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localized conserved regions of the s rna gene products of bunyaviruses are revealed by sequence analyses of the simbu serogroup aino virus.the complete nucleotide sequence has been determined for the s rna of aino virus, a member of the simbu serogroup (bunyavirus genus, family bunyaviridae). the s rna is 850 nucleotides long (2.76 x 10(5) daltons) and in the viral complementary sequence has a short 5' non-coding region of 34 nucleotides and a more extensive 3' non-coding region of 117 nucleotides. the 3'-5' complementarity of the aino s rna is about 25 residues long, depending on the arrangement. the aino sequence predicts that, l ...19846532000
teratogenicity of aino virus in the chick embryo.aino virus (janar 28 strain), a possible agent of a congenital anomaly of calves, was inoculated into the yolk sac of chick embryos at a dose of 10(2), 10(3), 10(4) or 10(5) tcid50 0.2 ml-1 at four, six or eight days of incubation. at 21 days of incubation all the unhatched embryos or hatched chickens in the experimental and control groups were sacrificed for pathological examination. the incidence of hydranencephaly, cerebellar hypoplasia or agenesis and arthrogryposis or scoliosis was highest ...19979243724
isolation of aino virus from an aborted bovine fetus.a male fetus of gestation day 187 was aborted from a holstein-friesian cow in an epizootic of the aino virus (ainov) in september 1995. neutralizing antibody titers against ainov were 1:128, 1:16 and 1:64 in the dam serum, fetal ascites and cerebrospinal fluid, respectively. a 10% brain suspension of the aborted fetus was prepared immediately after autopsy, rinsed three times and sonicated before centrifugation. the supernatant was then inoculated into hmlu-1 cell cultures. a cytopathic effect w ...19989819769
serological survey of arthropod-borne viruses among wild boars in japan.a total of 90 blood samples were collected from wild boars in the kyushu region of japan, and a seroepidemiological survey for 7 arthropod-borne viruses was performed using hemagglutination inhibition tests. the individual seropositive rates for each virus were 52.2% for japanese encephalitis virus (jev), 47.8% for getah virus (getv), 13.3% for akabane virus, 10.0% for aino virus and less than 5% for bluetongue virus, chuzan virus and ibaraki virus. the results indicated that among the 7 viruses ...200919721358
congenital cerebellar dysplasia in white leghorn chickens (gallus gallus domesticus).congenital cerebellar anomalies have been rarely reported in birds. we examined cerebellums with disorganized folia from seven specific-pathogen-free white leghorn chickens (gallus gallus domesticus). islands of heterotopic cortex were distributed from the deeper cortices to the medulla in the cerebellum. the characteristic lesions were composed of randomly admixed components of the cerebellar cortex, including purkinje cells, a molecular layer and granular cells. immunofluorescent analysis reve ...201424498885
seroprevalence survey of aino virus infection in dairy cattle of fukuoka, japan in 1990.the seroprevalence and seroconversion to aino virus infection were epidemiologically analyzed in fukuoka prefecture, by a cohort study, in 1990. serum samples (872) were taken from 436 cattle of 128 farms in five different districts at twice sampling with four month-intervals and were tested by a serum neutralizing test with aino virus. in the first sampling (may-july), 38.3% of sera and 40.6% of farms tested were positive and 33.3% of cattle and 40.6% of farms were sero-converted during the per ...19957756398
a farming systems study of abortion in dairy cattle on the atherton tableland. 2. the pattern of infectious diseases.the role of infectious agents on dairy farms on the atherton tableland in tropical north queensland was studied as part of a comprehensive investigation into the causes of bovine abortion. the prevalence of antibody in serums collected from 7 herds whose annual abortion rates ranged from 3% to 21% were as follows: leptospira hardjo 49.9% (426/853), l. pomona 0.4% (3/851), bovine virus diarrhoea (bvd) 33.7% (35/104). infectious bovine rhinotracheitis virus (ibr) 11.5% (12/105), akabane virus 92.2 ...19892505741
what can akabane disease teach us about other arboviral diseases.viruses of the simbu serogroup cause lesions to foetuses that are seen at birth and that correlate with the stage of pregnancy at which the dam first contracts the virus. the simbu serogroup comprises arboviruses known to cause outbreaks of abnormal parturitions in domestic ruminants; these abnormalities include abortion, stillbirth, and congenitally deformed neonates. simbu serogroup members include: akabane virus (akav), aino virus, cache valley virus, and schmallenberg virus. lately, dairy he ...201627723047
evaluating the protective efficacy of a trivalent vaccine containing akabane virus, aino virus and chuzan virus against schmallenberg virus infection.schmallenberg virus (sbv), an arthropod borne pathogen, spread rapidly throughout the majority of europe since 2011. it can cause a febrile disease, milk drop, diarrhea, and fetal malformation in ruminants. sbv, a member of the simbu serogroup within the genus orthobunyavirus, is closely related to akabane virus (akav) and aino virus (ainov) among others. in the present study, 4 holstein-friesian calves were immunized twice four weeks apart with a multivalent, inactivated vaccine against akav an ...201324313924
common, emerging, vector-borne and infrequent abortogenic virus infections of cattle.this review deals with the aetiology and the diagnosis of bovine viral abortion. while the abortion rates on beef and dairy cattle farms usually do not exceed 10%, significant economic losses because of abortion storms may be encountered. determining the cause of abortions is usually a challenge, and it generally remains obscure in more than 50% of the necropsy submitted foetuses. bovine viral diarrhoea virus and bovine herpesvirus-1 are the most common viruses causally associated with bovine ab ...201121733134
serosurveillance of viral diseases in korean native goats (capra hircus).a total of 804 goat sera were collected from 144 goat farms in five regions of south korea during a period between 2005 and 2006 and screened for the antibodies of viral pathogens in ruminants. the individual seropositive rates for each virus were 13.7% (110/804) for bovine herpesvirus-1 (bhv-1), 9.5% (76/804) for bovine parainfluenza type-3 virus (pi-3v), 5.5% (44/804) for akabane virus (akav), 13.3% (107/804) for aino virus (ainv), 2.0% (16/804) for chuzan virus (chuv) and 1.0% (8/804) for bov ...200818840974
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