| antigenic variation of european haemorrhagic fever with renal syndrome virus strains characterized using bank vole monoclonal antibodies. | monoclonal antibodies (mabs) against puumala (puu) virus, the aetiological agent of nephropathia epidemica, were produced by fusing activated spleen cells from a bank vole (clethrionomys glareolus) with the mouse myeloma cell line sp2/0. this novel approach, utilizing the natural vector of puu virus for hybridoma production, proved to be highly efficient, and eight stable puu virus-specific heterohybridomas were isolated and characterized. the bank vole mabs were all specific for the nucleocapsi ... | 1991 | 1716651 |
| partial characterization of a hantavirus isolated from a clethrionomys glareolus captured in belgium. | a hantavirus was isolated in vero-e6 cells from lungs of a free living bank vole (clethrionomys glareolus) captured in turnhout, province of antwerp--northern part of belgium. with help of monoclonal antibodies the belgian hantavirus isolate could be clearly differentiated from hantaan virus strain 76-118, prospect hill virus strain ph1 and sr11, a hantavirus isolated from laboratory wistar rat in japan, but not from the nephropathia epidemica virus strain hällnäs. | 1987 | 2886029 |
| [use of monoclonal antibodies for differentiating strains of the virus causing the hemorrhagic fever with renal syndrome]. | using monoclonal antibody and animal immune sera the experiment confirmed the existence of antigenic relationships between the strains of virus of hemorrhagic fever with renal syndrome (hfrs) isolated in the ussr from clethrionomys glareolus and members of all known serotypes of hfrs virus. clear-cut differentiation was made from serotypes apodemus and rattus, and cross-relationships were shown between the strains isolated in the ussr and prospect hill virus (phv), a member of the serotype micro ... | 1987 | 3124351 |