| purification and some properties of a neutral muscle pyrophosphatase. | in the water-soluble fraction of rabbit skeletal muscle, at least two types of inorganic pyro phosphatase (ppase) are distinguishable on ion exchange column chromatography. one of them, pyrophosphatase-a (ppase-a), was isolated in an electrophoretically homogeneous form. this enzyme catalyzed the hydrolysis of ppi but not that of other phosphate esters. only mg2+ was required for activity and stability. other cations such as ca2+, co2+, mn2+, and zn2+ had no activating effect. the activity of th ... | 1978 | 25268 |
| [use of the phases of growth of the causative agents of plaque and pseudotuberculosis for differentiation of these microorganisms]. | | 1976 | 56492 |
| vidarabine monophosphate in viral encephalitis. | | 1979 | 86765 |
| in vitro benzo[a]pyrene metabolism from lindane-treated rat liver: effect of oral and acute administration, and comparison with phenobarbital and methylcholanthrene pretreatment. | | 1979 | 87034 |
| moloney virus-induced cell surface antigens and histocompatibility antigens are located on distinct molecules. | | 1979 | 87439 |
| [determination of serum ammonia and urea in far eastern scarlatina-like fever as an auxiliary method of early diagnosis]. | | 1979 | 89255 |
| prolonged survival of corneal allografts in rabbits treated with cyclosporin a. | | 1979 | 90771 |
| [effect of test conditions on the results of the radial immunodiffusion reaction with viral antigens]. | | 1979 | 93161 |
| effect of azacytidine on simian virus 40 nucleoprotein complexes. | simian virus 40 nucleoprotein complexes synthesized in the presence of 5-azacytidine showed small differences in sedimentation rate on neutral sucrose and buoyant density in metrizamide and cesium chloride. simian virus 40 deoxyribonucleic acid (dna) i, isolated from the nucleoprotein complexes of drug-treated cultures, was found to band at a higher buoyant density and therefore had a decreased ability to bind ethidium bromide. the data indicated that these molecules were deficient in superhelic ... | 1979 | 93427 |
| effects of intrathecal and intracerebroventricular injections of substance p on nociception in the rat and mouse [proceedings]. | | 1979 | 93501 |
| adult human skin maintained in organ culture: i. the ultrastructure of the acellular compartment of connective tissue. | collagenolytic enzymes are produced by cultured skin explants. during cultivation the acellular compartment of the dermal connective tissues is digested away. the ultrastructure of the connective tissue resorption has been studied in human skin maintained in organ culture for 2--10 weeks. the connective tissue changes are: (1) collagen fibrils with normal axial periodicity but decreasing diameters. on cross sections these fibrils have irregular outlines, while the longitudinal sections show fibr ... | 1979 | 93361 |
| delayed hypersensitivity to staphylococcus aureus in mice: in vivo responses to isolated staphylococcal antigens. | the development of delayed hypersensitivity (dh) to staphylococcus aureus in swiss mice was evaluated by the footpad (fp) assay. in order to determine which component of the bacteria was responsible for the in vivo immune reactivity, purified staphylococcal cell wall, cell membrane, protein a, lipoteichoic acid, teichoic acid, as well as lipid-free membrane proteins were isolated. the immune responses of mice receiving one to eight s. aureus injections indicated that the first dh peak, following ... | 1979 | 93087 |
| [physicochemical properties of neurospecific basic protein (scp) of the spinal cord]. | basic protein (scp) known as antiencephalytogenic was isolated from the bull spinal cord and spinal roots. the protein is purified to a molecular homogeneous state, some of its physicochemical properties are studied. molecular homogeneity of the protein is established by the method of disk electrophoresis in 15% polyacrylamide gel with sodium dodecyl sulphate present and by analytic ultracentrifugation. during electrophoresis in 15% polyacrylamide gel at ph 4.0 the protein movement occurs only i ... | 1979 | 92837 |
| nonspecific light loss and intrinsic dna variation problems associated with feulgen dna cytophotometry. | nonspecific light loss by the cell-wall-plus-cytoplasm (cwc) can cause a 50% increase in feulgen absorption units in peanut root-tip nuclei as determined by scanning at 450 nm, whereas this phenomenon is not evident with chicken erythrocytes. a two wavelength scanning method of subtracting nonspecific 450 nm absorption from 550 nm feulgen absorption values eliminated the nonspecific light loss in cwc, however, the two wavelength scanning method is time consuming and somewhat impractical with a r ... | 1979 | 92496 |
