ph changes on the surface of burns. 1975112
phospholipase d activity of gram-negative bacteria.a phospholipase hydrolyzing cardiolipin to phosphatidic acid and phosphatidyl glycerol was characterized in gram-negative bacteria but was absent in preparations of gram-positive bacteria, saccharomyces cerevisiae, and rat liver mitochondria. in cell-free extracts of escherichia coli, salmonella typhimurium, proteus vulgaris, and pseudomonase aeruginosa, this cardiolipin-hydrolyzing enzyme had similar ph and mg2+ requirements and displayed a specificity which excluded phosphatidyl glycerol and p ...1975360
profiles for ph, temperature, and dissolved o2 levels in enzyme production: monitoring in small-scale fermentors.the profiles thus established may be utilized for investigations of an organism's relationship to its microenvironment including metabolic shifts and pathways. areas of maximum respiratory activity, enzyme production, enzyme degradation, and attainment of the stationary phase are quite evident; however, duration and magnitude of the various phenomena may change with nutrient, temperature, and aeration efficiency. practical application of this simplified method would include: a) determination of ...19751123
microbiological study of gentamiycin.gentamycin prepared at the all-union research institute of antibiotics did not differ by its antibacterial spectrum and the activity level from gentamycin samples from other countries. by its activity against clinical strains of ps. aeruginosa gentamycin was somewhat inferior than polymyxin but much more superior than carbenicillin. an agar-diffusion method using bac. pumilus ntcc 8241 as the test microbe was developed for determination of gentamycin activity. the gentamycin sulfate complex and ...19752095
use of lincomycin, methicillin and ristomycin in the nutrient media for isolating pathogenic intestinal microorganisms.elective-differentiating solid nutrient media for simultaneous isolation of vibrioes, salmonella and shigella were developed. antibiotics active against grampostive microflora and dry bile salts inhibiting the growth of proteus were used as the inhibitors of the growth of the accompanying microflora. the medium was lincomycin and the bile salts may be prepared in a dry form.19752096
proceedings: inducible tetracycline resistance in r+ and r- strains of proteus mirabilis. 19752719
bactericidal activity and pharmacology of flucloxacillin.flucloxacillin, a recent addition to the group of isoxazolyl penicillins, was studied in vitro and in normal volunteers. the bactericidal activity of the drug against most strains of gram-positive bacteria including penicillin-resistant staphylococcus aureus was similar to that of oxacillin and approximately fourfold greater than that of cloxacillin. each of the three penicillins was administered orally to a group of ten volunteers for eight days in a dose of 500 mg four times a day. the mean co ...19763969
further observations on the potentiation of the antibacterial effect of methenamine by acetohydroxamic acid.the use of methenamine in the treatment of urinary tract infections due to proteus species is limited by urine alkalinity. acetohydroxamic acid, an inhibitor of urease, maintains acidity despite growth of proteus in urine. easily achievable concentrations of acetohydroxamic acid in vitro systems that simulated the dynamics of the urinary tract potentiated the antibacterial effect of methenamine against proteus species. the combined use of a urease inhibitor and methenamine may be effective in th ...19764573
studies of introital colonization in women with recurrent urinary infections. v. the inhibitory activity of normal vaginal fluid on proteus mirabilis and pseudomonas aeruginosa.normal vaginal fluid from premenopausal volunteers was inoculated with 10 strains of proteus mirabilis and 14 strains of pseudomonas aeruginosa at ph's of 4.3, 4.6 and 4.9. all bacteria were killed at ph 4.3. nine of 10 strains of proteus mirabilis and 12 of 14 pseudomonas aeruginosa were killed at ph 4.6. only 4 of 14 strains of pseudomonas aeruginosa were killed at ph 4.9, while 8 of 10 strains of proteus mirabilis were killed at the same ph. we conclude that in comparison to the common 0 grou ...19764631
bacteriological studies on cefatrizine (s-640 p) (author's transl). 19764635
gentamicin-susceptibility of various pathogens isolated from clinical materials.we studied on the antibacterial activity of gentamicin against various pathogens isolated from clinical materials mainly isolated during 1974 and 1975, comparing with other antibiotics. beta hemolytic streptococci, pneumococci and enterococci are less susceptible to gentamicin than staphylococci. staph, aureus and staph. epidermidis resistant to various antibiotics are very susceptible to gentamicin, and no resistant strain to this drug was found. haemophilus influenzae, h. parainfluenzae and h. ...19765619
comparative in vitro activity of cephalosporins.the in vitro activity of cephalexin, cephaloridine, cephalothin, cephapirin, cefoxitin, cephamycin c, cepharadine and cefazolin was determined against 443 isolates of bacteria. at a concentration of 12.5 mug/ml, all of the cephalosporins inhibited more than 60% of the isolates of klebsiella pneumoniae. at the same concentration, cephalexin, cephaloridine, cephalothin, cephapirin, cephamycin c and cefazolin inhibited more than 90% of isolates of proteus mirabilis. all of the cephalosporins except ...19766411
