| human lung tumor-associated antigens of 32,000 daltons molecular weight. | lung tumor-associated antigens of approximately 32,000 daltons were recognized by the use of sensitive radioimmunoassays and rabbit antisera, one raised against an extract of pooled human malignant lung tissues and another raised against a cell line derived from a human squamous cell carcinoma of the lung. these antigens differ from antigens described previously, including carcinoembryonic antigen and alpha-fetoprotein. the antigens were detected on 13 of 13 lung tumors (of all histologic types) ... | 1979 | 91695 |
| human lung tissue and anaphylaxis:cyclic nucleotide response and prostaglandin synthesis. | | 1979 | 91946 |
| histochemical reactions of gastrointestinal mucosubstances with high iron diamine after prior oxidation and methylation of tissue sections. | high iron diamine reactions after the prior methylation and oxidation of tissue sections with performic acid or potassium permanganate (metox-hid or ox-met-hid) in epithelial mucosubstances and in mucosal mast cells were studied in tissue samples from the human gastrointestinal tract and were compared with reactions with high iron diamine without any pretreatment (hid) and high iron diamine with the prior methylation (met-hid). high iron diamine reactions after the prior oxidation (met-ox-hid, o ... | 1979 | 93103 |
| [allergenic properties of the blood serum of drug allergy patients]. | | 1979 | 93831 |
| study of effectiveness of bleomycin in rat brain tumor model intravenously and intracerebrally. | | 1979 | 94056 |
| studies on fibronectin in the skin. iii. indirect immunofluorescence studies in lichen planus. | fibronectin is a glycoprotein which is responsible for a varity of functions in the human organism, such as mediation of contact between cells and between cells and fibres, opsonic qualities, interaction in the stabilization of fibrin, etc. fibronectin is an important constituent of the ground substance having a special affinity to collagen. in indirect immunofluorescence studies its presence has been abundantly demonstrated in normal human skin, in collagen-rich structures such as the basement ... | 1979 | 94206 |
| behaviour of solute and particle markers in the stomach of sheep given a concentrate diet. | 1. fistulated sheep given a concentrate diet were used to study the behaviour of solute ([51cr]edta) and particle ([103ru]phenanthroline) markers in the stomach under conditions of continuous feeding. 2. an injection of a mixed dose of [51cr]edta and [103ru]phenanthroline was given into the rumen and the time course of marker concentrations in the rumen and the abomasum was recorded. the curves were analysed on the assumption that the stomach of the sheep could be represented as two mixing compa ... | 1978 | 96850 |
| [antimicrobial activities of two strains of streptomyces albus isolated from african soils]. | the antibiotic activity of these two strains of s. albus is facilitated by culture on slices of potatoes. streptomyces extracts show an antibiotic activity against gram-positive and gram-negative bacteria and an antifongic activity aginst nearly all aspergillus. these antimicrobial effects bring hope of a utilization against some mycotoxin pollution, or mold attacks. | 1978 | 96972 |
| [nature of the mutations that determine the ability of bacillus subtilis a-50 to sporulate at high glucose concentrations in the medium]. | the ability of bacillus subtilis a-50 to sporulate in the medium containing high glucose concentrations is caused by at least two mutation types: pts mutations and cat (or tgl) mutations, both of them affecting differently the level of alkaline proteinase synthesis. the decrease of the level of enzyme activity in the case of pts mutation (glur3 mutant) occurs at the expense of glucose transport disturbance. the mutation cat (tgl) (mutant glur5) causes the increase in enzyme synthesis at the expe ... | 1978 | 97172 |
| entry of beta-n-oxalyl-l-alpha,beta-diaminopropionic acid, the lathyrus sativus neurotoxin into the central nervous system of the adult rat, chick and the rhesus monkey. | | 1978 | 97367 |
| fetotoxicity and cataractogenicity of mirex in rats and mice with notes on kepone. | | 1979 | 92402 |
| [retrograde axonal transport of horseradish peroxidase along the striato-thalamic pathways of cats]. | | 1978 | 98719 |
| changes in composition of tears of malnourished children. | | 1978 | 98738 |
| cats as definitive hosts for sarcocystis of sheep. | | 1978 | 98741 |
| [immunological relations between mother and child during pregnancy (author's transl)]. | the relations between the maternal and foetal organisms during pregnancy are partly very complicated and remain inexplicable. blastocyst, trophoblast, embryo and foetus have membrane antigens at a very early stage, and the immunocompetence of the foetus develops already during the second third of the pregnancy period. many non-specific factors are involved in preventing the castingoff reaction of the foetal organism. the trophoblastic tissue is probably of central importance. the focal point of ... | 1978 | 98927 |
| interferon inducing activity of polyinosinic acid. | although poly(i) is generally considered to be inactive as an interferon inducer, we have found several authentic poly(i) preparations to be effective inducers. their interferon inducing ability varied considerably from one cell system to another. in human diploid fibroblasts, primed with interferon and superinduced by cycloheximide and actinomycin d, all active poly(i) samples proved nearly as effective in inducing interferon as poly(i).poly(c). in primary rabbit kidney cell cultures, the activ ... | 1978 | 99486 |
