| detection of porcine circovirus 3 from captured wild boars in korea. | porcine circovirus 3 (pcv3) is a newly discovered ssdna virus. the virus was first reported in pigs suffering from several clinical syndromes, including porcine dermatitis and nephropathy syndrome, reproductive disorders, respiratory disease and myocarditis. pcv3 was recently reported in wild boars with high prevalence as well. in this study, 266 wild boar anal swab, feces, nasal swab and whole blood samples were collected from three mainland provinces and one island province (chungbuk, gangwon, ... | 2021 | 34057302 |
| porcine circovirus 3a field strains in free-living wild boars in paraná state, brazil. | porcine circovirus 3 (pcv-3) was identified in domestic pigs worldwide. although pcv-3 has also been detected in wild boars, information regarding its circulation in this free-living animal species is scarce. to investigate pcv-3 occurrence in free-living wild boars in brazil, 70 serum samples collected between january 2017 and june 2019 in paraná state, brazil were analyzed by pcr assay. amplicons measuring 330 bp in length were amplified in seven (10.0%) of the serum samples and confirmed to b ... | 2021 | 34073023 |
| identification of novel circovirus and anelloviruses from wolverines using a non-invasive faecal sampling approach. | viruses in the families circoviridae and anelloviridae have circular single-stranded dna genomes and have been identified in various animal species. some members of the circoviridae family such as beak and feather disease and porcine circovirus have been found to cause disease in their host animals. anelloviruses on the other hand have not been identified to cause disease in their hosts but are highly prevalent in mammalian species. using a non-invasive sampling approach, we identified novel cir ... | 2021 | 33992814 |
| current knowledge on porcine circovirus 3 (pcv-3): a novel virus with a yet unknown impact on the swine industry. | porcine circovirus 3 (pcv-3) is a recently described virus belonging to the family circoviridae. it represents the third member of genus circovirus able to infect swine, together with pcv-1, considered non-pathogenic, and pcv-2, one of the most economically relevant viruses for the swine worldwide industry. pcv-3 was originally found by metagenomics analyses in 2015 in tissues of pigs suffering from porcine dermatitis and nephropathy syndrome, reproductive failure, myocarditis and multisystemic ... | 2018 | 30631769 |
| detection of pcv3 in german wild boars. | porcine circovirus 3 is a newly described circovirus circulating worldwide. pcv3 may play an etiologic role in different pig diseases. two different genotypes of pcv3 were described, pcv3a and pcv3b. in order to analyse whether pcv3 is also present in wild boars, animals living in and near berlin were studied. the animals had been analysed previously and were found to form two genetically distinct and geographically coherent clusters. | 2019 | 30795772 |
| infection dynamics of porcine circovirus type 3 in longitudinally sampled pigs from four spanish farms. | porcine circovirus type 3 (pcv-3) is a recently discovered virus in domestic pigs and wild boar. the virus has been described in pigs with different clinical/pathological presentations and healthy animals, but the dynamics of infection is currently unknown. the aim of this study was to longitudinally monitor pcv-3 infection in 152 pigs from four different healthy farms (a, b, c and d) by means of pcr in serum. the selected animals were sampled five (farm a) or six (farms b-d) times from weaning ... | 2019 | 31040218 |
| transmission of porcine circovirus 3 (pcv3) by xenotransplantation of pig hearts into baboons. | porcine circovirus 3 (pcv3) is a newly described member of the virus family circoviridae. pcv3 is highly distributed among pigs and wild boars worldwide. a sudden introduction of pcv3 was recently observed in a herd of triple genetically modified pigs generated for xenotransplantation. these animals were used as donor pigs for orthotopic heart transplantation into baboons. in four cases, pcv3-positive hearts were transplanted, and transmission of pcv3 to the recipient was observed. pcv3 was foun ... | 2019 | 31315245 |
| genetic characterization of porcine circovirus 3 strains circulating in sardinian pigs and wild boars. | porcine circovirus 3 (pcv3) is a recently discovered member of the circoviridae family. so far, its presence has been reported in north america, asia, south america, and europe. in this study, blood and tissue samples from 189 sardinian suids (34 domestic pigs, 115 feral free ranging pigs, and 39 wild boars) were used to genetically characterize the pcv3 strains from sardinia. pcv3 infection in the animals was confirmed by real time pcr. the detection rate in the three groups analyzed was l7.64% ... | 2020 | 32370251 |
