| host and viral traits predict zoonotic spillover from mammals. | the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ... | 2017 | 28636590 |
| markers of foamy virus infections in monkeys, apes, and accidentally infected humans: appropriate testing fails to confirm suspected foamy virus prevalence in humans. | foamy viruses (fvs) persist in healthy individuals of various mammalian species, including nonhuman primates. laboratory markers of fv infection are (1) virus in throat epithelium or peripheral blood lymphocytes (pbls), (2) proviral dna sequences in pbls and various solid organs, and (3) antibodies reactive to viral antigens on western blots, in radioimmunoprecipitation tests, and in immunofluorescence assays. using pcr and serological tests, we readily detected fv markers in naturally infected ... | 1995 | 7734189 |