| bacteriologic diagnosis of acute pneumonia. comparison of sputum, transtracheal aspirates, and lung aspirates. | | 1976 | 521 |
| 'meningitis by the score'. | | 1975 | 664 |
| current status of treatment of pneumonia. | proper treatment of pneumonia is dependent upon a correct diagnosis. pneumonia may be due to infectious agents, allergic phenomena, or chemical causes. treatment regimens are outlined for the various types of pneumonia--pneumococcal, staphylococcal, fungal, and pneumonia due to gram-negative and anaerobic gram-negative bacilli, to blastomyces dermatitidis, and to the parasite pneumocystis carinii. in discussing current concepts of treatment, several well-known methods are emphasized, as well as ... | 1975 | 792 |
| comparative study of virological infections in asthmatic and nonasthmatic children. | the author shows complex analyses: clinical, laboratory, x-rays, bronchoscopical, bronchographical and measuring lung function tests as well as the serological examinations in blood serum of both groups of asthmatic and nonasthmatic children with virological infection. the calculation of statistically significant differences between the various diagnostical results of both groups has confirmed that in asthmatic children virological infection of the respiratory tract, pathological findings in x-r ... | 1975 | 884 |
| acute otitis media. a clinical bacteriological and serological study of children with frequent episodes of acute otitis media. | a series of episodes of acute otitis media was studied with reference to bacterial findings and specific serological responses in 48 children with histories of frequent episodes before. d. pneumoniae and h. influenzae were the most frequently isolated pathogens. re-isolations after therapy were often made in episodes with slow healing or therapeutic failure. most children harboured pathogens in nasopharynx even when they had no signs of respiratory tract infections. homologous relapses were seen ... | 1975 | 885 |
| editorial: bronchiectasis today. | | 1975 | 1138 |
| efficacy of doxycycline in acute infections of the lower respiratory tract. | | 1976 | 1210 |
| the influence of bacterial superinfection on the clinical course of influenza. studies from the influenza epidemics in stockholm during the winters 1969-70 and 1971-72. | during two epidemics of influenza a infection in stockholm 1969-72, 249 cases were selected for a study on the effect of bacterial superinfection. bacterial involvement was demonstrated through cultures and serologic reactions. the occurrence of c-reactive protein in increased amount in serum was significantly more common in the group which had the strongest indication of bacterial infection. an increased duration of fever, and a higher incidence of pneumonia, leukocytosis and erythrocyte sedime ... | 1975 | 1847 |
| evaluation of the antibiotic effect of treatment of maxillary sinusitis. | as the effect of antibiotic treatment of maxillary sinusitis has been questioned, the elimination of bacteria from sinus secretions was studied during antibiotic treatment. penicillin v, azidocillin, tetracycline or doxycycline was administered to 54 patients with maxillary sinusitis. samples of sinus secretion were aspirated both before treatment and 2-3 days after the onset of treatment. when the antibiotic concentration was below the upper limit of mic for sensitivity group 1, bacterial growt ... | 1975 | 1848 |
| proceedings: long-term therapy with antibiotics in chronic bronchitis. | longterm therapy of chronic bacterial bronchitis assumes two forms: (a) therapy of acute exacerbations, and (b) continuous longterm prophylaxis, chiefly during the 4-7 winter months. longterm prophylaxis should be confined exclusively to patients with two or more severe annual exacerbations. the commonest pathogens, haemophilus influenzae and pneumococci, are usually sensitive to ampicillin and amoxycillin, cotrimoxazole (bactrim or eusaprim) and tetracyclines. | 1975 | 2971 |
| concentrations of bacteria in cerebrospinal fluid of patients with bacterial meningitis. | concentrations of bacteria in cerebrospinal fluid ranged from 4.5 x 10(3) to 3 x 10(8) colony-forming units/ml in 27 patients with bacterial meningitis before antibiotic therapy and from 4 x 10(1) to 1.4 x 10(6) cfu/ml in four patients after one to two days of antibiotic therapy. all patients with persistent positive cultures had pretreatment concentrations of 10(7) cfu/ml or greater. a significant association was observed between cerebrospinal fluid lactic acid dehydrogenase activity and concen ... | 1976 | 3635 |
| the role of some microorganisms in the pathogenesis of non-specific bronchopulmonary infections. | | 1976 | 3770 |
| bactericidal activity and pharmacology of flucloxacillin. | flucloxacillin, a recent addition to the group of isoxazolyl penicillins, was studied in vitro and in normal volunteers. the bactericidal activity of the drug against most strains of gram-positive bacteria including penicillin-resistant staphylococcus aureus was similar to that of oxacillin and approximately fourfold greater than that of cloxacillin. each of the three penicillins was administered orally to a group of ten volunteers for eight days in a dose of 500 mg four times a day. the mean co ... | 1976 | 3969 |
| in vitro susceptibility studies with josamycin and erythromycin. | the in vitro activity of josamycin and erythromycin against five bacterial species was compared. in general, erythromycin was slightly more active by weight than josamycin, although both agents had a similar range of activity. | 1976 | 4012 |