| viability assessment by dye exclusion. a fluorescent method for fungal cells. | a new fluorescent staining technique for fungi utilizes the differential affinity of dead cells for rhodamine b. a mounting medium has been devised that includes the dye. this medium allows direct processing of cells from a broth and provides optimal conditions for fluorescence intensity. comparison with the standard methylene blue exclusion test as applied to the candida albicans yeast phase indicates similar specificity. various pseudohyphae and several fungi also exhibited selective uptake of ... | 1979 | 92216 |
| [lectin binding sites of the human pituitary adenoma cells as revealed by the ferritin- and horseradish peroxidase-labeled techniques (author's transl)]. | | 1979 | 94659 |
| connectivity of the auditory forebrain nuclei in the guinea fowl (numida meleagris). | injection of tritiated leucine and proline into the nucleus ovoidalis of the guinea fowl (numida meleagris) produces terminal labeling in the palaeostriatum and in three adjacent zones (field l1-l3) of the auditory neostriatum (an). l2, situated between l1 and l3, receives the main input and corresponds to the former field l of rose. these neuroanatomically defined zones of the auditory neostriatum are also characterized by differing properties of their neurons. injection of radioactive material ... | 1979 | 91442 |
| cell differentiation in human gastric gland as revealed by nuclear binding of tritiated actinomycin. | the nuclear binding of h3 actinomycin, which is closely linked to the differentiation phenomenon, was studied in human normal gastric mucosa. actinomycin binding decreases in cells which differentiate and becomes very low in fully differentiated cells. in the gastric pits, there is a decreasing gradient of labelling from the deeper stem cells to the well-differentiated superficial cells. this indicates that migration and renewal of the surface epithelium occurs following a 'pipe-line' system. al ... | 1979 | 90638 |
| preliminary studies on nasal decongestant activity from the seed of the shea butter tree, butyrospermum parkii. | 1 the seed of butyrospermum parkii yields shea butter which according to local traditional healers relieves inflammation of the nostrils. 2 since there is as yet no absolutely satisfactory nasal decongestant in clinical use, it was decided to investigate the effects of shea butter in nasal congestion. the substance was prepared in the laboratory. 3 the human subjects used were those suffering from rhinitis with moderate to severe nasal congestion. they were divided into the test group which rece ... | 1979 | 89854 |
| structural studies on the immunodominant group of lipid a from lipopolysaccharide of yersinia pseudotuberculosis. | lipid a isolated from lipopolysaccharide of yersinia pseudotuberculosis was used for immunization of rabbits to afford antisera to lipid a with titers of 1:640 in the passive hemolysis test. exhaustion of immune serume with sheep erythrocytes decreased antibody titers up to 1:160. authentic samples of 2-(dl-3-hydroxytetradecanoyl)amino-2-deoxy-d-glucose 6-phosphate, 2-tetradecanoylamino-2-deoxy-d-glucose 6-phosphate and 2-acetamido-2-deoxy-d-glucose 6-phosphate have been synthesized in order to ... | 1979 | 89032 |
| [spontaneous rosette forming, fc and complement receptor bearing lymphocytes in pediatric diseases]. | investigations with lymphocyte subpopulations were made in 51 children aged from 1-14 years with infections of the upper airways, with acute leukaemias, and other malignant diseases. t-lymphocytes were registered by means of the spontaneous rosette test. the attempt of proving b-lymphocytes was made by means of an eac test with human erythrocytes, anti-d-immunoglobulins and human complement. the results were compared with those obtained by an eac test with sheep erythrocytes, sheep haemolysin an ... | 1979 | 88386 |
| ultrastructure of peptidergic neurosecretory axons in the developing neural lobe of the rat. | | 1978 | 86479 |
| [antitumor activity and preclinical pharmacologic evaluation of pingyangmycin (author's transl)]. | | 1979 | 95444 |
| [chemical basis for the serologic specificity of the pseudotuberculosis microbe]. | | 1977 | 67731 |
| [antigenic analysis and immunological studies of the uterotropic bacterial strains sh6 and 01 isolated from aborted cows]. | the uterotropic strains sh6 and o1 were studied immunoelectrophoretically to establish their antigenic relationship. the more readily diffusing component of the o-antigenic fraction of the strains proved immunologically identical with lpa of the r brucella organisms, while the slower component showed common determinants with the o-antigenic fraction of yersinia pseudotuberculosis. immunodiffusion revealed that the o-antigenic fraction of the o1 strain and lpa of the s brucella organisms contain ... | 1976 | 60821 |
| [repeated microcycle in bacillus cereus]. | | 1978 | 96318 |
| unusual genes at the aminoterminus of human immunoglobulin variants. | | 1978 | 96346 |
| variant of stiff-man syndrome provoked by alcohol: case report. | | 1978 | 96364 |
| letter: yersinia infection with hepatitis in a physician. | | 1975 | 54845 |
