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some observations on the effects produced in white mice following the injection of certain suspensions of corroding bacilli.strictly anaerobic and facultatively anaerobic strains of "corroding bacilli" failed to produce any pathological symptoms when injected into white mice and no viable organisms could be recovered after 7 days. however, when these same strains were coupled with certain other living bacteria or certain sterile bacterial extracts, lesions developed from which corroding bacilli could be isolated even after 21 days.19751080
human bite infections. 197773987
abscesses of the frontal lobe of the brain secondary to covert dental sepsis.the bacterial species found in pus aspirated from brain abscesses in two patients were typical of those found in dental sepsis. subsequently apical-root abscesses were demonstrated in the upper jaws of both patients. this evidence strongly suggests that these cerebral abscesses were secondary to dental sepsis which could have spread from the teeth to the frontal lobes by several possible antaomical pathways.197879867
histopathology of periodontal disease in gnotobiotic rats monoinfected with eikenella corrodens. 1978148502
biological activity of the slime and endotoxin of the periodontopathic organism eikenella corrodens.a partially purified water-soluble slime extract was obtained from two strains of the oral pathogen eikenella corrodens, designated cs10 a and cs10 b. endotoxin was also isolated from this organism by the phenol-water extraction procedure. assays including the local shwartzman skin reactivity, chicken embryo lethality, limulus lysate clotting, spleen cell mitogenicity, and immune adjuvancy were used to test the biological properties of these two bacterial extracts. in each of these assay systems ...1979161911
[eikenella corrodens infection of a branchial cyst]. 1977196344
the effect of nalidixic acid on microaerophilic and anaerobic bacteria. special study of clostridia.study of the sensitivity of 141 strains of anaerobic and microaerophilic bacteria to nalidixic acid shows that few bacteria are inhibited by low concentrations (veillonella, eikenella, most of the clostridia). nalidixic acid appears to be bactericidal with respect to clostridium perfringens, and its point of attack in the dna is probably different from that of metronidazole.1979232341
a study of the bacteria associated with advancing periodontitis in man.samples of apical plaque were taken by means of an anaerobic gas-flushed syringe from 21 sites in eight patients. the samples were anaerobically dispersed, diluted and plated and incubated in an atmosphere of 80% n2, 10% h2 and 10% co2 for 7-21 days. all colonies on plates containing 20-50 isolates were picked, repeatedly restreaked, characterized and identified where possible by a probabilistic computer identification program. the sites were divided into four groups on the basis of clinical fea ...1979294457
[polymicrobial septicemia caused by strictly anaerobic bacteria]. 1977322091
[report of a case of subcutaneous abscess due to eikenella corrodens in a splenectomized patient (author's transl)].a case of subcutaneous abscess of the chest-wall due to eikenella corrodens is reported in a patient recently splenectomized. this bacillus was grown in pure culture. processing specimens and identification methods of this little gram-negative bacillus are described. eikenella corrodens is a commensal frequently encountered in mucous membrane surfaces. it is likely that this microorganism may be an "opportunist" pathogen.1977327407
liver abscess: eikenella corrodens and streptococci. 1977328797
eikenella corrodens isolated in oral infections of dental origin.eikenella corrodens causes significant clinical infection more frequently than is suspected at the present time. the laboratory must be made aware of the organism and the techniques that are necessary to identify it. the clinician must be aware of the methods of isolating organisms in general. the use of a transport solution was shown to be a highly effective and clinically practical way of isolating those organisms present. the pathogenic potential of e. corrodens can no longer be doubted.1977329171
microbiology problem. 1977329675
isolation of bacteroides corrodens and eikenella corrodens from human clinical specimens. comparative study of incidence and methods of identification.in the course of a systematic search for bacteroides corrodents and eikenella corrodens in clinical specimens submitted for microbiological analysis, 61% of the specimens from anal abscesses, 6% of the vaginal specimens and none of the pharyngeal specimens yielded b. corrodens, whereas e. corrodens was recovered from only 9% of the pharyngeal specimens. some characteristics were found to be useful in differentiating between the two species: b. corrodens strains were strictly anaerobic, cytochrom ...1977334672
[bacteriological study on eikenella corrodens isolated from pulmonary puncture fluid of lung abscess (author's transl)]. 1977335121
eikenella corrodens subacute bacterial endocarditis: mixed infection in amphetamine user. 1977340988
