| metagenomics of two severe foodborne outbreaks provides diagnostic signatures and signs of coinfection not attainable by traditional methods. | diagnostic testing for foodborne pathogens relies on culture-based techniques that are not rapid enough for real-time disease surveillance and do not give a quantitative picture of pathogen abundance or the response of the natural microbiome. powerful sequence-based culture-independent approaches, such as shotgun metagenomics, could sidestep these limitations and potentially reveal a pathogen-specific signature on the microbiome that would have implications not only for diagnostics but also for ... | 2017 | 27881416 |
| epidemic salmonellosis from cheddar cheese: surveillance and prevention. | on august 3, 1976, ongoing salmonella surveillance in colorado first detected an epidemic of salmonella heidelberg infections that eventually totaled 339 isolates. the majority of the cases occurred between july 23 and august 12 in two widely separated cities: denver and pueblo. epidemiologic investigation successively incriminated 1) recent dining at mexican-style restaurants (p less than 0.001), 2) eating foods containing cheese in these restaurants (p = 0.029), and 3) consumption of cheddar c ... | 1980 | 7355885 |