genetic diversity of hantaviruses associated with hemorrhagic fever with renal syndrome in the far east of russia. | to identify the hantaviruses causing hemorrhagic fever with renal syndrome (hfrs) in the far east of russia, blood samples collected from hfrs patients in 1994-1998, were examined by reverse transcription-polymerase chain reaction. in addition, 36 sera were tested by an immunofluorescence assay for antibodies against hantaan, seoul, puumala, and khabarovsk viruses, and 54 samples were tested by plaque reduction neutralization test. with both serological assays, the highest antibody titers were t ... | 2000 | 11074123 |
serological analysis of hemorrhagic fever with renal syndrome (hfrs) patients in far eastern russia and identification of the causative hantavirus genotype. | hemorrhagic fever with renal syndrome (hfrs) is endemic in east asia and europe. the disease is caused by several viruses belonging to the genus hantavirus, including the hantaan virus (htnv), seoul virus (seov), dobrava belgrade virus (dobv), and puumala virus (puuv). recently, htnv-related viruses, amur (amr) and far east (fe) genotypes were identified as causative agents of hfrs in far eastern russia. to investigate the epidemiology of hfrs and virus transmission, we collected sera from 17 ac ... | 2003 | 12898330 |
[amplification test-systems in the diagnosis of hemorrhagic fever with renal syndrome and in studies of viral pathogens]. | the "vectohantivirus-ampli" test system based on rtpcr was shown as fitting the detection of virus rna in blood samples of patients with hemorrhagic fever with renal syndrome (hfrs) made at early stages and no later than 7 days from the disease onset. a sequence analysis of viral nucleotide sequences of pcr products produced by the test-system ensured the identification of hantaviruses (pathogens of hfrs). two genetic variants of puumula virus were shown to circulate in the territory of the bash ... | 2004 | 15455692 |
a comparative epidemiological study of hantavirus infection in japan and far east russia. | hantaviruses are causative agents of some severe human illnesses, including hemorrhagic fever with renal syndrome (hfrs) and hantavirus pulmonary syndrome (hps). the viruses are maintained by rodent hosts, and humans acquire infection by inhaling virus-contaminated excreta from infected animals. to examine the epidemiology of hantavirus infections in japan and far east russia, we conducted epidemiological surveys in these regions. in japan, anti-hantavirus antibodies were found in four rodent sp ... | 2007 | 17405352 |