| interactions between viruses and bacteria in patients with chronic bronchitis. | the possibility that viral infections of the respiratory tract might predispose to bacterial colonization or infection was studied in 120 patients with chronic obstructive pulmonary disease and 30 control subjects; these individuals were observed for seven years. the ratio of the number of observed to the number of expected associations between viruses and bacteria was 2.43 (p = 0.037) for the pair influenza virus and streptococcus pneumoniae and was 2.06 (p = 0.056) for influenza virus and haem ... | 1976 | 12235 |
| effect of h+ on spontaneous neuronal activity in the surface layer of the rat medulla oblongata in vitro. | the effect of changing extracellular ph (phe) on the spontaneous activity of neurons in brain slices taken from the ventral layer of the rat medulla oblongata was compared to the response of neurons in dorsal slices. in the ventral medulla, more than 50% of the neurons were excited by h+. these neurons were found just lateral to the pyramidal tract between the root of the hypoglossal nerve and the trapezoid body. in the dorsal medulla, low phe caused an inhibition of activity in most neurons, al ... | 1977 | 22840 |
| antibiotic resistance in streptococcus pneumoniae and haemophilus influenzae. | | 1978 | 29689 |
| haemophilus influenzae and haemophilus parainfluenzae in chronic obstructive pulmonary disease. | the importance of nonencapsulated strains of haemophilus influenzae and h. parainfluenzae in the pathogenesis of chronic obstructive pulmonary disease (c.o.p.d.) has been investigated in 150 patients observed at two-month intervals from 1968 to 1975. h. influenzae was distinguished from h. parainfluenzae by demonstrating requirements for both x and v factors. h. influenzae was isolated more often from sputum cultures from patients with severe c.o.p.d. (13.8%) than from patients with mild disease ... | 1976 | 73690 |
| [intestinal control of gastric secretion]. | | 1975 | 85465 |
| [perichordal necroses. contribution to the understanding of the spinal column morphogenesis]. | in 12--15 days old rat embryos and 12 days old mouse embryos vitally stained by acridin orange, a perichordal necrosis appears, showing metameric intensifications at the level of the dense sclerotomites. similar aspects were detected in serially sectioned rabbit and human embryos (6--7 mm c.r. length). the authors correlate the necrotic zones mentioned with the inductive functions of the notochord. | 1978 | 86154 |
| leishmania mexicana and leishmania tropica: cross immunity in c57bl/6 mice. | | 1979 | 88370 |
| effects of arachidonic acid and its metabolites on antigen-induced histamine release from human basophils in vitro. | | 1979 | 90097 |
| [neural secretion of histamine by the gastric mucosa and its effects on gastric motility]. | | 1978 | 90747 |
| the location and expression of idiotypic determinants in the immunoglobulin variable region--iii. expression of the protein 315 and 460 idiotypic determinants in mouse anti-dnp antibodies. | | 1979 | 93694 |
| antigenic analysis of acute hemorrhagic conjunctivitis viruses (enterovirus type 70). | the antigenic characteristics of enterovirus type 70 (ev 70) were investigated by means of cross and kinetic neutralization tests (nt). twelve strains of ev 70 isolated in a period from 1971 to 1976 were analyzed using seven rabbit and one monkey hyper-immune sera. all the strains investigated were found to possess a common and prime variant antigens in varying proportions. accordingly, ev 70 isolates were devided intratypically into three antigenic sub groups; (1) prototype-like (four strain fr ... | 1979 | 94146 |
| cross-reactions between haemophilus influenzae and nineteen other bacterial species. | forty-one different antigens were demonstrated in an antigen preparation obtained by sonication of a haemophilus influenzae (h. influenzae) type b strain, using crossed immunoelectrophoresis and antiserum obtained from rabbits. antigens were characterized by absorption experiments with whole heat-killed bacteria, temperature resistance and protein and polysaccharide staining. cross-reactions between h. influenzae type b and 19 other bacterial species were studied by various quantitative immunoel ... | 1979 | 94235 |
| synthetic antigens iii. antigen-binding cells to interpolymer of styrene and maleic acid psm and sheep red blood cells in mice immunized with psm. | studies on the immune response in mice to a new synthetic antigen interpolymer of styrene and maleic acid (psm) are described. the immune response was measured by determination of antigen binding cells by means of rosette test with psm-coated srbc, an unexpected effect was observed--besides rosette-forming cells for psm, rosette-forming cells and agglutinating antibodies for sheep red cells were found. the results presented in this paper suggest that psm is acting both as an immunogen and a poly ... | 1979 | 94989 |
| analysis of anti-sperm sera for t/t locus-specific antibody. | an objective antiglobulin radioimmunoassay for the analysis of anti-spermatozoa antisera has been used to characterize more than 30 alloantisera. each of these antisera was raised against spermatozoa from mice carrying t/t regin mutations. whilst all of the antisera had considerable activity for mouse spermatozoa, none of them was found to contain antibodies specific for t/t region gene products. a detailed analysis of a single serum revealed that its activity is for antigens which are non-polym ... | 1979 | 95255 |