role of bacterial products in periodontitis: immune response in gnotobiotic rats monoinfected with eikenella corrodens.the development of humoral and cell-mediated immune responses to eikenella corrodens (a bacterium that causes periodontal lesions in gnotobiotic rats) was measured and compared with the rate of appearance of macroscopic lesions. a possible inverse relationship was found. a strong cell-mediated immune response, as measured by skin reactivity and lymphocyte mitogenesis, occurred between 4 and 6 weeks after infection and subsided soon thereafter to a low response level. humoral antibodies to endoto ...1978342412
eikenella osteomyelitis of the mandible associated with anemia of chronic disease.an unusual case of mixed bacterial osteomyelitis has been reported. the prodominant organism, e corrodens, normally is an inhabitant of the aerodigestive tract; its pathogenicity should not be overlooked in the diagnosis and treatment of oral infections. in addition, descriptions of anemia of chronic disease and of the spontaneous healing of a large defect of the bone have been presented.1978344842
recurrent meningitis and brain abscess caused by eikenella corrodens.a case of recurrent menigitis and brain abscess caused by eikenella corrodens in a patient with previous otitis media and mastoidectomy.1978353768
sinus infection due to eikenella corrodens.eikenella corrodens is a gram-negative rod that has been identified as a cause of endocarditis, osteomyelitis, pneumonia, cellulitis, and other infections. because it is difficult to grow unless it is incubated in 10% carbon dioxide and because it may be overgrown by other organisms, it can be overlooked as a sinus pathogen. this is a report of the isolation of e corrodens from the sinuses of three patients with sinusitis. three important features of infection with e corrodens, which are illustr ...1978354619
infections following clenched-fist injury: a new perspective.fifteen cases of clenched-fist injury were studied by aerobic, anaerobic, and 10% co2 cultures. anaerobic bacteria and eikenella corrodens were prominent pathogens, being recovered in 60% and 20% of cases, respectively. these organisms are more susceptible to penicillin than to penicillinase-resistant penicillins or cephalosporins. all clenched-fist injuries should be cultured in aerobic, anaerobic, and 10% co2 atmospheres. we recommend the use of both penicillin and a penicillinase-resistant pe ...1978359634
susceptibility of eikenella corrodens to ten cephalosporins.the susceptibility of 24 strains of eikenella corrodens was determined, by the agar dilution technique, to 10 cephalosporins, as well as to clindamycin, penicillin and dicloxacillin. all strains were uniformly very susceptible to penicillin g and cefoxitin and resistant to clindamycin and dicloxacillin. cefazolin showed good activity. cephalexin, cephradine, and cefadroxil showed poor activity, and cefamandole's activity was relatively poor. cephalothin, cephapirin, cefaclor, and cephaloridine s ...1978363054
selective medium for isolation of eikenella corrodens from periodontal lesions.the addition of 5 microgram of clindamycin per ml to a modified todd-hewitt growth medium permitted the ready enumeration of eikenella corrodens from deep periodontal lesions because it allowed differential growth amongst the periodontal pocket gram-negative microaerophilic-anaerobic flora, maximized the numbers of e. corrodens in such culture, and inhibited the growth of most of the other confounding microorganisms.1978363744
eikenella corrodens in human bites.eikenella corrodens, a gram negative rod, was cultured in about one third of 24 patients with human bite wounds. the organism was sensitive to penicillin but not to methicillin. clinically the infections in which eikenella corrodens were found were not different from other infections. because of the variety of possible pathogens in human bite infections, we start the patients on a broad spectrum antibiotic while awaiting the results of the culture and sensitivity. however, antibiotics alone are ...1978365416
role of bacterial products in periodontitis: humoral immune response to eikenella corrodens.eikenella corrodens can induce periodontitis-like disease in gnotobiotic rats. some components of this bacterial cell elicit measurable humoral immune response during the development of the disease, but in this system endotoxin is not among the efficient immunogens. because no humoral immune response could be seen to the endotoxin of eikenella corrodens it is assumed that this endotoxin can act uncontrolled in monoinfected rats. accordingly, the lack of protective humoral immune response to path ...1978365757
isolation of eikenella corrodens from pulmonary infections.eikenella corrodens is a capnophilic gram-negative rod that is part of the normal human oral flora. we report the isolation of e. corrodens by transtracheal aspiration or percutaneous aspiration from 7 patients with pneumonia and/or lung abscess. four of the 7 patients had an associated carcinoma of the lung. the susceptibilities of strains were tested to penicillin, dicloxacillin, clindamycin, and 10 cephalosporins. all strains were very susceptible to penicillin and cefoxitin and resistant to ...1979369416
eikenella corrodens: a new pathogen.oral infections that result from trauma or dental manipulation are often thought to be of minor importance to the practicing clinician. the majority of oral infections respond well to treathis form of simple therapy is no longer as efficacious as it has been though to be. soment with the common antibiotics without the need for laboratory culture and sensitivity. there are instances, becoming increasingly frequent, when this form of simple therapy is no longer as efficacious as it has been though ...1979375152