| [oesophageal diverticulum in a pony (author's transl)]. | a case of oesophageal diverticulum in a pony is reported. the diagnosis was established by clinical and x-ray examination (following administration of a contrast agent) and verified by post-mortem studies. the cause and pathogenesis are discussed. | 1978 | 96547 |
| chelation in metal intoxication. vi. influence of pas and cdta on the excretion of manganese in rabbits given mno2. | the success of p-aminosalicyclic acid (pas) and 1,2-cyclohexylene dinitrilotetraacetic acid (cdta) in the mobilization of manganese from some vital organs and their subcellular fractions of manganese-intoxicated rats, led to the two compounds beng further investigated individually and in combination for their efficacy in influencing excretion of manganese in rabbits given mno2. these chelating agents led to a higher excretion of manganese through faeces than urine. whereas cdta was able to enhan ... | 1978 | 96549 |
| [prerequisites to the isolation of a group of polar infections]. | | 1979 | 38584 |
| [plp test as a rapid method for preliminary identification of yersinia enterocolica and yersinia pseudotuberculosis]. | | 1978 | 35722 |
| alertness, level of activity, and purposive movement following somatosensory deafferentation in monkeys. | | 1977 | 96722 |
| 5-thio-d-glucose is an acceptor for udp-galactose : d-glucose 1-galactosyltransferase. | | 1978 | 96819 |
| regulation of the in vitro synthesis of the alpha-peptide of beta-galactosidase directed by a restriction fragment of the lactose operon. | | 1978 | 96823 |
| phycobiliprotein synthesis in protoplasts of the unicellular cyanophyte, anacystis nidulans. | stable and metabolically active protoplasts were prepared from the unicellular cyanophyte, anacystis nidulans, by enzymatic digestion of the cell wall with 0.1% lysozyme. the yield of protoplasts from intact algal cells was approx. 50%. incorporation of l-[u-14c]leucine into cold trichloroacetic acid-insoluble material from protoplasts preparations was linear for 1.5 h and continued for an additional 2.5 h. incorporation of radiolabeled leucine into hot trichloroacetic acid-insoluble material fr ... | 1978 | 96857 |
| comparison of effects of normal rabbit sera and anti-cock sperm sera on rabbit sperm, including comparison of effects on the sex ratio. | | 1978 | 96880 |
| enterotoxicity of aeromonas hydrophila: skin responses and in vivo neutralisation. | culture filtrates and partially purified enterotoxins of 6 strains of aeromonas hydrophila isolated from faeces of diarrhoeic and healthy persons, drinking water, sewage and faeces of domestic animals caused induration and increased capillary permeability in skin of adult albino rabbits. the activities were less in crude enterotoxins indicating partial loss during purification. heat treatment for 30 min at 60 degrees c and 56 degrees c inactivated the induration and permeability effects of cultu ... | 1978 | 34953 |
| cinoxacin in female mongrel dogs: effect of urine ph on urinary drug excretion and correlation of in vitro characteristics of oral dosage forms with bioavailability. | | 1979 | 34019 |
| study on the ion-permeability of human dental enamel with special reference to an electrochemical approach. | | 1977 | 34011 |
| adenylylation/deadenylylation control of the glutamine synthetase of rhodopseudomonas capsulata. | | 1977 | 23287 |
| glutamine-requiring mutants of bacillus subtilis. | | 1977 | 23122 |
| value of sputum culture in diagnosis of pneumococcal pneumonia. | in our laboratory, culture of sputum was extremely useful in diagnosing the etiology of pneumococcal pneumonia. of 31 consecutive patients with bacteremic pneumococcal pneumonia, 29 (94%) had streptococcus pneumoniae cultured from sputum. recovery of pneumococci in culture was enhanced by anaerobic incubation as well as by a plate bile test and an optochin disk on a primary blood agar plate. | 1977 | 18489 |
| in vivo release of substance p in the cat substantia nigra. | push-pull cannuale were implanted into the substantia nigra (sn) and the caudate nucleus (cn) of the cat to study the in vivo release of substance p (sp), using a radioimmunoassay and high pressure liquid chromatography (hplc) analysis. the spontaneous release of sp could be detected in the sn and the cn. potassium (50 mm) locally applied stimulated sp release in both structures. furthermore an important evoked release of sp was observed in the sn during depolarization of striato-nigral sp fiber ... | 1979 | 93729 |
| [bacterial etiology of whipple's disease]. | | 1979 | 93668 |
| picosecond detection of bchl-800 as an intermediate electron carrier between selectively-excited p870 and bacteriopheophytin in rhodospirillum rubrum relaction centers. | | 1978 | 97097 |
