusside on cerebral blood flow and intracranial pressure.local cerebral blood flow was measured with the hydrogen clearance technique during intravenous infusion of nitroprusside in monkeys. concentrations of the drug required to reduce the mean arterial blood pressure by less than 40% resulted in no significant change or only a slight increase in regional cerebral blood flow. larger doses, however, produced a loss of cerebral autoregulation, thereby inducing a drop in cerebral blood flow. intracranial pressure rose proportionately to the nitroprussid ...197898731
pressure-dependent changes in nuclei and the process origins of the endothelial cells lining schlemm's canal.monkeys eyes were fixed with glutaraldehyde in vivo at positive intraocular pressure of 35 or 25 mm hg and compared with eyes fixed without a positive pressure gradient, with the use of light microscopy and transmission and scanning electron microscopy. the entire endothelial lining of the inner wall of schlemm's canal ballooned or distended toward the external wall of the canal at positive intraocular pressure. characteristic nuclear shapes were identified and appeared to result from the increa ...1979103860
tumor-host responses to various nutritional feeding procedures in rats.parenteral and enteral nutrition are being used as adjuncts to cancer therapy. a liquid diet formulation containing a 27% solution of glucose and 3.9% crystalline amino acids with electrolytes and vitamins was given continuously for a week via parenteral (iv), and via intragastric (ig) routes and also was given ad libitum via the oral or per os (po) route to groups of buffalo rats with and without a morris no. 7777 transplantable hepatoma to find out how these feeding procedures affect tumor-hos ...1979107299
purification and some physicochemical properties of staphylococcal enterotoxin d.a method was developed for the isolation of staphylococcal enterotoxin d in highly purified form from cultures of staphylococcus aureus strain 1151m. the method involves removal of the toxin from the culture supernatant fluid with the ion-exchange resin cg-50 followed by chromatography on carboxymethylcellulose (twice) and by gel filtration on sephadex g-75 (twice). the purified toxin is homogeneous by polyacrylamide gel and sodium dodecyl sulfate-polyacrylamide gel electrophoresis and double ge ...1979107962
bacterial ribosomes with two ambiguity mutations: effects of translational fidelity, on the response to aminoglycosides and on the rate of protein synthesis.a set of mutants affected in translational fidelity was constructed by transduction within an otherwise isogenic escherichia coli b argf40 argr11 background. alterations in ribosomal proteins s4, s5, s12 and l6 either as single mutations or in various combinations were compared for their effects on aminoglycoside phenotypes, on in vivo and in vitro misreading and on the rate of peptide bond formation. results may be summarized as follows: (i) strains carrying two ambiguity mutations on the ribos ...1979108518
evidence of central cholinergic mechanisms in the appearance of affective aggressive behaviour: dissociation of aggression from autonomic and motor phenomena.carbachol, muscarine, eserine and neostigmine injected into the cerebral ventricles of conscious cats evoked emotional behaviour with aggression, autonomic and motor phenomena as well as clonic-tonic convulsions. the main and the most impressive feature of the gross behavioural effects of intraventricular carbachol, muscarine, eserine and neostigmine in conscious cats was the affective type of aggression. however, neostigmine produced aggressive behaviour only in about one-quarter of the experim ...1979111280
similarities in the physiological bases of an abnormal grooming behavior in thyroidectomized cats and in cats with lesions of the central nervous system.thyroidectomized cats display a dissociation of the appetitive and consummatory components of grooming behavior when the body surface is tactually stimulated, an abnormal behavior that also occurs in cats with pontile or frontal neocortical lesions. systemic administration of 5-hydroxytryptophan (5-htp) abolishes the abnormal behavior, whereas dihydroxyphenylalanine administration does not, and p-chlorophenylalanine (pcpa) administration induces the abnormal grooming behavior in thyroidectomized ...1976135004
