| characterization of hiv drug resistance mutations among patients failing first-line antiretroviral therapy from a tertiary referral center in lusaka, zambia. | in settings of resource constraint, an understanding of hiv drug resistance can guide antiretroviral therapy (art) at switch to second-line therapy. to determine the prevalence of such hiv drug resistance mutations (hiv drm), we used an in-house sequencing assay in the pol gene (protease and partial reverse transcriptase) in a cohort of patients suspected of failing a first-line regimen, which in zambia comprises two nucleoside/nucleotide reverse transcriptase inhibitors (nrtis) and one non-nucl ... | 2015 | 25754408 |