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isolation and characterization of a hepatitis b virus endemic in herons.a new hepadnavirus (designated heron hepatitis b virus [hhbv]) has been isolated; this virus is endemic in grey herons (ardea cinerea) in germany and closely related to duck hepatitis b virus (dhbv) by morphology of viral particles and size of the genome and of the major viral envelope and core proteins. despite its striking similarities to dhbv, hhbv cannot be transmitted to ducks by infection or by transfection with cloned viral dna. after the viral genome was cloned and sequenced, a comparati ...19883418788
characterization of infectious and defective cloned avian hepadnavirus genomes.the infectivity in vivo, replication competence in vitro, and expression of viral genes of several molecularly cloned duck hepatitis b virus (dhbv) genomes were investigated. in addition, replication competence, core protein expression, and secretion of viral proteins were investigated for a grey heron hepatitis b virus genome. except two, all dhbv isolates tested induced a systemic infection in pekin ducks when injected as cloned viral dna into the liver. after transfection of chicken hepatoma ...19911926780
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