| counter-immunoelectrophoresis in the diagnosis of meningoencephalitis by diplococcus pneumoniae and hemophilus influenzae. | the presence of antigen of d. pneumoniae and h. influenzae was detected by counter-immunoelectrophoresis (cie) in 113 lcr of children with central nervous system (cns) infection (17 viral, 70 bacterial and 6 tuberculous). from 41 normal children spinal fluid was obtained and used as control. precipitation band was not observed in normal children cases of viral and tuberculosis meningitis. in 21 cases of bacterial meningitis, d. pneumoniae and h. influenzae was isolated in six cases each. in six ... | 1976 | 4042 |
| immunology and microbiology in acute otitis media. | various immunological parameters were measured in serum, middle ear fluid (mef), and lymphocytes from peripheral blood and mef of infants with acute otitis media due to s. pneumoniae or h. influenzae. approximately half of 131 patients had ige specific antibody to the infecting bacterium as determined by the indirect fluorescent antibody (ifa) technique. seventy-one percent of these ige positive patients had ige specific antibody in the mef. total ige concentration was found to be from an averag ... | 1976 | 5039 |
| otitis media in the newborn infant. | otitis media occurs frequently in newborn infants and often is associated with systemic infection. patients studied at the boston city hospital have provided preliminary data on the otoscopic findings, tympanometric patterns and etiologic agents characteristic of otitis in this age group. | 1976 | 5040 |
| microorganisms in chronic otitis media with effusion. | a total of 175 effusions obtained from 172 patients suffering from chronic otitis media with effusions was examined for bacterial smear and culture. eighty percent showed positive bacterial smear, but only 49% yielded positive bacterial culture. the mucoid effusions had positive cultures in only 37%, whereas the bacterial culture rate was higher in serous (59%) and leukocytic (64%) types. the isolation of common pathogens accounted for about 50% of the isolates, and nonpathogens accounted for th ... | 1976 | 5041 |
| susceptibility of pneumococci and haemophilus influenzae to antibacterial agents. | strains of diplococcus pneumoniae and haemophilus influenzae were tested for susceptibility to numerous antibiotics by a twofold agar dilution method using an inocula replicator. undiluted, fully grown broth cultures were used as inocula for both species, and cultures of pneumococci diluted 1:1,000 were also tested. the antibiotics included most of those in common use in the united states as well as some chemical modifications recently approved and others that are under investigation. the most s ... | 1976 | 5052 |
| gentamicin-susceptibility of various pathogens isolated from clinical materials. | we studied on the antibacterial activity of gentamicin against various pathogens isolated from clinical materials mainly isolated during 1974 and 1975, comparing with other antibiotics. beta hemolytic streptococci, pneumococci and enterococci are less susceptible to gentamicin than staphylococci. staph, aureus and staph. epidermidis resistant to various antibiotics are very susceptible to gentamicin, and no resistant strain to this drug was found. haemophilus influenzae, h. parainfluenzae and h. ... | 1976 | 5619 |
| bacteriological examinations of bronchial secretion in children with non-specific bronchopulmonary disease (author's transl). | one thousand specimens of bronchial secretion from children with non-specific respiratory diseases have been examined bacteriologically. in spite of the complex nature of acute and especially of chronic respiratory disease the role of bacterial infection should not be underestimated. thirty per cent of the specimens were sterile. more than 20 per cent of the bacterial species isolated from bronchial secretion were pathogenic. relatively frequent was the isolation of e. coli and of pathogenic sta ... | 1975 | 5823 |
| bacterial meningitis in infancy and childhood in lusaka (one year prospective sturdy). | in approximately 10,000 admissions in a 12 months period, at university teaching hospital, lusaka 85 cases of meningitis were recorded. the signs and symptoms in these patients do not greatly differ from other similar studies in africa. the commonest organism isolated was pneumococcus. there was high mortality rate which was to a large extent due to parents not bringing their children to hospital early enough for medical treatment to be instituted. this is borne out by the fact that 50% of the c ... | 1975 | 5834 |
| antibacterial activity of eight cephalosporins against haemophilus influenzae and streptococcus pneumoniae. | | 1976 | 6415 |
| a survey of isolates of streptococcus pneumoniae. | over eight months 130 isolates of streptococcus pneumoniae were examined for sensitivity to penicillin, tetracycline, cephalosporin and co-trimoxozole. except in one doubtful case all isolates were sensitive to penicillin. all were sensitive to cephalosporin. 6.9 percent is isolates were resistant to co-trimoxozole. it is suggested that penicillin remains the drug of choice in the treatment of pneumococcal infections. | 1976 | 6927 |
| letter: diagnostic value of the detection of specific polysaccharides by counterelectrophoresis in meningitis in children. 50 cases. | | 1976 | 6946 |