| behavioral measurement measurements of excitability changes in reward sites in the dog: a frequency dependent effect. | | 1978 | 99757 |
| studies on the occurrence of peptococcus indolicus and corynebacterium pyogenes in abscesses in swine, and on the occurrence of pc. indolicus in apparently normal skin and mucous membranes of piglets. | pc. indolicus was isolated from 42.7% and cb. pyogenes from 48.7% of 150 pus-samples from abscesses in pigs (slaughter-house material, table i). in 41 specimens the two organisms were found together. further, pc. indolicus was demonstrated in 22.4% of 290 swabs from apparently normal skin and mucous membranes of piglets (autopsy material, table ii). by gel diffusion analysis the strains of pc. indolicus were referred to the serotypes b, c, d, e, or f. the type distribution (table iii) possibly r ... | 1978 | 98755 |
| investigations of the 131i accumulation in the white male rats thyroid gland during chronic parathion intoxication. | | 1977 | 98413 |
| purification and characterization of allergens from parietaria officinalis pollen. | | 1978 | 101439 |
| evidence that spo0a mutations are recessive in spo0a-/spo0a+ merodiploid strains of bacillus subtilis. | the spo0a locus contains two types of closely linked mutations that block sporulation at stage 0: spo0a mutations (the most pleiotropic of the stage 0 markers) and spo0c mutations. it was previously thought that spo0a mutations were dominant in merodiploids of bacillus subtilis, whereas spo0c mutations were recessive. we have shown that spo0a mutations were recessive when spo0a-/spo0a+ merodiploids were made in the genetic backgrounds of strains that were resistant to antibiotic produced by the ... | 1978 | 97278 |
| suramin: a potent inhibitor of the reverse transcriptase of rna tumor viruses. | suramin--a well-known antitrypanosomal agent--was found to exert a strong inhibitory effect on the rna-directed dna polymerase (reverse transcriptase) activity of several oncornaviruses such as moloney murine leukemia virus, murine rauscher leukemia viruses, moloney murine sarcoma virus and avian myeloblastosis virus. inhibition of enzyme activity was obtained with both endogenous viral rna and (a)n . oligo(dt) as the template-primer. suramin effected a 50% inhibition of the reverse transcriptas ... | 1979 | 92362 |
| chlamydia psittaci: growth characteristics and enumeration of serotypes 1 and 2 in cultured cells. | the growth characteristics of chlamydia psittaci serotypes 1 and 2 (ovine and bovine origin) were studed in mouse l cells. formation of inclusions and yield of infectious progeny for serotype 1 were maximal when host cells were treated with cycloheximide and the ph in the cell culture medium was 7.2-7.4. the number of cells that contained inclusions and the infectivity yield for serotype 2 were maximal when the ph was 6.6-7.0. treatments with diethylaminoethyl dextran and cycloheximide increased ... | 1979 | 94339 |
| relationship of seminal volume to size and disease of the prostate in the beagle. | the seminal volume of young adult beagles was correlated with the size of and disease in their prostates. the ejaculate volume of naturally collected semen increased in a linear manner with prostatic weight in dogs with normal or glandular hyperplastic prostates. this correlation was not observed in the dogs with cystic hyperplasia, in which there was a reduction in volume of 50% in the semen produced for each gram of prostate. there were no significant differences in other seminal characteristi ... | 1979 | 93426 |
| pneumococcal infections and the possible need for a vaccine. | antibiotics and chemotherapeutics have been available for about 40 years, but still bacterial infections constitute some of the greatest problems in medicine. pneumococci causing pneumonia, bacteremia, meningitis and otitis are a leading cause of illness and death. the exact incidence and lethality of pneumococcal infections is not known, however, since they are not reportable diseases in most countries and since microbiological diagnosis is difficult. in the latest years some significant progre ... | 1979 | 93308 |
| analysis of vibrio parahaemolyticus soluble antigens by employing passive hemagglutination. | the passive hemagglutination assay was explored as a sensitive test of immunological reactivity of endotoxin and other antigens prepared from selected strains of vibrio parahaemolyticus. the tannic acid procedure for passive hemagglutination, commonly used with protein antigens, was the only procedure yielding good results with v. parahaemolyticus protein extracts, endotoxins, and related preparations. these results were probably due to the presence of large amounts of protein in the v. parahaem ... | 1979 | 93111 |
| [relations between oxoglutarate transport function and variations of space in rat heart mitochondria (proceedings)]. | | 1979 | 92958 |