n-nitrosamine formation by cultures of several microorganisms.of 38 pure cultures of microorganisms tested, only one, pseudomonas stutzeri, was capable of forming dimethylnitrosamine from dimethylamine and nitrite during growth. resting cells of p. stutzeri, cryptococcus terreus, escherichia coli, and xanthomonas campestris formed dimethylnitrosamine, although no nitrosamine was found in growing cultures of the latter three organisms. no nitrosamine was produced by either growing cultures or resting-cell suspensions of pseudomonas fragi or proteus mirabili ...19767197
antibacterial activity of sisomicin in comparison with gentamicin.the antibacterial activity of sisomicin -- a new aminoglycoside antibiotic -- as compared with gentamicin was tested on 521 bacterial strains of different species in a serial-dilution test. staphylococci, streptococci, e. coli, klebsialla-enterobacter, indole-psitive proteus strains, pseufomonads, salmonads, salmonellae, and serratia marcescens were inhibited to the extent of 100% at a maximun of 4.0 mug/ml. sisomicin showed a higher antibacterial activity against part of the bacterial species. ...19769099
current resistence situation in a surgical and urological department.spectrum and sensitivity of bacteria were studied at the surgical (534 positive wound smears) and the urological clinics (7879 urine specimens). krankenhaus nordwest, frankfurt/m., during the period of 1969-1971 and in 1973. the most common organisms identified in wound smears were e. coli, followed by staph. areus, aerobacter and proteus species. e. coli were also predominant in urine, but followed by enterococci, proteus and pseudomonas. e. coli, proteus species and especially pseudomonas incr ...19769344
factors influencing the immune enhancement of intrapulmonary bactericidal mechanisms.the effect of specific immunization on the antibacterial defense mechanisms of the murine lung was assessed against streptococcus pneumoniae, staphylococcus aureus, staphylococcus aureus (smith), serratia marcescens, klebsiella pneumoniae, proteus mirabilis, and pseudomonas aeruginosa. immunization by aerosol inhalation significantly enhanced the intrapulmonary killing of pseudomonas aeruginosa and proteus mirabilis but not the remaining organisms. with p. mirabilis, systemic immunization induce ...19769364
microbiology of the female genital tract during pregnancy and parturition. 197610196
in vitro study of netilmicin compared with other aminoglycosides.netilmicin (sch 20569) is an ethyl derivative of gentamicin c(1a) that is active against most enterobacteriaceae, pseudomonas aeruginosa, and staphylococcus aureus isolates. among 342 clinical isolates tested, all staphylococci; 92% of escherichia coli, 93% of klebsiella pneumoniae, and 92% of enterobacter were inhibited by 0.8 mug or less of netilmicin per ml, but only 78% of p. aeruginosa were inhibited by 3.1 mug or less per ml. most clinical isolates of enterococci, serratia marcescens, and ...197610829
approach to a practical method for screening and identifying microorganism genera from urine (author's transl).in this study the author reported upon a practical new system for screening and identifying the microbial agents causing urinary tract infections. this system is composed of a combination of 3 screening procedures (ph-value + nitrite-test + catalase-test) and 8 selective culture media for the purpose of genus identification within 24 hours (uripret-g). a total of 130 cultures was investigated. the employed microorganisms were mainly recovered from urine samples. they included the following speci ...197611179
aerobic flora examination of sputum (author's transl).the routine bacteriological test of expectorate, except for mycobacteria, is usually unsatisfactory. there is a need of standardization which results in the present paper from a comparison between the data obtained by two different laboratories on the same samples. it is possible to achieve reasonable and uniform results establishing a uniformity of some procedures, namely; collection of specimens, homogenization, number and type of media, interpretation of data and so on.197613743
resistance to antibiotics of bacteria involved in respiratory infections (author's transl).the present status of resistance to antibiotics of bacteria involved in respiratory infections is reviewed. schematically it can outlined as follows. streptococcus b-haemolyticus as well as pneumococcus did not change their sensitivity to penicillin, but some strains are now resistant to tetracycline. streptococcus viridans, enterococcus and h. influenzae did not change substantially their sensitivity to antibiotics. staphylococcus aureus is the bacterial species that always poses some problems ...197613744
purification and properties of aldehyde dehydrogenase from proteus vulgaris.nadp-linked aldehyde dehydrogenase (aldehyde : nadp+ oxidoreductase, ec was purified from proteus vulgaris to the stage of homogeneity as judged by ultracentrifugation and polyacrylamide gel electrophoresis. the molecular weight of the purified enzyme was estimated to be 130000 by gel filtration. the enzyme which was crystallized from ammonium sulfate solution, lost its activity. the enzyme did not require coenzyme a, and the reaction was completely dependent on ammonium ions which coul ...197713839