eikenella corrodens as pathogen. 1979375798
experimental eikenella corrodens endocarditis in rabbits.the ability of eikenella corrodens to cause endocarditis in catheterized rabbits was studied. e. corrodens 1073, the serum-resistant strain used in the study, was isolated from a human periodontitis lesion. thirty-four rabbits, surgically catheterized across the aortic valve and injected intravenously 24 to 48 h later with 10(7) to 10(9) log-phase organisms, were studied. only three rabbits developed positive blood cultures and only two rabbits died before the time of sacrifice at 14 days after ...1979378835
eikenella corrodens and pulmonary infections. 1979380422
deep fasciitis of the biceps region.an infection of the biceps fascia, later myositis, and spreading to the pectoralis is described in six patients. the majority were synergistic infections with an anaerobic peptococcus, eikenella, or bacteroides and an aerobic streptococcus. five of the patients were drug abusers. excision of the biceps and portions of the pectoralis major was necessary in four patients.1979381370
eikenella corrodents infection of the hand.the clinical presentation and course of two patients with eikenella corrodens infection of the hand is recorded. this recently recognised organism must not be regarded as a harmless commensal and should be differentiated from the bacteroides group because of its resistance to clindamycin. radical surgical debridement is the most important aspect of therapy.1979385463
septicemia and pleural effusion from eikenella corrodens, a normal inhabitant. 1979388177
an unusual organism causing orbital cellulitis.bacterial orbital cellulitis is a feared complication of paranasal sinus infection. staphylococcus and streptococcus species are the commoner pathogens involved in these cases. however, anaerobic bacteria and unusual gram-negative organisms should be suspected as well. we treated a case of bacterial orbital cellulitis due to foci of infected paranasal sinuses caused by eikenella corrodens, a gram-negative rod. the patient was managed with intensive antibiotic coverage and surgical intervention.1979389281
septicemia and pleural effusion from eikenella corrodens, a normal mouth inhabitant. 1979390358
eikenella corrodens: a pathogen in head and neck infections.e. corrodens as a co-existent or primary causal agent in six cases of osteomyelitis or orofacial infections following trauma or elective dental extraction is presented. the importance of this facultative gram-negative bacillus as a head and neck pathogen is discussed.1979390466
biological activity of lipopolysaccharides isolated from bacteria in human periodontal lesions. 1979398754
periorbital, subgaleal, and epidural empyema secondary to eikenella sinusitis. 1979499026
medium for selective isolation of fusobacterium nucleatum from human periodontal pockets.a selective medium, cve agar, was developed for the isolation of fusobacterium nucleatum from subgingival plaque of periodontally diseased patients. the medium contained 1.0% trypticase (bbl microbiology systems), 0.5% yeast extract, 0.5% nacl, 0.2% glucose, 0.02% l-tryptophan, 1.5% agar, and 5% defibrinated whole sheep blood. erythromycin and crystal violet were added as the selective inhibitory agents at concentrations of 4 and 5 micrograms/ml, respectively. the medium permitted almost total r ...1979521483
haemophilus aphrophilus cholecystitis.cultures from the gallbladder and blood of a 60-year-old man with acute cholecystitis grew haemophilus aphrophilus. this organism, an unusual isolate in clinical specimens, is most frequently seen in patients with either endocarditis or brain abscesses. haemophilus aphrophilus may be distinguished from eikenella corrodens and actinobacillus actinomycetemcomitans on the basis of colonial morphology and the biochemical tests for oxidase and catalase production and fermentation of lactose, sucrose, ...1978637050
case report. cardiobacterium hominis: review of prior infections and report of endocarditis on a fascia lata prosthetic heart valve.the clinical spectrum of disease caused by cardiobacterium hominis, a small, gram-negative coccobacillus, is little known to physicians. from analysis of a new case of c hominis endocarditis on a fascia lata aortic valve, and from review of all previous reports of infection due to this microorganism, a remarkably consistent clinical picture emerged. c hominis only causes endocarditis, affects middle-aged individuals with structurally abnormal, left-sided cardiac valves, and follows a subacute co ...1978727215
central nervous system infection with eikenella corrodens: report of two cases.two cases of central nervous system infections from which e. corrodens has been isolated are reported. the portals of entry, clinical course, and antimicrobial responses conform to other reports in the literature. the importance of obtaining careful anaerobic cultures is emphasized.1976765945
eikenella corrodens found in root canal system of human tooth. 1976768403
clinical isolates of anaerobic gram-negative rods with a formate-fumarate energy metabolism: bacteroides corrodens, vibrio succionogenes, and unidentified strains.strains of anaerobic, gram-negative bacteria, isolated from human clinical specimens and from studies of human normal flora, that have energy metabolism similar to vibrio succinogenes are described. included are four human isolates of v. succinogenes, five similar strains of motile straight rods, three strains of bacteroides corrodens, and two unidentified strains. all strains studied grew poorly in usual anaerobic broth media but produced good turbidity in overnight broth cultures in media cont ...1976770499