| oxygen-independent inactivation of haemophilus influenzae transforming dna by monochromatic radiation: action spectrum, effect of histitine and repair. | | 1976 | 6978 |
| should fiberoptic bronchoscopy aspirates be cultured? | the reliability of fiberoptic bronchoscopy as a method to study the bacteriology of the lower respiratory tract was tested. the procedure used was suction aspiration through the inner channel after topical anesthesia with lidocaine. to detect contamination by oropharyngeal bacteria, the aspirates were cultured in patients with no evidence of active infection, comparison was made with results of transtracheal aspiration cultures, and the aspirate was tested for the presence of an oral dye marker. ... | 1976 | 7173 |
| immunoglobulins in maxillary sinus secretion. | the immunoglobin pattern was studied in maxillary sinus secretion of 17 patients with maxillary sinusitis. by single radial immunodiffusion, measurable amounts of igm were found in the secretions of 15 patients, and of iga and igg in the secretion of all patients. in purulent sinus secretion, iga levels were significantly lower than in serous secretion. of the total content of iga in sinus secretion, 30% (purulent secretion) and 43% (serous secretion) were calculated to be locally produced, on a ... | 1976 | 7915 |
| otitis media of infancy and early childhood. a double-blind study of four treatment regimens. | a double-blind, randomized trial of four antimicrobial regimens was conducted in 383 infants and children with acute otitis media. the drugs used were penicillin v, amoxicillin trihydrate, erythromycin estolate, and erythromycin estolate with trisulfapyrimidines. aspiration of middle ear fluid for culture was done before treatment and repeated during treatment if fluid persisted. etiologic bacteria were most commonly pneumococci (31%) or haemophilus sp (22%), and an additional 5% of patients had ... | 1976 | 8980 |
| immune response to acute otitis media: association between middle ear fluid antibody and the clearing of clinical infection. | clearing of the middle ear fluid in patients with acute otitis media due to streptococcus pneumoniae or haemophilus influenzae was significantly associated with the presence and concentration of specific antibody in the middle ear fluid at the time of diagnosis. | 1976 | 9424 |
| bacteriology and antibiotics in acute suppurative otitis media. | one hundred and forty-seven patients with acute suppurative otitis media, were divided into three groups and treated with antibiotics (azidocillin, ampicillin, and cephalexin). the therapeutic effect was assessed bacterioloically by swabbing from the aural discharge and from the nasopharynx on the first, second, third, and seventh day after initiation of treatment. in addition, the concentration of antibiotic in the aural discharge and in the nasopharynx was determined. as compared with other pu ... | 1976 | 9519 |
| bacterial precipitins and their immunoglobulin class in atopic asthma, non-atopic asthma, and chronic bronchitis. | in a study of groups of patients with atopic (extrinsic) asthma, non-atopic (intrinsic) asthma, and chronic bronchitis, no difference could be detected in the numbers having precipitating antibodies against species specific antigens from staphylococcus aureus or streptococcus pneumoniae compared to suitably matched control subjects. precipitating antibodies against species specific antigens from haemophilus influenzae, demonstrated in this investigation by double diffusion in agar gel, were foun ... | 1976 | 9702 |
| a case of hemophilus influenzae meningitis with proven resistance to ampicillin. case report. | | 1976 | 11171 |
| interactions between viruses and bacteria in patients with chronic bronchitis. | the possibility that viral infections of the respiratory tract might predispose to bacterial colonization or infection was studied in 120 patients with chronic obstructive pulmonary disease and 30 control subjects; these individuals were observed for seven years. the ratio of the number of observed to the number of expected associations between viruses and bacteria was 2.43 (p = 0.037) for the pair influenza virus and streptococcus pneumoniae and was 2.06 (p = 0.056) for influenza virus and haem ... | 1976 | 12235 |
| bacterial meningitis in the adult. | | 1977 | 12560 |
| relation of concentrations of bacteria and bacterial antigen in cerebrospinal fluid to prognosis in patients with bacterial meningitis. | | 1977 | 13301 |
| bacteriological examination of sputum (author's transl). | the aa., emphasizing the importance of ascertain the bronchial source of microorganisms recoverable from sputum, recommend for this purpose the use of properly collected sputum specimens and the application of washing treatment for mucopurulent materials. the aim of the present study has been to verify the effectiveness of mechanical apparatus to homogenize sputum without affecting the viability of resident microorganisms and the usefulness of prior microscopical examination to establish the rat ... | 1976 | 13741 |
| study on the viscolytic activity of the sputum (author's transl). | several mucolytic agents were evaluated on sputum for testing their viscolytic activity and the bacterial tollerance to each of them. proteolytic enzymes (trypsin, pepsin, papain, pancreatin), kj, and dithiothreitol (or its derivatives) were better tollerated by common respiratory pathogens (h. influenzae, d. pneumoniae, klebsiella, etc.) than other mucolytic agents, as acetil-cysteine, cisteamine-hcl, tension active substances, mercaptoethanol, and others. the dithiothreitol showed also one of ... | 1976 | 13742 |