[cardiac arrhythmia in the rabbit under the effect of adrenaline and difluorodichloromethane (fc12)].inhalation of gas mixtures containing different concentrations of fc12 by anesthetized and normally oxygenated rabbits produces blood levels of fc12 which are stable and proportional to the rate of fc12 in the mixture. from the arterial concentration of 80 microgram/ml fc12 (10 % fc12) mixture) and over, fc12 alone causes effects proportional to doses: arterial pressure decrease with tachycardia; slight morphological alterations of the electrocardiogram at high concentration. arrhythmia never oc ...1977145298
the effects of hypokinesia on some organs of the digestive tract (submaxillary glands, stomach, small intestine and pancreas). 1978148052
the fourth volhard lecture: cardiovascular structural adaptation; its role in the initiation and maintenance of primary hypertension. 1978153216
identification and interrelationships of the variola/vaccinia subgroup of poxviruses. 1975164050
protein and glycoprotein electrophoretic patterns of enriched fractions of primary and secondary granules from guinea pig polymorphonuclear leukocytes.the postnuclear supernatant fraction of sucrose homogenates of guinea pig polymorphonuclear leukocytes (pmnl) was subjected to differential centrifugation to obtain a total particulate fraction, a particle-free supernatant fraction, highly enriched fractions of primary and secondary granules, and a membrane-rich fraction. the various fractions were solubilized in buffer containing sodium dodecyl sulfate (sds) and analyzed for protein and glycoproteincomponents by sds -polyacrylamide gel electrop ...1975166079
functional consequences of modifying highly reactive arginyl residues of fructose 1,6-bisphosphatase. loss of monovalent cation activation.modification of pig kidney fructose 1,6-bisphosphatase with 2,3-butanedione (in the presence of amp) results in the loss of activation of the enzyme by monovalent cations. under these conditions about 8 arginyl residues per mole of enzyme were modified. no other residues were modified. no loss of monovalent cation activation occurs when modification with 2,3-butanedione is carried out in the presence of amp plus the substrate fructose 1,6-bisphosphate and 3.2 less arginyl residues were modified. ...1975169892
[proceedings: differentiation of nephroblastoma]. 1975175610
mechanism of premature polypetide termination in a mouse ascites cell-free system programmed by encephalomyocarditis viral rna.the premature termination and release of encephalomyocarditis viral rna-programmed polypeptides were analyzed in a cell-free system from mouse ascites tumor cells. the kcl concentration affects the size distribution of products but not the extent of polypeptide release. the same major products (60,000 to 140,000 molecular weight) are found in both the soluble and particulate fractions. the majority of released polypeptides are free protein, whereas the ribosome-bound product is mostly in the for ...1976178909
steroid production by quartered and capsular rat adrenal gland in response to haemorrhage.60 min after rapid bleeding (1.5--2.0 per cent of b. w.) both aldosterone and corticosterone production rate by quartered rat adrenals were found to be elevated. however, no difference was observed in the rate of aldosterone and corticosterone production by capsular adrenals of sham operated and hypovolaemic rats. corticosterone production rate by decapsulated adrenals was much more higher after haemorrhage than in the control group. the same alterations could be observed incubating adrenal tiss ...1975179800
endonucleolytic cleavage of murine leukemia virus 35s rna by microsome-associated nuclease. 1976180996
preliminary observations of bovine adrenal fasciculata-reticularis cells in monolayer culture: steroidogenesis, effect of acth and cyclic amp.bovine adrenocortical cells dispersed by trypsin digestion of fasciculata-reticularis minces were maintained in monolayer culture for up to 6 weeks. during the first week cells grown in medium containing acth (1 mu/ml) secreted steroids at a rate 10 to 20-fold greater than control cultures, cortisol accounting for 80-90% of the corticotrophic response. using tracer amounts of [3h] progesterone and [3h] pregneolone, the major products were cortisol, corticosterone, 11-deoxycortisol and 11-deoxyco ...1976184635
