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approach to a practical method for screening and identifying microorganism genera from urine (author's transl).in this study the author reported upon a practical new system for screening and identifying the microbial agents causing urinary tract infections. this system is composed of a combination of 3 screening procedures (ph-value + nitrite-test + catalase-test) and 8 selective culture media for the purpose of genus identification within 24 hours (uripret-g). a total of 130 cultures was investigated. the employed microorganisms were mainly recovered from urine samples. they included the following speci ...197611179
1-n hapa gentamicin b, a new aminoglycoside active against gentamicin resistant isolates--activity compared to other aminoglycosides.1-n hapa gentamicin b is a new aminoglycoside active against most enterobacteriaceae, pseudomonas aeruginosa and staphylococcus aureus. among 504 clinical isolates at a concentration of 12.5 microgram/ml all staph. aureus, escherichia coli, klebsiella, enterobacter, proteus rettgeri, providencia and 78% of pseudomonas, 86% of proteus morganii were inhibited. like other aminoglycosides, the activity was greatest at an alkaline ph and reduced by high cations concentrations. 1-n hapa gentamicin b w ...197827494
similarity of casein- and endotoxin-induced, myeloma- associated and aged sjl/j amyloid in various strains of mice.amyloidosis was induced in a number of strains of mice by repeated injections of casein and endotoxin. spontaneous amyloid was obtained from balb/c mice bearing a myeloma tumor (igg2a producing mopc 173 tumor) and from aged sjl/j mice. both the induced and spontaneous forms were similar in their size, immunological reactivity, peptide maps and in the susceptibility of histological sections to oxidizing agents with or without trypsin digestion. since case-induced murine amyloid resembles the noni ...197987374
moloney virus-induced cell surface antigens and histocompatibility antigens are located on distinct molecules. 197987439
the role of p23,30-bearing human macrophages in antigen-induced t lymphocyte responses. 197988270
fuorescent retrograde neuronal labeling in rat by means of substances binding specifically to adenine-thymine rich dna.six fluorescent substances, binding specifically to adenine-thymine rich dna, were injected in rat caudate-putamen. this resulted in retrograde axonal transport and fluorescent retrograde labeling of neurons in center-medium parafascicular nucleus, substantia nigra and dorsal raphe. two of these substances, i.e. "true blue' and 'granular blue', give a very striking blue fluorescent retrograde neuronal labeling. mid-thoracic spinal injections of these two substances in rat also resulted in a pron ...197988697
[post-extrasystolic and post-pacing potentiation. i. experimental study of the isolated heart of the rabbit]. 197888947
reaction of cells from early chick embryos with antiserum against mouse sperm cells. 197989009
preparative isolation of the cell receptor for immunoglobulin e. 197989114
alpha-fetoprotein as a carrier protein in plasma and its bilirubin-binding ability.the bilirubin-binding ability of human alpha-fetoproteins, which were purified from fetal cord serum and from ascites fluid of a hepatoma-bearing patient, was examined by the difference spectrum and the jacobsen peroxidase methods. the difference spectrum observed as a result of the specific binding of bilirubin to alpha-fetoprotein had a maximum at 482 nm, and this pattern was quite similar to that observed for serum albumin. the result obtained by the difference spectrum method showed that 1 m ...197989900
identification of the primate papovavirus hd as the stump-tailed macaque virus.the recently isolated primate papovavirus hd is shown to be indistinguishable from the stump-tailed macaque virus by immunofluorescent reactivity, by restriction endonuclease analysis, and by nucleic acid hybridization assay.197990163
in vitro studies of the replication of moloney murine leukemia virus. 197990575
tobacco leaf mesophyll peroxidase. isolation, purification and some properties.two isoperoxidases, p1 and p2, were isolated from tobacco mesophyll leaves by the combined methods of ammonium sulphate precipitation, page and deae-cellulose column chromatography. the ph otpima for p1 and p2 were 7.0 and 7.5 respectively. the values of km for h2o2 were 1.82 and 0.87 mm for p1 and p2. results from this investigationsuggest that these isoperoxidases differ in their electrophoretic, catalytic and physical properties.197990669
["non-specific cross reacting antigen (nca)", a tracer of human granulocytes and monocytes].the non specific cross reacting antigen, or nca, is a normal tissue antigen that cross reacts with cea. it bears a specific antigenic determinant that is absent from cea. immunocytological studies first pointed out that nca, but not cea, is present in alveolar macrophages and polymorphonuclears. further work demonstrated that nca is a marker of granulocytic series: it appears at the stage of promyelocyte and likely is linked to the azurophilic granules. the same antigen is also present in periph ...197992357
cytochemical detection of peroxisomal oxidases. 197992494
from the nichd. national institute of child health and human development. predictors of hereditary disease or congenital defects. 197993264