| aerobic flora examination of sputum (author's transl). | the routine bacteriological test of expectorate, except for mycobacteria, is usually unsatisfactory. there is a need of standardization which results in the present paper from a comparison between the data obtained by two different laboratories on the same samples. it is possible to achieve reasonable and uniform results establishing a uniformity of some procedures, namely; collection of specimens, homogenization, number and type of media, interpretation of data and so on. | 1976 | 13743 |
| acute bacteremia in asplenic renal transplant patients. | four cases of overwhelming bacteremia were observed in asplenic renal transplant patients 12 to 20 months after transplantation. the bacteriologic findings and presentation of these infections are characteristic of post-splenectomy sepsis reported in nontransplant patients. it is suggested that the absence of the spleen, more than immunosuppression with azathioprine and prednisone, predisposes to these late, uncommon infections after transplantation. | 1977 | 16144 |
| physiology of competence in bacteria. | | 1977 | 16417 |
| otitis media in children less than 12 weeks of age. | cases of otitis media in infants under 12 weeks of age were reviewed to delineate the frequency, clinical features, and etiologic agents involved. tympanocentesis was performed in 42 infants, 0 to 5 weeks of age, and in 17, from 6 to 11 weeks of age. the most common symptoms were irritability/lethargy (69%), fever (52%), cough (36%), vomiting (21%), diarrhea (20%), tachypnea (20%), and anorexia (18%). associated illnesses were present in 33 (54%) of the patients, the most common being pneumonia ... | 1977 | 17093 |
| the detection of soluble bacterial antigens studied in various pathological substances using counterimmunoelectrophoresis. contribution to diagnosis(151 cases). | examinations for soluble bacterial antigens using counter-immunoelectrophoresis (c.i.e.) was carried out in 151 patients suspected of suffering from various infectious syndrome were successful for s. pneumoniae, h. influenzae b, n. meningitis, sero-group b and d streptococcus. thus meningitis and pneumonia represent those areas in which the technique is particularly useful. apart from its rapidity--result in a hour--c.i.e., in association with bacteriology, makes possible an increase in aetiolog ... | 1977 | 17848 |
| the use of counter-immuno-electrophoresis to identify causative organisms in bacterial meningitis: experience in cape town. | crebrospinal fluid (csf) from 142 patients was tested for the presence of haemophilus influenzae, pneumococcal and meningococcal antigens by counter-immuno-electrophoresis with commercial antisera. group- or type-specific antigen was detected in the csf of 67% of 64 patients with meningitis proved by culture to be due to these organisms, and in 10 of 25 patients with purulent meningitis but negative cultures. no false positive results were obtained in 24 normal csf specimens, or in the csf of 29 ... | 1977 | 17927 |
| bacteremia in hospitalized children. | the results of 6,951 blood cultures taken from hospitalized children are reviewed. one or more organisms grew from 6% (399) of the cultures, of which 189 (two thirds) were considered to represent confirmed bacteremia. the most common organisms associated with bacteremia were haemophilus influenzae, streptococcus pneumoniae, enterobacteriaceae, and staphylococcus aureus. patients with deficient host defenses (newborns, oncology patients) with bacteremia had a higher mortality than normal children ... | 1977 | 18005 |
| bacterial flora of the respiratory tract in chronic bronchitis: comparison of transtracheal, fiberbronchoscopic, and oropharyngeal sampling methods. | | 1977 | 18077 |
| sound spectrographic cry analysis of infants with bacterial meningitis. | | 1977 | 18378 |
| acute purulent otitis media in children older than 5 years. incidence of haemophilus as a causative organism. | it is generally believed that haemophilus influenzae is not commonly a causative agent of otitis media in children older than 5 years of age. we recently studied cases of 58 children, aged from 5 to 9 years, who had acute otitis media. haemophilus species were the causative agents in 36% of cases. this high incidence of haemophilus isolation from the middle ear exudate of these children has important therapeutic implications; antibiotics effective against h influenzae should be employed when dea ... | 1977 | 18616 |
| prognosis of pneumonia: sputum culture and gram stain. | | 1977 | 18694 |
| nuclease detection in sds-polyacrylamide gel electrophoresis. | | 1977 | 18945 |
| bacterial recombination. | the most perspective trends in studying the mechanisms of genetic exchanges in bacteria are discussed. they are the following. 1. comparison of the recombination stages in various biological phenomena such as transformation, transduction (generalized), conjugation (common and single-stranded) and transfection. 2. characterization of genetic determinants and basic enzymes of the recombination process in rec-systems of different bacteria. 3. determination of some peculiar features of the intrageni ... | 1977 | 19345 |