specific release of plasma membrane enzymes by a phosphatidylinositol-specific phospholipase c.the release of plasma membrane ecto-enzymes by a phosphatidylinositol-specific phospholipase c from staphylococcus aureus was investigated. there was no effect on l-leucyl-beta-naphthylamidase, alkaline phosphodeisterase i and ca2+- or mg2+-atpase, but substantial proportions of the alkaline phosphatase and 5-nucleotidase were released. there was no simultaneous release of phospholipid and the solubilized enzymes were not exluded from sepharose 6-b. it was therefore concluded that release was no ...1978205248
analysis of cytoplasmic rna and polyribosmomes from feline leukemia virus-infected cells.cytoplasmic virus-specific rna and polyribosomes from a chronically infected feline thymus tumor cell line, f-422, were analyzed by using in vitro-synthesized feline leukemia virus (rickard strain) (r-felv) complementary dna (cdna) probe. by hybridization kinetics analysis, cytoplasmic, polyribosomat, and nuclear rnas were found to be 2.1, 2.6, and 0.7% virus specific, respectively. size classes within subcellular fractions were determined by sucrose gradient centrifugation in the presence of di ...1978205670
morphological revertants of an avian sarcoma virus-transformed mammalian cell line exhibit tumorigenicity and contain pp60src.the biological and biochemical properties of rous sarcoma virus-transformed and revertant field vole cells were investigated. revertant vole cells appear morphologically similar to normal, uninfected cells, yet, like transformed vole cells, they are fully capable of growing in agar suspension and producing tumors in athymic nude mice. these highly tumorigenic, yet morphologically normal appearing, vole cells express viral-specific antigens such as the gag gene product (pr76) but lack the env gen ...1979226988
cholinergic activity regulates muscarinic receptors in central nervous system cultures.muscarinic acetylcholine receptor activation induces a loss of muscarinic receptors from cultured neuroblastoma and embryonic chicken cerebrum cells. as measured by specific binding of [3h]quinuclidinyl benzilate, steady-state receptor concentrations decrease 75% in response to receptor-saturating concentrations of cholinomimetic drugs. both the degree and duration of activation determine the extent of receptor loss. a method for analyzing receptor turnover, which does not rely upon protein synt ...1979226997
field evaluation of haemophilus somnus bacterin. 1977242889
[studies on the pharmacology and chemistry of traditional chinese and folk medicinal plants (author's transl)]. 1979262811
salmonella serotypes, salmonella typhi phage types, and anti-microbial resistance at the university hospital of the west indies, jamaica.bacteriologically proved cases of salmonellosis presenting at the university hospital have increased nearly threefold since 1957. the most striking change has been a considerable increase in the incidence of salmonella heidelberg and salmonella derby in the last 5 years, probably resulting from hospital acquired infection. about 80 cases of typhoid fever are reported each year in jamaica. there has been little change in the prevalence of different phage types of salmonella typhi since 1961. para ...1977267669
[physiology, key to ergonomics]. 1977272687
tissue formation in the root canal after total pulpectomy and partial root filling.in twenty human teeth, total removal of the pulp was attempted, and the root canal was filled 2 to 4 mm. short of the foramen in the same sitting. the root filling consisted of gutta-percha points and kloroperka n-ö as a sealer. the teeth were extracted after observation periods of 2, 6, and 10 months and committed to histologic examination. microscopic evaluation demonstrated that after 2 months, the space in the canal between the root filling and the foramen was occupied by connective tissue s ...1978280836
developmental changes in the electrophoretic mobility of mouse splenic lymphoid cells. 1977302691
inherited immunodeficiency in chickens: a model for common variable hypogammaglobulinemia in man? 1977303448
cellular characteristics of the eosinophil compatible with a dual role in host defense in parasitic infections. 1977339759
l-methionine as an ethylene precursor in saccharomyces cerevisiae.l-methionine induced production of ethylene by saccharomyces cerevisiae growing in lactate medium. the production induced by l-methionine was inhibited by pyruvate, and elevated by glucose. labeled ethylene was produced when l-[u-14c]methionine, but not [u-14c]glucose, was fed to the yeast. the mutant s. cerevisiae g1332 (ade-, met-) did not produce significant amounts of ethylene unless l-methionine was added. thus l-methionine acts as a precursor of ethylene in s. cerevisiae. the role of gluco ...1977340018
