| vinblastine and diethylstilboestrol tested in the in vitro mammalian cell micronucleus test (mnvit) at swansea university uk in support of oecd draft test guideline 487. | the known aneugens vinblastine and diethylstilboestrol (des) were tested in the in vitro micronucleus assay, with and without cytokinesis block in chinese hamster cho cells, at the laboratories of swansea university, swansea, uk. these experiments were carried out to determine the suitability of the cell death and cytostasis measures used in the assay, as recommended in the draft oecd test guideline 487, 2007. both compounds were positive in the assay without cytokinesis block at concentrations ... | 2010 | 19666138 |