| the effect of a single dose of reserpine administered prior to incubation on the development of tyrosine hydroxylase activity in chick sympathetic ganglia. | a single dose of reserpine administered into the yolk sac of chicken eggs prior to incubation produces two distinct periods of significant increase in tyrosine hydroxylase (th) activity over controls. the first period is 21 days of incubation (55%) and the second is between day 14 and 30 after hatching (a.h.) (69%). cholineacetyltransferase (chac) and dopadecarboxylase (ddc) are not modified in the two periods of increased th activity. reserpine had no effect on cholinergic parasympathetic synap ... | 1977 | 14767 |
| gi pharmacology of polyethyleneimine ii: motor activity in anesthetized dogs. | the effects of orally and intravenously administered doses of polyethyleneimine were observed in 18 chloralose-urethan-anesthetized dogs. polyethyleneimine produced an initial augmentation of rhythmic segmenting gastric antral contractions, a copious flow of gastric mucus, increased segmenting and propulsive activities of the small and large intestines, and occasional micturition and defecation. the gastric corpus and fundic regions became relaxed and enlarged. these events were associated with ... | 1977 | 17723 |
| a comparison of in vitro and in vivo dopamine receptor antagonism produced by substituted benzamide drugs. | | 1978 | 22724 |
| myristic acid stimulation of bacterial bioluminescence in "aldehyde" mutants. | the involvement of long chain aldehyde in bacterial luminescence was known both from its being required for light emission in the in vitro reaction with pure luciferase and from its ability to stimulate luminescence in vivo in a certain class of dark "aldehyde" mutants. we have found that the luminescence of some (but not all) of such aldehyde mutants is also stimulated by long chain aliphatic fatty acids, with a marked specificity for myristic (tetradecanoic) acid. this stimulation has been dem ... | 1978 | 24214 |
| effect of low temperatures on the functional state of the membranes of the hepatic endoplasmic reticulum. | oxidation of fluorescent substrates--nadph and 4-dimethylamine chalcone (dmc) by microsomes from liver endoplasmic reticulum was studied after freezing and thawing of these cells organelles. slow freezing to -25 degrees or quick freezing to -196 degrees did not affect distinctly the rate of nadph oxidation after thawing, but oxidation of dmc by microsomes was decreased in both cases. freezing and subsequent thawing of microsomes impaired apparently the terminal sites of electron transfer and/or ... | 1978 | 30211 |
| the respiratory chain and proton electrochemical gradient in the alkalophile bacillus pasteurii [proceedings]. | | 1978 | 33860 |
| micro-ph and pco2 electrodes in the study of pancreatic electrolyte secretion [proceedings]. | | 1978 | 35177 |
| the development of the binocular depth cells in the secondary visual cortex of the lamb. | in most respects, the response properties of cells in the secondary visual cortex of the newborn lamb were indistinguishable from those in the adult. the cells were sharply selective to orientation; the orientation preferences were the same in each eye, and they varied systematically as the electrode penetrated the cortex. the receptive-field organization did not differ noticeably from that in adults, and complex, hypercomplex, and a few simple cells were all observed. the ocular dominance distr ... | 1979 | 38458 |
| flavin mononucleotide reductase of luminous bacteria. | nad(p)h: fmn oxidoreductase (flavin reductase) couples in vitro to bacterial luciferase. this reductase, which is also postulated to supply reduced flavin mononucleotide in vivo as a substrate for the bioluminescent reaction, has been partially purified and characterized from two species of luminous bacterial. from photobacterium fischeri the enzyme has a m. w. determined by sephadex gel filtration, of 43,000 and may have a subunit structure. the turnover number at 20 degrees c, based on a purit ... | 1975 | 47604 |
| value of routine serum-triiodothyronine estimation in diagnosis of thyrotoxicosis. | thyroid-stimulating hormone (t.s.h.), triiodothyronine (t3), and thyroxine (t4) concentrations were estimated on 432 blood specimens from patients with a provisional diagnosis of thyrotoxicosis. 59 patients had a raised serum t3 concentration with t.s.h. and t4 levels in the normal range. further information was obtained in 41 of these patients, and t3 toxicosis was diagnosed in 17 cases, thus providing a projected total of 24 patients with t3 toxicosis. in addition, there were 56 patients, with ... | 1975 | 53496 |
| delayed response of ankle jerk time changes in decreasing thyroid function in comparison with the serum cholesterol changes. | 1. serum cholesterol, pbi and ankle jerk time (ajt) were measured simultaneously in a group of not yet treated patients, where a relatively steady state of thyroid function was expected, and in a treated group, where change to lower thyroid function was supposed (thyrostatic drugs, near total thyroidectomy, radioablation of thyroid). 2. serum cholesterol correlated poorly with pbi (r = --0,4427), better correlation was achieved after logarithmic transformation of pbi values (r = --0,6839). 3. re ... | 1975 | 58781 |