| the microbiology of chronic middle ear effusions in children. | serous otitis media is the most common cause of hearing loss in childhood. traditionally, this entity has been felt to be a sterile process. this study was undertaken to determine the incidence of infected middle ear fluid in patients with asymptomatic middle ear effusions. the external auditory canal, nasopharynx and middle ear fluids of 57 patients undergoing myringotomy were cultured. of 57 patients, 26 had positive cultures; 67% of patients less than 36 months of age had positive culture, wi ... | 1977 | 19659 |
| acute bacterial meningitis at boston city hospital during 12 selected years, 1935-1972. | data are presented on the occurrence of and mortality rate from acute bacterial meningitis at boston city hospital during 12 years between 1935 and 1972 selected in relation to the introduction of potent antibacterial agents. the most frequent causative organisms were streptococcus pneumoniae, neisseria meningitidis, and haemophilus influenzae, but large proportions were caused by other gram-positive cocci and gram-negative bacilli. the greatest reduction in mortality rate after antibiotics beca ... | 1977 | 20479 |
| early interactions of competent bacteria with nucleic acids (author's transl). | | 1977 | 21387 |
| specificity of cleavage by restriction nuclease from bacillus subtilis. | the restriction nuclease from b. subtilis (bsu) which cleaves in the middle of the tetra-nucleotide sequence 5'-ggcc-3' 3'-ccgg-5' has been found to decrease its substrate specificity at high nuclease concentrations. there are special conditions, high ph, low ionic strength, and high glycerol content, which strongly enhance splitting with decreased specificity and also lead to splitting of single-stranded dna. by sequence analyses it is shown that the reduction in specificity of bsu corresponds ... | 1977 | 22478 |
| aerobic and anaerobic bacteriology of acute otitis media in children. | tympanocentesis and aerobic and anaerobic cultivation of the middle-ear fluid obtained was performed through one or both tympanic membranes of 62 children with acute otitis media. aerobic bacteria alone, predominantely pneumococcus and hemophilus influenzae, were isolated from 57% of patients; anaerobic organisms alone, most commonly propionibacterium acnes and peptococcus, from 15%. thirteen percent yielded mixtures of aerobes and anaerobes, and several had multiple aerobic or anaerobic agents. ... | 1978 | 22590 |
| the increasing incidence of ampicillin-resistant haemophilus influenzae. a cause of otitis media. | middle ear exudate was obtained by myringotomy or aspiration from 625 suburban children, aged 1 month to 12 years, who had acute otitis media; bacterial pathogens were isolated from 71%. haemophilus species were isolated from 212 (29%), and streptococcus pneumoniae from 205 (28%). from 1975 to august 1977, the number of haemophilus isolates found to be resistant to ampicillin has appreciably increased. currently, 8% of all cases of acute otitis media in the washington, dc, area are due to h infl ... | 1978 | 22767 |
| meningitis: the influence of routine otolaryngologic consultation on morbidity and mortality in 290 cases. | a prospective study was designed to obtain data on all meningitis patients admitted to a large county communicable disease unit. the epidemiologic and clinical features of 290 cases were analyzed to ascertain the effect of routine o.r.l. consultation on the morbidity and mortality of this disease. the results of physical examination provided current statistics as to the existence of ear, nose, and throat diseases associated with meningitis. | 1978 | 23470 |
| do bacteria mutate to erythromycin resistance? | | 1977 | 23582 |
| exacerbations of chronic bronchitis: exogenous or endogenous infection? | six male patients with chronic bronchitis, who were known previously to have excreted streptococcus pneumoniae and/or haemophilus influenzae, both at the times of exacerbations and during remission, were studied for 43 to 52 months. sputum was examined fortnightly and at the time of exacerbations. strains of strep. pneumoniae were serotyped and those of haemophilus species were typed by antibiograms along with other supporting methods. sera collected before or at the time of an exacerbation and ... | 1978 | 25664 |
| bacteriological findings in the transtracheal aspirate from patients with acute exacerbation of chronic bronchitis. | transtracheal aspirates from 87 patients with acute exacerbations of chronic bronchitis who had received no recent antibiotic treatment were examined. a single bacterial species was found in 83% of positive cultures. predominant pathogens were haemophilus influenzae and streptococcus pneumoniae which occurred jointly or separately in 50% of positive cultures. bacteria traditionally considered as non-pathogenic for the lower respiratory tract also appeared to play an aetiological role. enterobact ... | 1978 | 25845 |
| a quantitative sputum culture method: the significance of the quantity greater than or equal to 10(7)/ml of isolated organisms (author's transl). | | 1978 | 25980 |
| the detection of bacterial antigens by counter-immunoelectrophoresis in n. meningitidis, h. influenzae serotype b, s. pneumoniae infections. diagnostic value and evolutive aspect (in 216 cases) (author's transl). | using counterimmunoelectrophoresis (cie) the authors have assayed for soluble bacterial s. pneumoniae, n meningitidis group a, b, c. h. influenzae type b antigens, biological fluids in 216 patients (meningitis: 136; pneumonia: 76; miscellaneous: 4) during 16 months. because of heterogeneous recruiting (the bacteriology was carried out by different laboratories) the increase in aetiological diagnosis given by cie is only statistically valid for the bacteriologic negative group when blind antibiot ... | 1977 | 26041 |