| the zinc iodide-osmium (zio) reaction in the central nervous system: localization and relations to functional activity. | the fine structural characteristics of zio reaction was studied in the cerebral and cerebellar cortex and olfactory bulb of the rat and in synaptosomes prepared from rat cerebellar cortex. it was concluded that: 1. organelles of different nerve cell types exhibit different zio reactions provided that the impregnation was carried out under standardized conditions. 2. 6...10 times more synaptic vesicles were stained by zio in the inhibitory terminals than in the excitatory ones. 3. zio positivity ... | 1979 | 92863 |
| macrophage oxygen-dependent antimicrobial activity. i. susceptibility of toxoplasma gondii to oxygen intermediates. | a sensitive method for evaluating extracellular parasite viability was used to determine the in vitro susceptibility of virulent toxoplasma gondii to selected oxygen intermediates. by acridine orange fluorescent staining criteria, toxoplasmas were resistant to up to either 10(-3) m reagent h2o2 or h2o2 generated by glucose-glucose oxidase. in keeping with a lack of sensitivity to h2o2, toxoplasmas contained endogenous catalase (5.7 x 10(-4) baudhuin units/10(6) organisms). the addition of a pero ... | 1979 | 92521 |
| the metabolism and disposition of 3,4,4'-trichlorocarbanilide in the intact and bile duct-cannulated adult and in the newborn rhesus monkey (m. mulatta). | | 1978 | 106490 |
| study on the significance of bronchial hyperreactivity in the bronchus obstruction after inhalation of cat dander allergen. | the role of bronchial hyperreactivity in the process that leads to bronchial obstruction after inhalation of an allergen was investigated. in 30 asthmatic children selected because of a positive skin test to cat dander allergen, we measured the histamine threshold, the reaction after allergen inhalation, the allergen-specific ige concentration in serum, the lowest allergen concentration to which the intracutaneous skin test was positive (skin titer), and the histamine release of leukocytes after ... | 1979 | 92487 |
| [cutaneous leishmaniasis. alcoy: an endemic zone]. | | 1979 | 92178 |
| changes in skin collagen polarization-optical properties after contact burn. | | 1979 | 92128 |
| generation of a fibroblast chemotactic factor in serum by activation of complement. | when serum complement is activated by either the classical or alternative pathways, a factor with an apparent 80,000 mol wt is generated that is chemotactic for human dermal fibroblasts. the origin of this serum-derived chemotactic factor (sdcf) is not known; however, it may be a cleavage product from c5 because it is inactivated by monospecific antiserum to human c5, and it is not generated when the complement system is activated in human serum deficient in c5. sdcf is not chemotactic for human ... | 1979 | 91624 |
| antigenic correlation between rat brain synaptic vesicles and rat bone marrow b lymphocytes. | rabbit anti-rat brain synaptic vesicle serum reacted with thymocytes and b lymphocytes in cytotoxicity and immunofluorescence assays. quantitative absorption analysis revealed that this antiserum contained antibodies specific for antigenic determinants on the surface membrane of a subpopulation of rat bone marrow b lymphocytes. | 1979 | 91533 |
| analysis of antigens in mycobacterium paratubercuolsis. | | 1979 | 90456 |
| the role of p23,30-bearing human macrophages in antigen-induced t lymphocyte responses. | | 1979 | 88270 |
| demonstration and characterization of specific binding sites for factor viii/von willebrand factor on human platelets. | the presence of specific factor viii/von willebrand factor (fviii/vwf) binding sites on human platelets has been demonstrated by using 125i-fviii/vwf and washed human platelets. binding is ristocetin-dependent and increases in proportion to the concentration of ristocetin from 0.2 to 1 mg/ml. binding of 125i-fviii/vwf to platelets can be competitively inhibited by unlabeled human or bovine fviii/vwf, but not by human thrombin, fibrinogen, alpha 2-macroglobulin, equine collagen, or a lectin of ri ... | 1979 | 108291 |
| the puzzle of "urethral syndrome": a possible answer? | 82 strains of slow-growing, co2-dependent, gram-positive organisms have been isolated from the urine of 9 male and 73 female patients. 100% of the men and 93% of the women had urinary symptoms at the time of isolation, and 66% of the specimens showed pyuria. these organisms might account for the urinary symptoms of some patients previously diagnosed as having "urethral syndrome". preliminary data show that, if appropriate antibacterial treatment is given, most of these patients become symptom-fr ... | 1979 | 86778 |
| probenecid-induced increase of 5-hydroxytryptamine synthesis in rat brain, as measured by formation of 5-hydroxytryptophan. | probenecid blocks the efflux of 5-hydroxyindole acetic acid (5-hiaa) from the central nervous system, and has therefore been used for turnover measurements of central 5-hydroxytryptamine (5-ht). this substance also elevates tryptophan (tp) levels in rat brain. in this investigation, the time courses of probenecid and tp levels in rat serum and brain after administration of probenecid were studied. maximal levels of probenecid were reached within 15 min, followed by 50% decrease of serum tp and a ... | 1979 | 108699 |
| cytofluorometric and cytochemical comparisons of normal and abnormal human cells from the female genital tract. | acridine orange staining of exfoliated cells from epithelial tissues facilitates discrimination between normal and abnormal cells: abnormal cells develop highly elevated nuclear fluorescence. comparisons of acridine orange (ao) staining with propidium iodide (pi) or feulgen staining have shown that: (a) pi staining also provides highly elevated nuclear fluorescence from abnormal cells; (b) the distributions of nuclear fluorescence following ao or pi staining were usually not significantly differ ... | 1979 | 86579 |