| the effect of blood on ocular fundus reflectance and determination of some optical properties of retinal blood vessels. | light reflected from 50 micrometer diameter spots on the fundi of two adult rhesus monkeys was measured as a function of wavelength in 10 nm jumps from 400 to 900 nm. the areas measured were a retinal artery and vein, areas of the disk, macula, and retina devoid of visible blood vessels, and the foveola. the eyes of the two monkeys were then exsanguinated, the blood vessels were filled with normal saline, and reflectances of the same spots on the fundi were again measured. the pairs of reflectan ... | 1978 | 96040 |
| [study of the spiral and spindle-shaped formations in cultures of bacillus larvae (white 1906) causing foulbrood in bees]. | the authors have been studying the bacterial diseases of the brood for a fairly long time. american and european foul brood has been studied with the highest attention. cultures of bacillus larvae (white, 1906) were examined both in freshly isolated strains and in collection strains of this micro-organism. in cases of foul brood, the pathological material was found to contain not only the typical rods of b. larvae but also immobile spiral forms which are usually referred to in literature as frag ... | 1978 | 96576 |
| experimental fractures of monkey mandibles. | forty vervet monkey half mandibles, 20 with unerupted third molars and 20 with erupted third molars, were partially embedded in acrylic and loaded in an instron tensiometer. mandibles with unerupted third molars fractured at 15.8 +/- 2.5 kg while those having erupted third molars fractured at 26.4 +/- 4.2 kg. mandibles having unerupted third molars were shown to be significantly weaker than the mandibles with erupted third molar (t = 8.45, p less than 0.001). | 1978 | 98455 |
| gonorrhea detection in posthysterectomy patients. | a retrospective study of women examined at the venereal disease clinic after hysterectomy was made to determine which culture site was most likely to show anogenital neisseria gonorrhoeae infection when the cervix was absent. seventeen of 104 such patients were culture positive for n gonorrhoeae. rates of positivity for our culture sites were as follows: urethral, 17/17 (100%); vaginal, 7/17 (41%); and rectal, 2/17 (12%). | 1978 | 98647 |
| quantitation of particles in the freeze-fractured nuclear membrane after renal ischemia. | changes in the number and sizes of membrane-associated particles have been quantitated in the protoplasmic (p) and exoplasmic (e) fracture faces of the outer membrane of nuclei isolated from the inner cortex following renal ischemia and reflow in the rat. no changes were observed in the inner nuclear membrane. after 20-min ischemia, the number of particles in both fracture faces decreased. with reflow, the total number of particles decreased after both 20- and 60-min ischemia. the partition coef ... | 1978 | 98907 |
| jaundice and breast-feeding among alaskan eskimo newborns. | the course, incidence, and severity of neonatal jaundice was studied in 95 alaskan eskimo infants. breast-fed infants had higher bilirubin concentrations than bottle-fed babies. both groups experienced high bilirubin levels, similar to those previously reported in navajo and oriental infants but greater than those observed in whites and blacks. a marked capacity to inhibit hepatic glucuronyl transferase was observed in breast-milk specimens but only partly accounted for the bilirubin differences ... | 1978 | 99026 |
| amanitins in virus research. | | 1978 | 100081 |
| l-form of pseudomonas aeruginosa. 2. antibiotic sensitivity of l-forms and their parent forms. | | 1978 | 101702 |
| effect of nitroglycerin on vulnerability to ventricular fibrillation during myocardial ischemia and reperfusion. | the effect of nitroglycerin on vulnerability to ventricular fibrillation was examined in 44 chloralose-anesthetized dogs. in 19 animals ventricular fibrillation threshold was measured before and during a 10 minute period of occlusion of the left anterior descending coronary artery followed by abrupt release of occlusion. fibrillation threshold was determined using the single stimulus and train of stimuli methods. the influence of nitroglycerin on vulnerability was assessed with and without preve ... | 1979 | 104608 |
| the effect of dl-2-bromopalmitate on the utilization of palmitic acid by rat granular pneumocytes. | the effect of dl-2-bromopalmitate (brpa), an analogue of palmitic acid (pa), on the utilization of this fatty acid by rat lungs was investigated by a combination of anatomic and biochemical methods. the experiments were performed in vitro on two types of preparations, isolated perfused lungs and lung slices. in the isolated lung preparation the substrate reached the lung via the capillaries, in lung slices via the alveolar epithelium. electron microscope autoradiography showed that brpa depresse ... | 1979 | 105465 |
| dual action of adrenergic system on the regulation of thyrotrophin secretion in the male rat. | the effect of graded doses of drugs modifying adrenergic activity on basal and cold-stimulated tsh secretion was studied in male rats. alpha-methyl-p-tyrosine (ampt) (16 h before 30 min cold-exposure), phenoxybenzamine (1 h), ca-fusarate (1 h) and diethyldithiocarbamate (ddc) (1 and 18 h) dose-dependently depressed the cold-stimulated tsh secretion. the effect of reserpine (24 h) was not significant. clonidine (1 h), dihydroxyphenyl-serine (dops) (1 h), noradrenaline (na) (1 h), and l-dopa (1 h) ... | 1979 | 105532 |
| synchronization of eeg activity of male rhesus monkeys macaca mulatta treated with ovocyclin. | bipolar stainless steel electrodes were stereotaxically implanted in hypothalamus and cortex of six male monkeys. the effect of intramuscular injection of estradiol dipropionate (ovocyclin) in a dose of 10 mg/d was observed on eeg activity on 3 successive days. on the first day, slow waves appeared only in preoptic and on the second day also in posterior hypothalamus. generalized slowing with an increase in amplitude appeared in all the hypothalamic areas and cortex on the third day. this sugges ... | 1979 | 120113 |
