| coexistence of several novel hantaviruses in rodents indigenous to north america. | three genetically distinct members of the hantavirus genus have been detected in nevada rodents by rt-pcr and nucleotide sequence analysis. these include sin nombre (sn), el moro canyon (elmc), and prospect hill (ph)-like viruses which are primarily associated with peromyscus maniculatus (deer mouse), reithrodontomys megalotis (western harvest mouse), and microtus spp. (voles), respectively. although this region of the united states is ecologically diverse, rodents infected with different hantav ... | 1995 | 7483255 |
| nucleotide sequence analysis of the m genomic segment of el moro canyon hantavirus: antigenic distinction from four corners hantavirus. | el moro canyon hantavirus (elmc, previously known as hmv-1) is associated with the western harvest mouse reithrodontomys megalotis. the interpretation that elmc is a novel hantavirus was based upon comparisons of the nucleotide sequence of the s genomic segment with those of other hantaviruses. we now show that the elmc m genome, like the s genome, is genetically similar to but distinct from that of four corners hantavirus (fc). the elmc m genome is 3801 nt in length and encodes a glycoprotein p ... | 1995 | 7544047 |
| nucleotide sequence analysis of the m genomic segment of el moro canyon hantavirus: antigenic distinction from four corners hantavirus. | el moro canyon hantavirus (elmc, previously known as hmv-1) is associated with the western harvest mouse reithrodontomys megalotis. the interpretation that elmc is a novel hantavirus was based upon comparisons of the nucleotide sequence of the s genomic segment with those of other hantaviruses. we now show that the elmc m genome, like the s genome, is genetically similar to but distinct from that of four corners hantavirus (fc). the elmc m genome is 3801 nt in length and encodes a glycoprotein p ... | 1995 | 7544047 |
| prevalence and geographic genetic variation of hantaviruses of new world harvest mice (reithrodontomys): identification of a divergent genotype from a costa rican reithrodontomys mexicanus. | we recently described a novel hantavirus (hmv-1) of the western harvest mouse reithrodontomys megalotis. screening of 181 additional specimens of reithrodontomys from the united states and mexico, including samples of r. mexicanus, r. sumichrasti, and r. gracilis of costa rica, for antibodies to hantavirus nucleocapsid protein revealed a widespread enzootic of hantavirus infection. genetic analyses of 7 s genomes of reithrodontomys-associated hantaviruses demonstrated that the enzootic of hmv-1 ... | 1995 | 7886948 |
| genetic identification of a novel hantavirus of the harvest mouse reithrodontomys megalotis. | we have cloned the s genomic segment of a novel hantavirus of the harvest mouse reithrodontomys megalotis. the virus is phylogenetically distinct from other hantaviruses. the new hantavirus was identified in harvest mice separated by approximately 1,000 km. a wood rat (neotoma mexicana) was found to be infected with the harvest mouse hantavirus. | 1994 | 8084007 |
| genetic identification of a novel hantavirus of the harvest mouse reithrodontomys megalotis. | we have cloned the s genomic segment of a novel hantavirus of the harvest mouse reithrodontomys megalotis. the virus is phylogenetically distinct from other hantaviruses. the new hantavirus was identified in harvest mice separated by approximately 1,000 km. a wood rat (neotoma mexicana) was found to be infected with the harvest mouse hantavirus. | 1994 | 8084007 |
| cocirculation of multiple hantaviruses in texas, with characterization of the small (s) genome of a previously undescribed virus of cotton rats (sigmodon hispidus). | an environmental and laboratory investigation was conducted after a fatal childhood case of hantavirus pulmonary syndrome occurred in deaf smith county, texas in may 1995. a trapping campaign was conducted to identify possible rodent carriers. six species of murid and heteromyid rodents were collected, and at least one hantavirus-seropositive specimen was found in each of the five murid species. tissues from a selection of 11 seropositive specimens were examined by the polymerase chain reaction ... | 1996 | 9025697 |
| cocirculation of multiple hantaviruses in texas, with characterization of the small (s) genome of a previously undescribed virus of cotton rats (sigmodon hispidus). | an environmental and laboratory investigation was conducted after a fatal childhood case of hantavirus pulmonary syndrome occurred in deaf smith county, texas in may 1995. a trapping campaign was conducted to identify possible rodent carriers. six species of murid and heteromyid rodents were collected, and at least one hantavirus-seropositive specimen was found in each of the five murid species. tissues from a selection of 11 seropositive specimens were examined by the polymerase chain reaction ... | 1996 | 9025697 |