| immunochemical properties of oligosaccharide-protein conjugates with klebsiella-k2 specificity. i. specificity and crossreactivity of anti-conjugate versus anti-bacterial antibodies. | | 1979 | 86152 |
| [response to catecholamines in rats deficient in essential fatty acids (proceedings)]. | | 1979 | 92240 |
| morphology of freeze-etched treponema refringens (nichols). | the freeze-etch technique was used to study the morphology of treponema refringens (nichols). there is a single band of cytoplasmic fibrils which follows a path in the form of a right-handed helix with a periodicity of 1500 nm around the body of the treponeme just below the cytoplasmic membrane. there are two major fracture planes, one located in the interior of the outer envelope and the second in the interior of the cytoplasmic membrane. the "blebs" or "surface protuberances", which are quite ... | 1978 | 100069 |
| synthesis and biological properties of prostaglandin endoperoxides, thromboxanes and prostacyclins. | | 1978 | 98074 |
| electrophoretic strand separation of long dnas with poly (u,g) in agarose gels. | we have found that binding of poly(u,g) to single-stranded dna decreases its mobility in 0.3% agarose gels. differential binding to the complementary strands of denatured duplex dna provides a simple method for strand separation. the method is shown to work with bacteriophage lambda dna, adenovirus dna and mtdna for tetrahymena pyriformis. in all cases the strand that binds more poly(u,g) in cscl gradients also binds more in gels. the separated strands can be directly blotted from the gel onto n ... | 1978 | 99728 |
| [management of patients with pseudomonas aeruginosa infections]. | | 1978 | 96314 |
| salvizol as an intracanal antiseptic for endodontic use. | | 1978 | 99707 |
| cell-mediated immune response in mice treated with steroidal contraceptives. | the splenomegaly assay (simonsen, 1962) was standardized using different strains of rats and mice. male wistar rat (donor)-female swiss mouse (host) was found to be the suitable combination that could be employed in subsequent experiments to study the potential of contraceptive steroids to alter cmir. the index of splenomegaly appeared to increase in case of mice treated with combination oral contraceptives (ovulen, ovral or enovid). the differences observed, however, neared significance only in ... | 1975 | 55327 |
| [influence of culture on evolution of biological structures in human groups]. | | 1975 | 126716 |
| the diet and feeding behaviour of cercopithecus aethiops tantalus. | the feeding behaviour of representative groups of tantalus monkeys (cercopithecus aethiops tantalus) was observed during 1974-1975 in three habitats in cameroon. observations took place during the wet and dry seasons in sahelian savannah, guinea savannah and farmed forest. the tantalus monkeys were similar to other races of c.aethiops that have been studied in that they were omnivorous and lacked any narrow specialisations of either diet or feeding techniques. the dietary range was similar in al ... | 1978 | 101428 |
| cyanobacterial phycobilisomes. characterization of the phycobilisomes of synechococcus sp. 6301. | a procedure is described for the preparation of stable phycobilisomes from the unicellular cyanobacterium synechococcus sp. 6301 (also known as anacystis nidulans). excitation of the phycocyanin in these particles at 580 nm leads to maximum fluorescence emission, from allophycocyanin and allophycocyanin b, at 673 nm. electron microscopy shows that the phycobilisomes are clusters of rods. the rods are made up of stacks of discs which exhibit the dimensions of short stacks made up primarily of phy ... | 1978 | 101538 |
| direct and utilization of metabolic energy for transport processes within proximal convolution. | | 1975 | 127689 |
| clinical studies on pipemidic acid. | | 1978 | 101691 |
| l-form of pseudomonas aeruginosa. 1. an effective method for the production of stable l-forms. | | 1978 | 101700 |
| [carbon metabolism in methylotrophic bacteria isolated from activated sludge]. | | 1978 | 101747 |
| the fate of transplanted pancreatic islets in the rat. | syngeneic pancreatic islets transplanted into the liver or the spleen reverse streptozotocin-induced diabetes in the rat, but allogeneic islets function only briefly and are rejected. shortly after transplantation, thrombi often form around transplanted tissue, particularly around nonislet tissue that contaminates islet preparations. these thrombi are a source of transient liver injury in recipients of intrahepatic grafts. a few days after transplantation, syngeneic islets injected into the port ... | 1979 | 104625 |
| implications for adult roles from differential styles of mother-infant bonding: an ethological study. | ethological observations of maternal and infant behaviors of nine vervet monkey pairs (cercopithecus aethiops sabaeus) showed the effects of differential styles of early maternal responsiveness on later infant competence. those infants receiving the least amount of maternal responsiveness and the most time-off the mother in the first 3 months of development were more socially competent at 6 months of age. the results are discussed within current ethological "attachment" theories. the detachment ... | 1979 | 105083 |
