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isolation and characterization of porcine deltacoronavirus from pigs with diarrhea in the united states.porcine deltacoronavirus (pdcov) is a novel coronavirus that causes diarrhea in nursing piglets. following its first detection in the united states in february 2014, additional pdcov strains have been identified in the united states and canada. currently, no treatments or vaccines for pdcov are available. in this study, u.s. pdcov strain oh-fd22 from intestinal contents of a diarrheic pig from ohio was isolated in swine testicular (st) and llc porcine kidney (llc-pk) cell cultures by using vario ...201525740769
detection and genetic characterization of deltacoronavirus in pigs, ohio, usa, 2014.in ohio, united states, in early 2014, a deltacoronavirus was detected in feces and intestine samples from pigs with diarrheal disease. the complete genome sequence and phylogenetic analysis of the virus confirmed that the virus is closely related to a porcine deltacoronavirus (porcine coronavirus hku15) reported in hong kong in 2012.201424964136
origin, evolution, and virulence of porcine deltacoronaviruses in the united states.a novel porcine deltacoronavirus (pdcv) was first discovered in ohio and indiana in february 2014, rapidly spread to other states in the united states and canada, and caused significant economic loss in the swine industry. the origin and virulence of this novel porcine coronavirus are not known. here, we characterized u.s. pdcv isolates and determined their virulence in gnotobiotic and conventional piglets. genome analyses revealed that u.s. pdcv isolates possess unique genetic characteristics a ...201525759498
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