which gentamicin assay method is the most practicable? 197714915
intestinal autoflora of the test subjects in a 6-month biological engineering experiment.during a 6-month bioengineering experiment the intestinal microflora of four test subjects was examined. changes in the composition of different groups of intestinal microflora (bifidobacteria, lactic-acid bacteria, sporogenous anaerobes, proteus, etc) were found. in spite of the unstable pattern of the intestinal microflora and its tendency for simplification, the total number of microorganisms in 1 g of feces remained relatively unchanged in all the test subjects.197715161
clinical characteristics of acute gastrointestinal diseases of proteus etiology in young children. 197715377
the bacteriology of skin cysts.thirty-nine clinically uninflamed cysts of the three most common varieties, epidermoid cysts, trichilemmal cysts and steatocystoma multiplex were removed under sterile conditions and the contents cultured under aerobic and anaerobic conditions. seventy-three percent of epidermoid cysts grew significant numbers of organisms whereas none of the trichilemmal cysts did so. the organisms found were the common skin commensals, staphylococcus epidermidis biotype i, anaerobic gram positive cocci of the ...197717428
azlocillin: in vitro studies of a new semisynthetic penicillin.the activity of azlocillin, a new semisynthetic penicillin, was determined against 582 clinical isolates of gram-negative bacilli and gram-positive cocci. over 75% of the isolates of pseudomonas aeruginosa were inhibited at a concentration of 12.5 mug or less per ml. azlocillin is also active against indole-negative and -positive proteus spp., inhibiting 98 and 71%, respectively, at a concentration of 12.5 mug or less per ml. isolates of klebsiella spp. and enterobacter spp. showed less suscepti ...197718083
differential susceptibility of escherichia coli and proteus mirabilis to mouse urine and to urea.the purpose of this investigation was to compare the antimicrobial properties of mouse urine and of urea against escherichia coli and proteus mirabilis. nornal urine was found to inhibit the growth of e. coli and p. mirabilis, whereas urine from diuresing animals permitted multiplication of these bacteria. addition of urea to urine from diuresing animals restored its bactericidal effect on p. mirabilis but not on e. coli. this bactericidal effect on p. mirabilis was dependent on the additive act ...197718546
contamination of rat urine with gut flora using all-glass metabolism cages for collection of urine and rat urine collected in all-glass metabolism cages, at least four strains of intestinal microflora were found: two types of e. coli, enterobacter cloaceae and proteus vulgaris. the number of bacteria of each strain increased with time. 2. the ph of the urine increased from 6-9 after 24 h to 8-95 after 120 h. the ph of the urine of neomycin-treated rats remained nearly constant over a period of two days. 3. nitroreductase activity was present in the rat urine. added p-nitrobenzoic acid was redu ...197718846
the self-assembly of synthetic filaments of myosin isolated from chaos carolinensis and amoeba proteus.synthetic myosin thick filaments were formed from preparations of electrophoretically homogeneous myosin isolated from chaos carolinensis and amoeba proteus when dialysed to physiological ionic strength and ph. myosin dialysed directly against low ionic strength buffers formed native-like thick filaments in the presence and absence of exogenous divalent cations. the average dimensions of the synthetic filaments grown under these conditions were 455 nm long and 16 nm wide with a distinct bare cen ...197719485
the effect of nutrient depletion on the drug resistance of a polymyxin-sensitive proteus mirabilis proceedings. 197722714
factors influencing the therapy of experimental proteus mirabilis meningitis in rabbits.the therapy of proteus mirabilis meningitis with gentamicin alone and in combination with chloramphenicol was studied in a rabbit model. antibiotics were administered for 8 hr. samples of serum and cerebrospinal fluid (csf) obtained simultaneously were assayed at 2-hr intervals for antibiotic concentration and counts of bacteria in csf. the percentage of penetration (concentration in csf divided by concentration in serum x 100%) of gentamicin ranged from 14% to 23%, but very large dosages were r ...197824668
purification of dna polymerase from proteus mirabilis. 197825512
modification of the ph-auxostat culture method for the mass cultivation of bacteria. 197826435
1-n hapa gentamicin b, a new aminoglycoside active against gentamicin resistant isolates--activity compared to other aminoglycosides.1-n hapa gentamicin b is a new aminoglycoside active against most enterobacteriaceae, pseudomonas aeruginosa and staphylococcus aureus. among 504 clinical isolates at a concentration of 12.5 microgram/ml all staph. aureus, escherichia coli, klebsiella, enterobacter, proteus rettgeri, providencia and 78% of pseudomonas, 86% of proteus morganii were inhibited. like other aminoglycosides, the activity was greatest at an alkaline ph and reduced by high cations concentrations. 1-n hapa gentamicin b w ...197827494