current taxonomy and identification of nonfermentative gram negative bacilli.in recent years significant advances have been made in the characterization and taxonomy of nonfermentative bacilli as well as in the recognition of their pathogenic potential for man. in addition, certain other infrequently isolated bacteria that may be fermentative have been recognized, and improved methods for their identification have been developed. this discussion attempts to present a practical approach to the identification of these micro-organisms in the clinical microbiology laboratory ...1976773809
eikenella corrodens comes of age. 1976775649
eikenella corrodens osteomyelitis, arthritis, and cellulitis of the hand.eikenella corrodens was isolated from an orally contaminated hand wound which resulted in cellulitis, osteomyelitis, and arthritis. e corrodens is a gram-negative, microaerophilic bacillus which only lately has received attention as a possible pathogen. the organism grows characteristically as small, corroding, or pitting colonies on blood agar. it typically requires hemin or blood for reliable aerobic growth. oral contamination of wounds predisposes to infection with e. corrodens. the managemen ...1976775650
a trichomonas species in a mixed microbial meningitis. 1976787565
pancreatic abscess with haemophilus influenzae and eikenella corrodens.an infected pancreatic pseudocyst was caused in part by haemophilus influenzae and eikenella corrodens. to my knowledge, neither organism has been isolated previously from pancreatic abscesses. i believe that the infecting bacteria originated in the oropharynx and descended through the duodenum.1976789926
[pathogenic role of various pleomorphic gram-negative bacteria]. 1976796897
butandioldehydrogenase in eikenella corrodens and related bacteria.the butandioldehydrogenase was examined in 153 strains of eikenella, moraxella, acinetobacter, agrobacterium, haemophilus, actinobacillus, pasteurella, cardiobacterium and "tm-1" of hollis et al. this enzyme has been proved to be useful in the differentiation of this group of bacteria.1976797181
initial colonization of teeth in monkeys as related to diet.the initial phases of plaque development on nonretentive tooth surfaces were studied bacteriologically in macaca irus monkeys fed by stomach tube and provided with various oral supplements. except for the oral implantation of streptococcus mutans in some of the animals, the oral flora was not changed prior to the studies. dental plaque was allowed to develop on initially cleaned tooth surfaces for 3 to 5 h. plaque samples were collected and cultured on a number of selective and nonselective agar ...1976825462
tobramycin and cephalothin for treatment of suspected sepsis in neutropenic children with cancer.the safety and efficacy of tobramycin and cephalothin in treatment of suspected sepsis were studied in neutropenic children with various malignancies. twenty episodes of suspected sepsis in 19 febrile children with cancer were treated with parenteral tobramycin and cephalothin; the duration of therapy ranged from one to 80 days. in 14 of the 20 episodes of suspected sepsis, a favorable clinical response was achieved within five days after initiation of antibiotic therapy. these episodes included ...1976972278
[the demonstration of twitching motility in eikenella corrodens].in 18 out of 39 strains of e. corrodens twitching motility was observed. spreading colonies were associated with this kind of motility.19751092994
letter: arthritis due to eikenella corrodens. 19751100797
eikenella corrodens: a clinical problem.e corrodens occurs as a significant clinical infection more frequently than suspected or cultured at the present time. it is essential that the dentist or physician work closely with the laboratory clinician in order to use proper techniques for its isolation. inconsistencies between in vitro disk sensitivity and clinical drug response are noted. because of clinical response, the clinician must carefully follow the patient's daily progress to recognize antibiotic treatment failure so that combin ...19751104696
the occurrence of twitching motility among gram-negative bacteria.almost 1000 strains representing well above 50 different species or groups of gram-negative bacteria were examined for twitching motility. this kind of motility was mainly found in strictly aerobic cocci and rods (viz. acinetobacter calcoaceticus, moraxella spp., neisseria gonorrhoeae, n. meningitidis, pseudomonas spp., phenon 3 of thornley that is closely related to acinetobacter, and marine, yellow-pigmented rods), but also in the facultative eikenella corrodens and in anaerobic strains presum ...19751155115
a comparison of the biochemical activities of bacteroides corrodens and eikenella corrodens with those of certain other gramnegative bacteria.tests carried out on strictly anaerobic and facultatively anaerobic strains of "corrodens" bacteria, showed that although these organisms are relatively inactive biochemically, differentiation can be made on the basis of tests that demonstrate reduction of nitrite, hydrolysis of urea and 1-naphthyl acetate, decarboxylation of lysine and ornithine, and sensitivity to certain selective agents included in culture medium. plasma was found to be superior to serum in supporting the growth of all "corr ...19751168723