| immunochemical properties of oligosaccharide-protein conjugates with klebsiella-k2 specificity. i. specificity and crossreactivity of anti-conjugate versus anti-bacterial antibodies. | | 1979 | 86152 |
| marketing in developing countries. | i fully support the views of mr. chetley of war on want on the marketing of infant foods in developing countries (oct. 6, p. 747). my experience of eight years medical work in west africa prompts me to broaden the debate. advertising and promotional practices used by many european and american pharmaceutical companies are in many instances directed primarily to the non-professional and often poorly educated general public and appear to be geared simply to achieve the maximum volume of sales. ... | 1979 | 91009 |
| cpc-pta section staining of acid glycans. | a cetylpyridinium chloride-phosphotungstic acid procedure suggested by kelényi and kiss (1976) for the staining of mast cell granules in ultrathin sections was slightly modified with regard to pretreatment, ph of incubation, and rinsing of sections. the method also proved suitable for the demonstration of various mucosubstances and of cartilage proteoglycan aggrebates. | 1979 | 91292 |
| the effect of d-penicillamine on the release of acid hydrolases from rat liver lysosomes induced by gamma-hexachlorcyclohexan. | | 1979 | 91374 |
| occurrence of beta 2-microglobulin in mammalian lymphocytes and erythrocytes. | cell-associated beta 2-microglobulin (beta 2m) has been studied by quantitative techniques in lymphocytes and erythrocytes of guinea pig, rabbit, rat and man. beta 2m was solubilized by sonication followed by treatment with acid, deoxycholate or thiocyanate, and then determined by radioimmunoassay. the average number of beta 2m molecules per lymphocyte, estimated after acidification, varied between 0.89 x 10(5) and 7.1 x 10(5). rat erythrocytes contained 3.0 x 10(3) molecules per cell, whereas n ... | 1979 | 91519 |
| characterization of a monoclonal anti-beta 2-microglobulin antibody and its use in the genetic and biochemical analysis of major histocompatibility antigens. | a monoclonal anti-beta 2-microglobulin (bbm.1 antibody) was produced by cell fusion between the mouse myeloma, p3-x63-ag8, and spleen cells from a balb/c mouse immunized with molt 4, a human t cell line. bbm.1 antibody was fully inhibited by soluble beta 2-microglobulin and purified hla-a, b antigens and reacted with human-mouse somatic cell hybrids only if they had chromosome 15 and expressed human beta 2-microglobulin. it was cytotoxic in complement-dependent lysis and of the igg class. bbm.1 ... | 1979 | 91522 |
| [response to catecholamines in rats deficient in essential fatty acids (proceedings)]. | | 1979 | 92240 |
| extra-axonal diffusion in the rabbit optic system: a caution in axonal transport studies. | the hazards of using optic nerve (as opposed to optic tract and more distal components of the optic system) to study axonal transport were highlighted by observing the fate of [14c]serine and [3h]glycerol injected into the rabbit eye. despite prior blockage of axonal transport with colchicine, appreciable radioactivity rapidly appeared in the optic nerve adjacent to the injected eye. radioactivity decreased exponentially along the entire optic chiasm. counts were distributed among the lipid, pro ... | 1979 | 92351 |
| [a comparison of the immunosuppressive effect of normal and purified alpha-globulin fraction of human plasma]. | | 1979 | 92373 |
| black and white human skin differences. | this review of black and white human skin differences emphasizes the alleged importance of factors other than the obvious, i.e., skin color. physicochemical differences and differences in susceptibility to irritants and allergens suggest a more resistant black than white skin. differences appear to exist in the frequency of which several skin diseases occur among blacks and whites. a striking feature in this literature is the disagreement between authors. common for much of this information is d ... | 1979 | 92483 |
| cytotoxic enteropathogenic escherichia coli. | | 1979 | 92636 |
| enhancement of beta 2-microglobulin formation induced by phytohemagglutinin and mercuric ion in cultured human leucocytes. | | 1979 | 92991 |
| [effect of test conditions on the results of the radial immunodiffusion reaction with viral antigens]. | | 1979 | 93161 |
| electron spin resonance studies on phaeomelanins. | esr spectra of synthetic melanins formed from dopa and from 5-s-cysteinyldopa and of melanins isolated from human melanomas were studied. alkali-soluble melanin synthesized from cysteinyldopa showed a signal similar to that of insoluble melanin synthesized from dopa, but also a simple fine structure. trichochromes c and f synthesized from 5-s-cysteinyldopa had a broader signal than dopamelanin, and in addition a hyperfine structure that could be explained by the presence of manganous ions. an in ... | 1979 | 93370 |