| gluconeogenesis in isolated rat hepatic parenchymal cells. ix. differential effects of glucagon and epinephrine on phosphofructokinase and pyruvate kinase. | the isolated hepatocyte preparation (from 24-hour fasted rats) comprised a homogeneous population of intact cells as shown by electron microscopy. homogenates of hepatocytes were incubated for 10 minutes in an ionic buffer solution containing 1.5% gelatin with and without hormones and centrifuged at 27,500 x g for 30 minutes, and the supernatant fractions were assayed for enzyme activities. hexokinase activity was absent, although it was easily detectable in the same fraction of intact liver. th ... | 1976 | 135135 |
| muscle stretch and chemical muscle spindle excitation: effects on renshaw cells and efficiency of recurrent inhibition. | | 1976 | 137423 |
| 35s-sulphate incorporation into myelin sulphated mucopolysaccharides during rat brain development. | rat brain myelin acid mucopolysaccharides (amps) incorporate 15%, 8%, 5.5% and 4% of total associated 35s-sulphate, 14, 21, 30 and 75 days after birth, respectively. the course of 35s-sulphate incorporation into total rat brain mucopolysaccharides, as well in those from myelin, had a similar feature with peak on the 2nd week and a significant decrease on the 3rd and 4th week postnatally. | 1978 | 149015 |
| macrophage-t cell interactions in the con a induction of human suppressive t cells. | macrophage-t interactions are required for the con a-induced generation of human ts capable of inhibiting pha-induced blastogenesis among autologous pbmc. con a treatment of adherent cell-depleted pbmc, or pbmc recovered after a 7-day incubation in fcs, failed to generate ts. addition of adherent cells to either of these populations restored con a inducible ts. discontinuous density gradient fractionation of adherent cells demonstrated that the required accessory cell was a low density macrophag ... | 1978 | 152792 |
| letter: eb-virus-seropostivie person is susceptible to infectious mononucleosis. | | 1975 | 163963 |
| a rapid purification method of restriction endonucleases from haemophilus strains. | a simple and rapid method of purification of restriction endonucleases from different haemophilus strains is presented. by this method highly purified and stable enzymes can be obtained. separation of different restriction activities present in the same strain is possible. this method was so far successfully used with haemophilus influenzae, haemophilus parainfluenzae and haemophilus aegyptius strains. the main advantages over previously published procedures reside in the simplication of certain ... | 1975 | 166680 |
| adenovirus transcription. ii. rna sequences complementary to simian virus 40 and adenovirus 2dna in ad2+nd1- and ad2+nd3-infected cells. | the genomes of the two nondefective adenovirus 2/simian virus 40 (ad2/sv 40) hybrid viruses, nondefective ad2/sv 40 hybrid virus 1 (ad2+nd1) and nondefective hybrid virus 3 (ad2+nd3), were formed by a deletion of about 5% of ad2 dna and insertion of part of the sv40 genome. we have compared the cytoplasmic rna synthesized during both the early and late stages of lytic infection of human cells by these hybrid viruses to that expressed in ad2-infected and sv40-infected cells. separated strands of ... | 1975 | 169392 |
| new satellitism test for isolation and identification of haemophilus influenzae and haemophilus parainfluenzae in sputum. | a new satellitism test designed to facilitate the isolation and identification of haemophilus influenzae and haemophilus parainfluenzae is described. in the basal medium, nicotinamide adenine dinucleotide is incorporated at a concentration of 0.2 mug per ml, an amount adequate for h. influenzae but not for h. parainfluenzae. two disks are placed on the surface of the medium, one disk being impregnated with 60 mug of hemin and the other with 15 mug of nicotinamide adenine dinucleotide. under thes ... | 1975 | 170304 |
| diadenosine triphosphate splitting by rat liver extracts. | | 1975 | 173305 |
| gene mapping of sv40: the biological activity of specific viral dna fragments produced by cleavage with haemophilus parainfluenzae restriction endonuclease. | | 1976 | 173582 |
| proposed structure of two defective viral dna oligomers produced in 3t3 cells transformed by the ts-a mutant of polyoma virus. | the various oligomeric viral dna species produced at 32 c by two related syblines of ts-a-transformed mouse 3t3 cells were characterized. results from the analysis of the cleavage products observed after digestion with restriction endonucleases from haemophilus parainfluenzae, escherichia coli ri, and haemophilus suis are consistent with the assumption that in both sublines, the major oligomeric component is a dimer from which a segment of different length is deleted. the major oligomeric (27s) ... | 1976 | 176437 |
| chemical modification of simian virus 40 dna by reaction with a water-soluble carbodiimide. | superhelical simian virus 40 (sv40) dna i can be modified with n-cyclohexyl-n'-beta-(4 methylmorpholinium)ethylcarbodiimide (cmc). the reaction produces an increase in the sedimentation velocity of dna i from 21 to 22.5s and a decrease in its buoyant density in cscl from 1.694 to 1.688. a comparable shift in buoyant density is observed in a saturated ethidium bromide-cesium chloride gradient where form ii, which has been exposed to cmc, shows no shift. the cscl-buoyant density data allows us to ... | 1976 | 176461 |
