Publications

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observations on the morphology of adults and larval stages of oesophagostomum sp. isolated from man in northern togo and ghana.infection with oesophagostomum sp. appears to be extremely common in man in northern togo and ghana. adult specimens were recovered from the intestinal lumen by treatment with pyrantel pamoate and the morphological characteristics of oesophagostomes of man could for the first time be compared with information available on the morphology of oesophagostomes of monkeys. the observations and measurements demonstrated that the species involved is oesophagostomum bifurcum and that the eggs of this spe ...19938509618
the capacity of the third-stage larvae of oesophagostomum bifurcum to survive adverse conditions.human infections with the intestinal nematode oesophagostomum bifurcum are commonly found in the sudan savannah of northern togo and ghana. apparently, the long and hot dry season in this region does not prevent transmission, which is believed to take place through ingestion of the infective, third-stage larvae (l3). oesophagostomum l3 cultured from human stools, unlike the larvae of necator americanus, were shown to survive desiccation. in addition, 93% of the o. bifurcum l3 frozen for 24 h at ...200010827871
the role of pigs as transport hosts of the human helminths oesophagostomum bifurcum and necator americanus.we conducted a study in an endemic area of both oesophagostomum bifurcum and necator americanus in northern ghana to examine the possibility of pigs acting as transport hosts for these two human helminth species, due to the commonly observed coprophagic habits of pigs. under controlled conditions four parasite-free pigs consumed fresh faeces from people heavily infected with both helminths, and faeces were subsequently collected from the rectum of the pigs from 5 to 50 h post-feeding. four to fi ...200010936571
determining the prevalence of oesophagostomum bifurcum and necator americanus infections using specific pcr amplification of dna from faecal samples.until recently infection of humans with oesophagostomum bifurcum was regarded as a rare zoonosis. but in northern togo and ghana its prevalence is 50% or more in certain villages. diagnosis is hampered by the fact that the eggs of o. bifurcum are morphologically identical to those of the hookworm necator americanus. stools have to be cultured for 7 days to allow eggs to hatch to the characteristic third-stage (l3) larvae. we evaluated the applicability of specific polymerase chain reactions (pcr ...200111555440
polymerase chain reaction-based differential diagnosis of ancylostoma duodenale and necator americanus infections in humans in northern ghana.we evaluated a two-step semi-nested polymerase chain reaction (pcr)-based approach for the specific detection of ancylostoma duodenale dna in human faeces. the test was used to determine to what extent this species of hookworm is present in the regions of bolgatanga and garu of northern ghana. initially, the sensitivity and specificity of the pcr were tested using a range of well-defined control samples. subsequently, a total of 378 human faecal dna samples from bolgatanga and garu were subjecte ...200515941421
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