| the interaction of lanthanides with isolated sarcoplasmic reticulum vesicles from rabbit skeletal muscle. | the interaction of lanthanides with isolated sarcoplasmic reticulum (sr) vesicles from rabbit skeletal muscle and the effects of lanthanides on 45ca2+ uptake by the vesicles were studied. 153gd3+ was taken up by the vesicles in the absence of atp and oxalate in a time-dependent manner, reaching a maximum total accumulation of 380 nmol 153gd3+/mg protein after 20 min with 200 microm 153gd3+. this 153gd3+ accumulation was not washed out by 1 mm egta. the addition of atp induced the release of 87% ... | 1979 | 93439 |
| sequence of the haem-binding region of cytochrome c-556 from agrobacterium tumefaciens, strain b2a [proceedings]. | | 1979 | 93467 |
| [effects of tween stabilization on the sensitivity and specificity of mycobacterial purified protein derivatives]. | | 1979 | 93498 |
| role of the pituitary gland in experimental hormonal induction and prevention of benign prostatic hyperplasia in the dog. | the antiandrogen, cyproterone acetate (cpa), prevents development of prostatic hyperplasia, induced in castrated dogs by a 6 month-treatment with 5 alpha-androstane-3 alpha, 17 beta-diol (a)alone or in combination with 17 beta-oestradiol (e2). the immunoperoxidase technique was used to study functional cell types in the pars distalis of the pituitary gland and to detect growth hormone (gh) and prolactin (prl) target sites in the prostate gland. homologous radioimmunoassays for estimation of seru ... | 1979 | 93515 |
| a simple method for staining semi-thick tissue sections to demonstrate fungal elements. | a simple method of staining epon embedded semi-thick sections with schiff-reagent is described. this technique allows fungal elements in tissue to be readily observed. the combination of schiff-reagent with a methylene blue counterstain for demonstrating fungal elements and tissue structures is also described. | 1979 | 93702 |
| rna modulating specific and nonspecific immune responses. | | 1979 | 93861 |
| photolysis of mast cells in presence of protoporphyrin. | the effects of ultraviolet and visible irradiation in presence of protoporhyrin upon mast cells were investigated. rat peritoneal mast cells were suspended in a medium containing varying concentrations of protoporphyrin and were irradiated using a mercury vapor lamp. the release of histamine is related to both the concentrations of protoporphyrin and the period of irradiation. comparatively negligible amounts of histamine were released when the cells were irradiated in absence of protophyrin or ... | 1979 | 94207 |
| a critical re-evaluation of the anisotropic index used in polarization microscopy: a study on epiphyseal cartilage. | topo-optical reactions specific for collagen and glycosaminoglycans were performed on epiphyseal cartilage plates which differed in age, in chemical composition, and in structure. retardation values were measured with the polarization microscope and anisotropic index values were calculated after each reaction. it was found that the anisotropic index proposed earlier for quantitative evaluation of topo-optical reactions did not refer either to the submicroscopic orientation pattern or to the quan ... | 1979 | 94227 |
| developments in the control tests to improving the quality of the human placental gammaglobulin. | | 1978 | 94255 |
| neural control of glycogen content and its diurnal rhythm in mouse pineal cell. | in adult male dd mice, possible mechanisms regulating the glycogen content in the pineal cell were investigated by a semiquantitative histochemical method, with particular reference to the role of the sympathetic innervation. reserpine, superior cervical ganglionectomy (scgx), or decentralization of the ganglia (dc), as well as continuous light, prevented the nocturnal decrease in the glycogen content, causing a marked increase, and caused a gradual decrease in the size of the pineal cell. in th ... | 1977 | 18016 |
| relationships among raffinose plasmids determined by the immunochemical cross-reaction of their alpha-galactosidases. | plasmid-encoded alpha-galactosidase served as a marker enzyme for the recognition and comparison of raffinose (raf) plasmids present in strains of escherichia coli. immunochemical relationships were established among raf plasmids of 39 independent isolates from man and domestic animals (from three continents) by using antiserum against alpha-galactosidase. immunodiffusion revealed three serological subclasses of alpha-galactosidase, which are correlated with the biological and geographical origi ... | 1979 | 94343 |
| somatic cell genetics of human interferon production in human-rodent cell hybrids. | forty-two primary human-mouse cell hybrids, derived in two separate experiments, were treated with newcastle disease virus (ndv): eight hybrids were found to produce human interferon and this was shown in every case to be predominantly of the fibroblast type. an extensive analysis was made in terms of karyotype and marker enzymes on all the eight hybrids producing interferon and also on five hybrids which did not produce interferon, five randomly selected hybrids and eleven subclones resistant t ... | 1979 | 94346 |