| allometric radial growth in muscle, comparing fibres with strong and with weak adenosine triphosphatase activity. | a large flock of male and female white turkeys (meleagris gallopavo) was reared for 22 weeks after hatching. at two weeks intervals small groups of birds were removed from the flock and killed. samples of sartorius muscles were taken from the bird nearest the mean weight for its group. transverse frozen sections were tested for atpase activity by calcium method at ph 9.4. fibres were separated into two categories (strong-atpase and weak-atpase) and their mean minimum diameters were measured with ... | 1979 | 161561 |
| polychlorinated biphenyl-induced morphologic changes in the gastric mucosa of the rhesus monkey. | the early morphologic events in polychlorinated biphenyl-induced lesions of the gastric mucosa of immature male rhesus monkeys (macaca mulatta) were studied in serial biopsies taken during consumption of diets containing 3, 10, 30, and 100 mg. per kg. (p.p.m.) of aroclor 1242. the severity of the lesions correlated directly with both the duration and the level of exposure. the first changes were seen after ingestion of 30 and 100 mg. per kg. for 2 weeks; changes were not seen until 10 weeks at 3 ... | 1979 | 106183 |
| [isolation and general characteristics of a group of pseudomonas aeruginosa temperate phages]. | eighteen temperate phages were isolated from 38 natural strains of pseudomonas aeruginosa. the phages belong to five heteroimmune groups according to the ability of lysogenic variants of the strains pao1 and pat2 to exclude the growth of the superinfecting phage. phages of the ii and v immunity groups are serologically similar; the remaining phages are not inactivated by antisera against phages b26 (ii group) and k1338 (v group). prophages of the ii, iv, and v groups are induced by uv for vegeta ... | 1979 | 106221 |
| organ cultures of rat and hamster colon. | human fibrin foam as a matrix for three-dimensional organ cultures was successfully employed for the cultivation of newborn rat and hamster colon tissue. colonic tissue was maintained under different oxygen atmospheres and with various synthetic media. explants of rat and hamster colon, maintained in leibovitz's l-15 medium buffered with hepes in the presence of 5% co2 and air, retained their normal columnar epithelial architecture for 24 days in culture. outgrowth of epithelial cells from colon ... | 1975 | 165141 |
| [xerophytic microorganisms multiplying under conditions close to martian ones]. | the xerophytic cultures bacillus megaterium and mycococcus ruber can grow in the imitated martian conditions. therefore, they are resistant to the extreme factors of the environment: the composition of atmosphere, low pressure, the maximum hygroscopicity of a substrate, periodic freezing-thawing. | 1979 | 106224 |
| [present concepts of ultrastructure of gonococcus]. | | 1979 | 106576 |
| [determinaton of intracellular immunoglobulins by means of immunofluorescence. 1. the standardization of monospecific luminescent antisera against human g-, a- and m-class immunoglobulins in bone marrow preparations from patients with paraproteinemic hemoblastosis]. | to assess the specificity and the activity of fluorescent antisera against human g-, a-, m-classes the authors used in the capacity of a substrate, containing specific antigen preparations, bone marrow cells of patients with paraproteinemic hemoblastosis. the method of making the preparations used permitted sufficiently objective assessment of the activity and specificity of the mentioned monospecific fluorescent conjugates. as revealed, the bone marrow preparations could be stored at -70 degree ... | 1978 | 106607 |
| radical scavenging as the mechanism for stimulation of prostaglandin cyclooxygenase and depression of inflammation by lipoic acid and sodium iodide. | certain radical-trapping reducing agents have been shown to stimulate prostaglandin biosynthesis in vitro (1--6) and to depress phorbol myristate acetate-induced mouse ear edema (16). the increased prostaglandin synthesis resulted from influences on the cyclooxygenase. to ascertain whether these alterations were due to direct interaction with the enzyme or to indirect scavenging of the oxidant released during pgg2 reduction, we report the effects of lipoic acid and sodium iodide. both of these a ... | 1978 | 107544 |
| fat-induced jejunal inhibition of gastric acid secretion and release of pancreatic glucagon, enteroglucagon, gastric inhibitory polypeptide, and vasoactive intestinal polypeptide in man. | the effect of intrajejunal (i.j.) infusion of fat on meal-stimulated gastric acid secretion and release of pancreatic glucagon (pg), enteroglucagon (eg), gastric inhibitory polypeptide (gip), and vasoactive intestinal polypeptide (vip) was studied in seven healthy volunteers. i.j. fat markedly inhibited meal-stimulated acid secretion as compared to a control study with i.j. saline infusion. the acid inhibition was accompanied by augmental plasma concentrations of eg, gip, and vip but not of pg, ... | 1979 | 107575 |