microbiology of healthy and diseased periodontal sites in poorly controlled insulin dependent diabetics.a group of poorly-controlled insulin dependent diabetes mellitus (iddm) patients were examined in a cross-sectional design for total microbial levels, microbial incidence, and the percent levels of selected periodontal microorganisms. these organisms were selected on the basis of prior reports that associated them with either periodontal disease or health. one periodontally-healthy and one periodontally-diseased site were examined in each iddm patient. increased levels of the periodontal pathoge ...19921315389
humoral igg antibodies to oral microbiota in a population at risk for root-surface caries.mutans streptococci have been strongly implicated in the initiation of dental caries on coronal surfaces. their role in development of root-surface caries is less clear. the etiologic agents of both types of dental caries are likely to elicit systemic immune responses. the objective of the present study, therefore, was to study the association of clinical variables of disease with humoral igg antibodies to nine oral micro-organisms in 314 adult subjects, aged 45-65 years, who were at risk for ro ...19921321176
intrathoracic infections with bacteraemia due to eikenella corrodens as a complication of peritonsillar abscesses: report of a case and review of the literature.a 52-year-old man, without previous disease, presented with dysphagia, dyspnoea, high fever and sore throat after peritonsillar abscesses drainage. physical and complementary examinations were consistent with pericarditis, mediastinitis, pneumonia and pleuritis. blood cultures grew eikenella corrodens resistant to clindamycin and amikacin. we emphasize the pathogenic potential of eikenella corrodens. to the best of our knowledge, this is the first reported case of this organism as a pathogen in ...19921321537
identification of a streptomycin resistance gene and a partial tn3 transposon coding for a beta-lactamase in a periodontal strain of eikenella corrodens.the beta-lactamase gene from a periodontal strain of eikenella corrodens, resistant to penicillins and streptomycin, was inserted into pbgs9 and transformed into escherichia coli dh5 alpha. a 4.7-kb insert of pjml1, one of the transformants, was partially sequenced and found to contain the right section of transposon tn3 from the middle of the tnpr resolvase gene to the right inverted repeat ri(r), including the tem-1 gene. sequences identical to rsf1010 were found on either side of the tn3 sequ ...19921323951
e-test: a new technique for antimicrobial susceptibility testing for periodontal microorganisms.the purpose of the study was to validate the epsilometer test (e-test) method for antimicrobial susceptibility testing of selected periodontopathic microorganisms using the agar dilution method as a standard. the e-test has been developed to provide a direct quantification of antimicrobial susceptibility of microorganisms. the device consists of a predefined, continuous, and exponential gradient of antibiotic concentrations immobilized along a rectangular plastic test strip. after 48 hours incub ...19921324301
anti-proliferative and cytotoxic activity of surface-associated material from periodontopathogenic bacteria.the easily solubilized surface-associated material from three bacterial species associated with periodontal diseases, actinobacillus actinomycetemcomitans, porphyromonas gingivalis and eikenella corrodens, produced dose-dependent inhibition of thymidine incorporation by human fibroblasts, the human monocytic cell line u937 and guinea pig epidermal cells. in contrast, lipopolysaccharides from a. actinomycetemcomitans and p. gingivalis were either inactive or substantially less active over the dos ...19921325147
role of porphyromonas gingivalis 40-kda outer membrane protein in the aggregation of p. gingivalis vesicles and actinomyces viscosus.porphyromonas gingivalis, an important pathogen in periodontitis, produces extracellular vesicles that aggregate with actinomyces viscosus cells. a 40-kda outer membrane protein (omp)-coding gene from p. gingivalis was cloned and the protein was found to be localized in these vesicles. the recombinant 40-kda omp did not show aggregation activity. however, affinity-purified antibody against the recombinant protein significantly inhibited aggregation of p. gingivalis vesicles with a. viscosus cell ...19921329700
comparative in-vitro activity of azithromycin, macrolides (erythromycin, clarithromycin and spiramycin) and streptogramin rp 59500 against oral organisms.the in-vitro activities of azithromycin, clarithromycin, spiramycin and rp 59500 were compared with erythromycin against a wide range of oral organisms which have been implicated in oral infections and/or endocarditis (clindamycin was included for oral streptococci). all compounds tested showed good activity against many of these organisms, although some variation was observed with different species. clarithromycin was the most active of the antibiotics tested against gram-positive anaerobes, in ...19921331019
