Publications
| immune response to marburg virus angola infection in nonhuman primates. | the 2005 outbreak of marburg virus (marv) infection in angola was the most lethal marv infection outbreak in history, with a case-fatality rate (90%) similar to that for zaire ebolavirus (ebov) infection. however, very little is known about the pathogenicity of marv angola, as few studies have been conducted to date. therefore, the immune response was examined in marv angola-infected nonhuman primates. | 2015 | 25957966 |
| virulence of marburg virus angola compared to mt. elgon (musoke) in macaques: a pooled survival analysis. | angola variant (marv/ang) has replaced mt. elgon variant musoke isolate (marv/mte-mus) as the consensus standard variant for marburg virus research and is regarded as causing a more aggressive phenotype of disease in animal models; however, there is a dearth of published evidence supporting the higher virulence of marv/ang. in this retrospective study, we used data pooled from eight separate studies in nonhuman primates experimentally exposed with either 1000 pfu intramuscular (im) marv/ang or m ... | 2018 | 30469360 |