| primers of glycosaminoglycan biosynthesis from peruvian rain forest plants. | we have developed a rapid, high throughput screening assay for compounds that alter the assembly of glycosaminoglycan chains in chinese hamster ovary cells. the assay uses autoradiography to measure the binding of newly synthesized [35s]proteoglycans and [35s]glycosaminoglycans to a positively charged membrane. screening over 1000 extracts from a random plant collection obtained from the amazon rain forest yielded five plants that stimulated glycosaminoglycan assembly in both wild-type cells and ... | 1998 | 9712841 |