| snake venomics and antivenomics of bothrops atrox venoms from colombia and the amazon regions of brazil, perú and ecuador suggest the occurrence of geographic variation of venom phenotype by a trend towards paedomorphism. | the venom proteomes of bothrops atrox from colombia, brazil, ecuador, and perú were characterized using venomic and antivenomic strategies. our results evidence the existence of two geographically differentiated venom phenotypes. the venom from colombia comprises at least 26 different proteins belonging to 9 different groups of toxins. pi-metalloproteinases and k49-pla(2) molecules represent the most abundant toxins. on the other hand, the venoms from brazilian, ecuadorian, and peruvian b. atrox ... | 2009 | 19665598 |