Publications

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host and viral traits predict zoonotic spillover from mammals.the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ...201728636590
identification of ebola virus sequences present as rna or dna in organs of terrestrial small mammals of the central african republic.the life cycle of the ebola (ebo) virus remains enigmatic. we tested for ebo virus in the organs of 242 small mammals captured during ecological studies in the central african republic. ebo virus glycoprotein or polymerase gene sequences were detected by reverse transcription pcr in rna extracts of the organs of seven animals and by pcr in dna extract of one animal. neither live virus nor virus antigen was detected in any organ sample. direct sequencing of amplicons identified the virus as being ...199910580275
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