| antibiotic resistance in streptococcus pneumoniae and haemophilus influenzae. report of a study group on bacterial resistance. | twenty laboratories in england and scotland took part in 1977 in a survey of antibiotic resistance in streptococcus pneumoniae and haemophilus influenzae. in str pneumoniae 59 (6.8%) of the 866 strains studied were resistant to tetracycline and three to chloramphenicol, and one strain showed a decreased susceptibility to penicillin. the prevalence of resistance to tetracycline was lower than that found in a similar study performed in 1975. nine hundred and fifty-two strains of h influenzae were ... | 1978 | 26450 |
| bacterial etiology of otitis media during the first six weeks of life. | tympanocentesis was performed on 70 infants who had otitis media during the first six weeks of life. the bacteria isolated from their middle-ear effusions were streptococcus pneumoniae (13 patients), neisseria catarrhalis (11 patients), hemophilus influenzae (ten patients), enterobacteriaceae (four patients), staphylococcus aureus (four patients), streptococci (groups a and b) (three patients), and pseudomonas aeruginosa (two patients). thirty patients (42.9%) had middle-ear effusions which did ... | 1978 | 26735 |
| purulent meningitis in childhood. | | 1977 | 26858 |
| type-iii allergic reactivity to diplococcus pneumoniae and encapsulated haemophilus influenzae in passively sensitized mice and rats. | | 1978 | 26860 |
| effect of prior antibiotic therapy on concentrations of bacteria in csf. | a prospective study was done to determine the effect of prior antibiotic therapy on concentrations of bacteria in csf at the time of diagnosis. concentrations of haemophilus influenzae type b in csf of partially treated patients were significantly smaller than in csf of untreated patients. this was also true of patients with meningococcal meningitis, but no difference was observed between patients with pneumococcal meningitis. the identification of h influenzae by gram stain of csf was significa ... | 1978 | 27090 |
| immuno-stimulation by a ribosomal vaccine associated with a bacterial cell wall adjuvant in humans. | we have studied a new vaccine of ribosomal nature associated with glycoprotein cell walls from klebsiella pneumoniae which served as an immunoadjuvant. thus vaccine was administered by the aerosol route to working men free of any important disease, especially of respiratory disease. a total of 104 men working for the commissariat à l'energie atomique, all volunteers, were randomly placed into two groups. during the first period, 51 patients (group i) were vaccinated three times a week during 5 w ... | 1978 | 27461 |
| research of the soluble microbial substances in organic fluids for the rapid diagnosis of some infections and particularly of bacterial meningitis (author's transl). | a number of immunological and non-immunological techniques have been recently used to detect soluble microbial substances in body fluids of patients with acute meningitis, bacteremia, and lobar pneumonia. by the immunological methods capsular highly polymerized polisaccharide group- or type-specific antigens of the most common c. n. s. pathogens (n. meningitidis a, b, and c; str. pneumoniae, h. influenzae type b, e. coli k1, mucoid pseudomonas, cryptococcus neoformans) can be detected and quanti ... | 1977 | 28697 |
| bacteriologic flora of aspiration-induced pulmonary infections. | the role of anaerobic and aerobic microorganisms in the genesis of pneumonia or lung abscess in patients with historical, clinical, and radiologic findings suggestive of aspiration was compared to their role in similar patients without these findings. bacterial specimens were obtained by transtracheal aspiration or thoracentesis. anaerobes were isolated in 100% of the patients who were aspiration-prone as contrasted with only 20% of those who were not. isolation of a single species or no growth ... | 1975 | 28705 |
| otitis media in infants less than 12 weeks of age: differing bacteriology among in-patients and out-patients. | | 1978 | 29086 |
| purulent meningitis from a bacteriological viewpoint. | | 1978 | 29383 |
| evaluation of the counterimmunoelectrophoretic (cie) procedure in a clinical laboratory setting. | the counterimmunoelectrophoretic (cie) procedure was evaluated under clinical laboratory conditions to determine its validity and comparability with culture methods. the procedure was further evaluated to determine applicability to a variety of clinical samples. an inexpensive set-up was developed to utilize the cie procedure at bench level. results indicated the procedure to be sensitive in detecting haemophilus influenzae, type b, and neisseria meningitidis (meningococcus), group b. the proced ... | 1978 | 29483 |
| antibiotic resistance in streptococcus pneumoniae and haemophilus influenzae. | | 1978 | 29689 |
| viruses and bacteria associated with acute respiratory illnesses in young children in general practice. | the results obtained and the laboratory methods used for the isolation of viruses and bacteria from malaysian children with acute respiratory illnesses seen in a private clinic are described. of the 65 children studied virus isolations were obtained from 26 children, bacteria from 10 and both virus and bacteria from another 5. the agents isolated were influenza viruses, parainfluenza viruses, adenoviruses, bordetella pertussis, streptococcus pneumoniae, haemophilus influenzae and staphylococcus ... | 1978 | 30173 |