| lack of porcine circovirus 4 genome detection in pig samples from italy and spain. | the genus circovirus includes several species and mostly causes asymptomatic infections. porcine circovirus 2 (pcv-2) and, with increasing evidence, porcine circovirus 3 (pcv-3), have been associated with different clinical conditions all over the world. in 2019, a new porcine circovirus (pcv-4) was identified from diseased animals in china. because of the lessons learned from pcv-2 and pcv-3, it appears mandatory to investigate the actual distribution of this new virus and its potential associa ... | 2020 | 32486429 |
| complete genome characterization of porcine circovirus 3 recovered from wild boars in southern brazil. | in the present study, the complete nucleotide sequence of porcine circovirus 3 (pcv3) recovered from wild boars lymph nodes is described. the full genome was named pcv3-wb/br/rs and comprises 2,000 nucleotides with two open reading frames (orfs) with a stem-loop motif in intergenic region. the orfs are oriented in opposite directions and encode the putative capsid (cap) and replicase (rep) proteins. based on amino acid motif analysis, pcv3-wb/br/rs as well as most of the sequences from wild boar ... | 2020 | 32530113 |
| lack of evidence on the susceptibility of ticks and wild rodent species to pcv3 infection. | porcine circovirus 3 (pcv3) is an emerging virus, first detected in 2016 and widespread in the swine industry. although not considered a primary pathogen, pcv3 is potentially linked to several clinical conditions that threaten swine farming. wild boars are considered the main reservoir species for pcv3 infection in the wild, but recent detection in roe deer, chamois and associated ticks has complicated our understanding of its epidemiology. much emphasis has been placed on ticks, as competent ve ... | 2020 | 32825701 |
| recent progress on porcine circovirus type 3. | porcine circovirus 3 (pcv3) is a newly identified virus that belongs to the genus circovirus in the family circoviridae. since the first identification of pcv3 in domestic swine in 2016 in the usa, exciting progress on pcv3 has emphasized the importance of the virus. the aim of this review is to present recent advances in the molecular characteristics, epidemiology, and pathogenesis of pcv3. the virus spreads widely throughout almost all tissues of pig and wild boar in various countries, with a ... | 2019 | 31096019 |
| porcine circovirus 3 is highly prevalent in serum and tissues and may persistently infect wild boar (sus scrofa scrofa). | porcine circovirus 3 (pcv-3) prevalence has been minimally investigated in wild boar; dynamics of infection and viral tissue distribution are currently unknown. in this study, serum samples from 518 wild boar (from years 2004 to 2018) were used to study frequency of infection. also, serum samples from 19 boar captured and recaptured at least two times for a period of time from 1 month to 1 year were collected to determine pcv-3 infection dynamics. finally, to elucidate pcv-3 dna organic distribu ... | 2019 | 30091190 |
| a wild circulation: high presence of porcine circovirus 3 in different mammalian wild hosts and ticks. | porcine circovirus 3 (pcv-3) has emerged as a potential threat for swine industry, being consistently reported in the presence of several clinical signs all around the world. recently, its presence in wild boar has been demonstrated at high prevalence. this evidence is surprising since the lower density of wild populations might not be expected to sustain such efficient viral transmission. porcine circoviruses were proven to exhibit a certain plasticity in the host tropism and were detected in u ... | 2019 | 30901142 |
| an epidemiological investigation of porcine circovirus 3 infection in cattle in shandong province, china. | porcine circovirus type 3 (pcv3) is a single-stranded, closed circular dna virus, which causes porcine dermatitis and nephropathy syndrome (pdns), multisystemic inflammation, and reproductive failure. the present study aimed to investigate the seroprevalence of pcv3 in cattle (bos taurus) in shandong province, china, and examine its genome diversity. | 2019 | 30760271 |
| detection of porcine circovirus 3 in wildlife species in spain. | porcine circovirus 3 (pcv-3) is the third member of the family circoviridae, genus circovirus, able to infect swine. a high prevalence of viral dna has been recorded in wild boars. recently, pcv-3 dna was identified in italian wild ruminants. based on these previous results, this study assessed the frequency of pcv-3 dna detection in free-ranging ruminants and lagomorpha species in spain. in addition, the genetic characterization of the pcv-3 pcr-positive samples was performed. a total of 801 se ... | 2020 | 32369945 |