| steroid production by quartered and capsular rat adrenal gland in response to haemorrhage. | 60 min after rapid bleeding (1.5--2.0 per cent of b. w.) both aldosterone and corticosterone production rate by quartered rat adrenals were found to be elevated. however, no difference was observed in the rate of aldosterone and corticosterone production by capsular adrenals of sham operated and hypovolaemic rats. corticosterone production rate by decapsulated adrenals was much more higher after haemorrhage than in the control group. the same alterations could be observed incubating adrenal tiss ... | 1975 | 179800 |
| esr determination of mn++ uptake and binding in mitochondria. | | 1975 | 179871 |
| the process of cholesterol cholelithiasis induced by diet in the prairie dog: a physicochemical characterization. | the rapid induction of cholesterol cholelithiasis in a new experimental model, the prairie dog, has recently been reported by two groups. in this model they were able to induce gallstones in as brief a period as 2 weeks, using a 1.2 per cent cholesterol diet. this unprecedented time intensity or telescoping of the induction process provided a unique opportunity for observation of physicochemical changes occurring rapidly over a short period of time and to correlate these with degree of biliary c ... | 1976 | 180214 |
| the effect of lymphoma and other neoplasms on hepatic and plasma enzymes of the host rat. | considerable thymidine kinase and pyrroline-5-carboxylate reductase activities were found in the plasma of rats bearing a transplanted lymphoma; neither activity was detected in plasma of hosts carrying hepatic, renal, mammary, or submaxillary gland tumors. all host livers exhibited signs of biochemical immaturity as indicated by the appropriate increases or decreases in the concentrations of the nine enzymes measured. the extent and time schedule of the changes in host liver varied with the enz ... | 1977 | 187334 |
| immunologic identification of epstein-barr virus early antigen in a p3hr-1 cell extract. | we extracted the epstein-barr soluble antigen (ebsa) from the p3hr-1 human lymphoid cell line, which carries the epstein-barr virus (ebv), after p3hr-1 cells were activated with 5-iodo-2'-deoxyuridine. ebsa was identified as the early antigen (ea) complex by immunodiffusion and blocking immunofluorescence tests with high-titered human antiserum to ea. the identity of the ea complex was confirmed with antiserum to ea prepared in rabbits and adsorbed to assure its immunologic specificity. the ea w ... | 1976 | 187767 |
| human papillomavirus dna: physical mapping of the cleavage sites of bacillus amyloliquefaciens (bami) and haemophilus parainfluenzae (hpaii) endonucleases and evidence for partial heterogeneity. | the dna of human papillomavirus (hpv) obtained from a pool of plantar warts is cleaved by bacillus amyloliquefaciens (bami) and haemophilus parainfluenzae (hpaii) restriction endonucleases at one and four specific sites, respectively. these sites were localized on the previously established cleavage map of hpv dna, using the hind, hindiii, hpai, and ecori endonuclease restriction sites as reference. the four hpaii sites were mapped, clockwise, at 1.4, 41.1, 44.3, and 52.8% of the genome length f ... | 1977 | 191644 |
| regulation of staphylococcal enterotoxin b. | the effect of glucose and the glucose analogues 2-deoxyglucose and alpha-methyl-glucoside on the synthesis and regulation of staphylococcal enterotoxin b was examined. the attenuating effect of glucose on staphylococcal enterotoxin b synthesis was observed. however, when this effect was examined with analogues of glucose, contradictory responses were seen. alpha-methylglucoside had a slight stimulatory effect on enterotoxin production and other extracellular proteins, whereas 2-deoxyglucose mark ... | 1977 | 193794 |
| acute interstitial pneumonia [proceedings]. | | 1977 | 193807 |
| haemophilus parainfluenzae infection of the central nervous system. a report on two infants. | two cases of infection of the central nervous system (cns) with haemophilus parainfluenzae--a 12-month-old girl with meningitis and a 17-month-old girl with brain abscess--are reported. both infants had long-standing upper respiratory infection before cns disease. both recovered after treatment. | 1977 | 198875 |
| [kinetics of production of collagenase, esterase and elastase by human and soil strains of "entomophthora coronata" (author's transl)]. | a comparative study was made of the production of extracellular proteolytic enzymes, which were originated from two different strains, one pathogenic and one saprophytic, of e. coronata in stable culture at 30 degrees c. quantitative differences were found: the maximal activity of the three enzymes (collagenase, esterase, elastase) produced by the strain isolated from soil was always lower than that observed with the human strain. | 1978 | 211891 |
| orbiviruses of the kemerovo complex and neurological diseases. | | 1978 | 214685 |
| effects of swab materials and transport media on aujeszky's disease virus. | the effect of swab materials on the recovery of aujeszky's disease virus from various transport media held at 4 degrees c was investigated over a five day period. no significant loss in infectivity was found in control preparations, approximately 50 per cent of infectivity was recovered from fluids containing applicator wire and approximately 10 per cent from fluids containing polyester fibre or cotton wool. virus recovery from fluids containing wooden applicator sticks ranged from no virus reco ... | 1978 | 214836 |