[experiences with fenbendazole in the control of syphacia muris in the breeding of rats 2]. 1977340191
determination of thymidine in serum used for cell culture media.thymidine concentrations in serum used for cell culture media were determined with an assay based on isotope dilution. in this assay, incorporation of (3h)-thymidine into dna of cultured cells was measured in the presence of 5 and 20% serum as a function of the concentration of unlabeled thymidine added to the medium. in three batches of horse serum, thymidine concentrations were 0--0.17 micron, while in fetal calf serum values of 0.75--2.1 micron were obtained. dialysis of serum resulted in a ...1978340297
isolation of ureaplasma from bovine granular vulvitis.cultures for mycoplasmatales, viruses and bacteria were made from bovine vulvar swabs to determine whether ureaplasma was associated with a clinical granular vulvitis observed in 16 ontario dairy herds. ureaplasma was isolated from 23.5% of 34 clinically normal cows, 74% of 27 cows with mild to moderate vulvar hyperemia but no discharge and 100% of 20 cows with acute vulvar hyperemia accompanied by purulent discharge. there were statistically significant differences in rates of isolation among c ...1978352491
[meningitis caused by gram-negative bacteria: comments apropos of 14 cases]. 1978358330
marine cardioactive agents. adenosine and 2'-deoxyadenosine from dasychalina cyathina. 1978362107
the bovine haemophilus somnus complex: a clinical review. 1978364814
[laboratory experiments with a polyvalent extract vaccine for oral immunization against e. coli enteritis].bacteria of e. coli causing enteritis can be extracted by edta-sodium. these extracts having lower dry weights result in better protective effects in contrast to sodium-deoxycholate extracts. the edta-sodium extracts can be concentrated, purified and sterile filtrated. thus the production of polyvalent vaccines is possible. a direct relation exists between the effectiveness of the extracts and the virulence of the strains used for extraction. the more virulent the original strain the better is t ...1978373349
endotoxin-induced histamine hypersensitivity in mice. . . a model system for byssinosis? 1979384778
contribution of adrenal medulla, spleen and lymph, to the plasma levels of dopamine beta-hydroxylase and catecholamines induced by hemorrhagic hypotension in dogs. 1979438992
studies on conformational changes in f-actin of glycerinated muscle fibers during relaxation by means of polarized ultraviolet fluorescence microscopy.by means of polarized ultraviolet fluorescence microscopy the conformational changes of f-actin occuring in glycerinated muscle fibers of rabbit and barnacle (balanus rostratus hock.) under the influence of adenosine triphosphate in the presence of ethylene glycol bis(beta-amino-ethyl ether)-n,n'-tetraacetic acid were discovered. these changes seem to be located near the surface of the globules thus hampering the penetration of univalent iones and neutral molecules into the f-actin macromolecule ...1979470613
the experimental infection of calves with a british strain of haemophilus somnus.intravenous inoculation of a british strain of haemophilus somnus resulted either in fatal peracute or chronic forms of h somnus disease. pleuritis, pericarditis and arthritis were prominent post mortem findings. intratracheal inoculation led to severe cellulitis and abscess formation in the neck with acute suppurative bronchopneumonia in one calf, while in another, encapsulated abscesses and pleural adhesions were seen. intraperitoneal inoculation resulted in fatal fibrinous peritonitis in one ...1979472490
thromboembolic meningoencephalitis associated with haemophilus somnus infection. 1979505901
the activity of levamisole against benzimidazole resistant haemonchus contortus and trichostrongylus colubriformis. 1979516343
[acetylcysteine treatment of acute poisoning with epichlorohydrin and its synthesis semiproducts]. 1979516621
the effect of stimulation by meat on gastrins in pyloric antral mucosa of anaesthetized cats.chloralose anaesthetized cats were prepared with fundic and antral pouches. after stimulation with meat extract suspension in the antral pouches, the antral mucosae were collected, homogenized and subjected to subcellular fractionation to produce whole homogenates, debris, mitochondrial, granule and microsomal fractions and the cell supernatant. total gastrin concentration and the quantities of gastrin components were measured in these cell fractions and compared with values obtained from a grou ...1979521924