macrolide antibiotics m-4365 produced by micromonospora. iii. in vitro antimicrobial activity of antibiotic m-4365g2 (de-epoxy rosamicin).antibiotic m-4365g2 (de-epoxy rosamicin) produced by micromonospora capillata mcrl 0940 is a new basic 16-membered macrolide antibiotic with activity equal to or superior to erythromycin and josamycin against gram-positive bacteria. of interest are the high degree of activity against gram-negative bacilli and mycoplasmas, and striking inhibitory effects against indole-producing proteus spp. bactericidal activity of m-4365g2 is also to be noticed.197827495
piperacillin: in vitro evaluation.the in vitro activity of a new semisynthetic penicillin, piperacillin, was determined against 577 clinical isolates of gram-positive cocci and gram-negative bacilli. a concentration of 12.5 mug/ml inhibited 92% of isolates of pseudomonas aeruginosa, 82% of serratia marcescens, 73% of escherichia coli, 61% of klebsiella spp., and 42% of enterobacter spp. most proteus spp. were extremely susceptible; over 85% were inhibited by 0.10 mug/ml. piperacillin failed to inhibit the growth of gram-negative ...197828694
studies of relationship among terrestrial pseudomonas, alcaligenes, and enterobacteria by an immunological comparison of glutamine synthetase.antibody to purified glutamine synthetase from escherichia coli was prepared and used for an immunological comparison of glutamine synthetases from species of salmonella, citrobacter, enterobacter, serratia, proteus, erwinia, aeromonas, pseudomonas, acinetobacter, xanthomonas, alcaligenes, and paracoccus. the results of ouchterlony double diffusion experiments and quantitative microcomplement fixation studies indicated that the amino acid sequence of this enzyme was highly conserved in different ...197831146
opportunist lung infections. 197933268
purification and structure of a new nucleotide from proteus mirabilis that amplifies induction of tyrosine aminotransferase by glucocorticoid. 197934397
rapid screening for urease inhibitors.two methods are described that are suitable for the rapid screening of compounds as urease inhibitors. the first utilizes an electrode sensitive to nh4+ ions; the second is dependent on ph rise. a feature of both is a direct readout of reaction rate.197934578
[modern data on the antibiotic sensitivity of the microflora that is an etiological factor in ent diseases. ii. the antibiotic sensitivity of pneumococci, meningococci, influenza bacilli, klebsiella, enterobacteria, pseudomonas aeruginosa and proteus]. 197934945
[the bacterial flora of preputial space].the bacterial flora of the preputial space of 210 healthy males (43 children aged between 2 and 11 years, 137 males between 12 and 60 years and 30 men over 60 years) was determined by smears and cultueres from glans penis, sulcus coronarius and the adjacent prepuce. the results were grouped according to various criteria, e.g. glans covered or uncovered and age of males. differences in the distribution of germs could be found in relationship to age. in the case of an uncovered glans penis the pre ...197935486
[microflora of the maxillary sinuses in chronic sinusitis]. 197936723
intradermal responses to common bacterial antigens: influences of sex and clinical condition.intradermal responses to antigens of 12 common bacteria were evaluated in 218 dermatologic and 155 respiratory patients. women responded more frequently than men and respiratory patients responded significantly more frequently than dermatologic patients to certain antigens. interpretation of interspecies associations of responses suggested that certain organisms may be key species in the development of bacterial hypersensitivity.197937788
ps-5, a new beta-lactam antibiotic. ii. antimicrobial, a new beta-lactam antibiotic, has relatively potent antimicrobial activity against gram-positive and gram-negative bacteria, especially the enterobacter groups, serratia marcescens, the proteus groups and klebsiella pneumoniae. the activity of ps-5 against many beta-lactamase-producing organisms is greater than that of cefoxitin or cefazolin. ps-5 has good therapeutic activity in mice infected with staphylococcus aureus smith or enterobacter cloacae 45.197938238
ultraviolet irradiation disrupts somatic pili structure and function.three piliated bacterial species were exposed to ultraviolet light (7 x 10(3) microw/cm2), and the effect of increasing duration of irradiation on the integrity of the somatic pili was quantitated by negative-stain electron microscopy. heavily piliated proteus mirabilis became devoid of pili after 20 min of irradiation, but escherichia coli and neisseria gonorrhoeae required 40 min for complete depiliation. partially purified proteus pili underwent progressive loss of structural integrity with i ...197940875