thyroid hormone regulation of alpha-adrenergic receptors: studies in rat myocardium.the effects of alterations in thyroid state on cardiac alpha-adrenergic receptors were investigated by the binding of [3h]dihydroergocryptine (dhe), a potent alpha-adrenergic antagonist. in seven experiments, cardiac membranes from euthyroid rats bound 47 +/- 9 fmoles dhe/mg protein (mean +/- se) at saturation and demonstrated a dissociation constant (kd) of 2.5 +/- 0.4 nm. hyperthyroidism, produced by parenteral injection of triiodothyronine, significantly reduced the binding of dhe at all conc ...197994388
[the behaviour of some histochemical reactions in testicle tissue of a white rat as a result of kaptan action (author's transl)]. 197894984
[immunological problems in oncology (author's transl)].the authors, after a view of the problems of immunology, regarding the most recent discoveries, deal with the conclusions about the immunological reactions in research and clinical oncology. many specific antibodies, formed as a result of the tumor, have been discovered in the field of research. it is impossible to say the same about human tumors and the probable hypothesis are numerous. the results until now obtained, even if they don't give a definite response, show that the immune defense of ...197995475
brain and liver aldehyde dehydrogenase activity and voluntary ethanol consumption by rats: relations to strain, sex, and age.voluntary ethanol consumption and brain and liver aldehyde dehydrogenase (aldh) activity were measured in male and female rats of the tryon maze-bright (s1), tryon maze-dull (s3), and wistar strains. the levels of brain aldh measured in the different groups, corresponded well to the levels of ethanol consumption, while differences in liver aldh corresponded well to only the strain differences in ethanol intake. within individual groups, levels of ethanol consumption correlated better with levels ...197896475
development of visual acuity in infant monkeys (macaca nemestrina) during the early postnatal weeks. 197896592
transcription and translation in a pleiotropic streptomycin-resistant mutant of escherichia coli.the role of the ribosomal protein s12 (streptomycin protein) in ribosome function and in other metabolic processes in the cell has been investigated. a spontaneous streptomycin-resistant strain of escherichia coli (sm3) carrying a mutation in the rpsl gene is deficient in its ability to induce the synthesis of the enzyme bets-galactosidase. it was demonstrated that the reduced rate of enzyme synthesis results from deficiencies in both the transcription of the lactose operon and translation of th ...1979104958
[b. cereus count in meat and dairy food products].studies were carried out to establish the contamination of some meat and dairy food products with b. cereus. a total of 48 heat-treated sausages (32 perishable and 16 durable) and 64 batches of pasteurized milk were sampled. it was found that 25 per cent of investigated sausage samples contained b. cereus. perishables proved to a considerable extent more frequently contaminated (33.3 per cent). the count of b. cereus in such products ranged from 10(1) to 10(3) per g. however, pasteurized milk wa ...1978105462
competition of beta-lactam antibiotics for the penicillin-binding proteins of pseudomonas aeruginosa, enterobacter cloacae, klebsiella aerogenes, proteus rettgeri, and escherichia coli: comparison with antibacterial activity and effects upon bacterial morphology.the competition of a number of beta-lactam morphogenic probes for the penicillin-binding proteins (pbps) of pseudomonas aeruginosa, enterobacter cloacae, klebsiella aerogenes, proteus rettgeri, and escherichia coli has been studied. the results indicate that the various gram-negative bacteria have similar, but not identical, pbp patterns and that the individual proteins probably perform similar morphogenic functions as in e. coli k-12. comparison of the 50% binding concentrations of the compound ...1979116592
immunization against experimental trypanosoma cruzi infection: inherent difficulties of a uniform comparative evaluation of antigenic preparations. 1979120626
[frequency and antibiotic resistance of bacteria isolated from urine cultures].the aa report the data pertinent to the urine culture performed during a year in the sanitary and prophylactic laboratory of the district of l'aquila. in urine samples with number of bacteria > 10(5)/ml have been found e. coli (49%), proteus mirabilis (32%), pseudomonas aeruginosa (12%), staphylococcus aureus (5%), proteus rettgeri (1%), enterococco (1%). the data are also reported concerning germ resistance to several antibiotics.1979121968
amino-acid sequence of the cyanogen-bromide fragment from human plasminogen that forms the linkage between the plasmin chains.the complete amino acid sequence of a cyanogen bromide fragment (122 residues) obtained from plasminogen is described. this fragment forms the overlap between heavy (a) and light (b) chains of human plasmin. the particular arginyl-valyl bond cleaved in the second step of the activation process is shown to be arg98-val99 in this fragment. this site is not very similar to the one in the nh2-terminal part of the molecule (arg68-met69). remarkable homologies with the 'triple loops' ('kringle structu ...1975126863
characterization of 5.8s ribosomal ribonucleic acid in neurospora crassa.neurospora crassa ribosomes contain a species of ribonucleic acid (rna) of molecular weight 54,000, similar to 5.8s ribosomal rna previously described for other eukaryotic organisms. the 5.8s rna from n. crassa was found to be released by heat treatment at 60 c from 25s ribosomal rna but not from 18s ribosomal rna. the base composition of n. crassa 5.8s rna was similar to that of 5.8s rna from saccharomyces cerevisiae, but differed from animal 5.8s rna. during the course of this study, it was di ...1975126993