| reversal of serotonin vasodilatation in the dog external carotid bed by sympathetic denervation. | in view of the conflicting reports of both constrictor and dilator effects of serotonin on the external carotid vascular bed of dogs, the influence of intraarterial infusions of the amine on blood flow through this territory was assessed by electromagnetic flowmeter techniques. in anesthetized intact dogs, serotonin produced dose-related increases in flow. these vasodilator responses were markedly diminished after ipsilateral vagotomy and were followed by delayed vasoconstriction, which then bec ... | 1979 | 94376 |
| comparison between the acute hemodynamic effects and brain penetration of atenolol and metoprolol. | atenolol and metoprolol are beta 1-selective adrenergic receptor blockers, devoid of local anesthetic and intrinsic sympathomimetic properties. their antihypertensive and hypotensive activities are equivalent. they differ with respect to their lipophilic character, as is apparent from their octanol/buffer (ph, 7.4 at 37 degrees c) partition coefficients: metoprolol, 1.084; atenolol, 0.012. we compared the two agents with regard to their acute hemodynamic effects and degree of penetration into th ... | 1979 | 94385 |
| influence of substance p on mesenteric hemodynamics in the pig. | | 1979 | 94532 |
| prazosin first-pass metabolism and hepatic extraction in the dog. | the short half-life, low plasma concentrations, and extensive biotransformation of prazosin suggest that it might be subject to extensive first-pass metabolism. bioavailability, disposition, and hepatic extraction were studied in the dog. in conscious dogs whole blood prazosin concentrations were measured after oral and intravenous administration of the drug. anesthetized dogs were used to measure prazosin concentrations in arterial and hepatic venous blood samples drawn simultaneously. the bioa ... | 1979 | 94630 |
| chronic metabolic effects of ammonia in mouse brain. | chronic ammonia toxicity in experimental mice was induced by exposing them for 2 and 5 days to 5 % (v/v) ammonia solution. the enzymes concerned with glutamate metabolism (aspartate-, alanine- and tyrosine aminotransferases, glutamate dehydrogenase and glutamine synthetase) and (na+ + k+)-atpase were estimated in the three regions of brain (cerebellum, cerebral cortex and brain stem) and in liver. glutamate, aspartate, alanine, glutamine and gaba, rna and protein were also estimated in the three ... | 1979 | 94819 |
| mechanism of binding of mouse interferon to controlled pore glass. | many proteins bind to controlled pore glass; they are either acid elutable or alkali elutable. mouse interferon is an acid-elutable protein. since poly(l-lysine) and, to some extent, poly(l-arginine) are also eluted from controlled pore glass under acidic conditions, one may postulate that mouse interferon binds to controlled pore glass via some of the protein's epsilon-amino groups (of lysine) and/or guanidinium groups (of arginine) and the beads' silanol (hydroxyl groups). the necessity of lys ... | 1979 | 94835 |
| application of uracil-bonded silica gel to the separation of adenine and its derivatives, and to poly(a)-containing rna. | | 1979 | 94919 |
| a silver carbonate method for cell counts of neurons and glial elements on paraffin embedded brain tissue. | a modification of the del rio-hortega method for the demonstration of central nervous system elements is presented. this silver impregnation technique is particularly useful for the classification of cell types for quantitative differential cell counts. formalin fixed paraffin sections are immersed in formol-ammonium bromide for 1 1/2 hours; this solution is an excellent mordant for various silver nitrate stains. the samples are stained for 20 to 60 minutes in a silver carbonate solution (25 ml ... | 1979 | 94949 |
| actions of quinacrine on rna and casein syntheses in mouse mammary gland explants. | quinacrine at concentrations of 0.025 mm and greater significantly reduced or abolished the prolactin stimulation of rna synthesis in mouse mammary gland explants. at concentrations of 0.01 mm or greater, the stimulatory action of prolactin on [3h]-leucine incorporation into a casein-rich protein fraction was also reduced or abolished. the possible relationship of these actions of quinacrine to its inhibition of phospholipase a2 and/or prostaglandin biosynthesis is discussed. | 1979 | 95126 |
| cytogenetic analysis of double satellites on marker chromosome no. 14. | | 1979 | 95131 |
| characterization of stem cells and progenitors of hemopoiesis by cell sorting. | cell sorting has been used as a method for characterizing hemopoietic stem cells and progenitors. fluorescent antibody-surface labels and changes in fluorescence polarization induced by in vitro stimulation with potential hemopoietic regulators were used. as detected by significant enrichment of cfu-s (pluripotent stem cells) in fluorescence-activated cell sorting, some cfu-s bear 'unique antigens' recognized by rabbit anti-human brain sera, human anti-human sperm sera, and 129 anti-f9 serum, bu ... | 1979 | 95516 |