anaerobic isolates in chronic recurrent suppurative otitis media. treatment with carbenicillin alone and in combination with gentamicin.tympanocentesis was performed in 32 pediatric patients with chronic recurrent suppurative otitis media. the aspirate was cultured aerobically and anaerobically. aerobes were isolated from ten patients (31.2%); anaerobes from one patient; and both aerobes and anaerobes from 21 patients (65.6%). there were 46 aerobic isolates. the aerobes commonly recovered were pseudomonas aeruginosa (24 isolates) proteus sp. (5) and staphylococcus aureus (3). there were 32 anaerobes isolated including anaerobic ...197941811
[photodynamic effect of quinacrine on bacteria].the acridine dye quinacrine (qa) was tested with regard to the photodynamic action on bacteria (proteus mirabilis, escherichia coli). the absorption maximum of the yellow dye qa ist in contrary to the photodynamically active dyes methylene blue (mb) and thiopyronine (tp) situated in the short wave region of the visible spectrum. using for illumination a common light source--they have in general a weak emission in the short wave region--relatively high concentrations of qa are necessary for photo ...197942229
microbiological activity of cefazedone as compared to cefazolin and a comparison of the antibacterial activity of (6r,7r)-7-(2-[3,5-dichloro-4-oxo-1(4h)-pyridyl]-acetamido)-3-([5-methyl-1,3,4-thiadiazol-2-yl)-thio]methyl)-8-oxo-5-thia-1-azabicyclo[4,2,0]oct-2-ene-2-carboxylic acid (cefazedone, refosporen) as compared to other cephalosporins it can be seen that cefazedone possesses good activity against gram-positive bacteria; as regards activity against enterobacteriaceae, in particular strains of e. coli, klebsiella species and proteus mirabilis, they fall w ...197939575
[acute hemorrhagic syndrome due to acquired deficiency of factors ii, vii and x. (considerations on a case)]. 197944762
[comparison of four recently introduced cephalosporins with respect to probability of resistance in multiresistant strains of escherichia coli, proteus mirabilis and klebsiella spec. (author's transl)].strains with the same number of resistances were arranged in so-called resistance classes. nine classes of resistance (0 to greater to or equal to 8) were formed by means of ten standard chemotherapeutics; the four new cephalosporins were excluded. for every resistance class frequency of cephalosporinresistance was described as coefficient ranging from 0 to 1 (fig. 1). in cephalothin the coefficients were markedly rising only in 6 (7)-fold resistant strains of the species examined. similar but s ...197944785
[the distribution of minimal inhibitory concentrations of recently introduced cephalosporins in multiresistant strains of escherichia coli, proteus mirabilis and klebsiella spec. as revealed by zone sizes of a standardized agar diffusion test (author's transl)].strains of a species were divided into two groups according to the number of resistances (less than or equal to 4, greater than or equal to 5) using 10 standard chemotherapeutics regularly examined, the new cephalosporins not being among them. these groups of less than or equal to 4- and greater than or equal to 5-fold resistant strains were compared for each cephalosporin tested (fig. 1). the most different distributions of zone diameters (of both groups) were seen in cephalothin, whereas in ce ...197944786
incompatibility of r plasmids from clinical material.thirteen r plasmids derived from strains of e enterobacteriaceae isolated from clinical material have been characterized. they belonged to many incompatibility groups and differ widely respecting other phenotypic characteristics, even if they come from bacteria isolated from a small geographic area.197944944
in vitro aggregations in solutions simulating urine. 197936868
[antibiotic treatment in acute peritonitis].the selection depends on several factors and in particular: -the means of transport by which the antibiotic reaches the peritoneum : the aminosides and the betalactamines attain the peritoneum easily while the polymyxins do not; -the causative agent: most often it is a gram negative aerobic or anaerobic bacteria. the entero-bacteria predominate but in the last few years bacteroides fragilis has been frequently encountered giving rise to numerous studies. the flora is most often polymicrobic. th ...197835071
protection against experimental proteus mirabilis pyelonephritis in rats and significance of immunity.intraperitoneal immunization with formalin-killed bacteria as well as previous hematogenous infection with proteus o3h1 showed a protective effect against hematogenous pyelonephritis in rats when the homologous strain was used. transfer of hyperimmune antisera protected against hematogenously induced infection. neither intravesical or intraperitoneal immunization with formalin-killed bacteria nor transfer of urines containing antibodies of the igg class protected against ascending pyelonephritis ...197831056
the antimicrobial activity of urine of paraplegic patients receiving methenamine mandelate.the antimicrobial activity of urine collected from adult male paraplegics ingesting methenamine mandelate (mm) was evaluated. the in vitro bacterial growth in urine from these patients was inhibited when the free formaldehyde (hcho) concentration was 10 to 22 microgram per ml. when the hcho concentration was in the region of 28 microgram per ml or greater, bactericidal effect became apparent. urine containing 1323 microgram of mm per ml with a ph of 5.9 when freshly voided had sufficient hcho to ...197830734