inhibition of bone dna and collagen production by surface-associated material from bacteria implicated in the pathology of periodontal disease.gentle extraction of oral bacteria implicated in the pathogenesis of periodontal disease, actinobacillus actinomycetemcomitans, porphyromonas gingivalis, or eikenella corrodens, with saline removes the extracellular components while leaving the bacteria intact. this readily-solubilized surface-associated material (sam) has been demonstrated to significantly inhibit dna and collagen synthesis by murine calvaria at concentrations as low as 10 ng/ml. dna and collagen synthesis in isolated calvarial ...19921335499
dna probe and enzyme analysis in periodontal diagnostics.recent research in periodontology has indicated that a finite number of bacterial species are associated with periodontal disease. this has generated the hypothesis that periodontal disease is essentially an infection due to one or more of the putative periodontopathogens; i.e., the specific plaque hypothesis (sph). this microbial specificity paradigm has already changed the way researchers and some clinicians view periodontal disease. the clinician must heed several cautions signs, however, if ...19921336048
corroding characteristics of eikenella corrodens.fourteen strains of eikenella corrodens isolated from human oral cavity were studied to determine corroding characteristics. nine out of the 14 strains produced corroding colonies under anaerobic culture condition. one of them produced corrosion even in an aerobic culture. no morphological differences in surface structures were observed between corroding and non-corroding strains of e. corrodens by transmission electron microscopy. the morphology of corroding colonies of e. corrodens was then ex ...19921358472
septic shock from eikenella corrodens and staphylococcus epidermidis in hiv infection. 19921359296
efficiency of the 5'-terminal sequence (omega) of tobacco mosaic virus rna for the initiation of eukaryotic gene translation in escherichia coli.recent studies have demonstrated that the 5' leader (omega sequence) of tobacco mosaic virus rna has a certain enhancing capacity for translation of mrna in both prokaryotes and eukaryotes. in order to estimate the efficiency of omega to initiate translation of mrna in escherichia coli, in comparison to the shine-dalgarno (s/d) sequence, we have inserted eight different eukaryotic genes into two types of e. coli expression vectors containing one constitutive promoter (p1) but different translati ...19921396694
spleen abscess caused by eikenella corrodens.a case is reported of splenic abscess due to eikenella corrodens, a gram-negative rod which is found as part of normal flora in human mucous surfaces. a 64-year-old man presented with fever, chills, anorexia and abdominal pain. abdominal ultrasound examination showed a perisplenic fluid collection which was considered to be either blood or a subcapsular spleen abscess. the presence of a splenic abscess was later confirmed during surgery and a splenectomy was performed. splenic purulent material ...19921396729
treatment of an infected mandibular graft using tobramycin-impregnated methylmethacrylate beads: report of a case. 19921403285
longitudinal monitoring of humoral antibody in subjects with destructive periodontal diseases.fifty-one subjects (16-61 years old) with evidence of prior destructive periodontal disease were monitored clinically and immunologically at bi-monthly intervals for up to 5 yr. periodontal disease activity, determined as new attachment loss, was detected in 33 of these subjects. only 4 of 51 subjects failed to show an elevated serum antibody level to any of the 18 subgingival species tested. the antibody level threshold established for periodontally healthy subjects was exceeded most often in d ...19921403580
severe soft-tissue infection caused by eikenella corrodens. 19921420698
orbital cellulitis caused by eikenella corrodens.eikenella corrodens is a gram-negative, facultative anaerobic bacillus with specific culture and growth requirements and unusual antibacterial susceptibilities. it has only recently been recognized as a human pathogen. ocular and adnexal infections with this organism are rare especially in children. we treated two children with orbital cellulitis caused by e. corrodens. one was an 8-year-old boy; the other was an 11-year-old girl. orbital cellulitis in both patients occurred after an upper respi ...19921443020
the mechanisms of eikenella corrodens aggregation by salivary glycoprotein and the effect of the glycoprotein on oral bacterial aggregation.the mechanism of aggregation of eikenella corrodens 1073 with e. corrodens aggregating factor (ecaf) which was purified from submandibular-sublingual (sm-sl) saliva was investigated. heating (100 degrees c, 10 minutes) or protease treatment of e. corrodens cells abolished the aggregating activity. the aggregation was inhibited by adding n-acetyl-d-galactosamine (galnac) and saccharides which contain a galactose residue at the non-reducing end. the aggregating activity was sensitive to edta and w ...19921460548
microbiota associated with residual clefts and neighboring teeth in patients with cleft lip, alveolus, and palate.twenty patients with residual clefts or pronounced soft tissue grooves, treated for uni- or bilateral cleft lip, alveolus, and palate were included in this study. ten patients were recalled for dental prophylaxis at regular intervals, 10 patients were not. one microbiologic sample was obtained from the cleft area and two samples from a tooth adjacent to the cleft (sites adjacent and distant to the cleft). between the recall and the nonrecall group there were notable differences in the presence o ...19921472527
