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emerging sars-cov-2 variants expand species tropism to murines.wildtype mice are not susceptible to sars-cov-2 infection. emerging sars-cov-2 variants, including b.1.1.7, b.1.351, p.1, and p.3, contain mutations in spike that has been suggested to associate with an increased recognition of mouse ace2, raising the postulation that these sars-cov-2 variants may have evolved to expand species tropism to wildtype mouse and potentially other murines. our study evaluated this possibility with substantial public health importance.202134689086
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