[muscular clearance after administration of phenoxybenzamine in shock].the authors made an experimental investigation in the dog concerning the evolution of the muscular clearance of phenoxybenzamine in the course of de-shocking procedures. the animals were shocked by hemorrhage and were treated by perfusion of volemic mass and administration of phenoxybenzamine. this substance was flowed in paralell with the hemodynamic parameters and the rhythm of the diuresis. it was noted that the direction and the amplitude of changes concerning the half-life of na131i do not ...1975127228
[experiments and theoretical cell kinetic calculations on the problem of in vivo synchronization with vincristine in l 1210 ascites tumor cells and crypt cells of the mouse (author's transl)].experiments are described on synchronizing l 1210 ascites tumor cells and jejunal crypt cells of the mouse with vincristine. in both cases the percentage of mitoses increases to a peak value 4 hrs after application of vincristine and decreases during the following 8 hrs ("releasing time") to the level of the normal mitotic index. following this first mitotic peak no futher peak of neither the mitotic nor the labeling index was observed during 48 hrs in l 1210 ascites tumor cells and during 38 hr ...1975127443
[veterinary-sanitary measures on turkey farms]. 1975129930
[proteus rettgeri strains, resistant to gentamicin with transmissible resistance to kanamycin and carbenicillin (author's transl)]. 1977144028
[immunoprofile of lmif in immunologic deficiency syndromes. ii. mediator production by isolated subpopulations of human lymphocytes]. 1978149303
occupational allergic contact dermatitis to virginiamycin, an antibiotic used as a food additive for pigs and poultry.a warehouseman aged 31 working in a pharmaceutical factory got an occupational contact dermatitis to virginiamycin (factor m), an antibiotic used as a food additive for pigs and poultry. a review is made of contact dermatitis to virginiamycin and to pristinamycin.1978149638
evaluation of a proteus rettgeri o-serotyping system for epidemiological investigation.an evaluation of the serotyping system for proteus rettgeri has been performed through its application to 561 human isolates of this species. of these, 545 were typable and could be separated into 58 o serotypes. a group of isolates from one hospital, and clinically implicated in cross-infections, was found to belong the same o serotype, confirming the clinical findings. isolates with more than one specificity of thermostable antigen, in most cases, were found to have combinations of such specif ...197657120
immunological methods employed in an attempt to induce erythema nodosum leprosum (enl) in mice.in the mouse foot pad model five different parameters were employed to simulate the condition of enl as observed in the human. the experimental groups with five to six months leprosy infection were injected intravenously with various anti-mycobacterial antibodies, m. leprae sonicate and 'b' cells obtained from syngenic donors. the control group of animals, infected similarly, were treated either with m. leprae sonicate or gamma globulins precipitated from normal human serum. all recipients were ...1978151764
antagonism of the antibacterial action of some penicillins by other penicillins and cephalosporins.there are many examples of two penicillins acting synergistically, usually by one competitively inhibiting beta-lactamase, thus protecting the other from inactivation. there are few reports on penicillins antagonizing each other. eight strains of three genera (proteus, escherichia, pseudomonas) isolated at boston city hospital or institut pasteur, paris, showed antagonism of carbenicillin or ampicillin by cephaloridine, cloxacillin, or 6-aminopenicillanic acid. broth dilution tests showed that w ...1975163847
hydrophobic interactions of the apo-gln-i polypeptide component of human high density serum lipoprotein.apo-gln-i, the major polypeptide component of human serum high density lipoprotein, has four noninteracting hydrophobic sites which associate with alkanes, anionic detergents, and cationic detergents. hexane and octane bind to these sites with association constants of 6.8 times 10-2 and 1.8 times 10-4 liters/mol, respectively, and compete with the anionic detergent, sodium dodecyl sulfate (c12oso3-minus), at low detergent ligand binding ratios (i.e. smaller than or equal to 1.0 mol of c12oso3-mi ...1975165177
the ultrastructure of the sensory end-organs (baroreceptors) in the atrial endocardium of young mini-pigs.light and electron microscopical studies on pig hearts have confirmed the presence in the right and the left atrial endocardium of distinct circumscribed, unencapsulated end-organs (baroreceptors) associated with 4-9 mum thick nerve fibres. the myelin sheath terminates before the entrance of the nerve into the end-organ. the regular presence of thin axon profiles containing clusters of small agranular vesicles, both around the thick nerve fibre and in the periphery of the end-organs, suggests a ...1975166065
scanning electron microscopy of glucocrticoid-treated hepatocytes and hepatoma cells in culture.the morphological effects of exposure to hydrocortisone have been examined in two cell lines of liver origin by scanning electon microscopy. in one of these, an aneuploid line derived from a morris hepatoma, the presence of hormone results not only in a suppression of cell proliferation, but in a marked flattening of the cells and loss of surface microvilli; in the other cell line, a diploid line derived from adult rat liver, the suppression of cell division is less marked, and the morphological ...1975171679
