Publications

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detection and molecular characterization of foamy viruses in central african chimpanzees of the pan troglodytes troglodytes and pan troglodytes vellerosus subspecies.foamy viruses are exogenous retroviruses that are highly endemic in non-human primates (nhps). recent studies, mainly performed in north america, indicated frequent simian foamy virus (sfv) infection in persons occupationally exposed to nhps. this zoonotic infection was demonstrated mainly after bites by chimpanzees [pan troglodytes (p. t.)] of the west african p. t. verus subspecies in primatology centers or zoos in the usa.200616556292
why are nigeria-cameroon chimpanzees (pan troglodytes ellioti) free of sivcpz infection?simian immunodeficiency virus (siv) naturally infects two subspecies of chimpanzee: pan troglodytes troglodytes from central africa (sivcpzptt) and p. t. schweinfurtii from east africa (sivcpzpts), but is absent in p. t. verus from west africa and appears to be absent in p. t. ellioti inhabiting nigeria and western cameroon. one explanation for this pattern is that p. t. troglodytes and p. t schweinfurthii may have acquired sivcpz after their divergence from p. t. verus and p. t. ellioti. howeve ...201627505066
origin and biology of simian immunodeficiency virus in wild-living western gorillas.western lowland gorillas (gorilla gorilla gorilla) are infected with a simian immunodeficiency virus (sivgor) that is closely related to chimpanzee and human immunodeficiency viruses (sivcpz and hiv-1, respectively) in west central africa. although existing data suggest a chimpanzee origin for sivgor, a paucity of available sequences has precluded definitive conclusions. here, we report the molecular characterization of one partial (bq664) and three full-length (cp684, cp2135, and cp2139) sivgor ...200919073717
genetic diversity and phylogeographic clustering of sivcpzptt in wild chimpanzees in cameroon.it is now well established that the clade of simian immunodeficiency viruses (sivs) infecting west central african chimpanzees (pan troglodytes troglodytes) and western gorillas (gorilla gorilla gorilla) comprises the progenitors of human immunodeficiency virus type 1 (hiv-1). in this study, we have greatly expanded our previous molecular epidemiological survey of sivcpz in wild chimpanzees in cameroon. the new results confirm a wide but uneven distribution of sivcpzptt in p. t. troglodytes thro ...200717651775
human immunodeficiency viruses: siv infection in wild gorillas.chimpanzees (pan troglodytes troglodytes) from west central africa are recognized as the reservoir of simian immunodeficiency viruses (sivcpzptt) that have crossed at least twice to humans: this resulted in the aids pandemic (from human immunodeficiency virus hiv-1 group m) in one instance and infection of just a few individuals in cameroon (by hiv-1 group n) in another. a third hiv-1 lineage (group o) from west central africa also falls within the sivcpzptt radiation, but the primate reservoir ...200617093443
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