Publications

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croi 2017: advances in antiretroviral therapy.the 2017 conference on retroviruses and opportunistic infections (croi) featured exciting preclinical data on investigational antiretroviral agents with good in vitro efficacy and long half-lives. investigational medications, including bictegravir, demonstrated excellent efficacy and tolerability, as did dual-agent therapy with dolutegravir paired with rilpivirine or with lamivudine. dolutegravir monotherapy proved inadvisable due to virologic failure and resistance. the gap between high- and lo ...201728598790
suspected female-to-male sexual transmission of zika virus - new york city, 2016.a routine investigation by the new york city (nyc) department of health and mental hygiene (dohmh) identified a nonpregnant woman in her twenties who reported she had engaged in a single event of condomless vaginal intercourse with a male partner the day she returned to nyc (day 0) from travel to an area with ongoing zika virus transmission. she had headache and abdominal cramping while in the airport awaiting return to nyc. the following day (day 1) she developed fever, fatigue, a maculopapular ...201627442327
zika virus testing considerations: lessons learned from the first 80 real-time reverse transcription-pcr-positive cases diagnosed in new york state.the performance and interpretation of laboratory tests for zika virus (zkv) continue to be evaluated. serology is cross-reactive, laborious, and frequently difficult to interpret, and serum was initially solely recommended for molecular diagnosis. zkv testing was initiated in january 2016 in new york state for symptomatic patients, pregnant women, their infants, and patients with guillain-barré syndrome who had traveled to areas with zkv transmission. subsequently, eligibility was expanded to pr ...201727927917
using a call center to coordinate zika virus testing-new york city, 2016.after local testing criteria for zika virus expanded to include asymptomatic pregnant women who traveled to areas with active zika virus transmission while pregnant, the new york city (nyc) department of health and mental hygiene (dohmh) experienced a surge in test requests and subsequent testing delays due to factors such as incorrectly completed laboratory requisition forms. the authors describe how dohmh addressed these issues by establishing the zika testing call center (ztcc).201728101877
prevalence and clinical attributes of congenital microcephaly - new york, 2013-2015.congenital zika virus infection can cause microcephaly and other severe fetal neurological anomalies (1). to inform microcephaly surveillance efforts and assess ascertainment sources, the new york state department of health and the new york city department of health and mental hygiene sought to determine the prevalence of microcephaly in new york during 2013-2015, before known importation of zika virus infections. suspected newborn microcephaly diagnoses were identified from 1) reports submitted ...201728182608
preparedness for zika virus disease - new york city, 2016.the rapid spread of zika virus across the world health organization's region of the americas has had a direct effect on the u.s. health care delivery system. hospitals in new york city (nyc) have been implementing prevention and response efforts consistent with cdc guidance. as of september 21, 2016, a total of 715 cases of laboratory-confirmed zika virus disease had been diagnosed in new york state among travelers who returned from affected areas, their sexual contacts, or infants infected in u ...201627787490
quantifying the potential pathways and locations of rift valley fever virus entry into the united states.the global invasion of west nile virus, chikungunya virus and zika virus in the past two decades suggests an increasing rate of mosquito-borne virus (arbovirus) dispersal. rift valley fever virus (rvfv) is an arbovirus identified as a high-consequence threat to the united states (usa) because of the severe economic and health consequences associated with disease. numerous studies demonstrate that the usa is receptive to rvfv transmission based on the widespread presence of competent mosquito spe ...201728191786
probable zika virus-associated guillain-barré syndrome: challenges with clinico-laboratory diagnosis.a 55year old woman in new york city presented in may 2016 with progressive weakness, ataxia, paresthesia, and areflexia, shortly after returning from the dominican republic. lumbar puncture revealed cytoalbuminological dissociation. due to her recent travel, zika-associated guillain barré syndrome (gbs) was suspected and she underwent evaluation for recent flavivirus exposure. zika virus rna was not detected in serum, but zika virus immunoglobulin m (igm) was detected in both serum and cerebrosp ...201728320169
zika virus knowledge among pregnant women who were in areas with active transmission.we surveyed women in new york, new york, usa, who were in areas with active zika virus transmission while pregnant. of 99 women who were us residents, 30 were unaware of the government travel advisory to areas with active zika virus transmission while pregnant, and 37 were unaware of their pregnancies during travel.201727855041
a survey of the knowledge, attitudes and practices on zika virus in new york city.over 900 travel-associated zika virus cases have been identified in new york city (nyc), new york. a survey was administered in nyc adapted from the knowledge, attitudes, and practices (kap) survey on zika virus developed by the world health organization (who).201829291723
[arboviruses also have an american dream].some arboviruses that originated in the old world have been introduced by humans into the american continent. the first of them was the yellow fever virus, coming from the west african coast with slaves in the 17th-19th centuries, followed by dengue viruses, which were always prevalent within the americas. next was thewest nile virus, introduced in new york in 1999, that spread in only a few years over the whole continent. then, chikungunya virus arrived on saint martin island in 2013 after its ...201728509947
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