| coagulation changes following vasectomy: a study in primates. | thirty vasectomized rhesus monkeys were tested for changes in coagulation factors that might reflect an increased incidence of thrombosis. the results of tests on these monkeys were compared with results of tests on 18 control rhesus monkeys; there were no significant differences between control and vasectomized animals for any of the parameters tested. one vasectomized animal had increased levels of fibrin monomer in his plasma on repeated samples, but no evidence of thrombosis on postmortem ex ... | 1978 | 97098 |
| surface-associated host proteins on virulent treponema pallidum. | a surface coat of host serum proteins was detected on virulent treponema pallidum by sodium dodecyl sulfate-gel electrophoresis. the loosely associated serum proteins could be removed by repeated washings in a protein-free medium. washed t. pallidum retained the ability to readsorb numerous host proteins from rabbit serum as well as iodinated rabbit or human albumin. in addition, various avidly associated host serum proteins including albumin, alpha(2)-macroglobulin, transferrin, ceruloplasmin, ... | 1979 | 93574 |
| effect of vitamin a acid on the growth of keratinocytes in culture. | the effect of vitamin a acid on the culture of guinea pig ear keratinocytes was investigated. use of this agent and treatment of the plastic dishes with collagen solution facilitated attachment and growth. vitamin a acid elicited a wave of dna synthesis which was studied by incorporation of tritiated thymidine and quantitation of cellular dna, particularly during the period 24--45 h after plating. during this period, thymidine incorporation into dna was increased ten-fold by vitamin a acid and s ... | 1978 | 93879 |
| nonrebreathing valve for spontaneously breathing or mechanically ventilated animals. | the design of a small dead space, nonbreathing valve suitable for use in small laboratory animals is presented. the design overcomes previous problems of condensation occurring at valve leaflets, and allows ongoing collection of expired gases should the animal require mechanical ventilation. the valve apparatus performs reliably when in operation for several hours at a time with a variety of small animals. | 1978 | 97251 |
| antimicrobial agents as preservatives in pharmaceutical and cosmetic products. agents as preservatives in eye-drops and contact lens solutions. | | 1978 | 97255 |
| a developmental model for studying choline acetyltransferase transport in chick motoneurons. | the proximodistal axonal transport of choline acetyltransferase (chac) has been studied in the chick sciatic nerve in the absence of any experimental manipulation. the phenomenon utilized by us is a physiological transient fall in the activity of chac. this fall occurs in most areas of the chick central nervous system after hatching, and moves toward the periphery along the nerves. having ruled out the presence of transient inhibitors, the movement of the fall towards skeletal muscles has been c ... | 1979 | 94010 |
| immunochemical studies of the inactivation of aspartate transcarbamylase by stationary phase bacillus subtilis cells. evidence for selective, energy-dependent degradation. | the aspartate transcarbamylase of bacillus subtilis is stable in exponentially growing cells, but undergoes rapid, energy-dependent inactivation when growth is inhibited by nutrient depletion or addition of antibiotics or other inhibitors of metabolism. this inactivation has been analyzed by a variety of immunochemical techniques, including direct and indirect immunoprecipitation of extracts of cells labeled with 3h-amino-acids, microcomplement fixation, and neutralization of enzymatic activity. ... | 1978 | 97299 |
| [quantitative determination of fibrinogen and fibrin degradation products by means of immunodiffusion]. | | 1979 | 94124 |
| the human ia system. | | 1979 | 94505 |
| purification of mouse interferon by sequential chromatography. | two schemes for the purification of mouse interferon are described, based on the concerted application of various physicochemical and affinity/adsorption column chromatographic techniques. mouse interferon was purified to a final specific activity of 1.0--8.0 x 10(8) units/mg when first precipitated with ammonium sulphate and further processed by hydrophobic chromatography and adsorption chromatography on affi-gel 202 and controlled pore glass. it was purified to a final specific activity of 2.5 ... | 1979 | 95020 |
| the pattern of sporulation in anabaena circinalis and comments on the role of heterocysts in sporulation in blue-green algae. | cells between two intercalary heterocysts differentiate at random into spores in a. circinalis. one or more cells, which fail to transform into spores, are present between the two adjacent spores, and these cells disorganize later. a critical c:n ratio regulates sporulation and heterocyst formation. during sporulation the reductive ability of the heterocyst gradually diminishes. it is concluded on the basis of this and other evidence that sporulation is regulated by interactions between heterocy ... | 1978 | 97869 |