susceptibility of anaerobic microorganisms to hypothiocyanite produced by lactoperoxidase.the susceptibility of capnocytophaga ochracea, eikenella corrodens, eubacterium yurii, fusobacterium nucleatum, peptostreptococcus micros, prevotella intermedia, selenomonas sputigena, wolinella recta to hypothiocyanite (oscn-) produced by the lactoperoxidase system was tested. results showed a decrease of bacterial survival rate after oscn- exposure, with an intra- and inter-species variability from 0 to 95% for c. ochracea, 34-100% for e. corrodens, 0-83% for e. yurii, 1-15% for f. nucleatum, ...19921481764
periodontal pathogens in the shallow pockets of immigrants from developing countries.the aim of this study was to examine the distribution of typical periodontitis-associated microorganisms in refugees arriving from non-industrialized countries, and to relate the presence of these organisms to the periodontal condition of the subjects. thirty males between 35-44 years of age were surveyed. dental plaque, calculus, gingivitis, loss of attachment, and probing depths were recorded for all surfaces. a total of 90 microbiological samples were taken with paper points from mesial sites ...19921494449
[multiple pulmonary abscesses caused by eikenella corrodens]. 19921502387
enumeration of subgingival species on primary isolation plates using colony lifts.this study evaluated the feasibility of using a colony lift method and dna probes to enumerate bacterial species cultured on primary isolation plates. fourteen digoxigenin-labeled whole chromosomal dna probes representing 12 subgingival species were validated by hybridization with colony lifts prepared from 249 reference strains of 51 species grown on trypticase soy agar plates supplemented with 5% sheep blood. colonies of reference strains were lifted onto nytran filters from plates and treated ...19921528619
the early colonization of gram-negative anaerobic bacteria in edentulous infants.the occurrence of oral gram-negative anaerobes was examined in 30 edentulous infants (mean age 3 months, range 1-7 months). one pooled swab sample from mucosal surfaces (cheeks, palate, tongue) and one saliva sample was taken from each infant. the samples were cultured aerobically and anaerobically using non-selective and selective media. prevotella (bacteroides) melaninogenica was the most frequently isolated anaerobe, found in 70% of the infants. the other common anaerobes were fusobacterium n ...19921528621
serial doxycycline and metronidazole in prevention of recurrent periodontitis in high-risk patients.the efficacy of metronidazole and doxycycline in preventing recurrent periodontitis was studied in 23 patients. after treatment in the previous 7 months with either bimonthly scaling and 3 weeks of systemic doxycycline (11 subjects) or scaling and placebo (12 subjects), patients were monitored for recurrent periodontitis and were scaled every 2 months. when either a periodontal abscess or greater than 2 mm loss of gingival attachment was observed, metronidazole was administered (250 mg every 8 h ...19921552469
bite wounds and infection.one of every two americans will be bitten by an animal or by another person at some point. bites account for approximately 1% of all visits to emergency rooms; injuries inflicted by dogs are most common. the bacteria involved in infection of bite wounds include pasteurella multocida, staphylococcus aureus, staphylococcus intermedius, alpha-hemolytic streptococci, capnocytophaga canimorsus, and other members of the oral flora. anaerobic bacteria are present in approximately one-third of bite woun ...19921562653
eikenella corrodens and group c streptococci. 19921562674
a comparison of antimicrobial activity of ofloxacin, l-ofloxacin, and other oral agents for respiratory pathogens.the attainable inhibitory ratios (ar) for oral antibiotics were calculated by using literature reports of concentrations attained in respiratory secretions for amoxicillin-clavulanic acid (amx/ca), ofloxacin (ofl), l-ofloxacin (l-ofl), cefuroxime (cefu), ciprofloxacin (cip), and enoxacin (eno), and using microdilution minimum inhibitory concentration data of these antimicrobials against the common bacterial respiratory pathogens. ar of each antibiotic against the pathogens was expressed as multi ...19921572139
[acute bacterial parotiditis and sjögren's syndrome]. 19921598020
modulation of human neutrophil adherence by oral bacteria.polymorphonuclear neutrophils (pmns) comprise over 90 per cent of leukocytes in the oral cavity. although these phagocytic cells have primary defence roles in the gingiva, their stimulation by micro-organisms may also cause substantial tissue damage due to the release of lysosomal enzymes and oxygen radicals. adherence of pmns to the endothelium and their subsequent diapedesis and egress to areas of infection are considered early vital events in the inflammatory process. in this study, oral bact ...19921605750
[polymorphonuclear leukocyte-mediated effects on human oral keratinocytes by periodontopathic bacterial extracts].in order to investigate the polymorphonuclear leukocyte-mediated oral keratinocyte injury, the author established a method to culture keratinocytes (scc9 and gingival keratinocytes) and subjected to the cell detachment assay by polymorphonuclear leukocytes and/or bacterial ultrasonic extracts from actinobacillus actinomycetemcomitans y4, bacteroides forsythus omz 408, fusobacterium nucleatum atcc 10953, capnocytophaga sputigena 4 and eikenella corrodens 1073. the bacterial extracts alone caused ...19921607829