| a three month inhalation toxicity study in the squirrel monkey (saimiri sciureus) with terbutaline sulfate (bricanyl). | a study of the subacute toxicity of inhaled terbutaline sulfate was performed in the squirrel monkey (saimiri sciureus). 3 groups of monkeys were exposed 1 h daily 7 days/week for 3 months to terbutaline sulfate aerosols at concentrations of 0.039, 0.185 and 0.799 mg terbutaline/litre of air respectively. a fourth group was a chamber control receiving air only. the following clinical parameters were evaluated: physical appearance and behavior, weight gain, ophthalmoscopic appearance, electrocard ... | 1978 | 107616 |
| experimental transmission of wuchereria bancrofti to monkeys. | infective larvae of wuchereria bancrofti from laboratory-raised culex pipiens fatigans and aedes togoi mosquitoes fed on human volunteers in jakarta, indonesia (j strain) and kinmen island, china (k strain) were introduced into taiwan monkeys (macaca cyclopis) by subcutaneous inoculation, by foot puncture, or by permitting infected mosquitoes to feed weekly on the monkeys. some animals were splenectomized and others were treated with varying regimens of immunosuppressants. necropsy was done on m ... | 1979 | 107818 |
| mechanism of folate transport in lactobacillus casei: evidence for a component shared with the thiamine and biotin transport systems. | lactobacillus casei cells have been shown previously to utilize two separate binding proteins for the transport of folate and thiamine. folate transport, however, was found to be strongly inhibited by thiamine in spite of the fact that the folate-binding protein has no measurable affinity for thiamine. this inhibition, which did not fluctuate with intracellular adenosine triphosphate levels, occurred only in cells containing functional transport systems for both vitamins and was noncompetitive w ... | 1979 | 108244 |
| microscopic changes in rat tongue following experimental cryosurgery. | histological changes were studied in the rat tongue for varying periods of time up to 14 days following the application of a cryoprobe to the dorsal surface of rat tongue. within minutes of the application, focal subepithelial vesiculation and hyperemia occurred. at 3 h there was evidence of damage to capillary walls, resulting in hemorrhage. arterioles and venules were thrombosed and there were degenerative changes in the muscle layer of their walls. at 6 h ventral epithelium showed evidence of ... | 1979 | 108379 |
| [organization of the veterinary service of a dairy complex]. | | 1975 | 129913 |
| tightness and orientation of vesicles from guinea-pig kidney estimated from reactions of adenosine triphosphatase dependent on sodium and potassium ions. | in order to study the "sidedness" of the ligands of the na+, k+-atpase in the phosphorylation from [32p]atp, tight vesicles were prepared from guinea pig kidney and partially purified by a two-stage sucrose and ficoll gradient centrifugation procedure. these vesicles were derived presumably from plasma membrane fragments resealed after the initial disruption of the cells during homogenization. tightness of the vesicles was estimated according to activation by the nonionic detergent, triton x-100 ... | 1975 | 126864 |
| nuclear proteins of rat liver and of an aminoazo-dye-induced hepatoma. | nuclear proteins of rat liver and rat ascites hepatoma were fractionated by extraction in solutions of different salt concentration and analyzed by sodium dodecyl sulfate polyacrylamide gel electrophoresis. the difference between the electrophorograms of the different fractions of nuclear proteins isolated from liver and from hepatoma was found in the bands which have the same electrophoretic mobility as the main proteins of informofers and are extracted from nuclei at salt concentrations which ... | 1975 | 168162 |
| [prevention of helminthiasis in sheep in kazakhstan]. | | 1975 | 129934 |
| feeding parameters with two food textures after chlordiazepoxide administration, alone or in combination with d-amphetamine or fenfluramine. | chlordiazepoxide (5.0, 10.0 mg/kg) reduced the rate of eating and extended the duration of feeding in a 10 min feeding test. it also reduced the latency to feed. both fenfluramine (1.0 mg/kg) and d-amphetamine (0.25 mg/kg) acted to reduce food intake, but by differing mechanisms. fenfluramine reduced eating rate without affecting eating duration, whilst d-amphetamine reduced eating duration without reducing eating rate. the effects of chlordiazepoxide on feeding parameters were generally additiv ... | 1979 | 111292 |
| [influence of microflora on the metabolism of l-threonine at the level of the rat digestive tract]. | intestinal tissues are found to incorporate l threonine 14cu at faster rate in the absence of microflora. most of the radioactivity of the digestive contents occurs in the tca soluble compounds, except in the coecum and large intestine of the conventional rats where the microflora synthetized its own proteins from the labelled digestive material. free threonine is the main labelled soluble compound in the conventional rats digestive contents. in the other hand, in the germfree rats digestive con ... | 1976 | 134804 |
| [synchronous electric activity with inspiration in the vastus lateralis muscle of the anesthesied dog breathing spontaneously]. | in the dog, under chloralose or pentobarbitone anesthesia and breathing spontaneously, a muscular electrical activity of low voltage synchronous with respiration was observed in m. vastus lateralis. the mean maximum amplitude of this activity is inversely linked with respiratory rate. when the respiratory frequency is equal or exceeds 25 cycles per minute this activity disappears. such a phenomenon seems to be related to the activity of the respiratory centre. | 1976 | 134813 |
