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tree shrew as a new animal model for the study of dengue virus.dengue virus is a significant public health threat worldwide; however, the pathogenesis of dengue disease remains poorly understood due to lack of appropriate small animal models. tree shrews are an emerging experimental animal model for the study of human diseases due to their resemblance of genetic characteristics to primate animals. herein we report that dengue infection in tree shrews elicits resemble clinical symptoms as in humans. dengue fever (△2°c> normal body temperature) developed in ~ ...202133841402
[preliminary investigation of viruses to the wild tree shrews (tupaia belangeri chinese)].virological testing and monitoring is a fundamental part of quality control of experimental animals. however, there are few papers regarding the spectrum and status of natural infection in wild tree shrews with human and animal pathogenic viruses. using enzyme-linked immunosorbent adsorption assay (elisa), we tested sixty wild tree shrews captured from qinglong, an outskirt region of kunming, yunnan province, china for eleven viruses, including herpes simplex virus, coxsackie virus, influenza vi ...201121341387
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