catecholamine secretion by isolated adrenal cells.isolated adrenal cells were prepared by collagenase digestion of guinea pig adrenal glands. acetylcholine stimulates the secretion of catecholamines by these isolated adrenal cells. acetylcholine-stimulated catecholamine secretion is inhibited by cholinergic blocking agents (atropine and hexamethonium) and by local anaesthetics (tetracaine), and is dependent upon the concentration of ca2+ in the incubation medium. in the presence of ca2+, catecholamine secretion is also stimulated by two divalen ...1976174736
[immunologic results obtained with an experimental system oftransplantable colonic tumors. possible applications of these results to human intestinal tumors].intestinal cancers, morphologically very close to human colo-rectal adeno-carcinoma, have been induced by dimethylhydrazine in inbred rats. graftable lines have been obtained from 5 primary intestinal tumors, and 3 cell lines have been cultivated from the grafts. this model was used to demonstrate carcinofetal antigen(s) on the surface of the intestinal cancer cells. circulating antibodies against tumor-associated antigen(s) have been found in tumor-bearing rats. cancer enhancement was regularly ...1975174767
airborne transmission of polyoma virus.polyoma virus (pv) infection was transmitted through the air of an animal laboratory. mice free of detectable antibodies to pv were exposed for 1 month to the airborne environment of laboratories housing naturally infected mice. the seroconversion rate was 75% (24/32), as measured by hemagglutination inhibition. control mice, housed in the sterile atmosphere of a mass air flow cabinet (mafc) in the same laboratory, had a seroconversion rate of 15.8% (3/19). airborne transmission occurred bia pv ...1976176376
phosphorylated sites of calf thymus h2b histone by adenosine 3':5'-monophosphate-dependent protein kinase from bovine cerebellum. 1976183776
the functional relationship between polymerization and catalytic activity of beef liver glutamate dehydrogenase. ii. experiment. 1976187756
[synthesis of virus-specific rna under conditions of homologous and heterologous interference by newcastle disease virus].homologous and heterologous interference by newcastle disease virus (ndv) was manifested in a marked inhibition of virus-specific rna synthesis of both the interacting viruses. inactivation of the interfering ndv by irradiation reduced its capacity to inhibit the synthesis of virus-specific rna of the homologous virus, leaving its effect on the synthesis of rna of the heterologous virus unchanged. in contrast, treatment of cell cultures with heparin leading to reduced interferon production elimi ...1976188251
subcellular distribution of steroids in rat adrenocortical tissue after incubation in vitro [proceedings]. 1977194992
epstein-barr virus-specific rna. iii. mapping of dna encoding viral rna in restringent infection.namalwa and raji cells, originally obtained from a burkitt tumor biopsy, grow as continuous cell lines in vitro and contain the epstein-barr virus (ebv)-related nuclear antigen ebna (b. m. reedman and g. klein, int. j. cancer 11:499-520, 1973) and rna homologous to at least 17 and 30% of the ebv genome, respectively (s. d. hayward and e. kieff, j. virol. 18:518-525, 1976; t. orellana and e. kieff, j. virol. 22:321-330, 1977). the polyribosomal and polyadenylated [poly(a)+] rna fractions of namal ...1979219221
l-amino acid oxidases of proteus rettgeri.proteus rettgeri has been found to contain two separable 1-amino acid oxidases. both enzymes are particulate in nature, neither being ribosomal bound. one of these enzymes appears to have broad specificity, being active toward monoaminomonocarboxylic, imino, aromatic, sulfur-containing, and beta-hydroxyamino acids. the other enzyme has more limited specificity, catalyzing the oxidative deamination of the basic amino acids and citrulline. the affinity of this oxidase for the various substrates at ...1975234421
allantoin racemase: a new enzyme from pseudomonas species.1. allantoin racemase is a novel enzyme which catalyzes the conversion of s(+)-and r(minus)-allantoin into the racemate. 2. the enzyme is present in pseudomonas testosteroni, pseudomonas putida and five biotypes of pseudomonas fluorescens, but absent in a number of other pseudomonas species. 3. the enzyme of ps. testosteroni was purified 133-fold and exposes optimal activity at ph 8.0-8.2 and 50 degrees c. the enzyme is stable on heating for 15 min at 70 degrees c. 4. the enzyme appeared to be s ...1975237557
[in vitro antibacterial activity of tobramycin used in combination with cephalothin or carbenicillin (author's transl)].combinations of tobramycin (tob) with cephalothin (cet) or carbenicillin (cbpc) were evaluated by in vitro test against 161 clinical isolates of klebsiella pneumoniae, escherichia coli, indole-positive proteus, enterobacter and serratia marcescens which were not inhibited by 6.25 microgram/ml of cet. the combinations were considered to show synergy when there was a 4-fold or greater reduction in mic values (fic index less than or equal to 0.5) of both antibiotics when combined. synergy of tob wi ...1978246946
comparative study of amikacin (bb-k8) and gentamicin activity in vitro against proteus rettgeri. 1977268183