| [proceedings: urinary excretion of cyclic amp during expansion in rats]. | | 1975 | 175173 |
| isolation and characterization of actin and myosin from b-lymphocytic guinea pig leukemia cells. | actin and myosin have been isolated from a guinea pig b cell leukemia line, l2c. the m.w. and amino acid compositions of these proteins are similar to actin and myosin from other nonmuscle cell types. l2c actin polymerizes to form filaments and activates the atpase activity of skeletal muscle myosin. actin in crude lymphocyte extracts does not polymerize as well as predicted from the critical concentration of purified lymphocyte actin suggesting that other factors in lymphocyte extracts regulate ... | 1979 | 156229 |
| circular dichroism and ultraviolet absorbance of calf thymus dna in presence of ch3hgoh. | | 1979 | 156470 |
| [specific antibodies in the nasal secretum of children with rs viral affection of lower respiratory pathways (author's transl)]. | | 1979 | 161514 |
| editorial: subunits of myosin. relations to atpase activity and mechanical function of muscle. | under certain conditions the specific atpase activity of myosin of a given muscle can be altered. the cause of this alteration can only lie in the myosin molecule itself. to produce an enzymatic activity of myosin, an interaction between their light and heavy chains is necessary. however, the specific activity appears to be determined mainly by light chains. hence, one ought also to look for a basis of the changed activity in changes of the subunits of myosin. there are strong indications that t ... | 1975 | 128346 |
| [herpesvirus-induced autoantibodies in animals (author's transl)]. | after immunization with autologous testicle cells which were infected with herpes virus hominis type 1 or 2, histologically homogeneous, eosinophilie pas-positive substances could be detected in five out of six rabbits, mainly within the interstitium. these substances have been found by immunofluorescence microscopic techniques to be antibodies against testicle tissue. | 1976 | 183633 |
| progesterone-binding proteins from endometrium and myometrium of sheep uterus: a comparative study. | the binding of tritiated proesterone to the cytoplasmic progestogen receptors from oestrogen-primed sheep endometrium and myometrium has been investigated. the binding characteristics of the progesterone receptors from both sources were determined in the supernatant fractions obtained after high speed centrifugation of the myometrial and endometrial homogenates. high affinity binding proteins with identical association constants for progesterone (1 times 10-9 m-1) were detected in both endometri ... | 1975 | 164095 |
| colloidal iron hydroxide-binding to the surfaces of chick embryo fibroblasts transformed by wild-type and a temperature-sensitive mutant of rous sarcoma virus. | the densities of colloidal iron hydroxide (cih) particles binding to the surfaces of chick embryo fibroblasts were determined before and after transformation with wild type rous sarcoma virus and a temperature sensitive (ts) mutant of this virus. on the basis of in vitro behavior, cells transformed by the ts virus manifest a malignant phenotype at 36 degrees c (permissive temperature) and appear normal at 41 degrees c (non-permissive temperature). at the permissive temperatures there is a signif ... | 1977 | 193866 |
| analogies and differences between reserpine pgo wave discharges and oculomotor phasic activity during paradoxical sleep in the cat. | in the present study the analogies and differences between phasic pgo activity of parodoxical sleep and the reserpine induced pgo waves were investigated. the oculomotor phasic activities in chronic cats were studied. it appeared that the intrinsic organisation of latencies and the appearance of phasic waves in the four structures studied were common to both experimental situations. however the sequential patterns of discharges were different in ps and under reserpine treatment. | 1977 | 195316 |
| synthesis of superhelical simian virus 40 deoxyribonucleic acid in cell lysates*. | in vivo-labeled sv40 replicating dna molecules can be converted into covalently closed superhelical sv40 dna (sv40(i) using a lysate of sv40-infected monkey cells containing intact nuclei. replication in vitro occurred at one-third the in vivo rate for 30 min at 30 degrees. after 1 hour of incubation, about 54% of the replicating molecules had been converted to sv40(i), 5% to nicked, circular molecules (sv40(ii), 5% to covalently closed dimers; the remainder failed to complete replication altho ... | 1975 | 165197 |
| [some aspects of the histoenzymology of the hypothalamo-neurohypophyseal neurosecretory system]. | | 1975 | 167367 |
| the fine structure of the cysticercoid of hymenolepis diminuta. iii. the scolex. | transmission electron microscopy of the scolex of the 8-day-old hymenolepis diminuta cysticercoid demonstrates its resemblance to the scolex of the adult. a syncytial tegument composed of external and internal layers is connected by cytoplasmic extensions. fully developed microtriches are present. furthermore, a basement membrane, muscle layers, and medullary region containing flame cells, nerve tissue, and other cell bodies are observed. of particular interest is the presence of discrete sensor ... | 1975 | 167533 |