| bacteriology of maxillary sinusitis in relation to quality of the retained secretion. | the bacteriological findings in 200 patients with acute maxillary sinusitis are reported. it is concluded that the sampling technique--by antral aspiration--is highly significant in the evaluation of the bacteriological background of sinusitis, whereas the anerobic transport of the sample seems to be of less importance. by aspiration the purulent secretion can be properly separated from the non-purulent secretion. pneumococci, h. influenzae and anaerobic bacteria can be isolated in about 90% of ... | 1978 | 30255 |
| bacterial meningitis: the beginning of the end. | | 1978 | 30281 |
| antibiotic resistance in streptococcus pneumoniae and haemophilus influenzae. | | 1978 | 30516 |
| the absorption and sputum penetration of doxycycline. | | 1978 | 30746 |
| microbiology of recurrent and chronic otitis media with effusion. | a study was conducted of 274 children who had recurrent acute or chronic otitis media with effusion. forty-five percent of the ears with effusion were found to contain bacteria, and 11% contained bacteria that were "probable pathogens" (s. pneumoniae, h. influenzae, and s. pyogenes). bacteria were also found in 40% of the ears without effusions. the type of organism found did not vary with the age of the patient studied or the season of the year. the significance of these bacteria in the etiolog ... | 1978 | 30809 |
| treatment of acute otitis media of infancy with cefaclor. | the emergence of ampicillin-resistant haemophilus as a clinical problem in otitis media necessitates a search for alternative, effective therapy. an orally absorbable cephalosporin derivative, cefaclor, is equally effective in vitro against ampicillin-susceptible and -resistant haemophilus and against other bacteria that cause acute otitis media. two dosage schedules of cefaclor (40 and 60 mg/kg/day) were evaluated in 95 infants with acute otitis media. bacterial origin was determined by a cultu ... | 1978 | 31084 |
| [the efficacy of a maintenance dose of 100 mg doxycycline (vibramycin) daily in bacterial infections of chronic bronchitis (author's transl)]. | the efficacy and tolerance of a daily maintenance dose of 100 mg doxycycline (vibramycin) was investigated in ambulant patients with chronic obstructive pulmonary disease (copd) and bacterial infection by an open study with clinical, bacteriological and cytological control. the dosage was well tolerated and effective in the elimination of h. influenzae and pneumococci. a higher maintenance dose seems not to be necessary for this type of infections. | 1978 | 31554 |
| [treatment of chronic bronchitis with supristol and a cotrimoxazole preparation--comparative bacteriological and clinical findings, results of a double-blind study (author's transl)]. | in a randomized double-blind study on the treatment of chronic bronchitis, supristol (co-trifamole) was compared with co-trimoxazole. 163 patients participated in the clinical trial that was performed at three different hospitals in accordance with a uniform trial plan. the microbiological investigations were done centrally at a hygiene institute for all three hospitals. the bacteriological results from the 61 patients whose antibiogram revealed sensitive pathogens before starting the therapy de ... | 1978 | 31555 |
| the use of bacteria for the functional characterization of human lymphocyte subpopulations in various lymphoid organs. | in a haemolytic plaque assay staphylococcal strain cowan 1 was shown to induce polyclonal antibody secretion in human blood lymphocytes, whereas haemophilus influenzae and escherichia coli gave low responses. diplococcus pneumoniae and haemolytic streptococci generally did not activate blood cells. all five bacteria could activate spleen, tonsil and adenoid cells both to polyclonal ig secretion and increased dna synthesis. thus blood cell reactivity does not necessarily reflect the response patt ... | 1978 | 31677 |
| serological methods for rapid diagnosis of haemophilus influenzae, neisseria meningitidis and streptococcus pneumoniae in cerebrospinal fluid: a comparison of co-agglutination, immunofluorescence and immunoelectroosmophoresis. | | 1978 | 31678 |
| hr 756, the syn isomer of a new methoxyimino cephalosporin with unusual antibacterial activity. | hr 756, the syn derivative of 7-[(2-(2-amino-4-thiazolyl)-2-methoxyimino)acetamido]cephalosporanic acid, is a new semisynthetic cephalosporin. it was 80 times more active than the anti derivative against beta-lactamase-producing strains of gram-negative bacteria. the range of inhibitory concentrations of hr 756 against gram-negative bacteria, including haemophilus influenzae, susceptible or resistant to penicillins and cephalosporins was from 0.01 to 0.1 mug/ml. this activity was consistently hi ... | 1978 | 31836 |
| [bacterial allergy in asthmatic syndromes]. | | 1976 | 31959 |
| prospects for the prevention of bacterial meningitis with polysaccharide vaccines. | most suppurative infections of the meninges are caused by five bacterial species: escherichia coli, haemophilus influenzae type b, streptococcus pneumoniae, neisseria meningitidis, and group b streptococcus. the immune response of adults to pneumococcal capsular polysaccharides has been studied in great detail and their responses to meningococcal and h. influenzae type b capsular polysaccharides are quite similar. immune responses of adults to e. coli and group b streptococcal antigens are disap ... | 1978 | 31985 |