| radiometric detection of haemophilus in simulated blood cultures. | the radiometric detection of various haemophilus species was studied in simulated blood cultures and in blood culture media without added blood, but supplemented with nicotinamide-adenine dinucleotide (nad) or hemin, or both. haemophilus aphrophilus was the only species studied that was radiometrically detectable without added blood or nad. all other species studied (haemophilus influenzae, haemophilus parainfluenzae, haemophilus haemolyticus, and haemophilus parahaemolyticus) required either ad ... | 1979 | 218444 |
| a simple biological method for detecting streptococcal nicotinamide adenine dinucleotide glycohydrolase. | a biological method for detecting streptococcal nicotinamide adenine dinucleotide glycohydrolase (nadg) is presented, based on its ability to inhibit the growth of haemophilus parainfluenzae. three hundred clinical isolates of beta-haemolytic streptococci were tested. all isolates producing nadg belonged to lancefield's group a, c, or g. | 1979 | 224080 |
| reactivity of platelets with different collagens: overlook. | | 1978 | 262325 |
| structure of a promoter for t7 rna polymerase. | we have determined the nucleotide sequence of a hpa ii restriction fragment of the phage t7 dna containing a promoter for the phage-specified rna polymerase. (hpa ii is a restriction endonuclease from haemophilus parainfluenzae.) mapping of the hpa ii restriction fragments on the t7 genome shows this promoter to be the second of tandem promoters separated by approximately 170 base pairs that begin transcription by the t7 rna polymerase at approximately 15% of the genome. features of the sequence ... | 1977 | 270669 |
| microbiota of gingivitis in man. | a study on the predominant cultivable microorganisms inhabiting gingival crevices affected with a chronic gingivitis was carried out using the roll tube culture technique. samples were obtained from nine individuals 25--42 years of age. gram-positive rods make up 29.1% of the isolates and included mainly actinomyces naeslundii, actinomyces israelii, and actinomyces viscosus. streptococcus mitis and streptococcus sanguis together made up 26.8% of the cultivable organisms. peptostreptococcus avera ... | 1978 | 276916 |
| [the effect of methyl-methacrylate monomer on l-cell metabolism]. | the total serum protein synthesis, amino acid assimilation, rate of cell division, and dna synthesis with various concentrations of methyl methacrylate monomer in medium was determined in a culture of l 929 fibroblasts of the mouse. dna synthesis was inhibited after 12 hours of incubation. the normal course of cell division was completely supressed with a concentration of 3.2 . 10(-2) mol/l. a decrease in protein synthesis was observed after 24 hours of incubation. this decrease may be considere ... | 1979 | 284916 |
| isolated congenital asplenia: an occult case of overwhelming sepsis. | | 1979 | 312008 |
| biotypes of haemophilus encountered in clinical laboratories. | the biochemical characteristics of 464 strains of haemophilus influenzae and 83 strains of haemophilus parainfluenzae isolated over an 18-month period are described. of 22 characteristics obtained, only 6 were necessary to biochemically identify and biotype the isolates. the key substrates or tests were urease, ornithine, indole, o-nitrophenyl-beta-d-galactopyranoside, sucrose, and xylose. five biotypes of h. influenzae and four of h. parainfluenzae were commonly recognized. some strains were en ... | 1979 | 315964 |
| haemophilus parainfluenzae and influenzae endocarditis: a review of forty cases. | two cases of bacterial endocarditis caused by haemophilus parainfluenzae are reported with a review of 33 other cases of h. parainfluenzae endocarditis and 5 cases of h. influenzae endocarditis. although h. parainfluenzae is usually considered a non-pathogenic microorganism, this review firmly establishes its role as a causative agent in endocarditis. furthermore, several clinical features were noted which were atypical when compared to findings usually present in patients with bacterial endocar ... | 1977 | 321916 |
| major proteins of the escherichia coli outer cell envelope membrane as bacteriophage receptors. | three escherichia coli phages, tuia, tuib, and tuii, were isolated from local sewage. we present evidence that they use the major outer membrane proteins ia, ib, and ii, respectively, as receptors. in all cases the proteins, under the experimental conditions used, required lipopolysaccharide to exhibit their receptor activity. for proteins ia and ii, an approximately two- to eightfold molar excess of lipopolysaccharide (based on one diglucosamine unit) was necessary to reach maximal receptor act ... | 1977 | 330500 |
| the taxonomy and antimicrobial susceptibility of haemophilus species in clinical specimens. | organisms of the haemophilus group isolated from nonrespiratory and respiratory sources were studied taxonomically. all biotypes of haemophilus influenzae and haemophilus parainfluenzae were encountered. however, nearly all h. influenzae from cerebrospinal fluids belonged to biotype i, while nearly all of those from conjunctivae belonged to biotype ii. only two of the 78 biotypable strains of h. influenzae produced beta-lactamase, but there was no other substantial difference in antimicrobial su ... | 1978 | 364976 |
| protein and ribonucleic acid syntheses in heat-damaged and heat-killed escherichia coli. | protein and ribonucleic acid (rna) syntheses were measured in both lethally injured and thermally damaged viable cells after heating at lethal temperatures. immediately after heating, cells were incubated in growth media containing either [14c]leucine or [3h]uracil. the labeled cells were subsequently treated with penicillin. viable cells were shown to lyse, and the intact nonviable cells were collected by centrifugation. the results showed that after heating, protein and rna synthesis were rein ... | 1979 | 374390 |