| inhalation anesthetics and cytochrome p-450-dependent reactions in rat liver microsomes. | the activities of liver microsomal enzymes were studied in preparations from unanesthetized rats and rats anesthetized for one hour with nitrous oxide, diethyl ether, halothane or chloroform. most of the enzymes studied were cytochrome p-450-dependent oxygenases that hydroxylate endogenous substrates. the other microsomal enzymes, assayed for comparison, included the cytochrome p-450-dependent aminopyrine demethylase, glucose-6-phosphatase, a dehydrogenase, and nadph-cytochrome p-450 reductase. ... | 1975 | 167617 |
| synthetic position 5 analogs of adrenocorticotropin fragments and their in vitro lipolytic activity. | twenty-three analogs of the acth-(4-10)-heptapeptide sequence, which forms the "active core" of adrenocorticotropin (acth) and related hormones, have been synthesized by the solid-phase method. these analogs all contain structural modifications at or near the 5-glutamic acid residue of acth. the peptides were purified to electrophoretic and chromatographic homogeneity. the peptides were assayed for lipolytic activity in an isolated cell system derived from rabbit adipose tissue. in this system, ... | 1975 | 167812 |
| bile salt alteration of ion transport across jejunal mucosa. | the effect of conjugated dihydroxy and trihydroxy bile salts on electrolyte transport across isolated rabbit jejunal mucosa was studied. both taurochenodeoxycholic acid and taurocholic acid increased the short-circuit current (isc) in bicarbonate-ringer solution but not in a bicarbonate-free, chloride-free solution. taurochenodeoxycholic acid was significantly more effective than taurocholic acid in increasing isc. the presence of theophylline prevented the taurochenodeoxycholic acid- and tauroc ... | 1975 | 167840 |
| the effects of hyperlipidemia on lipoprotein metabolism in squirrel monkeys and rabbits. | we studied the metabolism of different classes of lipoprotein in squirrel monkeys and rabbits. lipoproteins were labeled in vivo in donor animals with (3h)leucine and (3h)cholesterol. the rate of disappearance from plasma of recipient squirrel monkeys of the protein moiety of the very low density lipoproteins was rapid, that of high density lipoproteins slow, and the rate for low density lipoproteins was intermediate. the fractional turnover of the apoprotein of low density lipoproteins was slig ... | 1975 | 167856 |
| induction of cystathionase in foetal rat liver explants. effects of dexamethasone, n-6, o-2 -dibutyryladenosine 3,5 -monophosphate and glucagon in vitro. | at the 18th day of gestation and thereafter foetal rat liver explants in organ culture showed the competence to respond to dexamethasone by increased cystathionase activity, whereas the ability to respond to dibutyryl cyclic amp or glucagon became evident at a later developmental stage (during the last 2 days prior to term). simultaneous incubation with cycloheximide inhibited the stimulatory effect of these agents on foetal rat liver cystathionase activity in vitro. dexamethasone and glucagon w ... | 1975 | 167857 |
| comparison of interferon action in interferon resistant and sensitive l1210 cells. | translation inhibition, leu-trna aminoacylation and double-stranded rna and atp dependent phosphorylation were examined in interferon-treated and control cell-free lysates of leukaemic mouse l 1210 r and l 1210 s cells. no differences were observed between the respective interferon-treated and control cell-free extracts, except for the presence of an enhanced 67k dalton phosphoprotein fraction in interferon-treated l 1210 s cell-free extracts. in non-responding cell-free lysates, the lack of sti ... | 1978 | 212514 |
| the effect of a myelin apoprotein on lipid structure: a spin probe study. | spin probes, stable free radical derivatives of stearic acid and cholestanone, were used to observe the effects of the "folch-lees" protein isolated from the white matter of bovine brain on the organization and motion of lipid molecules. the incorporation of the organic solvent soluble form of this protein decreased the tendency of a variety of lipid molecules with zero, positive or negative net charges to arrange themselves close to the normal to the lipid bilayer. the aqueous form of the prote ... | 1975 | 167917 |
| transcription of endogenous c-type viruses in resting and proliferating tissues of balb/mo mice. | | 1979 | 228474 |
| [camera-cinematography of the heart (author's transl)]. | by "camera-cinematography" of the heart, we mean an isotope method which permits detailed observation of cardiac mechanics without the use of a catheter. all that is necessary is an intravenous injection of 10 to 15 mci 99mtc human serum albumen followed after ten minutes by a five to ten minute period of observation with a scintilation camera. at this time the isotope has become distributed in the blood. variations in the precordial impulses correspond with intra-cardiac changes of blood volume ... | 1975 | 130292 |
| [oculomotor reflex evoked by vibrassae stimulation in the cat]. | the oculomotor effects of vibrissae stimulation have been studied in the "encéphale isolé" non-anaesthetized cat. intracellular recording of lateral rectus motoneurones showed an excitatory projection via the ipsilateral infraorbital nerve to these motoneurones. the afferent fibers are type a alpha, recuited with a low threshold (0.2-0.5 ma) and convey information about vibrissae displacement. | 1979 | 120789 |