cardiolipin: a stereospecifically spin-labeled analogue and its specific enzymic hydrolysis.the spin-labeled cardiolipin 1-(3-sn-phosphatidyl)-3-[1-acyl-2-(16-doxylstearoyl)glycero(3)phosphol]-sn-glycerol has been prepared. the stereoselective synthesis makes use of the monolysocardiolipin 1-(3-sn-phosphatidyl)-3-[1-acyl-2-lyso-sn-glycero(3)phospho]-sn-glycerol, available from the stereospecific hydrolysis of cardiolipin by phospholipase a2 (phosphatide 2-acylhydrolase, ec 3.1.1.4) of trimeresurus flavoviridis. the results of treatment of the spin-labeled cardiolipin with the cardiolip ...1978274715
[a study on periodontal dressing materials. part 8. the effect of periodontal dressing materials on the capillary permeability of subcutaneous tissue of rabbit==especially, an effect of individual ingredients consisting of liquid materials (author's transl)]. 1978296222
the identification of new rna-binding proteins in the escherichia coli ribosome. 1977321250
therapy for experimental intraabdominal sepsis: comparison of four cephalosporins with clindamycin plus gentamicin.an experimental model of intraabdominal sepsis in rats was used for evaluation of treatment with four cephalosporins: cephalothin, cefazolin, cefoxitin, and cefamandole. doses were 115 mg of each of the cephalosporins/kg and, in additional experiments, 350 mg of cephalothin or cefazolin/kg. response to treatment was evaluated by mortality rate and the incidence of intraabdominal abscess. all four cephalosporins and gentamicin produced a similar reduction in mortality rates. there was a marked va ...1977321707
resistance to gentamicin: a growing concern.gentaminic was introduced in 1969 as a broad-spectrum aminoglycoside effective in vitro against a majority of aerobic gram-negative bacilli. in recent years gentamicin-resistant clinical isolates have become more prevalent. in our laboratory in 1975, 32% of pseudomonas sp and 44% of indole-negative proteus sp isolates were resistant to gentamicin. resistance to tobramycin is also increasing; 24% of escherichia coli and 28% of indole-negative proteus sp isolates were found to be tobramycin-resist ...1977322294
esculin hydrolysis by enterobacteriaceae.literature reports disagree concerning esculin hydrolysis in the family enterobacteriaceae. a total of 2,490 strains of the family were investigated for esculin hydrolysis by two methods, the esculin spot test and the pathotec incubation strip, which measures constitutive enzyme, and five growth-supporting methods, which determine both constitutive and inducible enzymes. the five growth-supporting media studied were: vaughn-levine, the standard esculin hydrolysis medium (p. r. edwards and w. h. ...1977330558
unusual enterobacteriaceae. "proteus rettgeri" that "change" into providencia stuartii.a blood culture bottle from a patient with bacteremia contained both proteus rettgeri biogroup 5 and providencia stuartii (described in bergey's manual of determinative bactiology [8th ed., 1974] as proteus inconstans), which had the same unusual antibiotic resistance pattern. single colonies of this p. rettgeri biogroup 5 isolate were shown to produce urea- clones. if current taxonomy is used, the strain changed from p. rettgeri to p. stuartii in the laboratory and probably also in the patient. ...1977334793
removal of non-specific antibodies from tetanus antitoxin serum by affinity chromatography using the antigens of a nontoxigenic derivative of clostridium tetani. 1977352339
casein and alpha-lactalbumin detection in breast cancer cells by immunocytochemistry.casein and alpha-lactalbumin are characteristic proteins produced by normal mammary cells under hormonal stimulation. specific antisera were used to immunochemically stain for these two proteins in the unstimulated r3230ac transplantable rat mammary tumor as well as in normal lactating rat mammary tissue. specific staining was observed in the lactating rat alveolar epithelial cells and in the cells lining the intraalveolar ducts with both antisera. in the r3230ac tumor some cells were shown to c ...1978352508
a simple allogeneic test system for the study of antibody-dependent cellular cytotoxicity (adcc) in man.a simple allogeneic test system for the study of adcc activity of human mononuclear peripheral blood leucocytes (mpbl) is presented. the test uses human rh-positive erythrocytes as target cells coated with specific human igg antibody. the effector function of human mpbl is demonstrated after depletion of most of the monocytes and b lymphocytes on nylon wool column. the test system seems to be useful in the clinical study of adcc activity in man.1977352854
typing methods for proteus rettgeri: comparison of biotype, antibiograms, serotype, and bacteriocin production.two hunderd five strains of proteus rettgeri from epidemic and nonepidemic sources were differentiated by a new biotyping scheme, agglutination in o antisera, antimicrobial resistance patterns, and a new scheme based on bacteriocin production. the p. rettgeri were divided into 10 groups by their fermentation of lactose, sucrose, d-mannitol, and salicin. these groups were then subdivided into 19 biotypes by other biochemical reactions. bacteriocin production was tested by the cross-streak method. ...1978370146
in vitro investigations with fosfomycin on mueller-hinton agar with and without glucose-6-phosphate.determination of the minimal inhibitory concentration of fosfomycin in the agar dilution test on mueller-hinton agar showed that the addition of glucose-6-phosphate to the nutrient medium potentiates the action of fosfomycin against escherichia coli, klebsiella, enterobacter, citrobacter and staphylococcus aureus, sometimes by as much as 256-fold. such a potentiation of action was not detectable with serratia marcescens, the individual proteus species, pseudomonas aeruginosa or enterococci. fosf ...1979389806