bone changes in alcoholics.man has consumed alcohol for its euphoric and sedative effect down through the ages. attention in the medical literature has been primarily focused on the effects of alcohol on the nervous system and liver. in the past few years, isolated reports have appeared in the medical literature concerning the effects of alcohol on the bony skeleton. the purpose of this paper is to classify these lesions, discuss their pathophysiology, and briefly review their clinical course. the lesions discussed includ ...1979522187
can glucose transport across the human erythrocyte membrane be sustained against a concentration gradient? [proceedings]. 1979529066
effect of oxytocin on renal sodium and chloride excretion in long evans and brattleboro rats [proceedings]. 1979529155
suppression of potassium-recycling in the renal medulla by short-term potassium deprivation.recently we proposed that potassium, like urea, normally undergoes medullary recycling from collecting tubule to the pars recta or descending limb of the juxtamedullary nephron and suggested that the extent of recycling is a function of the concentration of potassium in collecting tubule fluid. to test this hypothesis further, we fed young rats a potassium-free diet for 3 days and then prepared them for micropuncture of the left renal papilla. compared to findings in normally fed animals, potass ...1979548609
septicemia and meningoencephalitis in pastured cattle caused by a haemophilus-like organism ("haemophilus somnus").septicemia and meningoencephalitis developed in 10 pastured cattle 7 months to 3 years of age. two unrelated herds were involved. necropsy findings were similar to those previously reported in cattle infected with a haemophilus-like organism, including multifocal intramuscular hemorrhages, suppurative polyarthritis, and multifocal hemorrhagic thrombi in the brain. a haemophilus-like organism was isolated from one animal. it was characterized by growth on blood agar or tryptose agar plus a feeder ...1977558084
pathology of experimental histophilus ovis infection in sheep. ii. pregnant ewes.intravenous inoculation of histophilus ovis to pregnant ewes at mid or late gestation resulted in acute bacterial endometritis, placentitis and foetal death. there were no lesions in the foetuses but h. ovis was recovered from the uteri of the ewes and the placentas. oral or intravaginal administration had no effect.1978571643
correlation of microbiological and histological findings in bovine fibrinous pneumonia.in a retrospective morphological and microbiological study, 39 of 55 cases of bovine fibrinous pneumonia were diagnosed as fibrinous pleuropneumonia. twenty-nine of these 39 (74%) were associated with pasteurella hemolytica, but only two cases (5%) with p. multocida. in contrast, of the 16 cases classified as fibrinous bronchopneumonia, one (6%) was associated with p. hemolytica, and nine (56%) with p. multocida. in eight cases mycoplasma and hemophilus somnus were found in association with eith ...1978685079
pathology of experimental histophilus ovis infection in sheep. i. lambs.inoculation of lambs either intravenously or intranasally with histophilus ovis resulted in septicaemia. there was bacterial thrombosis and vasculitis in the liver, lung, kidneys and heart. these lesions were similar to those in natural cases of the disease. with intravenous inoculation of a less virulent isolate there were abscesses in the subcutaneous tissues, muscle fascia and joint bursae.1978716158
immunogenicity of a haemophilus somnus bacterin in cattle. 1978736328
serological comparison between histophilus ovis, actinobacillus seminis and brucella ovis.the serological relationships between 4 strains of histophilus ovis, the neotype strain of actinobacillus seminis and brucella ovis were examined using a cross-absorption complement-fixation technique. it was found that the 4 strains of h. ovis were serologically homologous and that an incomplete relationship existed between these organisms and a. seminis. anteriserums prepared against one strain of h. ovis and the strain of a. seminis gave a weak, apparently non-specific cross-reaction with br. ...1978743054