[use of the preparation "progress" for the inhibition of the rate of growth of proteus on levin's medium]. 197548604
letter: antagonism of oxolinic acid by nitrofurantoin. 197548654
infection caused by proteus mirabilis strains with transferrable gentamicin-resistance factors.during a period of 10 weeks, four patients in one hospital became infected with gentamicin-resistant proteus mirabilis. in two of them septicaemia associated with indwelling catheters developed, one had urinary tract and wound infections, and in the fourth patient the organism was isolated from a superficial wound. the p. mirabilis strains showed multiple drug resistance. strains form the first three patients were apparently identical and were sensitive to tobramycin. their gentamicin resistance ...197548945
localization of d-amino acid oxidase on the cell surface of human polymorphonuclear leukocytes.the ultrastructural localization of d-amino acid oxidase (dao) was studied cytochemically by detecting sites of hydrogen peroxide production in human polymorphonuclear leukocytes (pmns). reaction product, which forms when cerous ions react with h2o2 to form an electron-dense precipitate, was demonstrated on the cell surface and within the phagosomes of phagocytically stimulated cells when d-amino acids were provided as substrate. resting cells showed only slight activity. the competitive inhibit ...197826690
micrococcal urinary-tract infections in young a prospective study in young women, novobiocin-resistant subgroup-3 micrococci were the second commonest cause, after escherichia coli; of acute urinary infections. proteus mirabilis was the only other causative organism. symptoms, pyuria, or possible aetiological factors were the same in micrococcal and coliform infections. the infecting micrococcus "biotype" was only rarely found among the normal flora of the genitourinary tract of young women, though other micrococci and staphylococci were ...197551404
[bacteriological studies of butirosin sulfate, a new aminoglycoside antibiotic (author's transl)]. 197551941
[significance of some immunobiological indices in acute purulent destructive pneumonia in children]. 197552231
a preliminary study of butirosin in the treatment of susceptible bacterial infections. 197552659
[use of a furagin medium for isolating pseudomonas pyocyanea]. 197552751
the immunotropic effect of cysteine in the foetal period and in adult rats after administration of thymus-independent antigens. 197725698
letter: providencia stuartii infections. 197553535
practice laboratory bacteriology. 197553936
significance of microbial contamination of stored cadaver kidneys.the importance of microbial contamination of cadaver kidneys was assessed in 83 consecutively stored and transplanted kidneys. fourteen kidneys had a single positive culture during storage and five had multiple positive cultures. only one postoperative infection could be traced to kidney contamination during storage (candida wound infection). in three of 64 patients who received noncontaminated kidneys, posttransplant wound infections developed. no wound infections occurred in 35 patients who re ...197825059
[method of bacteriologic diagnosis of proteus in intestinal infections in children]. 197554497
evaluation of renal acidification in patients with urea-splitting organisms. 197824020
diminished effect of gentamicin under anaerobic or hypercapnic conditions.the in-vitro activity of gentamicin, judged by m.i.c. determinations, was much reduced when a normal aerobic atmosphere was replaced either by air +4% co2 or by anaerobic conditions. the phenomenon was greatest for staphylococcus aureus, where a decrease in activity of up to 20-fold was found. for escherichia coli, klebsiella aerogenes, enterobacter spp., and proteus spp. the factor of decrease was between 15-fold and 2-5-fold. changes in medium ph, as a result of bacterial growth, can explain t ...197655718
[serological activity of different antigenic preparations of proteus in precipitation tests]. 197555948
the effect of temperature on the motility and viability of specimens of semen kept at 37 degrees c sperm lose their motility and viability. if kept at 4 degrees c they retain their viability but lose their motility from so-called thermal shock. the best temperature to keep semen in order to preserve sperm motility is 20 degrees c. loss of motility at 37 degrees c is not entirely prevented by prevention of bacterial contamination with antibiotics.197723196
the contractile basis of amoeboid movement iii. structure and dynamics of motile extracts and membrane fragments from dictyostelium discoideum and amoeba proteus.motile extracts from d, discoideum and a. proteus have been characterized in order to compare the structural dynamics and chemical regulation of movement in 2 different types of amoeboid cells. the structural dynamics of both extracts involve the formation of a nonmotile cytoskeleton followed by the contraction of actin and myosin to generate both direct contractile force and cytoplasmic streaming. the contractions are regulated by calcium ions and a threshold of ca. 1.0 x 10(-6) m calcium induc ...197722087
letter: therapeutic use of peritoneal cells. 197658290