| phosphorylcholine antigens from nippostrongylus brasiliensis. ii.--isolation and partial characterization of phosphorylcholine antigens from adult worm. | the phosphorylcholine antigens (c substance) were specifically isolated from nippostrongglus brasiliensis adult worms. they formed a gorup of fairly closely related molecules, but it was not possible to evidence that the carrier molecule was unique. an indirect immunoenzymatic test using immobilized lectins (concanavalin a, phytohaemagglutinin els, wheat germ agglutinin, recin types i and ii, peanut agglutinin) gave some light on the carbohydrate composition of the carrier molecules, whereas the ... | 1979 | 95087 |
| placental permeability in the sheep. | the transplacental flux of different radiolabelled substances was measured, according to fick's principle, in chronically catheterised pregnant sheep (124 to 143 days of gestation). knowing the uterine blood flow, it was possible to calculate the net flux and derive a permeability coefficient, k. with 14c erythritol, k soon reaches its ultimate value, thus suggesting there is only one rate-limiting step to transfer and no significant middle compartment in the sheep placenta. the comparison of fe ... | 1977 | 98093 |
| effects of ovarian hormones on cell membranes in the rat uterus. i. freeze fracture studies of the apical membrane of the liminal epithelium. | freeze fracture techniques have been used to study the apical membrane of cells of the luminal epithelium of the rat uterus under various hormonal regimes. in the ovariectomized but otherwise untreated rat, intramembranous particles (imps) occur at a density of 1395 +/- 122 per micron 2; they appeared spherical and uniformly distributed. after 3 days treatment with estrogen, no change in appearance or density was found, but 3 days of progesterone treatment produced a significant increase in imp ... | 1979 | 95176 |
| k562 human leukaemic cells synthesise embryonic haemoglobin in response to haemin. | | 1979 | 95354 |
| immunological relationships among transaldolases in the genus bifidobacterium. | antisera were prepared against electrophoretically homogeneous transaldolase (dihydroxyacetone transferase, e.c. 2.2.1.2.) of bifidobacterium thermophilum (b. ruminale) ru326 (atcc25866), b. cuniculi ra93 (atcc27916) and b. 'minimum' (homology group) f392 (atcc 27538). crude extracts of eighty six strains previously assigned to twenty one species of the genus bifidobacterium on the basis of deoxyribonouclelic acid (dna) homology (dna-dna hybridization), were compared by double diffusion tests on ... | 1979 | 95384 |
| a case of a needle stick. | | 1979 | 95411 |
| characterization of stem cells and progenitors of hemopoiesis by cell sorting. | cell sorting has been used as a method for characterizing hemopoietic stem cells and progenitors. fluorescent antibody-surface labels and changes in fluorescence polarization induced by in vitro stimulation with potential hemopoietic regulators were used. as detected by significant enrichment of cfu-s (pluripotent stem cells) in fluorescence-activated cell sorting, some cfu-s bear 'unique antigens' recognized by rabbit anti-human brain sera, human anti-human sperm sera, and 129 anti-f9 serum, bu ... | 1979 | 95516 |
| immunization with dextransucrases, levansucrases, and glycosidic hydrolases from oral streptococci. ii. immunization with glucosyltransferases, fructosyltransferases, and glycosidic hydrolases from oral streptococci in monkeys. | the feasibility of immunizing monkeys with enzymes from oral streptococci in an attempt to reduce dental caries was investigated. forty rhesus monkeys, macaca mulatta, were used. cariogenic streptococci, s mutans, were implanted into all the monkeys' mouths. there was no pathological effect resulting from immunization. of the 40 animals, 30 retained the implanted flora throughout the experiment; the remaining 10 were reimplanted until the streptococci remained. in six months, gross carious lesio ... | 1977 | 98540 |
| a microagglutination test for yersinia enterocolitica infection: recognition of multiple serotypes in experiments with stained suspensions of serotype o5,27. | when suspensions of yersinia enterocolitica were stained with triphenyl-tetrazolium chloride (ttc) their antigenic specificity, as determined by tube and microtitre-plate agglutination tests, was altered. thus, a ttc-stained suspension of serotype o5,27 detected antibodies to nine o serotypes of y. enterocolitica in sera from experimentally infected animals but did not cross-react with antisera to organisms of five other unrelated genera including brucella. the same suspension did, however, cros ... | 1978 | 98635 |
| [biosynthesis of penicillin upon periodic culturing of penicillium chrysogenum with an exponentially increasing glucose supply]. | penicillium chrysogenum was cultivated under controlled conditions and at constant specific growth rates regulated by glucose supply. the rate of penicillin synthesis (units/mg dry weight.hr) and pattern of time changes of the synthesizing capacity of the culture depended on the specific growth rate (hr-1). the arrest of penicillin synthesis was induced by the inherent changes of the culture rather than by external factors, e.g. use of substrates, changed limitation, accumulation of inhibitory m ... | 1979 | 95828 |