[reservoir for bacteria of urinary tract infections in urologic patients (author's transl)].many infections of the urinary tract, especially after surgical treatment are nosocomial infections. the etiological bacteria could only be found in the urine of the infected patients and in the faecal flora of nearly 40% of all stationary patients. the so called "problem bacteria": klebsiella, proteus rettgeri, pseudomonas showed increasing drug resistance during the observed period between 1972-1975. the bacteria isolated from the faecal flora also showed multiple drug resistance. thus we conc ...1977404234
[a simple method for the determination of pcb in human milk and blood using an improved essential oil distillator (author's transl)]. 1977404452
lack of effect of an antifibrinolytic agent on cholesterol-induced aortic lesions in the rat, with observations on the independence of intimal foam cell lesions and extracellular medial lipid. 1979421861
effect of central venous pressure on arterial baroreflex control of heart rate.there is considerable evidence that the level of afferent cardiopulmonary receptor activity modulates sinus node responses to arterial baroreflex stimulation in experimental animals. we tested the hypothesis that this reflex interaction occurs also in man by measuring sinus node responses to arterial baroreceptor stimulation with phenylephrine injection or neck suction, before and during changes of central venous pressure provoked by lower body negative pressure or leg and lower trunk elevation. ...1979434172
the contracture produced in tracheal smooth muscle by anticholinesterases [proceedings]. 1979497580
an xyy man.this case report describes a young man with a 47, xyy karyotype who was convicted of arson. he suffered from a cardiac disorder which may well have been part of the xyy syndrome rather than a chance association. his abnormal karyotype was disclosed in court and used by the defence in a plea in mitigation.1979497632
spinal analgesia and sedation of goats with lignocaine and xylazine.spinal anaesthesia of 20 does undergoing laparotomies was accomplished with epidural injections of 2 per cent lignocaine at a dosage of 1 ml per 4.55 kg in 16 goats. epidural injection resulted in paralysis lasting 198.5 minutes +/- 36.6 minutes. subarachnlid injection resulted in paralysis lasting 180.8 minutes +/- 44.9 minutes. xylazine was given intramuscularly at the dosage of 0.11 mg per kg after posterior paralysis was complete. these treatments resulted in effective analgesia for surgical ...1979516312
application of o-serotyping in a study of providencia rettgeri (proteus rettgeri) isolated from human and nonhuman sources.a somatic (o) antigen serotyping scheme for providencia rettgeri (proteus rettgeri) was modified to exclude o-type strains recently reclassified as urea-positive providencia stuartii and was extended to include new serotypes to provide for serotyping on the basis of 93 o-antigens. isolates from two hospitals, five public health laboratories, and nonhuman sources (polluted water and frogs) were serotyped. the 112 isolates collected from a large general hospital over a 99-month period were distrib ...1979521481
[problems of the disease due to mycobacteria other than tubercle bacilli: surgical treatment and indication (author's transl)]. 1979522352
[antibacterial kinetics of fosfomycin (author's transl)].the authors studied, with the autobac machine, the kinetics of antibacterial activity of fosfomycin against staphylococcus aureus, streptococcus d' streptococcus pneumoniae, neisseria meningitidis, acinetobactor lwoffi, haemophilus influenzae, salmonella typhimurium, escherichia coli, proteus rettgeri, klebsiella pneumoniae, serratia marcescens and pseudomonas aeruginosa. a correlation appears between the kinetics of fosformycin antibacterial action and the microbial growth rate.1979547759
r plasmids in gentamicin-tobramycin-carbenicillin-resistant nosocomial strains of proteus rettgeri and proteus morgani. 1978570994
proteus rettgeri infections: a review.proteus rettgeri is an aerobic gram-negative bacillus that displays marked resistance against most of the antibiotics presently available. this organism causes infections usually confined to the urinary tract of certain types of compromised patients. occasionally, it is recovered from soft tissue abscesses, and rarely from the blood and respiratory tract. proteus rettgeri is notorious for causing nosocomial outbreaks of urinary tract infections in urological and physical medicine wards. our expe ...1977583779
[partial t antigen on red blood cells from a patient with urinary infection due to proteus rettgeri]. 1977601403
[the etiology of urinary tract infections].the authors have planned a program in order to file and elaborate with a computer the results of urine cultures. from 8.600 specimens, about 86% were negative or doubtful. the data obtained from 1201 positive cultures were processed in order to state the absolute and relative frequency of the bacterial species isolated and their distribution according to their genera, antibiotic resistence, month and sex. among the most representative species the pattern of antibiotic resistence was surveyed. e. ...1977615747