| characterization of plasmids from haemophilus parainfluenzae and haemophilus haemolyticus. | | 1979 | 384428 |
| transfer of a plasmid-specified beta-lactamase gene from haemophilus influenzae. | a number of ampicillin-resistant strains of haemophilus influenzae could donate a gene specifying the type iiia (tem) beta-lactamase to haemophilus parainfluenzae, escherichia coli, and pseudomonas aeruginosa. donor strains rapidly lost their ability to transfer ampicillin resistance on storage or subculture. such strains also apparently contained a single species of covalently closed circular deoxyribonucleic acid of contour length 1.2 mum, equivalent to about 2.5 x 10(6) daltons. no species of ... | 1977 | 403856 |
| haemophilus parainfluenzae endocarditis. two cases and review of the literature in the past decade. | | 1979 | 420249 |
| anaphylaxis in guinea-pig peripheral airways in vitro. | the contributions made by histamine, prostaglandins (pg) and slow reacting substance (srs-a) to anaphylactic contractions in isolated guinea-pig lung were investigated. histamine, pgf2alpha and srs-a induced isometric contractions in lung parenchymal strips and in tracheal smooth muscle. the effective concentrations of the autacoids were the same in lung strips and tracheas. anaphylactic contractions in lung strips from bovine serum albumin sensitised animals were not affected by mepyramine (5 x ... | 1979 | 421743 |
| haemophilus parainfluenzae mitral valve vegetation without hemodynamic abnormality. demonstration by angiography and serial echocardiography. | the occurrence of haemophilus parainfluenzae endocarditis on a previously normal mitral valve of a drug addict is described. a large mitral valve vegetation was demonstrated by serial echocardiography and cineangiography. the vegetation did not produce hemodynamic abnormalities preventing detection by physical examination. multiple septic emboli to various organs, including brain, resulted in death. the role of serial echocardiography and the levophase of right heart cineangiography in detecting ... | 1979 | 433959 |
| prosthetic valve endocarditis due to haemophilus parainfluenzae biotype ii. | haemophilus parainfluenzae endocarditis is characterized by great variation in the acuteness of presentation, difficulty in isolation of the pathogen, a 50% to 60% incidence of major arterial emboli, and variability of response to therapy. prosthetic valve endocarditis (pve) due to h parainfluenzae biotype ii occurred in a 14-year-old girl with congenital heart disease and a starr-edwards mitral valve prosthesis. management was complicated by a prolonged culture-negative period (eight days), int ... | 1979 | 443217 |
| adult bacteremic haemophilus parainfluenzae infections. seven reports of cases and a review of the literature. | seven cases of adult haemophilus parainfluenzae infections diagnosed by positive blood cultures are compared with cases previously reported in the english literature. three patients had pneumonia, while the others had epiglottitis with meningitis, pharyngitis, arthritis, and endocarditis, respectively. nonendocarditic manifestations of adult h parainfluenzae infection were reported in four other cases. in addition to the diseases of our patients, h parainfluenzae also has been isolated from cere ... | 1979 | 475536 |
| transformation by plasmid and chromosomal dnas in haemophilus parainfluenzae. | | 1979 | 475792 |
| chlamydial genital infections: a growing problem. | | 1979 | 478491 |
| behavioural scoring--how good is the agreement between scorers? [proceedings]. | | 1979 | 497589 |
| an xyy man. | this case report describes a young man with a 47, xyy karyotype who was convicted of arson. he suffered from a cardiac disorder which may well have been part of the xyy syndrome rather than a chance association. his abnormal karyotype was disclosed in court and used by the defence in a plea in mitigation. | 1979 | 497632 |
| spontaneous infected pneumatocoele secondary to chronic otitis media. | a case of spontaneous temporal pneumatocoele secondarily infected by haemophilus parainfluenzae is reported. its relation to the lateral ventricle and to a defect in the tegmen tympani was confirmed by computerized tomography (ct). the possible aetiological mechanisms are discussed. | 1979 | 517180 |
| ampicillin resistant haemophilus parainfluenzae endocarditis. | a case of haemophilus parainfluenzae bacterial endocarditis is described. this is the first reported case of endocarditis caused by ampicillin resistant h parainfluenzae. resistance was not mediated by a beta lactamase. ampicillin therapy had not controlled the infection, but a four-week course of chloramphenicol was curative. several general therapeutic points are discussed. | 1979 | 517570 |
| [substrate affinity of erysipelothrix rhusiopathiae neuraminidase for kappa-casein]. | | 1979 | 525455 |
| antimicrobial susceptibility of haemophilus parainfluenzae. | fifty random clinical isolates of haemophilus parainfluenzae were tested for their susceptibility to 10 antibiotics by a microtiter broth dilution method. three of the strains tested were resistant to ampicillin, whereas eight were resistant to tetracycline. all strains tested were susceptible to chloramphenicol, kanamycin, gentamicin, cephalothin, and colistin. the ranges of minimal inhibitory concentrations for the three remaining antibiotics were: 0.5 to >/=128 mug of penicillin g per ml, 0.0 ... | 1977 | 587028 |