[infectious septisemic-thrombosing meningoencephalitis in a feeder bull herd. iv. bacteriological studies: isolation of haemophilus-like bacteria strains (haemophilus somnus)]. 1976782821
the isolation of haemophilus somnus following sudden deaths in suckler calves in scotland.a blood or yeast dependent pleomorphic gram-negative bacillus was isolated from the pneumonic lung of a suckled calf which died suddenly. the organism was biochemically similar to american strains of haemophilus somnus and was shown to be serologically similar by rapid slide agglutination, tube agglutination and micro-complement fixation tests. the possible importance of this organism in disease syndromes in cattle in the united kingdom is discussed.1977847871
histophilus ovis infection in sheep in western victoria.organisms resembling histophilus ovis were isolated from sheep in western victoria in association with synovitis, septicaemia and/or abscessation in 2 to 8 week old lambs. histopathological lesions in these lambs were indicative of bacterial embolism with thrombosis. similar organisms were also isolated from sheep in 2 flocks with a high neonatal mortality rate. these isolations were from vaginal swabs from the ewes, placentas and from one lamb which had meningitis, ependymitis, choroid plexitis ...1977869799
septicemia and meningoencephalitis in pastured cattle caused by a haemophilus-like organism ("haemophilus somnus").septicemia and meningoencephalitis developed in 10 pastured cattle 7 months to 3 years of age. two unrelated herds were involved. necropsy findings were similar to those previously reported in cattle infected with a haemophilus-like organism, including multifocal hemorrhages in some muscles, suppurative polyarthritis, and multifocal hemorrhagic thrombi in the brain. a haemophilus-like organism was isolated from one animal. it was characterized by growth on blood agar or tryptose agar plus a feed ...1977872592
haemophilus somnus complex: in vitro interactions of haemophilus somnus, leukocytes, complement, and antiserums produced from vaccination of cattle with fractions of the organism. 1977879574
diagnostic procedures in experimental hemophilus somnus infection in cattle. 1977880540
phycomycosis associated with encephalitis caused by haemophilus somnus in a heifer.numerous fungal hyphae resembling those of a phycomycete were found in thrombi, vessel walls, and areas of inflammatory cell infiltration within a large focus of necrosis in the brainstem of a 2-year-old heifer. haemophilus somnus and pasteurella multocida were isolated from the same lesion. antemortem hyperglycemia was also demonstrated.1977903285
a comparison of various haemophilus somnus strains.sixty-eight haemophilus somnus strains isolated from the bovine in canada and the u.s.a. were compared. in media enriched with 5% ovine serum, 5% bovine serum and 10% yeast extract, h. somnus fermented glucose, levulose, maltose, mannitol, mannose, sorbitol, trehalose and xylose, but failed to ferment arabinose, dulcitol, galactose, inositol, lactose, raffinose, rhamnose, salicin and sucrose. the organisms acidified litmus milk, produced cytochrome oxidase, indole and hydrogen sulfide (h(2)s) an ...1977922555
colonization and transmission of haemophilus somnus in cattle. 1977931158
complement fixation titers in cattle following intranasal inoculation of hemophilus somnus.five bulls were inoculated intranasally with a live culture of hemophilus somnus originally isolated from a clinical case of hemophilus septicemia. preinoculation and postinoculation blood samples were taken at weekly intervals for nine weeks for measuring complement fixation titers and daily postinoculation temperatures were taken for one week. three animals had transient fever and slight lethargy was observed in two animals had a transitory rise in complement fixation titers in the second to f ...19761000404
blockade by morphine of acetylcholine release from the caudate nucleus in the mid-pontine pretrigeminal cat. 19751111819
bovine abortion associated with haemophilus somnus. 19751147347
[infection with the so-called "haemophilus somnus" in cattle: isolation and characterization of strains from respiratory organs and genitalia]. 19751162322
transport and storage of serotonin by thrombin-treated platelets.repeated thrombin treatment of washed platelets prepared from rabbits can decrease the serotonin content of the platelets by about 80%. when these platelets are deaggregated they reaccumulate serotonin but their storage capacity for serotonin is reduced by about 60%. if thrombin-pretreated platelets are allowed to equilibrate with a high concentration of serotonin (123 mu m), they release a smaller percentage of their total serotonin upon further thrombin treatment, in comparison with the percen ...19751168649