chemotherapeutic evaluation of 5-episisomicin (sch 22591), a new semisynthetic aminoglycoside.5-episisomicin (sch 22591) is a novel semisynthetic aminoglycoside with a spectrum and potency similar to gentamicin in its activity against susceptible bacterial strains, but with increased potency against pseudomonas, providencia, and proteus rettgeri. it is also more active than tobramycin and amikacin against these last-mentioned species.against resistant strains, sch 22591 is significantly more active than gentamicin or tobramycin. against resistant gram-negative bacteria other than pseudom ...1978626490
[importance of research on antibacterial substances in the study of bacteriurias].a study was made of 1050 urine specimens from the nephro-urological and geriatric departments of the malpighi hospital to see how many percent contained antibacterial substances and the incidence of bacteria species. 26.5% contained antibacterial substances. proteus rettgeri was significantly more frequent in specimens containing such substances, whereas staphylococci were significantly more frequent in the remainder.1978662157
pharmacology and efficacy of netilmicin.twenty-six patients, 20 to 77 years of age, were treated with netilmicin, mean dose 2 mg/kg every 8 h intramuscularly or in a 20-min intravenous infusion. the mean serum half-lives in patients with creatinine clearances of >/=90 ml/min and 60 to 90 ml/min were 3.2 and 3.4 h, respectively. in patients with serum creatinines of </=1.4 mg/100 ml and creatinine clearances of >/=60 ml/min, mean serum levels were 9.0 and 1.2 mug/ml, respectively, 5 to 15 min and 7.5 h post-intravenous infusion, and 7. ...1978666303
cross-protection of mice provided by active and passive immunization against experimental infections with virulent proteus rettgeri and providencia bacteria.immunization with providencia and proteus rettgeri formalin-treated bacterial suspensions produced high levels of protection in mice against homologous and heterologous challenge. mice were also cross-protected, but less effectively, by passive administration of rabbit type-specific antisera. the protective activity appeared to be due to an antigen common to strains of different o-serotypes. it was not detectable in agglutination reactions, and preliminary results indicate that it is thermostabl ...1978669801
in vitro studies with sch 21420 and sch 22591: activity in comparison with six other aminoglycosides and synergy with penicillin against enterococci.in vitro tests were performed with sch 21420 and sch 22591 to determine (i) their activity in comparison to six other aminoglycosides against 343 clinical isolates, and (ii) whether synergy with penicillin g could be demonstrated with enterococci. in broth dilution tests, sch 22591 was more active than the seven other aminoglycosides against staphylococcus aureus, enterobacteriaceae, and most nonfermenting gram-negative bacilli. sch 22591 was as active as tobramycin against pseudomonas aeruginos ...1978697346
sce-963, a new broad-spectrum cephalosporin: in vitro and in vivo antibacterial activities.sce-963 {7beta-[2-(2-aminothiazol-4-yl)acetamido]-3-[({1-(2-dimethylaminoethyl)- 1h-tetrazol-5-yl}thio)methyl]-ceph-3-em-4-carboxylic acid}, a new semisynthetic cephalosporin, showed excellent antibacterial activity against gram-positive and gram-negative bacteria, including haemophilus influenzae, indole-positive proteus, enterobacter species, and citrobacter freundii. the minimum inhibitory concentrations of sce-963 against most strains of clinically isolated escherichia coli, klebsiella pneum ...1978718154
[r factors in proteus rettgeri strains]. 1978742932
[characteristics of the enterobacteria strains isolated from the urine in urinary tract infections].study of biochemical properties of 421 strains of enterobacteria permitted to refer them to the following taxonomic groups of which e. coli constituted 83,4 +/- 3.6%, enterobactercloacae--97 +/- 3.0%, klebsiella 4.0 +/- 2.0%. enterobacter aerogenes, enterobacter hafnia, citrobacter, proteus rettgeri, proteus vulgaris were revealed in individual cases (0.2-1.0%). as a result of serological typing there were revealed 105 serological types of escherichia differing by 55 o-antigen variants, 26 h-ant ...1978747014
variation in urease activity of endemic hospital strains of proteus rettgeri and providencia stuartii.both urease-positive and urease-negative proteeae isolated from cross-infected patients in the same hospitals and, in three cases, from the same patients were examined for their biochemical reactions and somatic (o-) antigens. all isolates gave the same reactions in 17 biochemical tests and possessed o-antigens characteristic of providenic o-type strains 4 or 17. study of the isolates indicated that endemic strains are capable of undergoing variation in urease activity. in the current classifica ...1976789790
comparative activity of tobramycin and gentamicin against pseudomonas, proteus and providencia species.tobramycin is a new antibiotic resembling gentamicin. we measured the minimal inhibitory concentrations of these two antibiotics against five bacterial species that cause hospital-acquired infections and are resistant to many presently available antibiotics. the organisms tested were 500 strains of pseudomones aeruginosa, 100 strains of each of proteus rettgeri and pr. morganii, 50 strains of pr. vulgaris and 250 strains of providencia stuartii. tobramycin was 2 to 4 times more active than genta ...1975807310