a new factor from enteric bacteria of rats amplifying induction of liver enzyme by glucocorticoid. 2. mechanism of action.1. an amplifier of the action of glucocorticoid was purified from proteus mirabilis as described previously. it was found that it amplified the induction of liver tyrosine aminotransferase by dexamethasone markedly with doses of dexamethasone that caused minimal enzyme induction, but had little effect with doses that caused maximal induction. thus the amplification may represent a saving of glucocorticoid. the amplification of enzyme activity was brought about by increase in amount of enzyme. 2. ...197721084
antigenic relationship between morganella morganii and yersinia enterocolitica.two new o antigens have been described for the morganella morganii antigenic schema. o antigens of the strains representing the new serotypes (o43 :h2 and o44 : h19, 37) are related to yersinia enterocolitica o9 and o17, respectively.197659520
immunochemical study of the peptidoglycan of gram-negative bacteria.the specificity of antibodies directed against the peptidoglycan of gram-negative bacteria was studied. the peptidoglycans of proteus vulgaris, escherichia coli, moraxella glucidolytica, neisseria perflava, give identical precipitin reactions. by means of inhibition studies with various peptidoglycan subunits and synthetic peptides, it was shown that the antibodies are essentially directed against the peptide moiety of the peptidoglycan: l-ala-d-glu (l)-mesoa2pm-(l)-d-ala, that the peptide react ...197660233
a new factor from enteric bacteria of rats amplifying induction of liver enzyme by glucocorticoid. 1. purification, properties and biological action.1. a factor, which amplifies the inductions of several liver enzymes by glucocorticoid, was partially purified from proteus mirabilis from rat intestine. the factor (amplifier) was completely inactivated by alpha-glucosidase, but not by other glycoside hydrolases, proteases, nucleases or phosphatases tested; it was also hydrolysed by hcl with liberation of reducing sugars. thus the oligosaccharide in this factor seems to be essential for the amplification. 2. in adrenalectomized rats the amplifi ...197721083
"5-amino-5"-deoxybutirosin, a semisynthetic analogue of butirosin a: antibacterial activity in vitro and in mice.aminodeoxybutirosin (ad-btn), the 5''-amino-5''-deoxy derivative of butirosin (btn), was synthesized to improve on the antibacterial activity of btn by preventing bacterial enzymatic phosphorylation at the 5'' position. ad-btn possesses the spectrum characteristic of btn and gentamicin (gtm) and was active at low levels in vitro against a wide variety of gram-negative species including pseudomonas aeruginosa, indole-positive proteus and serratia marcescens; its action was bactericidal against bo ...197662554
inhibition of bacterial agmatinase by substrate analogs.activity of agmatinase (ec from proteus vulgaris was studied in presence of guanidine derivatives of agmatine as substrates. the guanidine derivatives, containing carboxyl group, did not interact with the enzyme. an inhibitory effect developed if the carboxyl group was esterified. for exhibition of the effect the length of hydrocarbon radical in ligand and presence of hydrophobic groups were important. one of the most effective inhibitor was n-isoamylene agmatine (k1=0.001 m). compound ...197617224
[the effect of ear surgery to the immunologic defense system of the middle ear during chronic otitis media (author's transl)].alpha-1-antitrypsin and alpha-2-macroglobuline are very important proteinase inhibitors for the healing process in chronic otitis media, because they can inhibit numerous bacterial and leukocytic proteinases: alpha-2-macroglobuline can block the malignant proteinases of pseudomonas aeruginosa, staphylococcus aureus and proteus vulgaris. in 58 cases in the middle ear secretion was examined and the level of alpha-1-antitrypsin and alpha-2-macroglobulin investigated pre- and postoperatively. by the ...197663098
[effect of levoristatin on intestinal autoflora following oral administration]. 197664919
[experimental infection of domestic animals with r. prowazeki and r. canada].the authors infected lambs with r. prowazeki and r. canada to ascertain their possible role in the natural infection of the animals. the lambs were infected subcutaneously with increasing doses; rickettsiemia was recorded with the aid of tests on guinea pigs and ixodidae and argasidae ticks fed on the lambs. dynamics of antibody formation was ascertained in the infected animals in the agglutination reaction and in the complement fixation test. the antigenic affinity of r. canada and rickettsia o ...197665076
[giant urinary bladder calculi in patients with pseudomonas aeruginosa and proteus vulgaris infections following prostatectomy for prostatic adenoma]. 197768625
intracellular nucleodepolymerase of bacteria, representatives of the proteus and providencia groups. its isolation and properties.high activity of enzymes, splitting native, denaturated dna, deoxyribooligonucleotides and rna, was observed in cell free extracts of bacteria--representatives of 5 strains of proteus-providencia. some properties of nucleases were studied in cell free extracts. in the bacteria studied dnaases were thermolabile proteins, which were completely inactivated at 50-60 degrees, rnaases were more thermostable. the ph optima of the dnaases were at ph 9.0-11.0 in cell free system; rnaases were maximally a ...197617219
