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new sars-cov-2 infection detected in an italian pet cat by rt-qpcr from deep pharyngeal swab.the pandemic respiratory disease covid-19, caused by severe acute respiratory syndrome coronavirus 2 (sars-cov-2), emerged in wuhan in december 2019 and then spread throughout the world; italy was the most affected european country. despite close pet-human contact, little is known about the predisposition of pets to sars-cov-2. among these, felines are the most susceptible. in this study, a domestic cat with clear clinical signs of pneumonia, confirmed by rx imaging, was found to be infected by ...202032932800
sars-cov-2 in quarantined domestic cats from covid-19 households or close contacts, hong kong, china.we tested 50 cats from coronavirus disease households or close contacts in hong kong, china, for severe acute respiratory syndrome coronavirus 2 rna in respiratory and fecal samples. we found 6 cases of apparent human-to-feline transmission involving healthy cats. virus genomes sequenced from 1 cat and its owner were identical.202032938527
sars-cov-2 infection, disease and transmission in domestic cats.severe acute respiratory syndrome coronavirus 2 (sars-cov-2) is the cause of coronavirus disease 2019 (covid-19) and responsible for the current pandemic. recent sars-cov-2 susceptibility studies in cats show that the virus can replicate in these companion animals and transmit to other cats. here, we present an in-depth study of sars-cov-2 infection, disease and transmission in domestic cats. cats were challenged with sars-cov-2 via intranasal and oral routes. one day post challenge (dpc), two s ...202033028154
sars-cov-2 natural transmission from human to cat, belgium, march 2020.in march 2020, a severe respiratory syndrome developed in a cat, 1 week after its owner received positive test results for severe acute respiratory syndrome coronavirus 2. viral rna was detected in the cat's nasopharyngeal swab samples and vomitus or feces; immunoglobulin against the virus was found in convalescent-phase serum. human-to-cat transmission is suspected.202032788033
coronavirus in cat flea: findings and questions regarding covid-19.the coronavirus disease 19 (covid-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (sars-cov-2) has affected millions of people worldwide. recent evidence raised the question about the possibility that cats may be a domestic host for sars-cov-2 with unknown implications in disease dissemination. based on the fact that the domestic cat flea, ctenocephalides felis, are abundant ectoparasites infesting humans, companion animals and wildlife and that coronavirus-like agents hav ...202032778178
ace2 expression in the cat and the tiger gastrointestinal tracts.angiotensin-converting enzyme 2 (ace2) has been identified as the functional receptor for severe acute respiratory syndrome-coronavirus-2 (sars-cov-2). it has been identified in the human gastrointestinal tract (git), and sars-cov-2 has been isolated in human and animal fecal samples. the aim of the present study was to investigate the expression of ace2 in the gastrointestinal tract of domestic (cat) and wild (tiger) felines. samples of the pylorus, duodenum, and distal colon were collected fro ...202032903561
experimental infection of domestic dogs and cats with sars-cov-2: pathogenesis, transmission, and response to reexposure in cats.the pandemic caused by severe acute respiratory syndrome coronavirus 2 (sars-cov-2) has reached nearly every country in the world with extraordinary person-to-person transmission. the most likely original source of the virus was spillover from an animal reservoir and subsequent adaptation to humans sometime during the winter of 2019 in wuhan province, china. because of its genetic similarity to sars-cov-1, it is probable that this novel virus has a similar host range and receptor specificity. du ...202032994343
predicting susceptibility to sars-cov-2 infection based on structural differences in ace2 across species.severe acute respiratory syndrome coronavirus 2 (sars-cov-2) is the cause of the global pandemic of coronavirus disease-2019 (covid-19). sars-cov-2 is a zoonotic disease, but little is known about variations in species susceptibility that could identify potential reservoir species, animal models, and the risk to pets, wildlife, and livestock. certain species, such as domestic cats and tigers, are susceptible to sars-cov-2 infection, while other species such as mice and chickens are not. most ani ...202033015868
potential zoonotic sources of sars-cov-2 infections.the severe acute respiratory syndrome coronavirus-2 (sars-cov-2) causing coronavirus disease-2019 (covid-19) likely has evolutionary origins in other animals than humans based on genetically related viruses existing in rhinolophid bats and pangolins. similar to other animal coronaviruses, sars-cov-2 contains a functional furin cleavage site in its spike protein, which may broaden the sars-cov-2 host range and affect pathogenesis. whether ongoing zoonotic infections are possible in addition to ef ...202033034151
infection of dogs with sars-cov-2.severe acute respiratory syndrome coronavirus 2 (sars-cov-2) was first detected in wuhan in december 2019 and caused coronavirus disease 2019 (covid-19)1,2. in 2003, the closely related sars-cov had been detected in domestic cats and a dog3. however, little is known about the susceptibility of domestic pet mammals to sars-cov-2. here, using pcr with reverse transcription, serology, sequencing the viral genome and virus isolation, we show that 2 out of 15 dogs from households with confirmed human ...202032408337
highly conserved binding region of ace2 as a receptor for sars-cov-2 between humans and mammals.several cases of severe acute respiratory syndrome coronavirus 2 (sars-cov-2) infection transmitted from human owners to their dogs have recently been reported. the first ever case of sars-cov-2 transmission from a human owner to a domestic cat was confirmed on march 27, 2020. a tiger from a zoo in new york, usa, was also reportedly infected with sars-cov-2. it is believed that sars-cov-2 was transmitted to tigers from their caretakers, who were previously infected with this virus. on may 25, 20 ...202032921279
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