clinical and microbiological patterns of adults with periodontitis.although current data suggest that periodontitis may actually be multiple diseases each with varying responses to therapy, little evidence exists to support this theory in adult patients. this report describes the design and initial findings of a longitudinal field trial involving the diagnosis and treatment of adult and refractory periodontitis patients in private practice. adult patients (n = 221) who met specific clinical criteria were selected from the private practices of 22 periodontists. ...19911663156
[tubo-ovarian abscess caused by eikenella corrodens]. 19911687993
the relationship of serum igg antibody titers to periodontal pathogens to indicators of the host response in crevicular fluid.in this study; the relationship of indicators of the local host response in gingival crevicular fluid (gcf) to the serum antibody titer to periodontal pathogens was examined. 15 patients with chronic adult periodontitis were studied. gcf was collected and analyzed for the total amount of igg, igm, the lysosomal enzyme b-glucuronidase (bg) and alpha-2-macroglobulin (alpha 2m). at the same examination, serum from these patients was collected, and enzyme-linked immunosorbent assays used to determin ...19901696949
brodie's abscess caused by eikenella corrodens. 19911753127
use of monoclonal antibodies with neutralizing effects on toxic antigens from human bacterial plaque to detect specific bacteria by colony blotting.inflammatory periodontal diseases are provoked by bacteria which adhere to teeth at the gingival margin and form plaques containing toxins detectable by their effect on mammalian cells in culture. the aim of this study was to make toxin-neutralizing monoclonal antibodies and determine whether they detect antigen in specific oral bacteria. bacterial plaque was collected from teeth and homogenized, and the fluid phase (plaque extract) was boiled or first fractionated over sephacryl s-300. hybridom ...19911757553
fluorescence immunoassay for detecting periodontal bacterial pathogens in plaque.a particle concentration fluorescence immunoassay has been modified into a bacterial concentration fluorescence immunoassay (bcfia) to rapidly detect periodontopathic bacteria in human plaque samples. the bcfia utilizes fluorescently tagged monoclonal antibodies (mabs) directed against the lipopolysaccharide of selected gram-negative plaque bacteria. microorganisms closely associated with periodontal disease that can be identified in plaque with the bcfia include porphyromonas gingivalis, bacter ...19911761686
[subgingival microflora in children of early childhood, school age and circumpuberty. the proportion and frequency of gram-negative bacteria in periodontally healthy and gingivitis groups].the present study characterized the microbial profiles of the gingival sulci in children. subgingival samples from 36 gingivitis lesions of 18 patients and 36 sites in 18 healthy persons were examined. the tested individuals were divided into three stages according to physiological maturation i.e. early childhood, school age, circumpuberty. puberty was confirmed through examination of wrist radiographs. using continuous anaerobic techniques, samples were dispersed, diluted and then inoculated on ...19911784868
adherence to experimental pellicle of rough-type lipopolysaccharides from subgingival plaque bacteria.the adherence of lipopolysaccharides (lpss) from periodontal disease-associated bacteria to saliva-coated hydroxyapatite (s-ha) and serum-coated ha beads was examined by chromogenic limulus activity (toxicolor test). phenol-water extracted lps preparations from bacteroides intermedius, fusobacterium nucleatum, actinobacillus actinomycetemcomitans, eikenella corrodens, and rough-type lps from escherichia coli adhered to s-ha and serum-coated beads and agglutinated human erythrocytes. the adhered ...19911812466
antimicrobial activity of flurbiprofen and ibuprofen in vitro against six common periodontal pathogens.nonsteroidal antiinflammatory drugs (nsaids) such as flurbiprofen and ibuprofen, have been shown to inhibit the inflammation and alveolar bone loss associated with chronic destructive periodontal disease. however, the direct effect of nsaids on the gingival crevice microflora has not been studied. the purpose of this investigation was to evaluate the antimicrobial activity of ibuprofen and flurbiprofen in vitro on six commonly isolated periodontal pathogens. the bacterial strains evaluated were ...19911812907
a heat stable hemagglutinating activity of eikenella corrodens.strains of eikenella corrodens and fusobacterium nucleatum were shown to possess lectinlike attachment factors. the present investigators found that e. corrodens has a heat stable factor which agglutinates sheep, mouse, and human erythrocytes. the activity is not abolished by additions of galactose or lactose. lipopolysaccharide preparations from e. corrodens strains possessed strong hemagglutinating activity. lpss of f. nucleatum did not agglutinate any erythrocytes tested. sds-page patterns st ...19911819444
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