| the effect of 1,10-phenanthroline on the chromosome damage and sister-chromatid exchanges induced by streptozotocin in mammalian and insect cells. | the effect of the metal chelating agent 1,10-phenanthroline (pnt) on the streptozotocin (stz)-induced chromosomal aberrations (cas) and sister-chromatid exchanges (sces) in chinese hamster ovary (cho) and mosquito (aedes albopictus) cells was investigated. treatment of cho and mosquito cells with stz produced a significant and dose-response increase in the yield of cas as well as sces (p<0.05). the addition of pnt prevented the induction of cas by stz in both types of cells, causing a significan ... | 2000 | 10751605 |
| chromosomal response of insect and mammalian cells to streptonigrin: a comparative study. | we assessed the chromosomal response of insect (mosquito, aedes albopictus) and mammalian (chinese hamster ovary, cho) cells to streptonigrin (sn). both types of cells were pulse-treated for 20 min with increasing doses of sn and the frequency of chromosome aberrations and sister chromatid exchanges (sces) for each sn dose was determined. our results show that the sn doses inducing remarkable chromosome damage (expressed as frequency of aberrations per cell and per chromosome) in cho cells fail ... | 1998 | 9882007 |
| factors affecting zero background frequency of sister-chromatid exchange in mosquito cells. | a background level of sister-chromatid exchange (sce) is found in mammalian cells. however, in the somatic cells of drosophila melanogaster, there was no spontaneous sce if a minimum concentration of bromodeoxyuridine (brdu) was used. in this communication we report that in a mosquito (aedes albopictus) cell line (c6/36), some cells also have no background sce (0-sce). subclones of high (44%) or low (12%) frequency of 0-sce cells were obtained, but none of them contained 100% 0-sce cells. increa ... | 1993 | 8332078 |
| excito-repellency and biological safety of β-caryophyllene oxide against aedes albopictus and anopheles dirus (diptera: culicidae). | the activity of β-caryophyllene oxide as either a contact or noncontact repellent was evaluated against two laboratory strains (aedes albopictus and anopheles dirus) using an excito-repellency test system. n, n-diethyl-3-methylbenzamide (deet) was used as a standard reference baseline for comparative purposes. β-caryophyllene oxide and deet were tested at concentrations of 0.1, 0.25, 0.5 and 1.0% (v/v). in addition, the phototoxic and genotoxic effects of β-caryophyllene oxide were investigated ... | 2020 | 32485168 |