| the effects of sodium nitroprusside and trimethaphan camsylate on cerebral blood flow in rhesus monkeys. | hemispheric cerebral blood flow was measured in the rhesus monkey before and after infusion of the hypotensive agents sodium nitroprusside and trimethaphan camsylate. the intracarotid injections of 133xe was utilized, and flow was calculated by the "flow initial" technique. cerebral blood flow did not change significantly with the administration of trimethaphan camsylate. however, with a small reduction in blood pressure (10.6%) during the administration of sodium nitroprusside, the cerebral blo ... | 1978 | 98729 |
| phosphate transport in the proximal convolution of the rat kidney ii. effect of extracellular ca2+ and application of the ca2+ ionophore a 23187 in chronic ptx animals. | proximal inorganic phosphate (pi) transport was evaluated using the standing droplet method with simultaneous microperfusion of the peritubular blood capillaries. in chronic parathyroidectomized (ptx) rats addition of 3 micron of the ca2+ ionophore a 23187 to the luminal perfusate had no effect on the pi transport, although the isotonic fluid reabsorption was reduced by 20%. when the ca2+ concentration in the perfusates was raised from 1.5mm to 3.0mm the the reabsorption did not change signific ... | 1978 | 98754 |
| differentiation of mycobacteria by "in vivo" and "in vitro" delayed hypersensitivity reactions. | guinea pigs were sensitized with heat killed m. tuberculosis, m. kansasii, m. scrofulaceum, and m. avium-intracellulare. purified protein derivatives (ppds) prepared from each of these organisms were tested for delayed type hypersensitivity by lymphocyte transformation, macrophage migration, and mantoux type skin sensitivity tests. the homologous reactions were consistently more intense than heterologous reactions in all three procedures. the skin test procedure was more sensitive than either in ... | 1978 | 98814 |
| [the value of the immunodiffusion test in the diagnosis of animal histoplasmosis]. | a serological study which involved the agar gel immunodiffusion test of 11316 animal serum samples (porcine, bovine, equine and ovine cattles) was made in the havana province in an attempt to detect precipitation bands for histoplasma capsulatum. 135 porcine serum samples and 4 bovine serum samples were positive. | 1977 | 98818 |
| vascular dynamics of an experimental cerebral arteriovenous shunt in the primate. | an arteriovenous fistula which shunted arterial blood from the circle of willis to the internal jugular vein was created in ten monkeys. continued patency of the shunt was confirmed angiographically. cerebral blood flow measurements were then obtained with the shunt both open and occluded. flow was also determined in response to elevations of systemic arterial pressure and raised arterial carbon dioxide tensions (paco2), again with the shunt both patent and occluded. in addition, flow through th ... | 1978 | 98854 |
| [capsule formation in bac. anthracis on a carbon medium]. | | 1978 | 98898 |
| [some aspects relating to the aflatoxin generation during the self-heating of cereals]. | in a stored batch of grain which was already affected by mould-formation tests were carried out with the known aflatoxin producer aspergillus flavus. a significantly lower aflatoxin production ensued if the mould growth was not connected with self-heating of the stored product. however, in conformity with increasing mould formation the germinating power was adversely affected and the significant signs (fatty acid number, reductive and none-reductive sugars) were influenced in the grain, irreleve ... | 1978 | 98933 |
| effects of ethanol on pregnant rats and their offspring. | pregnant rats were intubated with either 1.0 or 2.0 g/kg of ethanol daily throughout gestation. pair-fed vehicle-treated, and nontreated rats fed ad libitum, served as control groups for ethanol-treated animals. ethanol treatment reduced food and water consumption and attenuated the gain in body weight of pregnant animals relative to nontreated animals fed ad libitum. litter size, litter weight, and the mean weight per pup were reduced in both the ethanol-treated and pair-fed control groups. the ... | 1978 | 96469 |
| [observation on the antigenic affinity of leptospira and brucella in the serological examination of cattle]. | 36,9% bovine serums which showed a non-specific reaction in examination for brucellosis had titre greater than or equal to 1:400 leptospirosis agglutinins. 15.1% of the serums showed a positive reaction (greater than 1:800), mostly those against l. sejroe and l. grippotyphosa. the cross reactions, found in individual cases within up to 39 days since the first reaction to brucellosis in cattle may signalize early leptospira infections. | 1978 | 96568 |