recommended classification of pesticides by hazard. 19751189405
abortion associated with hemophilus somnus infection in a bovine fetus. 19751212643
[morphological changes in the internal organs and endocrine glands of rats subjected to deficient nutrition and fasting].pathological studies on the internal organs, endocrine glands inclusive, are carried out in white rats under conditions of deficient alimentation and fasting. the results of the study show that complete starvation with preceding full value or restricted (2 hours daily) feeding brings about a variety of morphological reactions in the internal organs and endocrine glands. the liver proves to be the most sensitive to reduced food supply it shows a marked response with fatty dystrophy and subsequent ...19751235999
[changes in protein metabolism in white rats with limited feeding and a varying physical load].changes in some protein metabolism indicators are studied in white rats at different levels of the energy balance. it is established that the level of the so-called labile protein in the organism is closely related to the level of energy metabolism and also, that it is not invariably directly dependent on protein concentration within the organism. the inference is reached that adaptivity of protein metabolism is manifested not merely through changes in the value of proteins, which might be emplo ...19751236000
the incorporation of [1(-14)c] acetate into unesterified fatty acids in rat cerebral cortex in vivo. 19761255197
isomeric inversion of ibuprofen (r)-enantiomer in humans.enantiomeric compositions of the major urinary metabolites of ibuprofen [(rs)-2-(4-isobutylphenyl)propionic acid]were characterized after oral administration of the racemic mixture and oral administration of the individual enantiomers to normal human volunteers. resolution of the diastereomeric amides, formed by reaction of the urinary metabolites with (s)-(-)-alpha-methylbenzylamine, was achieved by glc. only the (r)-(-)-enantiomer of the intact drug was inverted to its optical antipode, (s)-(+ ...19761255461
proceedings: uptake and incorporation of (u-14c)glucose during culture of mouse blastocysts previously undergoing normal implantation and induced delay of implantation. 19761255628
aminobenzioc acid diuretics. 8.(2) 3, 4-disubstituted 5-methylsulfonylbenzioc acids and related compounds.various 2, 4- and 3, 4-disubstituted 5-methylsulfonylbenzoic acids were synthesized as methylsulfonyl analogues of previously described 5-sulfamoylbenzoic acid diuretics. the results of the diuretic screening in dogs reveal that substitution of the sulfamoyl group by the spatially and sterically similar methylsulfonyl group does not affect the diuretic pattern but leads generally to somewhat decreased potency. for the highly potent 3-benzylamino-4-phenoxy-5-methylsulfonylbenzoic acid the corresp ...19761255664
assay of proteins in the presence of interfering materials. 19761259145
tritiated thymidine labeling index of benign and malignant human breast epithelium.38 specimens of benign breast tissue from young women and 92 primary breast carcinomas were evaluated for tritiated thymidine ([3h]tdr) labeling index (tli) by in vitro pulse labeling. the tli on nonneoplastic, terminal breast ducts was significantly higher during the latter half than during the first half of the menstrual cycle (p less than 0.001), and a geometric mean tli of 1.5 during the latter half of the cycle is consistent with approximately 47% turnover of these cells during the menstrua ...19761263520
cns glial scar tissue: a source of molecules which inhibit central neurite outgrowth. 19921287723
effect of haemophilus somnus on phagocytosis and hydrogen peroxide production by bovine polymorphonuclear leukocytes.the interactions between bovine polymorphonuclear leukocytes (pmns) and the bacterium haemophilus somnus are known to be complex. in this paper, we evaluated the effect of h. somnus on pmn function using a flow cytometric (fc) technique that simultaneously determined the extent of phagocytosis and hydrogen peroxide production by pmns, as well as using conventional techniques, such as the nitroblue tetrazolium (nbt) and chemiluminescence assays, to analyse the pmn respiratory burst. results from ...19921291842