| mechanism of transferable resistance to chloramphenicol in haemophilus parainfluenzae. | a clinical isolate of haemophilus parainfluenzae resistant to chloramphenicol and tetracycline transferred both cam and tet determinants to escherichia coli k-12 during mixed cultivation on solid media irrespective of the selection employed. the doubly resistant transconjugant was found to contain levels of the enzyme chloramphenicol acetyltransferase (cat) comparable to those found in r plasmid-bearing chloramphenicol-resistant enteric bacteria. purification of cat from the transconjugant was a ... | 1978 | 646351 |
| the infected mitral valve: floppy mitral valve syndrome complicated by haemophilus parainfluenzae bacterial endocarditis. | | 1978 | 701942 |
| mspi, an isoschizomer of hpaii which cleaves both unmethylated and methylated hpaii sites. | the cleavage of dna by restriction endonucleases hpaii and hapii is prevented by the presence of a 5-methyl group at the internal c residue of its recognition sequence ccgg. mspi, an isoschizomer of hpaii available from new england biolabs, cleaves dna irrespective of the presence of a methyl group at this position. this enzyme cleaves dna from haemophilus parainfluenzae and haemophilus aphrophilus readily while hpaii and hapii cannot degrade these dnas. practically all hpaii sites in mammalian ... | 1978 | 704354 |
| physical mapping of bacteriophage lambda dna with restriction endonuclease hpai. | the restriction endonuclease from haemophilus parainfluenzae, endor.hpai cleaves lambdaci857s7 dna into 14 fragments. the sizes of these fragments were determined and a physical map was constructed. the ordering of the fragments was carried out using different deletion and substitution mutants of lambda phage, double cleavages with another restriction enzyme, endor.bamhi, and partial protection of individual hpai recognition sites by the antibiotics distamycin a and actinomycin d. hpai produces ... | 1978 | 730055 |
| [nitrofurantoin-test for the differentiation of bordetella bronchiseptica (author's transl)]. | bordetella bronchiseptica is primarily resistant against nitrofurantoin (mic greater than 200 mug/ml), and this feature can be used for the differentiation of the organism from other gram-negative coccobacteria. nitrofurantoin paper disks (300 mug) failed to affect the growth of 150 strains of b. bronchiseptica isolated from different animal hosts, but they produced marked inhibition zones in the cultures of the followingspecies: pasteurella multocida, pasteurella pneumotropica, pasteurella haem ... | 1975 | 809944 |
| bacterial endocarditis due to haemophilus parainfluenzae. | we have evaluated three patients with haemophilus parainfluenzae endocarditis. two of the three had underlying heart disease. all presented with fever, chills and malaise of less than two weeks' duration. mitral valve involvement led to congestive heart failure in two of three cases. treatment proved difficult, despite normally adequate dosages of antibiotics to which the pathogens were sensitive in vitro (ampicillin, 12-20 gm/dag; gentamicin, 3-5 mg/kg/day). two patients were cured; one died. ... | 1977 | 832483 |
| haemophilus parainfluenzae infective endocarditis. | seven young to middle-aged patients with haemophilus parainfluenzae endocarditis are reported. three patients had underlying heart disease and three patients had recent events predisposing for endocarditis. the clinical presentation was subacute or acute and new pathologic murmurs were uncommon. diagnosis was prolonged because of difficulties in isolating the organism. routine subculturing of blood cultures to chocolate agar with incubation in co2 is recommended. a prominent complication, occurr ... | 1977 | 846391 |
| [fulminant sepsis with haemophilus parainfluenzae in a child who had been splenectomized during the neonatal period]. | | 1977 | 847829 |
| haemophilus parainfluenzae in urine. | | 1977 | 875849 |
| occurrence of haemophili in dental plaque and their association with neuraminidase activity. | the mean concentration of haemophili in 31 specimens of plaque was 1.23 times 10(6) per milligram or approximately 4.4% of the viable bacteria present. occurrence of different species was similar to saliva with haemophilus parainfluenzae constituting 87.8%. most haemophili produced neuraminidase and appeared to be primarily responsible for the small amounts of this enzyme in plaque. | 1975 | 1057557 |
| methylase activities from haemophilus influenzae that protect haemophilus parainfluenzae transforming deoxyribonucleic acid from inactivation by haemophilus influenzae endonuclease r. | specific methylases that have the properties of deoxyribonucleic acid (dna) modification enzymes have been isolated from haemophilus influenzae strain rd. two activities ((methylase iia and methylase iii) were found to protect transforming dna of h. parainfluenzae from the action of h. influenzae restriction enzymes. to determine the specificty of the protection, a procedure based on biological activity was developed for the separation and purification of the restriction endonucleases from h. in ... | 1975 | 1079804 |
| characterization of an ampicillin-resistant haemophilus influenzae type b. | a 28-year-old female in denver was found in early 1974 to have frontal sinusitis, osteomyelitis, and bacteremia due to haemophilus influenzae, type b. the minimal inhibitory concentration of ampicillin for this organism was 100 mug/ml and the minimal bactericidal concentration was >100 mug/ml. it was inhibited by chloramphenicol at 0.4 mug/ml. further studies demonstrated that ampicillin and methicillin were synergistic against this organism. it was shown to produce a diffusible beta-lactamase. ... | 1976 | 1084727 |
