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oncogene and its production of an avian sarcoma virus y73.the y73 strain of avian sarcoma virus isolated from a transplantable chicken tumor was defective in its replicating capacity. the virus caused sarcoma but not acute leukosis in chickens even when inoculated intravenously. it induced transformed cell-foci in cultured fibroblasts and the viral genome responsible for in vitro transformation was 26s rna. the rna was composed of sequences in common with helper virus rna and y73-specific sequence. the specific sequence "yes" did not hybridize with com ...19826300025
isolation of a sarcoma virus from a spontaneous chicken tumor.a spontaneous tumor was obtained from a hen of white-leghorn stock raised in a local farm in yamaguchi city, in december 1973. the tumor had characteristics of fibro- or myxofibro-sarcoma and could be maintained by transplantation in chickens of similar flocks. this tumor was proved to produce sarcoma virus at 33rd passage and the transforming virus was designated as y73 sarcoma virus. biological studies suggested that the virus recovered from the tumor belonged to avian leukosis-sarcoma complex ...1978220128
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