| association of diamine oxidase and ornithine decarboxylase with maturing cells in rapidly proliferating epithelium. | diamine oxidase and ornithine decarboxylase activities are shown to have a parallel distribution across rat small intestine mucosa; levels of both enzyme activities are sharply higher in mature cells in the villus tip region than in proliferating cells in the crypt areas. histidine decarboxylase levels were not measurable in the same cell preparations and aromatic-l-amino-acid decarboxylase activity was distributed in an opposite pattern to diamine oxidase and ornithine decarboxylase. the result ... | 1978 | 96870 |
| measurement of gamma-aminobutyric acid (gaba) in blood. | | 1978 | 97484 |
| biochemical changes in guinea pig lungs due to amosite asbestos. | | 1978 | 98326 |
| changes in composition of tears of malnourished children. | | 1978 | 98738 |
| experimental spinal cord trauma, ii: blood flow, tissue oxygen, evoked potentials in both paretic and plegic monkeys. | graded clinical motor deficits were produced in a series of rhesus monkeys subjected to experimental spinal cord trauma from a variety of impact loads. an argon washout technique was used to measure spinal cord blood flow; tissue oxygen carbon dioxide, and somatosensory evoked potentials (seps) were also monitored. each animal received a clinical grade and, after a week of study, the spinal cords were removed for histopathological grading. blood flow in paraplegic animals was significantly decre ... | 1978 | 98856 |
| age-associated changes in the blood picture of the goat. | | 1978 | 98936 |
| improved safety of splenoportography by plugging of the needle tract. | splenoportography, a useful preoperative diagnostic procedure in patients with portal hypertension, has been largely discontinued because of the risk of hemorrhage. we have used both ivalon and gelfoam in particle and plug form to plug the needle tract after splenoportography. initial studies were conducted on six dogs. plugging of the needle tract by injection of suspensions of small gelfoam or ivalon particles resulted in intravasation of these particles into the splenic vein. this was demonst ... | 1978 | 98987 |
| fibrinogen turnover in pregnant rabbits during the first and last thirds of gestation. | although thrombin-mediated fibrinogen derivatives have been observed in normal pregnancy, an increased turnover of fibrinogen has been suspected but has not yet been demonstrated. fibrinogen turnover was studied in 14 pregnant and 10 nonpregnant female rabbits by use of purified rabbit 125i-labeled fibrinogen. in the last third of gestation the half life of fibrinogen was shortened by 45% and the fractional catabolic rate increased by 44% in comparison to the values for the first third of gestat ... | 1978 | 99036 |
| fluorometric assay for measuring biological half-life of coralyne sulfoacetate in dogs and monkeys. | a spectrophotofluorometric assay for coralyne sulfoacetate was developed. caralyne was extracted from serum samples with n-butyl alcohol, and the drug concentrations were determined fluorometrically at 475 nm when the extract was excited at 325 nm. a biphasic serum decay curve for coralyne was observed for both dogs and monkeys. the biological half-lives for the two phases were 20 and 196 min in dogs and 15 and 142 min in monkeys. | 1978 | 99510 |
| ultrastructural observations on the maturation and secretion of granules in atrial myocardium. | | 1978 | 99521 |
| [serotyping of pseudomonas aeruginosa]. | | 1978 | 101427 |
| murine macrophage-lymphocyte interactions: scanning electron microscopic study. | light and scanning electron microscopic observations revealed murine macrophage-lymphocyte interactions involving the initial contact of peritoneal, spleen, or thymus lymphocytes with peritoneal macrophage processes or microprocesses followed by clustering of lymphocytes over the central nuclear area of the macrophages. lymphocyte-lymphocyte clustering was not observed in the absence of macrophages. attachment and subsequent clustering appeared not to require the presence of serum or antigen; th ... | 1978 | 101458 |
| dominant constitutive mutations in malt, the positive regulator gene of the maltose regulon in escherichia coli. | | 1978 | 101676 |
| short-term memory in the rhesus monkey: effects of dopamine blockade via acute haloperidol administration. | the effects of dopaminergic blockade on recent or short-term memory (stm) were evaluated in test-sophisticated rhesus monkeys. each monkey was tested under several doses of the antidopaminergic haloperidol (0.006 to 0.05 mg/kg), in an automated, delayed-response procedure. the same procedure and test apparatus had previously been used to demonstrate profound stm impairments in aged rhesus monkeys and strikingly similar deficits in young monkeys given the anticholinergic scopolamine. the results ... | 1978 | 101990 |
| [the effect of prolonged irradiation and of certain radioprotective agents on glycosaminoglycans in the rat]. | | 1978 | 101997 |
| homovanillic acid in human csf: comparison of fluorimetry and gas chromatography-mass spectrometry. | | 1978 | 103678 |
