Publications

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detection and molecular characterization of foamy viruses in central african chimpanzees of the pan troglodytes troglodytes and pan troglodytes vellerosus subspecies.foamy viruses are exogenous retroviruses that are highly endemic in non-human primates (nhps). recent studies, mainly performed in north america, indicated frequent simian foamy virus (sfv) infection in persons occupationally exposed to nhps. this zoonotic infection was demonstrated mainly after bites by chimpanzees [pan troglodytes (p. t.)] of the west african p. t. verus subspecies in primatology centers or zoos in the usa.200616556292
a new bacillus anthracis found in wild chimpanzees and a gorilla from west and central africa. 200616738706
human immunodeficiency viruses: siv infection in wild gorillas.chimpanzees (pan troglodytes troglodytes) from west central africa are recognized as the reservoir of simian immunodeficiency viruses (sivcpzptt) that have crossed at least twice to humans: this resulted in the aids pandemic (from human immunodeficiency virus hiv-1 group m) in one instance and infection of just a few individuals in cameroon (by hiv-1 group n) in another. a third hiv-1 lineage (group o) from west central africa also falls within the sivcpzptt radiation, but the primate reservoir ...200617093443
genetic diversity and phylogeographic clustering of sivcpzptt in wild chimpanzees in cameroon.it is now well established that the clade of simian immunodeficiency viruses (sivs) infecting west central african chimpanzees (pan troglodytes troglodytes) and western gorillas (gorilla gorilla gorilla) comprises the progenitors of human immunodeficiency virus type 1 (hiv-1). in this study, we have greatly expanded our previous molecular epidemiological survey of sivcpz in wild chimpanzees in cameroon. the new results confirm a wide but uneven distribution of sivcpzptt in p. t. troglodytes thro ...200717651775
origin and biology of simian immunodeficiency virus in wild-living western gorillas.western lowland gorillas (gorilla gorilla gorilla) are infected with a simian immunodeficiency virus (sivgor) that is closely related to chimpanzee and human immunodeficiency viruses (sivcpz and hiv-1, respectively) in west central africa. although existing data suggest a chimpanzee origin for sivgor, a paucity of available sequences has precluded definitive conclusions. here, we report the molecular characterization of one partial (bq664) and three full-length (cp684, cp2135, and cp2139) sivgor ...200919073717
characterization of enteroviruses from non-human primates in cameroon revealed virus types widespread in humans along with candidate new types and species.enteroviruses (evs) infecting african non-human primates (nhp) are still poorly documented. this study was designed to characterize the genetic diversity of evs among captive and wild nhp in cameroon and to compare this diversity with that found in humans. stool specimens were collected in april 2008 in nhp housed in sanctuaries in yaounde and neighborhoods. moreover, stool specimens collected from wild nhp from june 2006 to october 2008 in the southern rain forest of cameroon were considered. r ...201425079078
origin of the hiv-1 group o epidemic in western lowland gorillas.hiv-1, the cause of aids, is composed of four phylogenetic lineages, groups m, n, o, and p, each of which resulted from an independent cross-species transmission event of simian immunodeficiency viruses (sivs) infecting african apes. although groups m and n have been traced to geographically distinct chimpanzee communities in southern cameroon, the reservoirs of groups o and p remain unknown. here, we screened fecal samples from western lowland (n = 2,611), eastern lowland (n = 103), and mountai ...201525733890
why are nigeria-cameroon chimpanzees (pan troglodytes ellioti) free of sivcpz infection?simian immunodeficiency virus (siv) naturally infects two subspecies of chimpanzee: pan troglodytes troglodytes from central africa (sivcpzptt) and p. t. schweinfurtii from east africa (sivcpzpts), but is absent in p. t. verus from west africa and appears to be absent in p. t. ellioti inhabiting nigeria and western cameroon. one explanation for this pattern is that p. t. troglodytes and p. t schweinfurthii may have acquired sivcpz after their divergence from p. t. verus and p. t. ellioti. howeve ...201627505066
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