| effect of ivermectin on two filaria-vector pairs. brugia malayi-aedes aegypti; litomosoides sigmodontis-bdellonyssus bacoti. | the effect of ivermectin was studied on two filaria-vector pairs, brugia malayi-aedes aegypti and litomosoides sigmodontis-bdellonyssus bacoti. the rodent hosts, respectively mastomys coucha and meriones unguiculatus, were treated with ivermectin doses of 0.05 mg/kg, or 0.2 mg/kg or 2 mg/kg. batches of vectors were fed on rodents, infected or not, treated or not, from h7 to d43 post-ivermectin. vector survival was observed and dissections were performed to study the filarial development. it appe ... | 1993 | 8215116 |
| setaria digitata microfilaraemia in mastomys coucha: an animal model for chemotherapeutic and immunobiological studies. | intraperitoneal implantation of adult gravid females of the bovine filarial parasite, setaria digitata in mastomys coucha was found to induce microfilaraemia lasting for about 125 days. the microfilariae (mf) could be detected as early as 4 days post-implantation (p.i.) and peak levels of about 30 mf in 20 microliters of blood were observed by 21 days. a significant positive correlation was found between mf density and the body weight of recipients pre-implantation. the implanted adult worms wer ... | 1996 | 8873474 |
| bacillus sphaericus interferes with the development of brugia malayi in aedes aegypti. | aedes aegypti (black-eyed liverpool strain) were exposed to a sublethal dose (ld25) of bacillus sphaericus and were fed to mastomys coucha infected with brugia malayi. the development of the filarial parasite was found to be arrested mostly at the second larval stage. the infection (p < 0.05), infectivity rates (p < 0.001) and l3 load (p < 0.001) were found to be reduced significantly in the treated group. | 1999 | 10526424 |