| [studies on staphylococcal enterotoxin b. 1. quantitative assay by capillary tube single diffusion test (author's transl)]. | a method for rapidly identifying and quantitating small amount of staphylococcal enterotoxin b was developed on capillary tube single diffusion test. the high sensitivity of method has the advantages to save antiserum and incubation period. some factors such as concentration of antigen and antiserum, incubation temperature, buffer systems, and position of capillary tube all might affect the test accuracy. if all those affecting factors were concerned, the toxin would probably be standardized. th ... | 1978 | 103693 |
| [detection of occult viral pancreatic necrosis infection and viral hemorrhagic septicemia in rainbow trout (s. gaerdneri) in hatcheries with consideration of structural conditions]. | | 1978 | 103702 |
| identification of a prothrombin derivative in human urine. | | 1978 | 105420 |
| maternal separation vs removal from group companions in rhesus monkeys. | | 1979 | 106065 |
| disinfection of nitrous oxide inhalation equipment. | cross-infection by contaminated equipment is a potential hazard associated with conscious sedation with nitrous oxide and oxygen . nosocomial infections have occasionally been linked wih the use of unsterile inhalation devices; microbial contamination of sterile nasal hoods routinely occurs during administration of nitrous oxide; and in vitro experiments indicate that subsequent use of contaminated nasal masks may lead to aspiration of microorganisms. although the incidence of respiratory diseas ... | 1979 | 106079 |
| [antibody induced phase variation in pseudomonas aeruginosa (author's transl)]. | to extend the flagella specific h antigenic schema of p. aeruginosa (ansorg, 1978), investigations are carried out to reveal phase variation in this species as in salmonella or arizona. with conventional methods, i.e. examination of single colonies after plating the cultures on standard nutrient agar or the phase reversal techniques of craigie (1931) and gard (1938) by adding homologous anti-oh-serum of different amounts in semisolid agar medium, no change of the flagellar antigens of various p. ... | 1978 | 106580 |
| minimum blood vessel diameter measured by magnification angiography. | visibility of small blood vessels was improved by magnification angiography of biologic specimens. blood vessel diameter was determined for increasing magnifications by various screen-film combination. significantly smaller vessels were recognized with the magnification technique in all screen combinations. noisy screen-film combinations with better square wave transfer functions did not allow visualization of blood vessels as small as those screen-film combinations with poorer square wave trans ... | 1979 | 106650 |
| hospital isolates of serratia marcescens transferring ampicillin, carbenicillin, and gentamicin resistance to other gram-negative bacteria including pseudomonas aeruginosa. | thirteen independent isolates of serratia marcescens associated with nosocomial urinary tract infections were obtained from the clinical microbiology laboratory at hines veterans administration hospital. the isolates were resistant to at least ampicillin, carbenicillin, gentamicin, and tobramycin. they could be divided into two groups on the basis of their antibiotypes. group i (9 strains) showed resistance to 13 antibiotics, including 3 beta-lactams, 6 aminoglycosides, tetracycline, sulfonamide ... | 1979 | 106772 |
| [detection of healthy carriers of neisseria meningitidis in a sample of the population of the city of messina]. | | 1977 | 106778 |
| the cellulolytic enzymes of botryodiplodia theobromae pat. separation and characterization of cellulases and beta-glucosidases. | 1. filtrates from cultures of different ages of botryodiplodia theobromae pat. were fractionated by gel filtration, ion-exchange chromatography and polyacrylamide-gel electrophoresis. 2. five cellulases (c1, c2, c3, c4 and c5) were found, and their molecular weights, estimated by gel filtration, were 46000-48000 (c1), 30000-35000 (c2), 15000-18000 (c3), 10000-11000 (c4) and 4800-5500 (c5). 3. cellulase c5 was absent from old culture filtrates. 4. cellulase c1 had little or no activity on cm-cell ... | 1979 | 106849 |
| carboxypeptidase of streptomyces griseus. implications of its characteristics. | | 1979 | 106886 |
| metabolism of diethylstilbestrol: identification of a catechol derived from dienestrol. | the enzymatic oxidation of e-3,4-bis-(p-hydroxyphenyl)-hex-3-ene (diethylstilbestrol) by either mushroom tyrosinase or rat liver microsomes in the presence of nadph and air yields a catechol. upon further oxidation of both compounds with periodate and condensation of the resulting o-quinones with o-phenylenediamine, phenazines are produced. the phenazines derived from the products of both the plant and animal enzyme systems are identical to the product obtained by oxidation of diethylstilbestrol ... | 1978 | 106901 |
| sensitive neutralization test for rubella antibody. | a modified rubella virus plaque neutralization test for measuring rubella antibody was developed based on the potentiation of the virus-antibody complex by heterologous anti-immunoglobulin. the test is highly sensitive, yielding titers on the average 50 to 100 times higher than the haemagglutination inhibition test or the conventional plaque neutralization test. the sensitivity of this enhanced neutralization test is somewhat limited by the existence of a prozone phenomenon which precludes testi ... | 1979 | 107192 |