| twice daily dosage of bacampicillin in chronic bronchitis. a double-blind study. | three groups of patients (total 48) with acute exacerbations of chronic bronchitis were treated orally for 10 days, in a double-blind clinical trial, with bacampicillin (an ampicillin ester) 1600 mg twice daily, 800 mg three times daily and oral ampicillin 1000 mg three times daily. most exacerbations were caused by haemophilus influenzae or streptococcus pneumoniae. clinical and bacteriological results were significantly more favourable in the two bacampicillin-treated groups. both drugs were g ... | 1978 | 32615 |
| purification and properties of a new restriction endonuclease from haemophilus influenzae rf. | haemophilus influenzae rf 232, showing the phenomena of restriction and modification, contains an endonuclease that inactivates in vitro the biological activity of dnas lacking the strain-specific modification. this specific restriction endonuclease has been purified to near homogeneity by a procedure that includes dna-agarose chromatography. this highly purified enzyme requires atp and mg2+ for activity and is stimulated by s-adenosylmethionine. the enzyme seems to cleave dna at well-defined si ... | 1978 | 33045 |
| opportunist lung infections. | | 1979 | 33268 |
| [bacterial polysaccharides--a new generation of vaccines]. | | 1979 | 33301 |
| counterimmunoelectrophoresis of sputum and blood for the diagnosis of chest infections caused by pneumococci or haemophilus influenzae. | in 107 patients with lower respiratory tract infections, counterimmunoelectrophoresis (cie) of blood and sputum, bacterial cultures of blood, sputum and nasopharyngeal secretion, and enzyme-linked immunosorbent assay (elisa) for antibody determination were performed, with special reference to pneumococci and haemophilus influenzae. for pneumococci cie of sputum was superior to culture especially in antibiotic-treated patients. the clinical significance of a positive cie of sputum was supported b ... | 1979 | 33446 |
| longitudinal study of experimentally induced periodontal disease in macaca arctoides: relationship between microflora and alveolar bone loss. | macaca arctoides monkeys develop periodontal disease, and they harbor a periodontopathic indigenous flora largely similar to that of humans. this study showed that various haemophilus isolates and h2o2-splitting asaccharolytic bacteroides melaninogenicus strains constituted major segments of the monkey periodontal microflora. these organisms have not been previously identified among human isolates. furthermore, the present data revealed that asaccharolytic b. melaninogenicus strains increased in ... | 1979 | 33902 |
| diagnosis and treatment: drugs five years later. amoxicillin. | amoxicillin is an aminopenicillin available in the united states only for oral use. it has an antibacterial activity and spectrum similar to that of ampicillin and is destroyed by gram-positive and gram-negative beta-lactamases. it is more active against enterococci and salmonellae than ampicillin, but less active against shigella. it is better absorbed than ampicillin from the gastrointestinal tract with blood levels two to two and one half times those of ampicillin. amoxicillin is an excellent ... | 1979 | 34342 |
| comparison of staphylococcal coagglutination, latex agglutination, and counterimmunoelectrophoresis for bacterial antigen detection. | soluble antigens of haemophilus influenzae type b, streptococcus pneumoniae, neisseria meningitidis, and group b streptococcus were looked for in cerebrospinal fluid, serum, and urine by using the staphylococcal coagglutination test, latex agglutination test, and counterimmunoelectrophoresis. the staphylococcal coaggultination and latex agglutination tests were more sensitive than counterimmunoelectrophoresis in identifying antigens of h. influenzae type b, s. pneumoniae, and n. meningitidis. no ... | 1979 | 34622 |
| evaluation of blood culture procedures in a pediatric hospital. | to determine optimal clinical laboratory techniques for detecting pediatric bacteremia, we studied 7,768 consecutive blood cultures in a 1-year period. blood was inoculated into one vented 50-ml bottle of brucella broth with 0.05% sodium polyanetholsulfonate and one unvented 50-ml bottle of columbia broth with 0.05% sodium polyanetholsulfonate and 0.05% cysteine. bottles were visually examined for growth on days 1 through 7 and blindly subcultured aerobically and anaerobically on days 1, 2, and ... | 1979 | 34623 |
| chromogenic cephalosporin spot test to detect beta-lactamase in clinically significant bacteria. | lactamase production. reacteroides melaniongenicus, 14 | 1979 | 34624 |
| the nasopharyngeal culture in acute otitis media. a reappraisal of its usefulness. | simultaneous cultures of the nasopharynx and middle ear exudate (obtained by tympanocentesis) were obtained from 225 children (mean age, 34 months; median age, 41 months) with suppurative otitis media. a 72% prediction rate for middle ear pathogens was obtained by examining the nasopharyngeal cultures after the strict observance of two essential prerequisites: (1) the nasopharyngeal culture was immediately plated on appropriate solid agar and (2) a semiquantitative method for bacterial enumerati ... | 1979 | 34739 |