| new enteroviruses, ev-93 and ev-94, associated with acute flaccid paralysis in the democratic republic of the congo. | surveillance of acute flaccid paralysis often identifies enteroviruses not typeable by virus neutralization in cell culture. during 2000 and 2001, 186 isolates from 138 children with acute flaccid paralysis in the democratic republic of the congo were sent for typing to the national reference centre for enteroviruses in lyon, france. the 5' utr of the viral genome could be amplified by pcr for 158 isolates from 114 patients. isolates from 89 patients were neutralizable, and contained non-polio e ... | 2007 | 17311342 |
| enterovirus 94, a proposed new serotype in human enterovirus species d. | the genus enterovirus (family picornaviridae) contains five species with strains isolated from humans: human enterovirus a (hev-a), hev-b, hev-c, hev-d and poliovirus. in this study, a proposed new serotype of hev-d was characterized. four virus strains were isolated from sewage in egypt and one strain from acute flaccid paralysis cases in the democratic republic of the congo. the complete genome of one environmental isolate, the complete coding sequence of one clinical isolate and complete vp1 ... | 2007 | 17325357 |
| cellular tropism of human enterovirus d species serotypes ev-94, ev-70, and ev-68 in vitro: implications for pathogenesis. | enterovirus 94 (ev-94) is an enterovirus serotype described recently which, together with ev-68 and ev-70, forms human enterovirus d species. this study investigates the seroprevalences of these three serotypes and their abilities to infect, replicate, and damage cell types considered to be essential for enterovirus-induced diseases. the cell types studied included human leukocyte cell lines, primary endothelial cells, and pancreatic islets. high prevalence of neutralizing antibodies against ev- ... | 2010 | 20872722 |