| trials of oral bovine and rhesus rotavirus vaccines in finland: a historical account and present status. | live oral rotavirus vaccine strain rit 4237, derived from group a bovine rotavirus ncdv, was given to human volunteers in tampere, finland in 1982. efficacy studies of this vaccine in 6-12 month-old children gave results characteristic of the performance of oral rotavirus vaccines in general: 58% protective efficacy against any rotavirus gastroenteritis and 82% against "clinically significant" gastroenteritis. four trials of rit 4237 bovine rotavirus vaccine, one trial of group a rrv-1 rhesus ro ... | 1996 | 9015114 |
| highly divergent neurovirulent vaccine-derived polioviruses of all three serotypes are recurrently detected in finnish sewage. | in finland, surveillance of potential re-emergence of poliovirus transmission is mainly based on environmental surveillance, i.e. search for infectious poliovirus in sewage samples. since december 2008, 21 genetically highly divergent, neurovirulent vaccine-derived polioviruses (vdpv) have been isolated from sewage in tampere, finland. while the source of the vdpv is unknown, characteristics of the viruses resemble those of strains isolated from immunodeficient, persistently infected persons. no ... | 2010 | 20483108 |