| prolongation of islet allograft survival following in vitro culture (24 degrees c) and a single injection of als. | isolated rat islets remain morphologically and functionally intact during a 7-day period of in vitro culture at 24 degrees c. in vitro culture of islets at 24 degrees c for 7 days prior to transplantation, in conjunction with a single injection of antiserum to lymphocytes into the diabetic recipient, results in islet allograft survival of 100 days when the islets are transplanted across a major histocompatibility barrier. | 1979 | 107588 |
| schistosomiasis japonica in barrio san antonio, basey, samar in the philippines: ii. quantitative fecal examination and circumoval precipitin tests. | an improved quantitative stool examination technique (mfct) and two variations in the performance of the circumoval precipitin test, one using whole serum (scopt) and the other employing the eluate from finger prick blood dried on filter paper (fpcopt), were evaluated in a field study to detect infection with s. japonicum among residents of an endemic barrio in samar. the sensitivity of scopt was above 90%, that of mfct was between 80 to 90%, while that of fpcopt was only about 50%. intensity of ... | 1978 | 107595 |
| pituitary-thyroid function in spironolactone treated hypertensive women. | four weeks high dose spironolactone treatment (aldactone searle, 100 mg q. i. d.) significantly enhanced the tsh (delta max. 8.5 +/- 4.1 vs. 4.6 +/- 3.1 microunits/ml, p less than 0.05) and t3 (delta max. 32 +/- 27 vs. 11 +/- 16 ng/100 ml, p less than 0.05) responses to an intravenous trh/lh-rh bolus injection in 6 eumenorrhoeic euthyroid hypertensive women, without affecting basal serum tsh, t3 or t4 levels or the basal and stimulated lh, fsh and prolactin values (p greater than 0.10). the mean ... | 1979 | 107696 |
| experimental transmission of wuchereria bancrofti to monkeys. | infective larvae of wuchereria bancrofti from laboratory-raised culex pipiens fatigans and aedes togoi mosquitoes fed on human volunteers in jakarta, indonesia (j strain) and kinmen island, china (k strain) were introduced into taiwan monkeys (macaca cyclopis) by subcutaneous inoculation, by foot puncture, or by permitting infected mosquitoes to feed weekly on the monkeys. some animals were splenectomized and others were treated with varying regimens of immunosuppressants. necropsy was done on m ... | 1979 | 107818 |
| stability and viability of neisseria gonorrhoeae in various solutions and buffers. | the stability and viability of neisseria gonorrhoeae wp (t4) was tested in a variety of buffers and solutions, many of which are commonly used in gonococcal research. each solution was tested at room temperature for its ability to maintain stability and viability of gonococci in concentrated suspensions and to maintain viability of gonococci in dilute suspensions. the 14 buffers and solutions tested could be divided into four groups based upon these criteria. only a few solutions satisfied all t ... | 1979 | 107855 |
| slow infections with unconventional viruses. | | 1978 | 108233 |
| effect of neonatal hypothyroidism and delayed l-triiodothyronine treatment on behavioural activity and norepinephrine and dopamine biosynthetic systems in discrete regions of rat brain. | | 1979 | 111295 |
| cost-benefit studies of vaccinations in finland. | the benefits of vaccination are, in general, recognized. for some diseases these benefits are obvious. when starting or evaluating new vaccination programmes, a more critical approach is needed. before starting vaccination against measles and rubella in finland a cost-benefit study was performed. according to those studies the net benefits of each vaccination would be ca. 100 million finnish marks in 25-30 years. those benefits not measurable in money value of human life, decrease of suffering, ... | 1979 | 118069 |
| barbiturates in neurosurgery. | | 1979 | 120795 |
| [study of soluble proteins from human amniotic fluid by fraction chromatography (author's transl]. | the nature and origin of soluble proteins from human amniotic fluid have been investigated by gel filtration chromatography on sepharose 6b and ion-exchange chromatography on ecteola-cellulose. each fraction has been studied by immunoelectrophoresis. specific antisera against serum proteins, amniotic fluid proteins, fetal proteins and salivary proteins have been used. these various antisera showed that the amniotic fluid contains maternal proteins, but also more specific proteins from fetal orig ... | 1975 | 123833 |
| human polymorphonuclear leukocyte elastase and cathepsin g mediate the degradation of lapine articular cartilage proteoglycan. | | 1975 | 126033 |