detection of rabbit haemorrhagic disease virus antigen in tissues by immunohistochemistry.formalin fixed liver, spleen, kidney, heart, lung, duodenum and appendix tissues from nine rabbits, experimentally infected with rabbit haemorrhagic disease virus (rhdv), were investigated for evidence of rhdv antigen by the direct avidin-biotin peroxidase complex immunohistochemical method. in all the rabbits examined, rhdv antigen was detected in degenerative and necrotic hepatocytes of the liver tissues. the area involved coincided with histopathological lesions on serial liver sections. the ...19921320285
saprophytic and keratinophilic fungi isolated from desert and cultivated soils continuously exposed to cement dust particles in egypt.forty soil samples collected from desert (uncultivated) and cultivated soils, exposed continuously to cement dust were screened for their content of saprophytic and keratinophilic fungi using the hair baiting technique and the dilution plate method. using the hair baiting technique, 21 genera and 31 species were collected from 20 samples of each of desert (15 genera and 21 species) and cultivated (17 genera and 24 species) soils, on sabouraud's dextrose agar. these included chrysosporium keratin ...19921325092
monitoring of the neuromuscular transmission by electromyography (i). stability and temperature dependence of evoked emg response compared to mechanical twitch recordings in the cat.the stability over time and the effect of muscle temperature change were evaluated for the evoked compound emg and for the mechanomyogram of the tibialis anterior muscle of 7 anaesthetized cats. both emg areas and amplitudes were recorded. during stimulation for 3 h with 0.1 hz (one leg) and train-of-four (tof) (the other leg), the emg was stable while the mechanomyogram initially increased 35-50% in the first 7-8 min and then decreased 19-22% and 5-8% over the first and second 1.5-h period, res ...19921325093
differential effect of griseofulvin on interferon-gamma-induced hla-dr and intercellular adhesion molecule-1 expression of human keratinocytes.interferon-gamma (ifn-gamma) induces major histocompatibility complex (mhc) class ii antigen and intercellular adhesion molecule-1 (icam-1) expression on human epidermal keratinocytes. griseofulvin, an extensively used antifungal agent, has been used effectively in the treatment of lichen planus, in which keratinocytes express both hla-dr and icam-1 antigens. in this study, we investigated the effect of griseofulvin on ifn-gamma-induced mhc class ii antigen and icam-1 expression of keratinocytes ...19921356410
changes in the bacterial flora of the upper and lower respiratory tracts and bronchoalveolar lavage differential cell counts in feedlot calves treated for respiratory diseases.serial nasopharyngeal swab and bronchoalveolar lavage cultures were used to estimate changes in the bacterial flora of the respiratory tracts of calves during the first month after arrival in the feedlot. bronchoalveolar lavage (bal) differential cell counts served to evaluate pulmonary inflammatory changes during this period. two groups of calves were studied, one consisting of clinically normal controls (n = 60), the other, of cases (n = 59) which received treatment for respiratory disease (pe ...19921423052
the nysb sund double mutant of dictyostelium discoideum is blocked in the acquisition of non-degradative resistance to the pea phytoalexin pisatin.dictyostelium discoideum amoebae can be induced to acquire a non-degradative resistance to the pea phytoalexin pisatin. the nysb sund double mutant is blocked in the acquisition of this resistance. using parasexual genetics it has been shown that sund is a recessive mutation linked to nysb on linkage group vi.19921426988
ascorbate-dependent capacity of dialysed rat liver cytosol to prevent nonenzymatic lipid peroxidation.the capacity of rat liver cytosol to decrease fe/adp ascorbate-induced lipid peroxidation in microsomes was evaluated using the chemiluminescence technique and measuring the formation of thiobarbituric acid-reactive substances (tbars). the inhibiting effect of dialysed cytosol depended on the ascorbate concentration and was highest in the range of 1.0mm. precipitation of cytosolic proteins with ammonium sulfate at 53% saturation yielded an active antioxidative fraction. gel-filtration on sephade ...19921476660
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