| emergence of a new arbovirus disease in brazil. i. isolation and characterization of the etiologic agent, rocio virus. | in april, 1975, an epidemic of human encephalitis was detected in several counties in the state of são paulo, brazil; the epidemic continued into 1976. a virus was isolated from central nervous system (cns) tissues of a 39-year-old male who died on december 8, 1975; the virus was found to be a new flavivirus for which the name rocio virus is proposed. nine further isolations of rocio virus were obtained from cns tissues of 17 patients who died with clinical symptoms of encephalitis. isolations o ... | 1978 | 665659 |