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outbreaks of highly pathogenic avian influenza in zoo birds caused by ha clade 2.3.4.4 h5n6 subtype viruses in japan in winter 2016.in late 2016, two zoos, one in northern japan and the other in central japan, experienced highly pathogenic avian influenza (hpai) outbreaks, in which multiple zoo birds were infected with h5n6 subtype hpai virus (hpaiv). here, we report an overview of these hpai outbreaks. hpaiv infections were confirmed by virus isolation in three black swans (cygnus atratus) and three snowy owls (bubo scandiacus) kept in the omoriyama zoo hospital. at higashiyama zoo and botanical gardens, following the death ...202031605424
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