| hantavirus (bunyaviridae) infections in rodents from orange and san diego counties, california. | during a screening program to determine the extent of hantavirus activity in orange and san diego counties, california, serum samples from 2,365 rodents representing nine genera and 15 species were tested for hantavirus antibodies. a reverse transcription-polymerase chain reaction on selected seropositive rodents was used to identify the specific hantavirus. rodents positive for sin nombre virus (snv) antibodies by western blot included 86 (9.1%) of 948 deer mice (peromyscus maniculatus), four ( ... | 1999 | 9988327 |
| hantavirus (bunyaviridae) infections in rodents from orange and san diego counties, california. | during a screening program to determine the extent of hantavirus activity in orange and san diego counties, california, serum samples from 2,365 rodents representing nine genera and 15 species were tested for hantavirus antibodies. a reverse transcription-polymerase chain reaction on selected seropositive rodents was used to identify the specific hantavirus. rodents positive for sin nombre virus (snv) antibodies by western blot included 86 (9.1%) of 948 deer mice (peromyscus maniculatus), four ( ... | 1999 | 9988327 |
| epizootiology of sin nombre and el moro canyon hantaviruses, southeastern colorado, 1995-2000. | sin nombre virus (snv) is an etiologic agent of hantavirus pulmonary syndrome. to better understand the natural history of this virus we studied population dynamics and temporal pattern of infection of its rodent hosts in southeastern colorado (usa) from 1995 to 2000. we present evidence for the presence of two hantaviruses, snv in deer mice (peromyscus maniculatus) and el moro canyon virus in western harvest mice (reithrodontomys megalotis), at our study sites. sin nombre virus appeared only sp ... | 2005 | 15827206 |
| epizootiology of sin nombre and el moro canyon hantaviruses, southeastern colorado, 1995-2000. | sin nombre virus (snv) is an etiologic agent of hantavirus pulmonary syndrome. to better understand the natural history of this virus we studied population dynamics and temporal pattern of infection of its rodent hosts in southeastern colorado (usa) from 1995 to 2000. we present evidence for the presence of two hantaviruses, snv in deer mice (peromyscus maniculatus) and el moro canyon virus in western harvest mice (reithrodontomys megalotis), at our study sites. sin nombre virus appeared only sp ... | 2005 | 15827206 |
| genetic diversity of hantaviruses in mexico: identification of three novel hantaviruses from neotominae rodents. | a variety of hantaviruses are harbored by rodents in north and south america, some of which can cause hantavirus pulmonary syndrome. to obtain greater evolutionary insight into hantaviruses in the americas, a total of 211 rodents were captured in the mexican states of guerrero and morelos in 2006. anti-hantavirus antibodies were detected in 27 of 211 serum samples (12.8%) by elisa. the distribution of seropositive rodents was: 17 peromyscus beatae, 1 megadontomys thomasi, 1 neotoma picta, 6 reit ... | 2011 | 22138671 |
| oncornavirus expression in human x mouse hybrid cells segregating mouse chromosomes. | human x mouse hybrid clones obtained by fusing transformed human (va2) cells with embryonic mouse brain cells were tested for their ability to spontaneously express type c virus particles. it had been previously shown that these hybrid cells preferentially retained human chromosomes while mouse chromosomes were lost. the culture fluid from one cell line was found to contain type c particle markers in abundance, and typical budding c particles were observed in the cells by electron microscopy. in ... | 1974 | 4366059 |
| biological properties of a type c virus isolated from a human x mouse hybrid cell line. | the biological properties of the hmv-1 virus, spontaneously released from a human x c57bl/6 mouse hybrid cell line, were similar to those of radlv, the prototype b-tropic virus of c57bl/6 mice. both viruses replicated on b-type mouse cells and in the wild mouse cell line sc-1. the plaque-forming abilities of the two viruses were relatively low, but gradually increased after passage in new host cells. both viruses were neutralized by akr antisera but not by fmr antisera. hmv-1 virus could rescue ... | 1975 | 49896 |
| geographic distribution of hantaviruses associated with neotomine and sigmodontine rodents, mexico. | to increase our knowledge of the geographic distribution of hantaviruses associated with neotomine or sigmodontine rodents in mexico, we tested 876 cricetid rodents captured in 18 mexican states (representing at least 44 species in the subfamily neotominae and 10 species in the subfamily sigmodontinae) for anti-hantavirus igg. we found antibodies against hantavirus in 35 (4.0%) rodents. nucleotide sequence data from 5 antibody-positive rodents indicated that sin nombre virus (the major cause of ... | 2012 | 22469569 |