| kinetic studies on inhibition of dog heart na+,k+-dependent atpase by k+,mg2+-aspartate: comparison with ouabain. | both k+,mg+-dependent d,l-aspartate and d,l-aspartic acid are noncompetitive inhibitors of dog heart na+,k+-atpase acting at the overlapping site as does ouabain. for the na+,k+-atpase, the salient effects of k+,mg+-d,l-aspartate and/or d,l-asartic acid were: 1) decrease in maximal velocity (v) for atp as substrate with unchanged km; 2) for sodium as an allosteric modifier of na+,k+-atpase activity, a decrease in v without any alteration in n as measure of cooperativity between activating sites; ... | 1975 | 127359 |
| a comparison of drug-induced rotation in rats lesioned in the medial forebrain bundle with 5,6-dihydroxytryptamine or 6-hydroxydopamine. | drug-induced rotational behaviour was studied in two groups of rats with differing chemical lesion of the right medial forebrain bundle (mfb). 6-hydroxydopamine (6-oh-da), 3.5 mug, injected in one group, induced a marked lowering of dopamine (da) and noradrenaline (na) in the right hemiforebrain. 5,6-dihydroxytryptamine (5,6-ht), 10 mug, injected in a second group, produced a profound and long-lasting depletion of 5-hydroxytryptamine (5-ht) and da, but not of na. rotational behaviour induced in ... | 1975 | 127559 |
| [influence of long-term swimming training on the structure and enzyme activity of myosin in the rat myocardium (author's transl)]. | intermittent hemodynamic loading of the rat myocardium due to swimming training for several weeks leads to a significant increase in the specific atpase activity of myosin. this enzymatic alteration of the myosin molecule is accompanied by changes in the stoichiometry of its light chains which are of great significance for the atpase activity. the maximum shortening velocity of the unloaded myocardium (vmax), estimated on the basis of afterloaded contractions, shows a slight increase as a result ... | 1975 | 127740 |
| [synchronous electric activity with inspiration in the vastus lateralis muscle of the anesthesied dog breathing spontaneously]. | in the dog, under chloralose or pentobarbitone anesthesia and breathing spontaneously, a muscular electrical activity of low voltage synchronous with respiration was observed in m. vastus lateralis. the mean maximum amplitude of this activity is inversely linked with respiratory rate. when the respiratory frequency is equal or exceeds 25 cycles per minute this activity disappears. such a phenomenon seems to be related to the activity of the respiratory centre. | 1976 | 134813 |
| [on the problem of atypical dysentery bacilli (author's transl)]. | | 1976 | 135237 |
| [evolution of enterobiasis demonstrated by the action of active and passive detection with a (modified) nih method in oradea]. | the incidence of enterobiosis in the infantile population of oradea was followed up by a modified nih laboratory method. active detection revealed an incidence of a latent state of enterobiosis of 21.9% in 1970, which fell to 3.9% in 1973. by passive detection, enterobiosis was found to decrease from 22.6% in 1970 to 16.1% in 1973, owing to the efficiency of the investigations and treatment applied. | 1976 | 135333 |
| effect of beta-phenylethylamine and d-amphetamine on electrical self-stimulation of brain. | beta-phenylethylamine (pea) has been viewed as amphetamine-like in its effects on behavior. support for this putative similarity of action has been derived primarily from observations that both of these structually related compounds increase locomotor activity in a dose-related manner and at higher doses evoke stereotypies. since d-amphetamine (d-a) produces a dose-related increase in the rate of bar pressing for electrical stimulation of the medial forebrain bundle, the effect of pea on this be ... | 1976 | 139616 |
| [contribution to the embryotoxic effect of chloramphenicol in the animal experiment]. | | 1977 | 141839 |
| in vitro reactivity in allograft tolerance: persistence of mixed leukocyte culture reactivity in highly tolerant rats. | mixed leukocyte culture reactivity was studied in adult w/fu rats judged to be highly tolerant after the inoculation of (w/fu x bn)f1 hybrid spleen and bone marrow cells at birth. reactivity was observed in a majority of tolerant donors tested and documented by quantitative dose-response and kinetic studies. allograft tolerance cannot be explained by a complete lack of specific immune reactivity to tolerated alloantigens. | 1977 | 142793 |
| biochemical study of testosterone in skin: in vivo and in vitro metabolism of testosterone in rat skin. | | 1977 | 143191 |
| myelin deficiency in experimental phenylketonuria: contribution of the aromatic acid metabolites of phenylalanine. | retarded body and brain growth and a deficit of myelin in the cerebral hemispheres and the cerebellum were observed in an animal model of phenylketonuria, the p-chlorophenylalanine and l-phenylalanine treated preweanling rat. these manifestations of phenylketonuria were reproduced in rats treated with phenylacetate in amounts approximating those likely to be produced in phenylketonuria. young rats treated with equivalent amounts of other metabolites of phenylalanine, namely, phenylpyruvate, phen ... | 1978 | 151497 |
| interaction between the mechanical properties of the respiratory system and drive in the control of breathing of anesthetized man. | | 1978 | 151498 |