| haemophilus from the lower respiratory tract of patients with cystic fibrosis. | fifty-six non-haemolytic haemophilus strains were isolated during current bacteriological examinations from material from the lower respiratory tract of 39 patients with cystic fibrosis during a 6-month period. except for six strains which belonged to haemophilus parainfluenzae, all strains were identified as haemophilus influenzae. biotype i of h. influenzae was the predominating taxon (38%) and was especially related to patients with recurrent or prolonged colonization. only two strains were c ... | 1976 | 1086508 |
| progressive demyelination and reparative phenomena in chronic experimental allergic encephalomyelitis. | chronic experimental allergic encephalomyelitis (eae), produced in inbred guinea pigs given a single inoculation during the juvenile period with isologous spinal cord in complete freund's adjuvant, has been studied by light and electron microscopy. most animals showed a delayed onset of nurologic signs from 12 to 68 weeks post-inoculation (pi), while several were asymptomatic up to 74 weeks pi. two animals showed a relapsing clinical course. examination of the spinal cords of all animals reveale ... | 1975 | 1141960 |
| the antiarrhythmic and hemodynamic actions of alpha, alpha-dimethyl-4-(alpha, alpha, beta, beta-tetrafluorophenethyl) benzylamine (mk-251). | alpha,alpha-dimethyl-4-(alpha,alpha,beta,beta-tetrafluorophenethyl)benzylamine (mk-251) has been found to prevent certain types of experimentally induced ventricular arrhythmias and at maximally effective doses possesses substantial hemodynamic safety in contrast to standard antiarrhythmic agents. mk-251 prevented or modified ventricular arrhythmias produced by injection of tetrafluorohexachlorobutane into the coronary artery of dogs and baboons. in dogs, the dose estimated to prevent 80% of the ... | 1975 | 1151767 |
| cleavage of adenovirus-5 dna by an endonuclease from haemophilus parainfluenzae. | | 1975 | 1175785 |
| [effect of x-rays on human adult skin explants]. | | 1975 | 1233920 |
| renaturation of bacteriophage lambda dna. determination of the optimal renaturation conditions using a single-strand-specific dnase and alkaline-sucrose-gradient assay system. | reannealed hybrid molecules of wild-type bacteriophage lambda dna were prepared in aqueous solutions of formamide at a variety of nacl concentrations at both room temperature ( 22 degrees c) and 37 degrees c. treatment of the hybrid dna molecules with the single-strand-specific nuclease s1 from aspergillus oryzae followed by alkaline sucrose gradient sedimentation was used to monitor the extent and fidelity of hybridization. the optimal renaturation conditions at room temperature were found to b ... | 1976 | 1248479 |
| quantitative correlations between chemical structure and affinity for acetylcholine receptors. | the affinity constants (log k, pa2) of 128 quaternary ammonium compounds belonging to several different series have been correlated linearly with the hydrophobicity (pir) constant, the dipole moment (mur), and the number of hydroxyl groups (noh) of the side chain; the dependence on the hydrophobicity constant of the quaternary ammonium head (pi-n identical to) is shown to be parabolic. a correlation coefficient of 0.96 is obtained for all the compounds using only 4 independent variables (6 terms ... | 1976 | 1248503 |
| differential regulation of mrnas encoding three protein-tyrosine phosphatases by insulin and activation of protein kinase c. | protein-tyrosine phosphatases (ptpases) play an essential role in the control of signalling through phosphotyrosine pathways. since little is known about the regulation of these enzymes, we examined the effect of insulin and phorbol 12-myristate 13-acetate (pma) treatment of well-differentiated rat hepatoma (fao) cells on the expression of mrnas encoding three major ptpase homologs in liver: ptpase1b, an intracellular enzyme with a single conserved ptpase domain, and two tandem-domain, transmemb ... | 1992 | 1280135 |
| myocardial protection by retrograde cardioplegic perfusion in the presence of acute coronary artery obstruction. an experimental study. | to investigate retrograde delivery of cardioplegic solutions as a means of enhancing myocardial protection in the presence of coronary artery occlusion, a two-part experimental model was devised. in part 1 (in vitro) the possibility of retroperfusing the entire myocardium during acute occlusion of the left anterior descending artery (lad) was assessed. in part 2 (in vivo) acute lad occlusion was performed in dogs, and during 2 hours of aortic cross-clamping crystalline cardioplegic solution was ... | 1992 | 1287835 |
| assessment of the lifetime accumulated cadmium intake from food in kempenland. | research in 1984 indicated that the cadmium body burden was higher in a village where the soil is contaminated with cadmium (luyksgestel) than in a control village (zeeland). the distribution of kidney function parameters also differed between the two villages. the aim of this study is to estimate the lifetime accumulated cadmium intake from food for the people from both villages. various data sets describing dietary patterns in the netherlands were used. the assessed average lifetime accumulate ... | 1992 | 1287841 |
| [clinical studies on cefprozil granules]. | cefprozil granule preparation was administered orally to 16 patients (ages ranging 8 months to 9 years and 6 months) with pediatric bacterial infections at daily dose levels between 29.4 and 35.7 mg/kg divided into 3 or 4 doses. the following results were obtained. 1. sixteen patients including 5 with pharyngitis, 3 with tonsillitis, 3 with lacunar tonsillitis, 2 with pneumonia, 2 with contagious impetigo and 1 with scarlet fever were treated. clinical effects were excellent in 9 cases and moder ... | 1992 | 1289582 |