| sunday canyon virus, a new ungrouped agent from the tick argas (a.) cooleyi in texas. | a new arbovirus was isolated from texas, u.s.a., populations of the cliff swallow parasits argas (argas) cooleyi kohls and hoogstraal, 1960. the virus, named sunday canyon, is serological urelated to any of 185 arbovirus strains or 20 other viral agents with which it was compared. morphologically it resembles bunyamwera viruses and, in common with them, is sensitive to lipid solvents and acid ph, and apparently possesses rna. although considerably resistant to a temperature of 41.5 degrees c, it ... | 1977 | 15436 |
| nucleotide sequence analysis of the large (l) genomic rna segment of bunyamwera virus, the prototype of the family bunyaviridae. | the complete nucleotide sequence of the large (l) genome segment of bunyamwera virus has been determined from overlapping cdna clones. the segment is 6875 nucleotides long and has a base composition of 29.8% a, 17.9% c, 15.4% g, and 36.9% u. eighteen of the terminal 19 nucleotides at the 3' and 5' ends are complementary. in the viral-complementary (+ sense) rna there is a single long open reading frame (orf) from aug at bases 51-53 to a uag stop codon at bases 6765-6767; this orf encodes a polyp ... | 1989 | 2596023 |
| nucleotide sequence of the m segment of germiston virus: comparison of the m gene product of several bunyaviruses. | the complete nucleotide sequence of the m rna segment of germiston bunyavirus was determined from plasmids containing overlapping m cdna inserts. the m segment is 4534 nucleotides long and contains a 50-base-long inverted terminal repeat which can form a stable hydrogen-bonded secondary structure with a delta g of -45.8 kcal/mol. the rna molecule complementary to viral rna contains a single large open reading frame that encodes a 1437 amino acid-long protein with hydrophobic amino and carboxy te ... | 1988 | 3176688 |
| nucleotide sequence of the bunyamwera virus m rna segment: conservation of structural features in the bunyavirus glycoprotein gene product. | the complete nucleotide sequence of the bunyamwera virus m rna segment was determined from four overlapping cdna clones and by primer extension. the rna segment is 4458 bases in length, and encodes a single gene product in the viral complementary rna. the predicted protein is 1433 amino acids long (mol wt 162,065), contains four potential glycosylation sites, and is relatively cysteine rich. it is presumed that the three proteins g1, g2, and nsm which have been mapped to the m rna segment are sy ... | 1986 | 3753629 |
| experimental infection of monkeys with bunyamwera and germiston viruses. | clinical and serological responses investigated in rhesus and cynomolgus monkeys infected with either bunyamwera or germiston viruses were generally minimal or absent. a febrile reaction occurred in one of eight monkeys, and another monkey died unexplainably among those given bunyamwera virus. all monkeys infected with germiston virus by subcutaneous, intravenous, or intracerebral routes developed fevers, and all infections were relatively consistent in time of onset, duration, and level of vire ... | 1970 | 16557913 |
| infection by bunyamwera virus (orthobunyavirus) in free ranging birds of cordoba city (argentina). | infection by bunyamwera virus (bunv) species (family bunyaviridae, genus orthobunyavirus) has been detected in ewes, goats, cows, horses and humans all the way through america. however, there are no evidences of such infection in birds. to detect bunv (cbaar-426) infection in free ranging birds, a serological survey was carried out in córdoba city between 2004 and 2005. birds of 13 families presented neutralizing antibodies against bunv (cbaar-426), showing an increase in the seroprevalence from ... | 2009 | 19501478 |
| interferon-stimulated gene (isg)-expression screening reveals the specific antibunyaviral activity of isg20. | bunyaviruses pose a significant threat to human health, prosperity, and food security. in response to viral infections, interferons (ifns) upregulate the expression of hundreds of interferon-stimulated genes (isgs), whose cumulative action can potently inhibit the replication of bunyaviruses. we used a flow cytometry-based method to screen the ability of ∼500 unique isgs from humans and rhesus macaques to inhibit the replication of bunyamwera orthobunyavirus (bunv), the prototype of both the per ... | 2018 | 29695422 |
| association of batai virus infection and encephalitis in harbor seals, germany, 2016. | we isolated batai virus from the brain of a euthanized, 26-year-old, captive harbor seal with meningoencephalomyelitis in germany. we provide evidence that this orthobunyavirus can naturally infect the central nervous system of a mammal. the full-genome sequence showed differences from a previously reported virus isolate from a mosquito in germany. | 2018 | 30124416 |