| the physiological disposition of the anti-tussive agent, 1,2,3,4a,9b-hexahydro-8,9b-dimethyl-4-[3-(4-methylpiperazin-1-yl)propionamido]dibenzofuran-3-one dihydrochloride azipranone, in man, rat, dog and baboon. | 1. the absorption, tissue distrigution, elimination and biotransformation of the anti-tussive agent azipranone labelled with 14c have been investigated after oral dosing to rat, dog, baboon and man and parenteral administration to rat and baboon. 2. levels of radioactivity in plasma were maximal within 20 min of dosing in the rat and after 1-2 h in the remaining species. the concn. declined thereafter with a half-life estimated at 1, 3-4 and 18-24 h for rat, dog, and baboon and man respectively. ... | 1978 | 96617 |
| pituitary responsiveness to lhrh and trh in adolescent girls. | puberty is characterized by a progressive maturation of the hypothalamus-pituitary gonadal axis which, in girls results in menarche. the first menstrual cycles are usually irregular and anovulatory, and the subtle positive and negative regulation of sex steroids on the hypothalamus-pituitary axis has probably not reached adult maturity. an investigation has been carried out in 99 normal adolescent girls, divided into 3 groups: 1-2, 3-4 and 5 years after menarche, by measuring basal hormonal valu ... | 1978 | 96896 |
| [radioimmunological aspects of neuropeptides]. | immunological aspects of neurosecretory peptides are relevant to antibody generation, labelling of peptides for radioimmunoassays and in particular the metabolism of neuropeptides. antibodies were generally produced by adsorption or polymerization (using different approaches and various coupling agents) of peptides with intrinsic antigenic molecules preceding their administration to recepient animals (rats, guinea pigs, rabbits and sheep) with adjuvants. antibodies were also obtained by injectin ... | 1978 | 96897 |
| ultraviolet light-induction and photoreactivation of thymine dimers in a cyanobacterium, anacystis nidulans. | partially photoreactivable mutant of anacystis nidulans demonstrates partial photorepair of thymine dimers. the wild type which is completely photoreactivable at the conditions studied shows higher level of thymine dimer photolysis. | 1978 | 100072 |
| single unit analysis of 'mirror foci' in chronic epileptic monkeys. | | 1978 | 96914 |
| external neuroanatomy of old world monkeys (cercopithecoidea). | | 1978 | 97050 |
| incorporation of amino acids by isolated submitochondrial fractions of lactating goat mammary gland in vitro. | incorporation of amino acids by mitochondria and its subfractions from mammary gland of the goat during lactation was studied in vitro. assessment of distribution of radioactivity incorporated by intact mitochondria into its subfractions revealed maximum specific activity in the inner membrane. during lactation the inner membrane of mitochondria exhibited further stimulation in such incorporation. matrix was the next active fraction whereas outer membrane and peripheral space had negligible radi ... | 1978 | 101564 |
| [new derivative of nitromidazole-tinidazole, for the treatment of giardiasis]. | the author treated 100 patients infected by giardia lamblia with a new antiprotozoal agent: tinidazole. the patients were divided in two groups: group i, composed of 50 patients were divided with a dosage of 300 mgm per day for seven consecutive days. the author obtained a cure rate of 96% (48 cases), and minimal side-effects were observed in 10% of the cases: nausea and headache, group ii also composed of 50 patients which were treated with a single dose of 2,0 gm. the parasitological cure obta ... | 1977 | 97162 |
| studies on virus-inhibiting substances of bacterial origin. iv. antiviral substances extractable from streptococcus faecalis: its in vivo effect. | | 1978 | 101714 |
| [effect of reserpine on the formation of 9,10-dimethyl-1,2-benzanthracene induced tumors in pinealectomized and thymectomized rats]. | after reserpine treatment the incidence of dimethylbenzanthracene-induced tumors was found to be significantly higher in pinealectomized rats than in intact or thymectomized ones. a very high rate of dmba-leukemia was observed in immune-deficient pinealectomized rats after reserpine administration. it is therefore suggested that the neuroendocrine disturbances due to removal of the pineal gland in the newborn animals, are latent and become evident after reserpine administration as reflected in a ... | 1978 | 101920 |
| effect of growth environment on pseudomonas aeruginosa killing by rabbit polymorphonuclear leudocytes and cationic proteins. | pseudomonas aeruginosa grown in a chemostat under carbon- and magnesium-limited conditions showed varying resistance to killing by rabbit peritoneal exudate polymorphonuclear leukocytes. slow-growing (d = 0.05 h-1), magnesium-limited cells were significantly more resistant to the lethal effects of the phagocytes than were fast-growing magnesium-limited cells and carbon-limited cells (d = 0.05 h-1 and d = 0.5 h-1, respectively). the resistance of magnesium-limited cells to killing by cationic pro ... | 1978 | 97227 |
