| ophthalmological results from a placebo controlled comparative 3-dose ivermectin study in the treatment of onchocerciasis. | one hundred and ninety eight patients with moderate to heavy infection with onchocerca volvulus and with eye involvement in most, were allocated randomly to treatment with 100, 150 or 200 mcg/kg body weight of ivermectin or placebo given as a single oral dose in a double-blind dose finding study. the patients were drawn from an area under over ten years of vector control in northern ghana by the onchocerciasis control programme, ocp. they underwent detailed clinical, laboratory and ophthalmologi ... | 1989 | 2694314 |
| the chemotherapy of onchocerciasis. xiii. studies with ivermectin in onchocerciasis patients in northern ghana, a region with long lasting vector control. | one hundred and ninety eight patients with moderate to heavy infections with onchocerca volvulus were randomly assigned to receive single doses of 100, 150 or 200 mcg/kg of ivermectin or matching placebo capsules. detailed systemic, ocular and parasitological examinations were carried out at intervals over a period of one year. nodules were excised twelve months after treatment to evaluate the effect of the treatment with ivermectin in adult o. volvulus. the three ivermectin-treated groups produ ... | 1989 | 2694315 |
| deforestation and the spatio-temporal distribution of savannah and forest members of the simulium damnosum complex in southern ghana and south-western togo. | spatio-temporal data on cytotaxonomic identifications of larvae of different members of the simulium damnosum complex collected from rivers in southern ghana and south-western togo from 1975 until 1997 were analysed. when the data were combined, the percentages of savannah blackflies (s. damnosum sensu stricto and s. sirbanum) in the samples were shown to have been progressively increasing since 1975. the increases were statistically significant (p < 0.001), but the rates of increase were not li ... | 2002 | 12625139 |