| occurrence of paracoccidioides lutzii in the amazon region: description of two cases. | paracoccidioidomycosis (pcm), the most important human systemic mycosis in latin america, is known to be caused by at least four different phylogenetic lineages within the paracoccidioides brasiliensis complex, including s1, ps2, ps3, and pb01-like group. herein, we describe two cases of pcm in patients native from the amazon region. the disease was originally thought to have been caused by p. brasiliensis. despite the severity of the cases, sera from the patients were negative in immunodiffusio ... | 2012 | 22927496 |
| paracoccidioidomycosis in a western brazilian amazon state: clinical-epidemiologic profile and spatial distribution of the disease. | paracoccidioidomycosis (pcm) is a systemic infection caused by the fungus paracoccidioides brasiliensis. pcm is considered one of the most important systemic mycoses in latin america. | 2014 | 24603739 |
| activity of compounds isolated from baccharis dracunculifolia d.c. (asteraceae) against paracoccidioides brasiliensis. | paracoccidioidomycosis is a prevalent systemic mycosis in latin america which requires prolonged treatment with highly toxic antifungals. baccharis dracunculifolia is a medicinal plant in brazil that is a candidate in the search for new drugs. fractions of the hexanic extracts were obtained using chromatographic procedures and assessed using an antifungal assay with paracoccidioides brasiliensis (pb18), tumor cell lines and amastigote forms of leishmania, l. amazonensis. four compounds were isol ... | 2012 | 22548242 |
| early diagnosis and prompt treatment by surgery in jorge lobo's disease (keloidal blastomycosis). | in 1931 the brazilian doctor jorge lobo examined a patient from the amazon basin who had nodular confluent skin lesions over the lumbosacral region and encountered a new fungus pathogenic for man paracoccidioides loboi. this classification was based on the morphological aspect of the parasite which was very similar to paracoccidioides brasiliensis the causative agent of a systemic mycosis paracoccidioidomycosis or south american blastomycosis. other authors use the name loboa loboi. the final de ... | 1981 | 7242649 |
| paracoccidioides brasiliensis-reactive antibodies in brazilian blood donors. | in a survey for primary paracoccidioidomycosis (pcm) infection (and not the clinical disease), two groups of blood donors were analyzed. one study group was drawn from donors living in a rural area where pcm is endemic, and the other group from urban residents of a large city, são paulo. anti-paracoccidioides brasiliensis (pb) specific antibodies (igg) in sera were analyzed by elisa, using crude pb exoantigens (exoag) and purified specific pb 43 kda glycoprotein (gp43). the results showed that 2 ... | 2002 | 12230218 |