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distribution and seasonal variation of ljungan virus in bank voles (myodes glareolus) in fennoscandia.ljungan virus (lv) is a picornavirus originally isolated from swedish bank voles ( myodes glareolus ) in 1998. the association of lv with human disease has been debated ever since, but fundamental data on the ecology of the virus are still lacking. here we present results of the first intensive study on the prevalence of lv in bank voles trapped in fennoscandia (sweden and finland) from 2009-2012 as determined by pcr. using an lv-specific rt-pcr, lv was detected in the liver of 73 out of 452 (16 ...201728192046
serological survey in the finnish human population implies human-to-human transmission of ljungan virus or antigenically related viruses.ljungan virus (lv) is a picornavirus related to human parechoviruses (hpev). the virus has been found in bank voles (myodes glareolus) and several other rodent species, and suggested to have zoonotic potential. thus far, seroepidemiological data on lv infections in humans are scarce. in this study, we aimed to characterize the demographic and geographical distribution of lv-reactive antibodies in finland, and to investigate its occurrence in patients suspected of having a rodent-borne disease, n ...201626489898
evolutionary relationships of ljungan virus variants circulating in multi-host systems across europe.the picornavirus named 'ljungan virus' (lv, species parechovirus b) has been detected in a dozen small mammal species from across europe, but detailed information on its genetic diversity and host specificity is lacking. here, we analyze the evolutionary relationships of lv variants circulating in free-living mammal populations by comparing the phylogenetics of the vp1 region (encoding the capsid protein and associated with lv serotype) and the 3dpol region (encoding the rna polymerase) from 24 ...202134372523
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