| discovery of seven novel mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavirus. | recently, we reported the discovery of three novel coronaviruses, bulbul coronavirus hku11, thrush coronavirus hku12, and munia coronavirus hku13, which were identified as representatives of a novel genus, deltacoronavirus, in the subfamily coronavirinae. in this territory-wide molecular epidemiology study involving 3,137 mammals and 3,298 birds, we discovered seven additional novel deltacoronaviruses in pigs and birds, which we named porcine coronavirus hku15, white-eye coronavirus hku16, sparr ... | 2012 | 22278237 |
| development and application of an elisa for the detection of porcine deltacoronavirus igg antibodies. | porcine deltacoronavirus (pdcov), also known as porcine coronavirus hku15, was first detected in north america in early 2014 and associated with enteric disease in pigs, resulting in an urgent need to further investigate the ecology of this virus. while assays detecting nucleic acids were implemented quickly, assays to detect anti-pdcov antibodies have not been available. in this study, an indirect anti-pdcov igg enzyme-linked immunosorbent assay (elisa) based on the putative s1 portion of the s ... | 2015 | 25881086 |
| development of monoclonal antibodies and serological assays including indirect elisa and fluorescent microsphere immunoassays for diagnosis of porcine deltacoronavirus. | a novel porcine deltacoronavirus (pdcov), also known as porcine coronavirus hku15, was reported in china in 2012 and identified in the u.s. in early 2014. since then, pdcov has been identified in a number of u.s. states and linked with clinical disease including acute diarrhea and vomiting in the absence of other identifiable pathogens. since pdcov was just recently linked with clinical disease, few specific antibody-based reagents were available to assist in diagnosis of pdcov and limited serol ... | 2016 | 27277214 |
| porcine coronavirus hku15 detected in 9 us states, 2014. | | 2014 | 25153521 |
| detection and genetic characterization of deltacoronavirus in pigs, ohio, usa, 2014. | in ohio, united states, in early 2014, a deltacoronavirus was detected in feces and intestine samples from pigs with diarrheal disease. the complete genome sequence and phylogenetic analysis of the virus confirmed that the virus is closely related to a porcine deltacoronavirus (porcine coronavirus hku15) reported in hong kong in 2012. | 2014 | 24964136 |
| complete genome sequence of porcine coronavirus hku15 strain in2847 from the united states. | porcine coronavirus hku15 (porcov hku15) was first detected in pigs with clinical diseases in february 2014 in the united states. here, we report the complete genome sequence of indiana strain in2847, which might be useful for understanding the molecular profile of porcov hku15. | 2014 | 24744332 |
| coronavirus hku15 in respiratory tract of pigs and first discovery of coronavirus quasispecies in 5'-untranslated region. | coronavirus hku15 is a deltacoronavirus that was discovered in fecal samples of pigs in hong kong in 2012. over the past three years, coronavirus hku15 has been widely detected in pigs in east/southeast asia and north america and has been associated with fatal outbreaks. in all such epidemiological studies, the virus was generally only detected in fecal/intestinal samples. in this molecular epidemiology study, we detected coronavirus hku15 in 9.6% of the nasopharyngeal samples obtained from 249 ... | 2017 | 28634353 |
| discovery and sequence analysis of four deltacoronaviruses from birds in the middle east reveal interspecies jumping with recombination as a potential mechanism for avian-to-avian and avian-to-mammalian transmission. | the emergence of middle east respiratory syndrome showed once again that coronaviruses (covs) in animals are potential source for epidemics in humans. to explore the diversity of deltacoronaviruses in animals in the middle east, we tested fecal samples from 1,356 mammals and birds in dubai, the united arab emirates. four novel deltacoronaviruses were detected from eight birds of four species by reverse transcription-pcr (rt-pcr): falcov uae-hku27 from a falcon, houcov uae-hku28 from a houbara bu ... | 2018 | 29769348 |
| beta- and novel delta-coronaviruses are identified from wild animals in the qinghai-tibetan plateau, china. | outbreaks of severe virus infections with the potential to cause global pandemics are increasingly concerning. one type of those commonly emerging and re-emerging pathogens are coronaviruses (sars-cov, mers-cov and sars-cov-2). wild animals are hosts of different coronaviruses with the potential risk of cross-species transmission. however, little is known about the reservoir and host of coronaviruses in wild animals in qinghai province, where has the greatest biodiversity among the world's high- ... | 2020 | 33259031 |