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susceptibility of sheep to experimental co-infection with the ancestral lineage of sars-cov-2 and its alpha variant.severe acute respiratory syndrome coronavirus 2 (sars-cov-2) is responsible for a global pandemic that has had significant impacts on human health and economies worldwide. sars-cov-2 is highly transmissible and the cause of coronavirus disease 2019 (covid-19) in humans. a wide range of animal species have also been shown to be susceptible to sars-cov-2 infection by experimental and/or natural infections. domestic and large cats, mink, ferrets, hamsters, deer mice, white-tailed deer, and non-huma ...202134816258
structural analysis of covid-19 spike protein in recognizing the ace2 receptor of different mammalian species and its susceptibility to viral infection.the pandemic covid-19 was caused by a novel coronavirus-2 (sars-cov-2) that infects humans through the binding of glycosylated sars-cov-2 spike 2 protein to the glycosylated ace2 receptor. the spike 2 protein recognizes the n-terminal helices of the glycosylated metalloprotease domain in the human ace2 receptor. to understand the susceptibility of animals for infection and transmission, we did sequence and structure-based molecular interaction analysis of 16 ace2 receptors from different mammali ...202133552834
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