| amino acid sequence of beta-galactosidase. viii. sequence of the nh2-terminal segment, cnbr peptides 1 to 9, residues 1 to 377. | the amino acids in 9 cyanogen bromide peptides have been placed in sequence starting from the nh2 terminus. the peptides account for residues 1 to 377 of the whole protein and include the largest (cnbr7, 119 residues) and the smallest (cnbr1, 2 residues) of the cyanogen bromide peptides. this region contains only 3 of the 20 lysine residues in the polypeptide chain. a high proportion of charged groups are present (28 of 66 arginine, 28 of 60 glutamic acid, and 24 of 65 aspartic acid residues). | 1978 | 97295 |
| on the interactions of yersinia strains and cell cultures. | comparative investigations were carried out on the dynamics of invasion of cell cultures by strains yersinia pestis ev and yersinia pseudotuberculosis treated vitally with petroleum ether. it was established that the invasiveness of the strains studied was related to the presence of chemical structures of the bacterial surface sensitive to the action of either and whose synthesis was temperature dependent. the penetration and initial stages of intracellular multiplication of the yersinia were ac ... | 1978 | 104477 |
| [study of the initial stages of microorganism growth and development for assessing the bactericidal action of chemical substances]. | | 1979 | 104902 |
| malignant transformation of a mouse epithelial cell line with polycyclic aromatic hydrocarbons. | | 1978 | 97564 |
| [reservoirs and wild vectors of trypanosoma cruzi. lxviii: infection of mammals by oral route]. | | 1978 | 97735 |
| [sarcocyst resistance to certain factors]. | | 1978 | 97852 |
| [chronic oral cadmium load in sheep. toxicological and pathomorphological studies]. | | 1978 | 106587 |
| inhibition of neisseria gonorrhoeae by normal human saliva. | saliva was found to be a powerful and specific inhibitor of neisseria gonorrhoeae. although 28 other species of bacteria were tested, including neisseria meningitidis, neisseria pharyngis var flava, neisseria lactamica, and neisseria catarrhalis, we failed to find any others sensitive to saliva under similar conditions. the physical properties of the inhibitory substance indicated that it might be salivary alpha-amylase. to test this hypothesis alpha-amylase was extracted from saliva and was sho ... | 1979 | 106919 |
| detection accuracy in chest radiography. | the detection accuracy of the diagnostic radiologist is important in everyday medical decision making. however, little work has been done relating the detection accuracy of the radiologist to the quality of the image. this study, using a thorax and lung phantom, simulated tissue-equivalent 6.4 mm lesions, and a 183 cm source-to-image distance, shows that the detection accuracy is not dependent on the focal spot size (over a range of 0.3-2.0 mm). however, the false positive rate increases when us ... | 1978 | 98003 |
| effects of various divalent cations on the survival of neisseria gonorrhoeae in liquid media. | the effect of various concentrations of divalent cations on survival of gonococci in liquid medium was studied. the growth of neisseria gonorrhoeae was inhibited by manganous chloride in concentrations above 1 x 10(-5)mol/l while the growth of control organisms such as neisseria meningitidis and escherichia coli was not inhibited by the same salt even at 1 x 10(-2)mol/l. copper sulphate, cobaltous nitrate, nickel chloride, and zinc sulphate also had deleterious effects on gonococci. magnesium ch ... | 1978 | 98204 |
| characteristics of pr5, a lipid-containing plasmid-dependent phage. | an extensive characterization of plasmid-dependent phage pr5 isolated from sewage has been carried out. the phage has a head diameter of 65--68 nm, is isometric with a double-layered capsid, and a minority possess tails. it adsorbs to many but not all types of bacteria possessing p, n, or w plasmids. the phage contains 20% lipid, 15.1% dna, and 64.9% protein by weight and has a buoyant density of 1.265 g/ml in cscl. the dna is double-stranded with a g + c content of 49% and a molecular weight of ... | 1978 | 98225 |
| [preparation of extracellular ribonuclease from bacillus subtilis]. | the paper describes a method for isolating alkaline ribonuclease from the culture liquid bacillus subtilis kp 349 which involved: submerged cultivation of the producer on complex and synthetic nutrient media with optimized rnase activity, acid treatment of the total culture liquid, and filtration through perlite. further treatment may include either spray drying of the culture liquid filtrate or its concentration in a vacuum evaporator, dialysis of the concentrate against distilled water, and d ... | 1978 | 107517 |