[increased growth of chemotherapy-resistant hospital organisms through disinfection (author's transl)].in addition to determinants of resistance to chemtoherapy, a resistance plasmid of the hospital strain of prtoeus rettgeri from the munich hospital area also carries information on resistance to mercury ions. at the same time strains with this r-factor are more insensitive to phenylmercuric borate, the active principle of the widely used disinfectant merfer. this significance of the widely used disinfectant merfer. this significance of this resistance to disinfectants for the appearance of the l ...1976820967
intracellular crystalline deposits by bacteria grown in urine from a stone former.several species of bacteria were found to form an intracellular crystalline material when grown in urine obtained from a subject with a history of infrequent renal calculi formation. the following species: proteus mirabilis, proteus rettgeri, providencia stuartii, enterobacter aerogenes, enterobacter cloacae, escherichia coli, and candida albicans formed crystals of hydroxyapatite. klebsiella pneumoniae, pseudomonas aeruginosa, and proteus vulgaris produced crystals of calcite -ii. several of th ...1977844994
re: "nosocomial infection with highly resistant proteus rettgeri. report of an epidemic". 1977860710
treatment of hospita-acquired infections with amikacin.amikacin was used in the treatment of 56 serious gram-negative infections in 54 patients of whom 47 survived. in six of the seven nonsurvivors, the infections were under control at the time of death. the clinical isolates were multiple drug-resistant gram-negative organisms, with proteus rettgeri being most common. forty-five (80%) of these infections were nosocomial in origin, and the genitourinary tract was the source in 39 (70%). complications directly related to amikacin therapy were few and ...1977868903
[bacteriuria. bacteriological diagnosis and sensitivity to chemotherapeutic agents].in a brief introduction, methods for collecting urine and diagnosis criteria are reviewed. data relative to a study of about 10,000 samples of urine from patients admitted to various departments of the milan ca' granda hospital in 1975 are then reported. the frequencies of the various species of bacteria isolated in cases of bacteriuria are reported. those occurring most frequently were proteus (40.7%) of whose four species, proteus mirabilis and proteus rettgeri cover almost all cases, and esch ...1977869699
[nosocomial infections of the urinary tract by proteus rettgeri (author's transl)].out of urine samples from 170 male patients strains of the genus proteus with atypical biochemical characteristics and extensive corresponding multiresistance were isolated. their significance as causative agents in urinary tract infection looks to be established as well as their ability of transfer by cross infection. because of this we are concerned with the epidemiological occurrence of a special biotype of proteus rettgeri as a causative agent in urinary tract infections.1977914313
nosocomial infection with highly resistant, proteus rettgeri. report of an epidemic.over 22-1/2 months an epidemic of at least 127 cases of nosocomial infection developed from a strain of proteus rettgeri resistant to all antibiotics commonly tested in hospital laboratories. although there were at least four cases of septicemia and one related death, the majority of cases consisted of asymptomatic bacteriuria or clinically mild urinary tract infection. indwelling urinary tract devices and antibiotic therapy were important predisposing factors. data supported an association betw ...1976961694
[enterobacteria of reptiles (author's transl)].the aerobic gram-negative faecal flora of 78 reptiles consisting of 46 species (39 lizards of 23 species, 15 tortoises of 9 species, 24 snakes of 14 species) was studied. salmonella was found to be present in 50% of lizards, in 16% of tortoises and in 16% of snakes. there were all together 15 different serotypes. edwardsiella tarda was isolated in 20% of tortoises, in 12% of snakes but only in 3% of lizards. tortoises represent therefore the possible normal habitat of edwardsiella tarda. we isol ...1976998035
transferable gentamicin-tobramycin resistance in nosocomial strains of proteus rettgeri from oncologic patients. 19761015026
multidrug-resistant proteus rettgeri: an emerging problem.the recent development of multidrug-resistant strains of proteus rettgeri prompted a 6-year review of infections with this organism. ninety percent of infections involved the urinary tract. fifty percent of infections occurred on the neurology ward, where a progressive annual increase in attack rate was noted. statistically significant (p less than 0.005) increases in total length of hospitalization, length of hospitalization before infection, presence and duration of indwelling foley catheteriz ...19761047989
the tryptophanase from proteus rettgeri: sulfhydryl groups in the holo- and apo-enzyme preparations. 19751123078
the tryptophanase from proteus rettgeri, improved purification and properties of crystalline holotryptophanase.the inducible tryptophanase (l-tryptophan indole-lyase (deaminating) ec 4.1.99.1) was crystallized in holoenzyme from the cell extract of proteus rettgeri. the purification procedure included ammonium sulfate fractionation, heat treatment at 60 degrees c, deae-sephadex and hydroxylapatite column chromatographies. crystallization was performed by the addition of ammonium sulfate to the purified enzyme solution containing 20% (v/v) glycerol, 0.1 mm pyridoxal phosphate and 10 mm mercaptoethanol. th ...19751148216
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