a polyvalent human gamma-globulin immune to pseudomonas aeruginosa: passive protection of mice against lethal a means to development of guidelines for therapeutic application to human disease, preparations of human polyvalent gamma-globulin immune to pseudomonas aeruginosa (pg) were studied in acute infections in mice. pg was highly effective in controlling lethal infections induced in mice by the major immunotypes of p. aeruginosa; greater than or equal to 10 microgram of of gamma-globulin per mouse protected against challenge with less than or equal to 10(6) 50% lethal doses of p. aeruginosa. pg wa ...197770492
inhibition of phagocytosis in vitro by obligate anaerobes.a variety of species of obligate anaerobes have been shown to interfere with the phagocytosis and killing of proteus mirabilis and other aerobic bacteria in vitro. although all the obligate anaerobes examined showed this activity, the effect was greatest with strains of bacteroides melaninogenicus and b. fragilis. in contrast, none of the 36 aerobes tested acted in this way. these observations suggest that the presence of obligate anaerobes may be fundamental to the pathogenesis of some types of ...197773952
specific and cross-reactive activation of rabbit peripheral blood lymphocytes by streptococcal vaccines.the ability of primed rabbit blood lymphocytes to respond in vitro to the homologous streptococcal group antigen depends on its presence in culture in the form of vaccine or cell walls thereof. these lymphocytes can also be stimulated in vitro by streptococcal vaccines with chemically related group antigens. the basis for this cross-stimulation apparently resides in shared rhamnose moieties. activation of these lymphocytes was not achieved by vaccines from unrelated bacteria. there is also the s ...197874347
mucocutaneous lymph-node syndrome with positive weil-felix reaction but negative leptospira studies. 197876261
prospective study of the treatment of septic shock.a study of 113 patients with septic shock admitted to an intensive therapy unit (i.t.u.) during a 3-year period showed that a significant reduction in mortality was achieved after the introduction of a treatment programme which included early intermittent positive-pressure ventilation and aggressive surgery in addition to conventional management with fluids, oxygen, and antibiotics. vasoactive drugs played an important but not essential role in therapy.197877955
synthetic disaccharide-protein antigen for production of specific o2 antiserum for immunofluorescence diagnosis of salmonella.antisera from rabbits immunized with the synthetic disaccharide paratose 1 leads to alpha 3 mannose, representive of salmonella o-antigen 2, covalently linked to bovine serum albumin (bsa), were used in indirect immunofluorescence studies for the identification of salmonella serogroup a (o-antigen 1,2,12) bacteria. among 1311 enteric bacteria tested, 497 were salmonella. the anti-paratose 1 leads to alpha 3 mannose-bsa serum identified correctly all the 63 serogroup a strains tested. no positive ...197878659
[dry medium with ampholan for isolation of proteus and providencia]. 197879680
intercontinental nosocomial infections. 197879961
stomach as source of bacteria colonising respiratory tract during artificial ventilation.10 adults had intermittent positive-pressure ventilation for 3--34 days. all 10 had paralytic ileus. microbial overgrowth in the stomach was found in 9 patients (bacterial in 7 and fungal in 2); gram-negative bacteria predominated. the trachea invariably became colonised by bacteria, mainly gram-negative organisms. in 3 instances the gram-negative bacteria were found in the stomach before they appeared in the tracheal aspirate, and in 1 case the pathogen originated in the faeces.197881991
effect of organic mercurials and sulfhydryl compounds on the urease activity of proteus: inhibition by urine and ascorbic acid.meralluride, mercaptomerin, ethacrynic acid, and penicillamine inhibited urease activity of proteus mirabilis. the activity of the organic mercurials and ethacrynic acid was markedly inhibited by human and dog urine. antiurease activity could not be detected in the urine of a human and a dog given meralluride by injection. urine from patients receiving penicillamine also failed to inhibit urease activity. ascorbic acid inhibited, whereas dehydroascorbic acid enhanced, the activity of the mercuri ...197610828
urinary beta 2 microglobulin in upper and lower urinary-tract infections.beta 2-- microglobulin excretion in 24 h urine collections and beta2- microglobulin clearance were significantly increased in patients with upper-urinary-tract infections, but beta 2- microglobulin clearance and excretion were normal in patients with cystitis. beta 2-microglobulin estimation may be used to distinguish between upper and lower urinary-tract infections, except when pre-existing tubular damage is present. voided urine must have a ph above 6 . 0, since beta 2- microglobulin is rapidl ...197986044
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